Triple Strength Pancreatin 4X 375 mg Ingredients & Drug Interactions
by Swanson
What is this page for?
First and foremost: checking Triple Strength Pancreatin 4X 375 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Triple Strength Pancreatin 4X 375 mg is a dietary supplement by Swanson with 3 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Triple Strength Pancreatin 4X 375 mg by Swanson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains three active ingredients — all digestive enzymes that help break down food. Protease breaks down proteins, lipase handles fats, and amylase works on starches.
Together, they're meant to ease digestion. The product also contains several inactive ingredients (calcium carbonate, whey, stearic acid, magnesium stearate, and an enteric coating) that help the tablet hold together and release in your digestive tract.
Does it work?
Not established
The evidence for these enzymes is limited. For lipase specifically, the data we hold rates its effectiveness as insufficient for inflammatory bowel disease, dyspepsia (indigestion), and prematurity — meaning we don't have strong enough evidence to say whether it works for these conditions.
We don't have effectiveness ratings on file for protease or amylase. If you're considering this product for a specific digestive concern, talk with your pharmacist or doctor about what the evidence actually shows for your situation.
How safe is it?
Well-documented data
Protease and lipase are generally well tolerated in supplement form, but both can occasionally cause digestive upset or allergic reactions. Protease can rarely trigger allergic responses, especially in people with occupational exposure to airborne enzymes.
Lipase is usually gentle, though people with serious digestive conditions should use it only under medical guidance. During pregnancy, protease isn't recommended — safety hasn't been established.
Lipase has little safety data in pregnancy, so use only if your doctor advises it. For breastfeeding, neither ingredient has been well studied; check with your healthcare provider first.
We don't have safety data on file for amylase.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. Use the medication interaction checker below with your specific prescriptions and over-the-counter drugs to be certain.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
This pancreatin blend is for people looking to support digestion with enzymes. It's generally well tolerated, but if you have a serious digestive condition, pregnant, or breastfeeding, talk with your pharmacist or doctor first.
No interactions with medications are documented for the ingredients we could check — but run your exact medications through the tool on this page to be sure.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 28, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Triple Strength Pancreatin 4X 375 mg, straight from the product label.
| Brand | Swanson |
|---|---|
| Barcode (UPC) | 087614012872 |
| Net contents | 300 Enteric-Coated Tablet(s) |
| Market status | On market |
| Date entered into DSLD | May 28, 2019 |
| DSLD ID | 202489 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Triple Strength Pancreatin 4X 375 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Pancreatin | 750 mg | -- |
Other ingredients: Calcium Carbonate, Whey, Stearic Acid, Magnesium Stearate, Enteric Coating
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Provides lipase for ideal fat metabolism
General Statements
Supports healthy digestion and maximizes nutrient absorption Provides protease-rich digestive enzymes for improved protein breakdown Science-Backed Quality Since 1969
Digestive health 375 mg per tablet
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take one or two tablets with water one-half hour before each meal.
Precautions
Warning: For adults only.
Consult your physician before use if you are pregnant or nursing, taking medication, or have a medical condition.
Keep out of reach of children.
Do not use if seal is broken.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General
SW287 Rev 2 08 08 18
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Triple Strength Pancreatin 4X 375 mg by Swanson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Triple Strength Pancreatin 4X 375 mg by Swanson
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container150 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Calcium Carbonate, Whey, Stearic Acid, Magnesium Stearate, Enteric Coating. These complete the product’s ingredient list but are not active constituents.
Triple Strength Pancreatin 4X 375 mg by Swanson Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Triple Strength Pancreatin 4X 375 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Triple Strength Pancreatin 4X 375 mg, from the product label.
Swanson
See all Swanson products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- swanson.com
Triple Strength Pancreatin 4X 375 mg by Swanson: Common Questions
Does Triple Strength Pancreatin 4X 375 mg by Swanson interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What are these enzymes supposed to do?
Can I take this if I'm pregnant?
Can I use this while breastfeeding?
What side effects might I notice?
Will this work for my condition?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Triple Strength Pancreatin 4X 375 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Triple Strength Pancreatin 4X 375 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph →Sources & How We Checked
Triple Strength Pancreatin 4X 375 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC