Turkesterone & Tongkat Ali Ingredients & Drug Interactions
by HUMANX
What is this page for?
First and foremost: checking Turkesterone & Tongkat Ali against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Turkesterone & Tongkat Ali is a dietary supplement by HUMANX with 3 active ingredients. Its ingredients are commonly taken for cough and respiratory symptoms, sore throat, fever.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tongkat Ali Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Turkesterone & Tongkat Ali by HUMANX
Ask about any prescription or over-the-counter medication and we check it for interactions with Turkesterone & Tongkat Ali by HUMANX — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Turkesterone & Tongkat Ali by HUMANX
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product has 3 active ingredients. The primary ones are Ajuga turkestanica Extract (also called turkesterone) and Tongkat Ali Root Extract, both botanical compounds traditionally used to support physical performance and vitality.
The formula also contains Colostrum, a nutrient-rich secretion from early milk. The only inactive ingredient listed is methylcellulose, a binder that holds the capsule together.
Does it work?
Leans against
Tongkat Ali has been studied for sexual desire and is rated possibly effective for that use. For athletic performance, the evidence doesn't support its use — it's rated possibly ineffective.
For back pain, osteoporosis, and diabetes, we don't have enough reliable evidence to make a rating. We hold no effectiveness data for the turkesterone or colostrum in this product.
How safe is it?
Well-documented data
Tongkat Ali is generally well tolerated in short-term studies, but long-term safety isn't well established, and the quality of supplements can vary. Because this ingredient may increase testosterone levels, it should be avoided during pregnancy and breastfeeding — there isn't enough safety data for either stage.
If testosterone is raised beyond normal, you could experience acne, insulin resistance, liver strain, or other testosterone-related effects. Talk with your doctor or pharmacist if you have concerns about hormonal effects or are pregnant or nursing.
Meds to double-check
Moderate interaction found
If you're on propranolol or any beta-blocker, flag it — this product may reduce its effectiveness. Also double-check any medications metabolized by liver enzymes (CYP1A2, CYP2C19, CYP2A6) and testosterone-based treatments before taking it.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is mainly for people interested in sexual function or athletic support, though the athletic evidence is weak. If you take propranolol or any heart or blood pressure medication, blood thinners, or anything metabolized by your liver, check with us first.
Pregnant or breastfeeding? Skip it.
Have your pharmacist run this against your current medications before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Turkesterone & Tongkat Ali, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Turkesterone & Tongkat Ali by HUMANX, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 900 mg | -- |
| Ajuga turkestanica Extract, Powder | 0 NP | -- |
| Tongkat Ali Root Extract | 0 NP | -- |
| Colostrum | 0 NP | -- |
Other ingredients: Methylcellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Turkesterone & Tongkat Ali blend supports vitality & athletic performance.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take two capsules per day with a glass of water, or as recommended by your healthcare professional.
Precautions
Caution: Keep out of reach of children and pets.
Caution: Keep out of reach of children and pets. Consult with a qualified healthcare professional prior to using this product. Do not exceed recommended daily intake. do not use if safety seal is damaged or missing.
Storage
Store at room temperature, in a dry place. Protect product from excessive heat, freezing, humidity, and light.
General Statements
100% refund guarantee Refund guarantee We offer a full refund on the purchase price of your order (minus return costs) within 30 days of purchase. Restrictions apply. Please visit shophumanx.com for full details.
900 milligrams per serving
New
Formulation
Proprietary blend supports vitality & athletic performance
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Turkesterone & Tongkat Ali by HUMANX label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Turkesterone & Tongkat Ali by HUMANX
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Ajuga turkestanica Extract, Powder
- › Tongkat Ali Root Extract
- › Colostrum
Other (inactive) ingredients: Methylcellulose. These complete the product’s ingredient list but are not active constituents.
Turkesterone & Tongkat Ali by HUMANX Drug Interactions
HelloPharmacist Interaction Report
Turkesterone & Tongkat Ali by HUMANX contains one ingredient with documented drug interactions: Tongkat Ali Root Extract.
The most serious interaction is with propranolol (Inderal), a beta-blocker used for heart rhythm and blood pressure control. Taking this product with propranolol may reduce the drug's effectiveness by lowering its blood levels — a moderate-severity concern you'll want to discuss with your prescriber.
Read the full breakdown — every affected drug type, severity by severity
Tongkat Ali can also theoretically increase blood levels of several other medication types through liver enzyme effects (CYP1A2, CYP2C19, and CYP2A6 substrates). These are minor-severity interactions based on lab evidence; human data is lacking.
Additionally, if you're taking testosterone replacement or medications that raise testosterone, this ingredient may further boost your testosterone levels, which carries a minor-severity risk.
We could not check two other ingredients in this product — Ajuga turkestanica Extract and Colostrum — because interaction data isn't on file for them. Altogether, these interactions span 248 individual medications.
Run your exact prescriptions through the interaction checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Turkesterone & Tongkat Ali?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Turkesterone & Tongkat Ali interact with 248 drugs. Click any drug to see the details.
1 of the 3 ingredients in Turkesterone & Tongkat Ali interact with drugs. Each result below shows which ingredient is responsible. Tongkat Ali Root Extract
Hydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Root Extract + Hydrochlorothiazide, Propranolol interactionPropranololAngilol, Bedranol SR, Beta Prograne, Half Beta Prograne, Half-Inderal LA, Inderal +6 more
How Propranolol interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Root Extract + Propranolol interactionPropranolol HydrochlorideHemangeol
How Propranolol Hydrochloride interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Root Extract + Propranolol Hydrochloride interactionAbrocitinibCibinqo
How Abrocitinib interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Tongkat Ali Root Extract + Abrocitinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Turkesterone & Tongkat Ali — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Root Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Turkesterone & Tongkat Ali with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Tongkat Ali Root Extract
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Brand information
Manufacturer and brand details for Turkesterone & Tongkat Ali, from the product label.
HUMANX
See all HUMANX products- Name
- Ilumina LLC
- Street Address
- 302 Washington St #151
- City
- San Diego
- State
- CA
- ZipCode
- 92103
- Web Address
- www.shophumanx.com
Turkesterone & Tongkat Ali by HUMANX: Common Questions
Does Turkesterone & Tongkat Ali by HUMANX interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What's turkesterone, and what's it supposed to do?
Can I take this while pregnant or breastfeeding?
Does Tongkat Ali actually work for sexual function?
Will this help my athletic performance?
Can this raise my testosterone too high?
What's colostrum, and why is it in here?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Turkesterone & Tongkat Ali is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Turkesterone & Tongkat Ali’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Ajuga Nipponensis
Ajuga nipponensis is a perennial plant from East Asia used in traditional medicine for cough and respiratory complaints. There is very little human research to confirm any health benefits, s...
Read the full Ajuga Nipponensis monograph → Herb & supplement monographEurycoma Longifolia
Interacts with 248 drugsEurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....
Read the full Eurycoma Longifolia monograph →Sources & How We Checked
Turkesterone & Tongkat Ali's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Ajuga Nipponensis 1 reference
- Liao SC, Chiu TF, Chen JC, Lin CC. Ajuga nipponensis Makino poisoning. Clin Toxicol (Phila) 2005;43:583-5.
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
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