Urinary Bladder Support Ingredients & Drug Interactions
by Hawaii Pharm
What is this page for?
First and foremost: checking Urinary Bladder Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Urinary Bladder Support is a dietary supplement by Hawaii Pharm with 4 active ingredients. Its ingredients are commonly taken for cough and sore throat, dry mouth and throat irritation, digestive upset and heartburn.Based on those ingredients, 2,143 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow Leaf Extract, Dry, Uva Ursi Herb Extract, Dry, Corn Silk Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Urinary Bladder Support by Hawaii Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Urinary Bladder Support by Hawaii Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Urinary Bladder Support by Hawaii Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Urinary Bladder Support contains 4 active ingredients: marshmallow leaf extract, corn silk extract, couch grass root extract, and uva ursi herb extract, all in dry form as part of a proprietary blend. These are mixed with alcohol, water, and glycerin as inactive ingredients (the liquid base and preservative).
The product is designed to support urinary and bladder health through these botanical extracts.
Does it work?
Leans against
The evidence base for this product's active ingredients is limited. Marshmallow leaf has insufficient reliable evidence for the conditions studied (including vaginal yeast infections, diarrhea, eczema, and respiratory infections).
Corn silk similarly shows insufficient evidence for uses like heart disease, diabetes, and depression. Uva ursi is rated possibly ineffective for urinary tract infections — the very condition this product appears aimed at — and has insufficient evidence for bronchitis and prostate health.
Couch grass effectiveness data are not on file with us. None of these ingredients are proven effective for bladder support in the data we hold.
How safe is it?
Well-documented data
Marshmallow leaf and couch grass are generally well tolerated short-term, though human safety data are sparse. Corn silk is also generally well tolerated short-term; the most common adverse effects with prolonged use are low potassium and low sodium.
Uva ursi is well tolerated in low doses for short periods but can be toxic at high doses — doses of 20 grams or more of dried herb have caused serious effects like seizures, confusion, and shortness of breath, and very high doses (30 grams or more) may be fatal. Common side effects include nausea, vomiting, diarrhea, and stomach upset.
During pregnancy, marshmallow leaf and couch grass lack enough safety data and are best avoided; uva ursi is rated likely unsafe and should be avoided. While breastfeeding, marshmallow and uva ursi are best avoided due to insufficient safety information; corn silk is possibly safe.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take blood pressure medications, blood sugar medications, corticosteroids, diuretics, warfarin, lithium, or any medications metabolized by the liver (ask your pharmacist if unsure). Moderate interactions are documented for all of these drug types.
Also space this product at least 30–60 minutes away from any oral medications you take by mouth, since marshmallow may slow their absorption.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines four botanical extracts intended for urinary and bladder support, but the evidence that any of them work for this purpose is not established in the data we hold. More importantly, the product carries multiple moderate interactions — chiefly with blood pressure and blood sugar drugs, water pills, warfarin, lithium, and several types of liver-metabolized medications.
If you take any prescription medication, especially for blood pressure, diabetes, heart rhythm, or blood thinning, talk with your doctor or pharmacist before starting this product.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Urinary Bladder Support, straight from the product label.
| Brand | Hawaii Pharm |
|---|---|
| Barcode (UPC) | 840253664150 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2023 |
| DSLD ID | 301953 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Urinary Bladder Support by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 983 mg | -- |
| Marshmallow Leaf Extract, Dry | 0 NP | -- |
| Corn Silk Extract, Dry | 0 NP | -- |
| Couch Root Extract, Dry | 0 NP | -- |
| Uva Ursi Herb Extract, Dry | 0 NP | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Hawaii Pharm Herbal Extract Highest quality since 2008
Suggested/Recommended/Usage/Directions
Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.
Precautions
Warning: We recommend to seek expert medical advice before taking.
Do not use if you are allergic to any ingredients.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.
Keep out of the reach of children!
Storage
Store in a cool dry place.
Seals/Symbols
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Organic Alcohol Based USA Made in United States of America
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Made in USA, Hawaii
Only natural ingredients Purity is laboratory tested and verified
All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives
Not tested on animals
Organic Alcohol Based
FDA Statement of Identity
Herbal Supplement
Formula
Organic Alcohol Based
General Statements
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Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Urinary Bladder Support by Hawaii Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Urinary Bladder Support by Hawaii Pharm
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Urinary Bladder Support by Hawaii Pharm Drug Interactions
HelloPharmacist Interaction Report
Urinary Bladder Support by Hawaii Pharm has documented interactions with multiple medication types through its marshmallow leaf, corn silk, and uva ursi content.
The most serious interaction is a Moderate risk with lithium — both marshmallow and uva ursi may theoretically reduce lithium excretion and raise its levels in your blood, risking lithium toxicity and potentially requiring a dose adjustment.
Read the full breakdown — every affected drug type, severity by severity
Corn silk carries Moderate interactions with blood pressure drugs (antihypertensive medications), steroids (corticosteroids), blood sugar drugs (antidiabetes medications), water pills (diuretics), and warfarin. Corn silk can lower blood pressure and blood sugar, increase potassium loss, and contains vitamin K, which can interfere with warfarin's blood-thinning effect if your intake is inconsistent.
Uva ursi also has Moderate interactions with drugs metabolized by your liver (CYP2C19 and CYP3A4 substrates), glucuronidated drugs, and drugs that work by a kidney transport system (P-glycoprotein substrates) — these are largely theoretical and not yet confirmed in humans. Uva ursi can also reduce the effects of urinary acidifying agents.
Marshmallow carries a Minor interaction with oral medications generally, since its mucilage may slow drug absorption; space it 30–60 minutes after taking other drugs by mouth.
We could not check couch grass root extract — we hold no interaction data for it. Altogether, these interactions span 2,144 individual medications.
Use the medication checker on this page to look up your specific prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Urinary Bladder Support?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Urinary Bladder Support interact with 2,143 drugs. Click any drug to see the details.
3 of the 4 ingredients in Urinary Bladder Support interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Leaf Extract, Dry Uva Ursi Herb Extract, Dry Corn Silk Extract, Dry
GabapentinGralise, Neurontin
How Gabapentin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gabapentin interactionGabapentin EnacarbilHorizant
How Gabapentin Enacarbil interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gabapentin Enacarbil interactionGadobenate DimeglumineMultihance
How Gadobenate Dimeglumine interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gadobenate Dimeglumine interactionGallamineFlaxedil
How Gallamine interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gallamine interactionGamma Hydroxybutyrate (prescription Drug)GHB
How Gamma Hydroxybutyrate (prescription Drug) interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gamma Hydroxybutyrate (prescription Drug) interactionGanciclovirCytovene, Cytovene Injection
How Ganciclovir interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Ganciclovir interactionGatifloxacinTequin, Tequin Injection
How Gatifloxacin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gatifloxacin interactionGemfibrozilLopid
How Gemfibrozil interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gemfibrozil interactionGemifloxacinFactive
How Gemifloxacin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gemifloxacin interactionGemtuzumabMylotarg
How Gemtuzumab interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gemtuzumab interactionGentian Violet (otc Drug)Gentian Violet
How Gentian Violet (otc Drug) interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gentian Violet (otc Drug) interactionGestodeneMinesse
How Gestodene interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Gestodene interactionGlutethimideDoriden
How Glutethimide interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Glutethimide interactionGlycerinOsmoglyn
How Glycerin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Glycerin interactionGlycerol PhenylbutyrateRavicti
How Glycerol Phenylbutyrate interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Glycerol Phenylbutyrate interactionGlycine (prescription Drug)Glycine Irrigation
How Glycine (prescription Drug) interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Glycine (prescription Drug) interactionGlycopyrrolateDartisla ODT, Glycopyrrolate Injection, Glyrx-Pf, Lonhala Magnair Kit, Robinul, Robinul Forte +1 more
How Glycopyrrolate interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Glycopyrrolate interactionGoserelinZoladex
How Goserelin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Goserelin interactionGranisetronKytril, Sustol
How Granisetron interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Granisetron interactionGrepafloxacinRaxar
How Grepafloxacin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Grepafloxacin interactionGriseofulvinFulvicin PG, Fulvicin-U/F, Grisactin, Grisactin Ultra
How Griseofulvin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Griseofulvin interactionGuafenesinDuravent
How Guafenesin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Guafenesin interactionGuaifenesinAmibid LA, Bidex, Humibid LA, Mucinex, Muco-Fen 800, Numobid +3 more
How Guaifenesin interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Guaifenesin interactionGuaifenesin, OxtriphyllineBrondecon
How Guaifenesin, Oxtriphylline interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Guaifenesin, Oxtriphylline interactionGuaifenesin, PhenylephrineAmidal, Deconsal Ped, Deconsal Sprinkle, Endal, Liquibid-D, Numonyl Sr +1 more
How Guaifenesin, Phenylephrine interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Guaifenesin, Phenylephrine interactionGuaifenesin, Phenylephrine, PhenylpropanolamineDura Gest, Entex
How Guaifenesin, Phenylephrine, Phenylpropanolamine interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Guaifenesin, Phenylephrine, Phenylpropanolamine interactionGuaifenesin, PhenylpropanolamineBanex LA, Dura-Vent, Entex LA, Guaifed, Guaifed-PD, Guaipax SR +1 more
How Guaifenesin, Phenylpropanolamine interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Guaifenesin, Phenylpropanolamine interactionGuaifenesin, PseudoephedrineAmi-tex PSE, Aquabid D, Aquatab D, Cephadyn, Congestac, D Feda II +34 more
How Guaifenesin, Pseudoephedrine interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Guaifenesin, Pseudoephedrine interactionGuaifenesin, TheophyllineBronchial, Mudrane GG-2, Quibron, Quibron-300, Theolair-Plus
How Guaifenesin, Theophylline interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Guaifenesin, Theophylline interactionHalazepamPaxipam
How Halazepam interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Marshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Halazepam interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Urinary Bladder Support with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Marshmallow Leaf Extract, Dry
Lithium
Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.
Anticoagulant/Antiplatelet Drugs
Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.
Oral Drugs
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.
Uva Ursi Herb Extract, Dry
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.
Glucuronidated Drugs
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.
Lithium
Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.
Urinary Acidifying Agents
Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.
P-Glycoprotein Substrates
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
Corn Silk Extract, Dry
Antidiabetes Drugs
Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.
Antihypertensive Drugs
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.
Corticosteroids
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.
Diuretic Drugs
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.
Warfarin (Coumadin)
Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.
Brand information
Manufacturer and brand details for Urinary Bladder Support, from the product label.
Hawaii Pharm
See all Hawaii Pharm products- Name
- Hawaii Pharm LLC
- Street Address
- 510 Sumner St. Ste. 613
- City
- Honolulu
- State
- HI
- ZipCode
- 96817
- Phone Number
- 888-854-2924
- Web Address
- www.hawaiipharm.com
Urinary Bladder Support by Hawaii Pharm: Common Questions
Does Urinary Bladder Support by Hawaii Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on blood pressure medication?
Is it safe to take while pregnant?
What are the side effects of uva ursi?
Can I take this with warfarin?
Does this product actually work for bladder problems?
Can I take this while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Urinary Bladder Support is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Urinary Bladder Support’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Marshmallow
Interacts with 2,040 drugsMarshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...
Read the full Marshmallow monograph → Herb & supplement monographCorn Silk
Interacts with 290 drugsCorn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...
Read the full Corn Silk monograph → Herb & supplement monographCouch Grass
Couch grass is a common lawn weed whose rhizome has long been used in traditional European herbal medicine, mainly for urinary and bladder complaints. High-quality human studies are lacking,...
Read the full Couch Grass monograph → Herb & supplement monographUva Ursi
Interacts with 803 drugsUva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial effects in the urine. Evidence in people...
Read the full Uva Ursi monograph →Sources & How We Checked
Urinary Bladder Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Marshmallow 5 references
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.
Corn Silk 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
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