No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Usnea Ingredients & Drug Interactions

by Herbs Etc.

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Usnea is a dietary supplement by Herbs Etc. with 1 active ingredient. Its ingredients are commonly taken for sore throat, skin and wound care, respiratory infections.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Usnea by Herbs Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: usnea, a type of lichen. It's supplied as a liquid extract in grain alcohol and purified water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Usnea product and its label doesn't state a use — see Usnea's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for usnea isn't established in our data. We hold ratings of insufficient reliable evidence for cough, pain, wound healing, tinea pedis (a fungal foot infection), and obesity — meaning the research backing its use for those conditions isn't strong enough yet to make a clear call.

The evidence, ingredient by ingredient Usnea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's where you need to pay attention: oral usnea carries a liver safety concern. The usnic acid it contains has been linked to liver damage, so this isn't a product to take long-term or without knowing your liver is healthy.

Topical usnea is generally well tolerated, but this is taken by mouth. This product is not recommended during pregnancy or while breastfeeding — there isn't enough safety data.

If you're in either of those situations, talk with your pharmacist or doctor before considering it.

Side effects, ingredient by ingredient Usnea

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredient we could check. That doesn't mean none could occur — it means we don't have that data on file.

Check your exact medications with the tool on this page, and mention to your pharmacist that you're considering an oral usnea product.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Usnea is generally well tolerated when applied to skin, but this liquid form is meant to be taken internally, where the liver concern becomes real. If you're thinking about taking it for cough, pain, or wound healing, know that the evidence for those uses isn't solid yet.

Talk with your pharmacist before starting, especially if you have any liver issues or take other supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Usnea, straight from the product label.

Brand Herbs Etc.
Net contents 8 fl. Oz.; 236 mL
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 50680
Product type Botanical
Supplement form Liquid
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Usnea by Herbs Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Not Present
Maximum serving Sizes:
0 Not Present
IngredientAmount% DV
Usnea0 NP--

Other ingredients: 73% Grain Alcohol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Herbal Single

Professional strength

Dried lichen extract

For dispensing purposes only

Formula

Usnea barbata

FDA Statement of Identity

Fast-Acting Dietary Supplement

General

99216

See for yourself

Usnea by Herbs Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Usnea by Herbs Etc.

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0 Not Present Dosage formLiquid Amounts shown are per serving.

Usnea

No known
interactions
0 NP per serving

Usnea is a lichen used in traditional herbal medicine, mainly for sore throats, skin infections, and as a general antimicrobial. Laboratory studies su...

Usnea monograph & interactions

Other (inactive) ingredients: 73% Grain Alcohol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Usnea by Herbs Etc. Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Usnea. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Usnea, from the product label.

Herbs Etc.

Name
Herbs, Etc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Usnea by Herbs Etc.: Common Questions

Does Usnea by Herbs Etc. interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Usnea. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Usnea contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take by mouth?
Usnea taken orally may be unsafe — specifically, usnic acid, a compound in usnea, has been linked to liver damage. Topical forms are generally better tolerated. If you have any liver concerns or take medications that affect your liver, talk with your pharmacist first.
Can I use this while pregnant or breastfeeding?
No. The safety data isn't there for either pregnancy or breastfeeding, so it's advised to avoid this product in both situations. Talk with your doctor or pharmacist about alternatives if you need support for cough or pain during that time.
What does usnea actually treat?
We don't have reliable evidence yet for usnea's effectiveness at treating cough, pain, wound healing, fungal foot infections, or obesity. That doesn't mean it doesn't work — it means the research backing those uses needs to be stronger before we can say either way.
Does this ingredient interact with my medications?
No interactions are documented in our data for usnea. Use the interaction checker on this page with your exact medication list to be sure, and mention to your pharmacist that you're considering starting it.
What are the side effects?
We don't have a lot of information on side effects from taking it by mouth. When applied to skin, usnic acid (a compound in usnea) can cause contact dermatitis, local irritation, or in rare cases allergic reactions with respiratory symptoms and conjunctivitis.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Usnea is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Usnea label
Go deeper

The Full Monographs Behind Usnea’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Usnea's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Usnea 10 references
  1. Favreau JT, Ryu Ml, Braunstein G, et al. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann Intern Med 2002;136:590-5. PubMed
  2. Ingolfsdottir K. Usnic acid. Phytochemistry 2002;61:729-36.
  3. Scirpa, P., Scambia, G., Masciullo, V., Battaglia, F., Foti, E., Lopez, R., Villa, P., Malecore, M., and Mancuso, S. [A zinc sulfate and usnic acid preparation used as post-surgical adjuvant therapy in genital lesions by Human Papillomavirus]. Minerva Gin
  4. Mitchell, J. C. Allergy to lichens. Allergic contact dermatitis from usnic acid produced by lichenized fungi. Arch Dermatol 1965;92(2):142-146.
  5. Durazo, F. A., Lassman, C., Han, S. H., Saab, S., Lee, N. P., Kawano, M., Saggi, B., Gordon, S., Farmer, D. G., Yersiz, H., Goldstein, R. L., Ghobrial, M., and Busuttil, R. W. Fulminant liver failure due to usnic acid for weight loss. Am.J Gastroenterol. PubMed
  6. Neff, G. W., Reddy, K. R., Durazo, F. A., Meyer, D., Marrero, R., and Kaplowitz, N. Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid. J Hepatol. 2004;41(6):1062-1064. PubMed
  7. Hsu, L. M., Huang, Y. S., Chang, F. Y., and Lee, S. D. 'Fat burner' herb, usnic Acid, induced acute hepatitis in a family. J Gastroenterol.Hepatol. 2005;20(7):1138-1139. PubMed
  8. Arneborn, P., Jansson, A., and Bottiger, Y. [Acute hepatitis in a woman after intake of slimming pills bought via Internet]. Lakartidningen 7-11-2005;102(28-29):2071-2072.
  9. Sanchez, W., Maple, J. T., Burgart, L. J., and Kamath, P. S. Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid. Mayo Clin Proc 2006;81(4):541-544. PubMed
  10. Rafanelli, S., Bacchilega, R., Stanganelli, I., and Rafanelli, A. Contact dermatitis from usnic acid in vaginal ovules. Contact Dermatitis 1995;33(4):271-272. PubMed

See these in context on the Usnea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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