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Dietary supplement

Vitamin B1 Ingredients & Drug Interactions

by Whole Foods

Vitamin B1 label
See full label image
Tablet Or Pill Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin B1 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Vitamin B1 is a dietary supplement by Whole Foods with 1 active ingredient. Its ingredients are commonly taken for preventing or treating thiamine deficiency, beriberi, wernicke-korsakoff syndrome (alcohol-related).Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Thiamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin B1 by Whole Foods

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin B1 by Whole Foods — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin B1 by Whole Foods

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: thiamine (also called vitamin B1). Thiamine is a B vitamin your body uses for energy, nerve function, and heart health.

The tablet also contains inactive ingredients like dicalcium phosphate, stearic acid, and silica that help hold it together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Thiamine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Thiamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Thiamine deficiency — rated "Effective" (Natural Medicines).
  • On file: Wernicke-Korsakoff syndrome (WKS) — rated "Effective" (Natural Medicines).
  • On file: Dysmenorrhea — rated "Possibly Effective" (Natural Medicines).

Thiamine is effective for treating thiamine deficiency and Wernicke-Korsakoff syndrome (a serious brain condition from severe B1 lack). For dysmenorrhea (period pain), there's some evidence it may help, though the data isn't as strong.

For mosquito repellent and heart failure, the evidence doesn't support its use.

The evidence, ingredient by ingredient Thiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Thiamine is generally very well tolerated when taken by mouth in normal amounts. Rarely, it may cause a skin rash or allergic reaction; injected thiamine can trigger severe allergic reactions, though that's also uncommon.

Thiamine is needed during pregnancy and breastfeeding—if you're pregnant or nursing and considering a supplement, use only the amount your doctor or midwife recommends.

Side effects, ingredient by ingredient Thiamine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Thiamine.
  • The most serious interaction on file is rated Minor.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take trimethoprim (an antibiotic sold as Proloprim), let your pharmacist know you're considering this supplement—it's a minor interaction, but we want to keep an eye on your levels. For any other prescription medications, use the checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Only minor medication interactions are documented, and safety information is well characterized.

Vitamin B1 is a solid choice if you have a thiamine deficiency or need extra B1 for a specific reason your provider mentioned. If you take trimethoprim or other antibiotics, check with us first.

Otherwise, it's a low-risk supplement to discuss with your pharmacist or doctor as part of your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin B1, straight from the product label.

Brand Whole Foods
Barcode (UPC) 099482283087
Net contents 100 Tablet(s); 100 mg
Market status On market
Date entered into DSLD Aug 24, 2012
DSLD ID 12097
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin B1 by Whole Foods, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
099482283087
IngredientAmount% DV
Thiamine100 mg6667%

Other ingredients: Dicalcium Phosphate, Stearic Acid, Silicon Dioxide, Magnesium Stearate, Croscarmellose Sodium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Tamper evident; use only if seal is intact.

Note: If you are pregnant or lactating, consult your health care practitioner before using this product.

Keep out of reach of children.

General Statements

PLEASE RECYCLE THIS BOTTLE

Essential B-Vitamin

Good Manufacturing Practices used to segregate in a facility that also processes milk, egg, fish, shellfish, tree nut, wheat and soy ingredients.

Please recycle bottle.

Seals/Symbols

100% PCR Post Consumer Recycled Bottle

Formulation

vegetarian

Contains no artificial colors, flavors or preservatives.

FDA Statement of Identity

vitamin supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

(C)2007 WHOLE FOODS MARKET IP, LP

Suggested/Recommended/Usage/Directions

Directions: Take 1 tablet daily with a meal.

Storage

Store in a cool, dry place.

General

228308 401228308-B

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin B1 by Whole Foods label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin B1 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin B1 by Whole Foods

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Thiamine

Interacts with
3 drugs
100 mg per serving Form: Thiamine Mononitrate

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Stearic Acid, Silicon Dioxide, Magnesium Stearate, Croscarmellose Sodium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin B1 by Whole Foods Drug Interactions

Want to check YOUR meds against Vitamin B1?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Thiamine 3

Individual Drug Interactions

The ingredients in Vitamin B1 interact with 3 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin B1 interact with drugs. Each result below shows which ingredient is responsible. Thiamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin B1 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Thiamine1 drug type · 3 drugs

Trimethoprim (Proloprim)

Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.

Likelihood Probable Evidence B
Thiamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin B1, from the product label.

Whole Foods

See all Whole Foods products
Name
Whole Foods Market
Street Address
550 Bowie Street
City
Austin
State
TX
ZipCode
78703
Web Address
www.wholefoodsmarket.com
Pharmacist Counseling Corner

Vitamin B1 by Whole Foods: Common Questions

Does Vitamin B1 by Whole Foods interact with any medications?
Yes. Based on its ingredients, Vitamin B1 has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin B1 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
Thiamine is needed during pregnancy and breastfeeding. If you're considering a supplement, talk to your doctor or midwife about the right dose for you—use only what they recommend, not more.
What's thiamine actually for?
Thiamine is a B vitamin that helps your body turn food into energy and keeps your nerves and heart working right. A deficiency can cause serious problems like Wernicke-Korsakoff syndrome, a brain condition.
Can this really help with period pain?
There's some evidence thiamine may help with dysmenorrhea (period pain), but the data isn't as solid as it is for deficiency. Talk to your doctor if you're thinking of trying it for that reason.
Are there any side effects?
Taken by mouth, thiamine is very safe. Rarely, people have had a rash or allergic reaction. Injected thiamine is even less common but can cause severe allergic reactions in very rare cases.
Does this product have fillers?
Yes, it has inactive ingredients like dicalcium phosphate, stearic acid, silicon dioxide, and magnesium stearate that help make the tablet stable. If you're sensitive to any of those, check the label or ask us.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin B1 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin B1 label
Go deeper

The Full Monographs Behind Vitamin B1’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Thiamine

Interacts with 3 drugs

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get enough from food, but supplements are clear...

Read the full Thiamine monograph →
Sources

Sources & How We Checked

Vitamin B1's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thiamine 7 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  4. Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
  5. Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
  6. Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
  7. Vora B, Wen A, Yee SW, et al. The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction. Clin Pharmacol Ther 2023;114(2):381-392.

See these in context on the Thiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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