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Dietary supplement

Vitamin K2 300 mcg MK-7 Ingredients & Drug Interactions

by Innerzyme

Vitamin K2 300 mcg MK-7 label
See full label image
Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin K2 300 mcg MK-7 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin K2 300 mcg MK-7 is a dietary supplement by Innerzyme with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2 MK-7. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin K2 300 mcg MK-7 by Innerzyme

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin K2 300 mcg MK-7 by Innerzyme — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin K2 300 mcg MK-7 by Innerzyme

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vitamin K2 as MK-7 (a form of vitamin K), dosed at 300 micrograms per capsule. Vitamin K is a fat-soluble vitamin your body needs to produce clotting proteins and support bone health.

The capsule also contains inactive ingredients — vegetable-based fillers and binders (HPMC, vegetable magnesium stearate, microcrystalline cellulose, and silicon dioxide) — that help form and preserve the supplement.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports healthy cardiovascular function and bone.
  • We looked for evidence on: Cardiovascular disease (CVD), Osteoporosis, Hemorrhagic disease, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation, bone mineralization — and 1 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

The evidence supports vitamin K for several uses. It's rated effective for correcting clotting disorders — specifically, for low blood levels of clotting factors (hypoprothrombinemia and vitamin K-dependent clotting factors deficiency) — and for bleeding conditions (hemorrhagic disease).

It's also rated effective for managing patients on warfarin therapy. For bone health, the data shows vitamin K is possibly effective for osteoporosis, meaning there's some promising evidence but it's not yet conclusive.

Talk with your doctor about whether this supplement is right for your specific health goals.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K is generally well tolerated in healthy people at dietary amounts and typical supplement doses. The most common side effects are mild gastrointestinal effects — some people experience nausea, stomach upset, abdominal pain, or diarrhea.

Pregnancy and lactation: vitamin K2 is rated likely safe during pregnancy and breastfeeding. However, because you're taking a supplement rather than getting vitamin K from food alone, it's wise to discuss this with your doctor or pharmacist for personalized guidance during pregnancy or while nursing.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take warfarin (Coumadin) or any other blood thinners (anticoagulants). Vitamin K can reduce their effectiveness, and your prescriber may need to adjust your dose or monitor you more closely.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Vitamin K2 MK-7 is a straightforward supplement for people concerned about bone health or clotting status — but it's a non-negotiable check if you take warfarin or other blood thinners. If you do take a blood thinner, talk with your doctor or pharmacist before starting this product; they'll advise whether it's safe for you or if your medication needs adjusting.

For others, it's generally well tolerated, though mild stomach upset can happen.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin K2 300 mcg MK-7, straight from the product label.

Brand Innerzyme
Barcode (UPC) 816571019965
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2019
DSLD ID 203530
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin K2 300 mcg MK-7 by Innerzyme, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
816571019965
IngredientAmount% DV
Vitamin K2 MK-7300 mcg--

Other ingredients: HPMC, Vegetable Magnesium Stearate, Vegetable Microcrystalline Cellulose, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Suggested Use: Take 1 vegetarian capsule per day, or as directed by your healthcare practitioner.

Precautions

Warnings: If you have a health condition, are pregnant, nursing, lactating, trying to become pregnant or taking any medications (especially anticoagulants), consult your healthcare practitioner before using this product.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Made in the USA

Supports Healthy Cardiovascular Function Bone and Soft Tissue

Manufactured in a GMP facility

Formula

Optimum Quality K2

FDA Statement of Identity

Dietary Supplement

Formulation

Non-GMO

Not manufactured with gluten, dairy, yeast or wheat.

General

INR-019965

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin K2 300 mcg MK-7 by Innerzyme label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin K2 300 mcg MK-7 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin K2 300 mcg MK-7 by Innerzyme

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Vitamin K2 MK-7

Interacts with
2 drugs
300 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 MK-7 monograph & interactions

Other (inactive) ingredients: HPMC, Vegetable Magnesium Stearate, Vegetable Microcrystalline Cellulose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin K2 300 mcg MK-7 by Innerzyme Drug Interactions

Want to check YOUR meds against Vitamin K2 300 mcg MK-7?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 MK-7 2

Individual Drug Interactions

The ingredients in Vitamin K2 300 mcg MK-7 interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin K2 300 mcg MK-7 interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2 MK-7

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin K2 300 mcg MK-7 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K2 MK-71 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 MK-7 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin K2 300 mcg MK-7, from the product label.

Innerzyme

See all Innerzyme products
Name
Innerzyme
Street Address
PO Box 26465
City
Scottsdale
State
AZ
ZipCode
85255
Phone Number
(480) 284-8478
Web Address
www.innerzyme.com
Pharmacist Counseling Corner

Vitamin K2 300 mcg MK-7 by Innerzyme: Common Questions

Does Vitamin K2 300 mcg MK-7 by Innerzyme interact with any medications?
Yes. Based on its ingredients, Vitamin K2 300 mcg MK-7 has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin K2 300 mcg MK-7 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is MK-7, and why is it different from other forms of vitamin K?
MK-7 is a specific form of vitamin K2, a type that your body can use and store more efficiently than some other forms. The facts we hold don't detail how MK-7 compares to MK-4 or K1, but MK-7 at 300 mcg is a well-studied dose.
Can I take this if I'm on warfarin?
Not without talking to your doctor first. Vitamin K directly counteracts warfarin's blood-thinning effect, so your prescriber needs to know you're considering it and may adjust your dose or monitor your blood work. This is a Major interaction — don't skip this conversation.
Will this supplement help my bones?
The evidence suggests vitamin K may help with osteoporosis, but it's rated possibly effective — not yet proven conclusively. Ask your doctor whether it makes sense as part of your bone health plan.
What are the side effects?
Taken by mouth, vitamin K is generally well tolerated. The most common side effects are mild — nausea, stomach upset, abdominal pain, or diarrhea — and they occur in a small number of people.
Is it safe to take while I'm pregnant or breastfeeding?
Yes, vitamin K is rated likely safe during pregnancy and lactation. That said, because you're taking a supplement rather than relying on food, talk with your doctor or pharmacist to make sure it's the right choice for you individually.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin K2 300 mcg MK-7 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin K2 300 mcg MK-7 label
Go deeper

The Full Monographs Behind Vitamin K2 300 mcg MK-7’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Vitamin K2 300 mcg MK-7's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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