White Mulberry Leaf with Cinnamon Ingredients & Drug Interactions
by ProCaps
What is this page for?
First and foremost: checking White Mulberry Leaf with Cinnamon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
White Mulberry Leaf with Cinnamon is a dietary supplement by ProCaps with 2 active ingredients. Its ingredients are commonly taken for blood sugar support, high cholesterol, weight management.Based on those ingredients, 443 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cinnamon Bark Extract Blend, White Mulberry Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against White Mulberry Leaf with Cinnamon by ProCaps
Ask about any prescription or over-the-counter medication and we check it for interactions with White Mulberry Leaf with Cinnamon by ProCaps — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of White Mulberry Leaf with Cinnamon by ProCaps
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 4 of its 4 active ingredients.
- “Cinnamon Bark Extract Blend” is a proprietary blend — the label gives one combined amount (200 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — White Mulberry.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: diabetes medications.
- For scale: 87 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about White Mulberry Leaf with Cinnamon, straight from the product label.
| Brand | ProCaps |
|---|---|
| Barcode (UPC) | 880434 |
| Net contents | 180 Easy-To-Swallow Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2025 |
| DSLD ID | 331629 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for White Mulberry Leaf with Cinnamon by ProCaps, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Flavones | 100 mg | -- |
| Proanthocyanidins | 50 mg | -- |
| Type A Polymers | 50 mg | -- |
| White Mulberry Leaf Extract | 250 mg | -- |
| Cinnamon Bark Extract Blend | 200 mg | -- |
Other ingredients: Extra Virgin Olive Oil, Gelatin, Water, Purified, Glycerin, Vitamin E
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Consume one capsule with each meal or significant snack containing carbohydrate or sugar (immediately before, during or immediately after eating) or as recommended by your physician. There is no need to consume more than four capsules daily.
General Statements
For questions about the use of this product call 800.800.1200. Questions? Orders? 800.800.1200 PROCAPS.COM Andrew Lessman
Formulation
Since 1979, Unsurpassed Purity, Quality and Efficacy. 100% Solar Production Zero-Carbon Footprint 100% Solar
Supports Healthy Blood Sugar Balance Glucose and Insulin Metabolism
WHITE MULBERRY LEAF with CINNAMON offers a blend of two focused standardized extracts to support healthy blood sugar metabolism and insulin balance. White mulberry leaf standardized to deliver a 5% extract of the natural iminosugar 1-deoxynojirimycin is perfectly partnered with our standardized cinnamon extract to support healthy blood sugar balance and glucose metabolism. These two highly respected traditional remedies are now recognized for their benefits to promote healthy blood sugar and insulin metabolism. Clinical research has shown that white mulberry leaf with its uniquely high levels of 1-deoxynojirimycin can reduce the absorption of dietary sugars and carbohydrate. Cinnamon has also gained recognition for its ability to support healthy blood sugar metabolism and insulin balance. Research attributes these benefits to the powerful polyphenols present in cinnamon bark extract. These two targeted standardized extracts of white mulberry leaf and cinnamon bark provide Mother Nature's perfect natural support to our important efforts at optimizing our blood sugar metabolism and insulin balance.
Contains no additives or common allergies Contains no Milk, soy, yeast, wheat, gluten, sodium, salt, sugar, cholesterol, color, preservative, common allergens, genetically modified (GMO) ingredients or manufacturing additives.
Brand IP Statement(s)
Copyright 2024 ProCaps Laboratories
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
White Mulberry Leaf with Cinnamon by ProCaps label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in White Mulberry Leaf with Cinnamon by ProCaps
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
White Mulberry Leaf Extract
Interacts with87 drugs
White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is gen...
White Mulberry Leaf Extract monograph & interactionsCinnamon Bark Extract Blend
Interacts with442 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Cinnamon Bark Extract Blend monograph & interactions- › Flavones
- › Proanthocyanidins
- › Type A Polymers
Other (inactive) ingredients: Extra Virgin Olive Oil, Gelatin, Water, Purified, Glycerin, Vitamin E. These complete the product’s ingredient list but are not active constituents.
White Mulberry Leaf with Cinnamon by ProCaps Drug Interactions
White Mulberry Leaf with Cinnamon contains 2 ingredients, and 2 of them have known drug interactions. Altogether they interact with 443 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against White Mulberry Leaf with Cinnamon?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in White Mulberry Leaf with Cinnamon interact with 443 drugs. Click any drug to see the details.
2 of the 2 ingredients in White Mulberry Leaf with Cinnamon interact with drugs. Each result below shows which ingredient is responsible. Cinnamon Bark Extract Blend White Mulberry Leaf Extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with White Mulberry Leaf with Cinnamon — through 2 ingredients. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Read the full Cinnamon Bark Extract Blend + Acarbose interactionWhite Mulberry Leaf ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full White Mulberry Leaf Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with White Mulberry Leaf with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Extract BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract Blend + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in White Mulberry Leaf with Cinnamon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Cinnamon Bark Extract Blend
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
White Mulberry Leaf Extract
Antidiabetes Drugs
Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that white mulberry leaf can lower blood glucose levels. Advise patients to monitor glucose levels closely.
Organic Cation Transporter 2 (Oct2) Substrates
Theoretically, white mulberry leaf might slow the elimination and increase the adverse effects of drugs which are OCT2 substrates.
Animal research shows that coadministration of white mulberry leaf extract with metformin, an OCT2 substrate, slows the renal elimination of metformin via inhibition of OCT2 activity. OCT2 is expressed in the kidneys and is responsible for transporting cationic drugs into tubular epithelial cells in order to be excreted in the urine.
Brand information
Manufacturer and brand details for White Mulberry Leaf with Cinnamon, from the product label.
ProCaps
See all ProCaps products- Name
- ProCaps Labs
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Phone Number
- 800.800.1200
- Web Address
- ProCaps.com
White Mulberry Leaf with Cinnamon by ProCaps: Common Questions
Does White Mulberry Leaf with Cinnamon by ProCaps interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if White Mulberry Leaf with Cinnamon is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind White Mulberry Leaf with Cinnamon’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
White Mulberry
Interacts with 87 drugsWhite mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is generally well tolerated as a food and tea,...
Read the full White Mulberry monograph → Herb & supplement monographCassia Cinnamon
Interacts with 442 drugsCassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...
Read the full Cassia Cinnamon monograph →Sources & How We Checked
White Mulberry Leaf with Cinnamon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
White Mulberry 6 references
- Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. PubMed
- Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. PubMed
- Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. PubMed
- Huh HW, Na YG, Bang KH, et al. Extended intake of mulberry leaf extract delayed metformin elimination via inhibiting the organic cation transporter 2. Pharmaceutics. 2020;12(1):49. PubMed
- Thaipitakwong T, Supasyndh O, Rasmi Y, Aramwit P. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. Complement Ther Med. 2020;49:102292. PubMed
- Thondre PS, Lightowler H, Ahlstrom L, Gallagher A. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond) 2021;18(1):41. PubMed
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
- Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
- Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
- Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
- Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
- Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
- Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
- Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
- Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed
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