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Dietary supplement

Wild Lettuce Leaf Mint Flavor Ingredients & Drug Interactions

by TerraVita

Wild Lettuce Leaf Mint Flavor label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wild Lettuce Leaf Mint Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wild Lettuce Leaf Mint Flavor is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for insomnia and trouble sleeping, anxiety and restlessness, pain relief.Based on those ingredients, 393 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wild Lettuce Leaf Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wild Lettuce Leaf Mint Flavor by TerraVita

Ask about any prescription or over-the-counter medication and we check it for interactions with Wild Lettuce Leaf Mint Flavor by TerraVita — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wild Lettuce Leaf Mint Flavor by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wild lettuce leaf extract in glycerite form (a plant extract made using glycerin as the preserving base). Wild lettuce has traditionally been used for its mild relaxing properties, though effectiveness claims aren't established in our data.

The product also includes glycerin and mint flavor as inactive ingredients for taste and preservation.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: sleep and relaxation support.
  • We looked for evidence on: insomnia, anxiety, muscle tension.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't hold effectiveness ratings for wild lettuce in our data, so we can't speak to how well it actually works for relaxation or any other purpose based on the evidence we have on file.

The evidence, ingredient by ingredient Wild Lettuce

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mature, properly harvested wild lettuce taken by mouth is generally well tolerated. However, large amounts or prematurely harvested wild lettuce can cause serious side effects — dizziness, headache, somnolence (extreme sleepiness), anxiety, pressure in the head, and in rare cases coma or breathing problems.

Contact dermatitis (an allergic rash) is the most common reaction if applied to skin. The product should be avoided during pregnancy due to insufficient safety data.

It's also best avoided while breastfeeding, as there isn't reliable safety information available.

Side effects, ingredient by ingredient Wild Lettuce

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Lettuce.
  • The most serious interaction on file is rated Moderate.
  • For scale: 393 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you use CNS depressants (sedative medications, sleep aids, anxiety drugs, opioids, or other drugs that slow your nervous system) — wild lettuce may add to their effects. Also flag any anticholinergic medications (used for overactive bladder, certain types of IBS, or other conditions).

Search your exact medications below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Wild lettuce is generally well tolerated at normal doses but carries real risks at higher amounts, especially if the plant material isn't properly harvested. It's not appropriate during pregnancy or breastfeeding.

Most importantly, check your exact medications with the tool on this page before starting — interactions with sedating drugs and anticholinergic medications are the main concerns. Talk it over with your doctor or pharmacist about whether this product fits with your health situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wild Lettuce Leaf Mint Flavor, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435232603
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 280675
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wild Lettuce Leaf Mint Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435232603
IngredientAmount% DV
Wild Lettuce Leaf Glycerite Liquid Extract0.13 mL--

Other ingredients: Glycerin, Mint Flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5) Mint flavored

Formulation

Alcohol free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wild Lettuce Leaf Mint Flavor by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wild Lettuce Leaf Mint Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wild Lettuce Leaf Mint Flavor by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Wild Lettuce Leaf Glycerite Liquid Extract

Interacts with
393 drugs
0.13 mL per serving

Wild lettuce is a traditional herb used mainly for sleep, anxiety, and pain, but solid human research supporting these uses is very limited. Because i...

Wild Lettuce Leaf Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Mint Flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wild Lettuce Leaf Mint Flavor by TerraVita Drug Interactions

Want to check YOUR meds against Wild Lettuce Leaf Mint Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
393Drugs
393 Moderate

Ingredients driving the most interactions

Wild Lettuce Leaf Glycerite Liquid Extract 393

Individual Drug Interactions

The ingredients in Wild Lettuce Leaf Mint Flavor interact with 393 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wild Lettuce Leaf Mint Flavor interact with drugs. Each result below shows which ingredient is responsible. Wild Lettuce Leaf Glycerite Liquid Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Wild Lettuce Leaf Mint Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Lettuce Leaf Glycerite Liquid Extract2 drug types · 393 drugs

Anticholinergic Drugs

Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug. If it does, it appears to be in very low amounts. Nevertheless, there have been case reports of individuals consuming large amounts of wild lettuce experiencing anticholinergic-related side effects, such as constipation, dry mouth, dizziness, and sweating. Therefore, if you are already taking a drug with anticholinergic effects, you should be cautious about combining it with wild lettuce as the risk of side effects may be increased.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.

Likelihood Possible Evidence D
Wild Lettuce Leaf Glycerite Liquid Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wild Lettuce Leaf Mint Flavor, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Wild Lettuce Leaf Mint Flavor by TerraVita: Common Questions

Does Wild Lettuce Leaf Mint Flavor by TerraVita interact with any medications?
Yes. Based on its ingredients, Wild Lettuce Leaf Mint Flavor has a known interaction with 393 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wild Lettuce Leaf Mint Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is wild lettuce supposed to do?
Wild lettuce has been traditionally used for its mild relaxing effects, though we don't have effectiveness ratings in our data to confirm how well it actually works for that purpose.
Is this safe to take in large amounts?
No. Large amounts of wild lettuce, or wild lettuce harvested before it's mature, can cause dizziness, headache, extreme sleepiness, and in rare cases much more serious effects like coma or breathing problems. Stick to normal doses, and talk with your pharmacist about what's appropriate for you.
Can I take this while pregnant or breastfeeding?
No. There isn't enough safety data, so it's best avoided during pregnancy. There's also no reliable safety information for breastfeeding, so it should be avoided then too. Talk with your doctor or pharmacist if you have questions about what's safe for you.
Can wild lettuce cause a rash?
Yes, if you apply it to your skin. Contact dermatitis (an allergic rash) is the most common skin reaction, especially in people who are sensitive to it.
What's in this product besides the active ingredient?
The product also contains glycerin (a liquid preservative) and mint flavor to make it taste better. These are inactive ingredients used to preserve the extract and improve the taste.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wild Lettuce Leaf Mint Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wild Lettuce Leaf Mint Flavor label
Go deeper

The Full Monographs Behind Wild Lettuce Leaf Mint Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Lettuce

Interacts with 393 drugs

Wild lettuce is a traditional herb used mainly for sleep, anxiety, and pain, but solid human research supporting these uses is very limited. Because its safety is not well studied, it should...

Read the full Wild Lettuce monograph →
Sources

Sources & How We Checked

Wild Lettuce Leaf Mint Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Lettuce 5 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Besharat S, Besharat M, Jabbari A. Wild lettuce (Lactuca virosa) toxicity. BMJ Case Rep. 2009;2009. pii: bcr06.2008.0134.
  5. Mullins ME, Horowitz BZ. The case of the salad shooters: intravenous injection of wild lettuce extract. Vet Hum Toxicol. 1998;40(5):290-1.

See these in context on the Wild Lettuce monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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