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Dietary supplement

Wintergreen Ingredients & Drug Interactions

by Herbal Terra

Wintergreen label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wintergreen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Wintergreen is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for muscle and joint pain (topical), arthritis discomfort, headaches.Based on those ingredients, 37 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are wildcrafted Wintergreen (Gaultheria procumbens) dried leaf liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wintergreen by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Wintergreen by Herbal Terra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wintergreen by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: a liquid extract of wildcrafted wintergreen leaf (Gaultheria procumbens). The extract is prepared using menstruum as the extraction medium.

Wintergreen leaf has been used traditionally for pain and inflammation, though the evidence supporting those uses is not well established in our data.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Wintergreen product and its label doesn't state a use — see Wintergreen's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have reliable evidence to rate wintergreen for back pain, muscle soreness, or joint pain. The data we hold shows insufficient evidence for these common uses — that doesn't mean it doesn't work, only that the clinical support isn't established in what we have on file.

The evidence, ingredient by ingredient Wintergreen

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Topically, wintergreen oil appears generally well tolerated, but the pure essential oil is extremely toxic if swallowed. Orally, wintergreen leaf seems generally well tolerated, but wintergreen oil carries risk of salicylate poisoning — symptoms include headache, ringing in the ears (tinnitus), and confusion.

Topically, wintergreen oil can cause contact dermatitis (skin irritation or allergic reaction), and you should never cover it with an occlusive dressing, as that increases absorption of toxic amounts of methyl salicylate. For pregnancy, safety data is not on file.

For lactation, the safety data advises against use — talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Wintergreen

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wintergreen.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 37 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take warfarin (Coumadin) or aspirin. Wintergreen contains methyl salicylate, which can increase bleeding risk with warfarin and add to salicylate toxicity with aspirin — both are Major or Moderate concerns depending on how much you use and for how long.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Wintergreen liquid extract carries real risks with blood thinners and aspirin. If you take warfarin or aspirin regularly, check with your pharmacist before using this product.

Even topical application can be absorbed enough to cause problems. Pregnant women and those breastfeeding should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wintergreen, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 0606595858882
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 235323
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wintergreen by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
0606595858882
IngredientAmount% DV
wildcrafted Wintergreen (Gaultheria procumbens) dried leaf liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Origin of plant material: India.

Manufactured in the USA in an FDA registered facility

Alcohol free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Alcohol-free liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Gaultheria procumbens

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wintergreen by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wintergreen label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wintergreen by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Wildcrafted Wintergreen (Gaultheria procumbens) dried leaf liquid extract

Interacts with
37 drugs
970 mg per serving

Wintergreen is a low-growing North American plant whose oil is rich in methyl salicylate, an aspirin-like compound used in topical pain rubs. While it...

Wildcrafted Wintergreen (Gaultheria procumbens) dried leaf liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wintergreen by Herbal Terra Drug Interactions

Want to check YOUR meds against Wintergreen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
37Drugs
2 Major 35 Moderate

Ingredients driving the most interactions

wildcrafted Wintergreen (Gaultheria procumbens) dried leaf liquid extract 37

Individual Drug Interactions

The ingredients in Wintergreen interact with 37 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wintergreen interact with drugs. Each result below shows which ingredient is responsible. wildcrafted Wintergreen (Gaultheria procumbens) dried leaf liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Wintergreen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wildcrafted Wintergreen (Gaultheria procumbens) dried leaf liquid extract2 drug types · 37 drugs

Warfarin (Coumadin)

Using wintergreen oil topically might increase the effects and adverse effects of warfarin.
Several case reports show that concomitant use of topical wintergreen oil-containing products and warfarin can increase INR and bleeding risk due to systemic absorption of the methyl salicylate contained in wintergreen oil. Topical analgesic gels, lotions, creams, ointments, liniments, and sprays can contain up to 55% methyl salicylate.

Likelihood Probable Evidence D
Aspirin

Using wintergreen oil topically in large amounts, with occlusive dressings, or for prolonged periods of time might increase the risk of additive salicylate toxicity when used with aspirin.
Wintergreen oil contains methyl salicylate. Topical analgesic gels, lotions, creams, ointments, liniments, and sprays can contain up to 55% methyl salicylate.

Likelihood Probable Evidence D
wildcrafted Wintergreen (Gaultheria procumbens) dried leaf liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wintergreen, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Wintergreen by Herbal Terra: Common Questions

Does Wintergreen by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Wintergreen has a known interaction with 37 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wintergreen contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I take warfarin or aspirin?
Not without checking with your pharmacist first. Wintergreen contains methyl salicylate, which can increase warfarin's blood-thinning effects and raise bleeding risk, and can add to salicylate toxicity when combined with aspirin. These are serious interactions — check your exact medications before starting.
Is wintergreen oil safe to swallow?
No. The pure essential oil is extremely toxic if swallowed and can cause salicylate poisoning, with symptoms like headache, ringing in the ears, and confusion. Wintergreen leaf itself seems generally well tolerated orally, but the oil should only be used topically under proper guidance.
Will wintergreen help my back or joint pain?
We don't have reliable evidence to say whether it works for back pain, muscle soreness, or joint pain. The clinical support for these uses isn't established in our data — talk with your pharmacist about whether it's worth trying for your situation.
Can I use this while pregnant or breastfeeding?
Safety data for pregnancy is not on file — we don't know enough either way. For breastfeeding, the data advises against use. Talk with your doctor or pharmacist about whether this product is right for you in either situation.
What should I watch out for if I use it topically?
Don't cover the area with a bandage or occlusive dressing — that traps the oil and allows too much to be absorbed through your skin, which can cause toxic effects. Wintergreen oil can also cause contact dermatitis (skin irritation or allergic reaction). If you take warfarin or aspirin, check with your pharmacist first even for topical use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wintergreen is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wintergreen label
Go deeper

The Full Monographs Behind Wintergreen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wintergreen

Interacts with 37 drugs

Wintergreen is a low-growing North American plant whose oil is rich in methyl salicylate, an aspirin-like compound used in topical pain rubs. While it may help ease minor muscle and joint pa...

Read the full Wintergreen monograph →
Sources

Sources & How We Checked

Wintergreen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wintergreen 7 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Gossel TA, Bricker JD. Principles of Clinical Toxicology. New York, NY:Raven Press, 1994.
  4. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  5. Chan TY. Potential dangers from topical preparations containing methyl salicylate. Hum Exp Toxicol 1996;15:747-50.
  6. Joss JD, LeBlond RF. Potentiation of warfarin anticoagulation associated with topical methyl salicylate. Ann Pharmacother 2000;34:729-33. PubMed
  7. Franceschi J, Darrigade AS, Jegou MH, Milpied B. First report of allergic contact dermatitis caused by Gaultheria procumbens (wintergreen) essential oil. Contact Dermatitis 2022;87(2):193-195.

See these in context on the Wintergreen monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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