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Dietary supplement

Xin Yi Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Xin Yi is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 351 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Magnolia liliiflora Flower Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Xin Yi by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Xin Yi contains one active ingredient: magnolia liliiflora flower extract (dried form). This is a traditional botanical extract used in some herbal preparations.

The liquid formula also contains alcohol, water, and glycerin as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Magnolia's overall clinical evidence instead.

Moderate

Some clinical evidence supports Magnolia for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Gingivitis — rated "Possibly Effective" (Natural Medicines).

The data we hold shows magnolia is possibly effective for gingivitis. For other uses—hay fever, anxiety, and dental plaque—the evidence isn't established well enough to rate it.

If you're considering Xin Yi for one of those purposes, talk with your pharmacist about what the current research actually supports.

The evidence, ingredient by ingredient Magnolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, magnolia seems to be generally well tolerated in most adults short-term, though human safety data is limited. We don't have reliable safety information for pregnancy or breastfeeding, so those situations call for a conversation with your doctor or pharmacist before use.

A small number of trial participants in studies of combination products containing magnolia reported side effects like sexual dysfunction, tremor, numbness around the mouth, fatigue, and headache—though it's unclear whether magnolia itself was responsible. Topical magnolia can cause contact dermatitis in some people.

Side effects, ingredient by ingredient Magnolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Magnolia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 351 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you use this product, double-check if you take any blood thinners or antiplatelet drugs (like warfarin, aspirin, clopidogrel)—magnolia may increase bleeding risk. Also check if you're on CNS depressants (benzodiazepines, sleep aids, opioids), since combined sedative effects are possible.

Use the medication checker on this page to verify your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Xin Yi might be worth considering if you're exploring botanical options for gingivitis and you don't take blood thinners or sedating medications. If you're on any prescription drugs—especially anticoagulants, antiplatelets, or CNS depressants—check with your pharmacist first.

Pregnant or breastfeeding? Talk to your doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Xin Yi, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7238360777314
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 325529
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Xin Yi by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7238360777314
IngredientAmount% DV
Magnolia liliiflora Flower Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

Organic alcohol

No artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Magnolia lilliflora

Organic alcohol

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

General Statements

Organic raw material.

See for yourself

Xin Yi by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Xin Yi by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Magnolia liliiflora Flower Extract, Dry

Interacts with
351 drugs
983 mg per serving

Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human r...

Magnolia liliiflora Flower Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Xin Yi by Herbal Terra Drug Interactions

Want to check YOUR meds against Xin Yi?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
351Drugs
351 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Xin Yi with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Magnolia liliiflora Flower Extract, Dry2 drug types · 351 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Xin Yi, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Xin Yi by Herbal Terra: Common Questions

Does Xin Yi by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Xin Yi has a known interaction with 351 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Xin Yi contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Xin Yi while pregnant or breastfeeding?
We don't have reliable safety data for either. Some sources suggest magnolia might affect the uterus. Talk with your doctor or pharmacist before using it in pregnancy or while breastfeeding—they can help you decide what's right for your situation.
What's magnolia extract actually used for?
The data shows it's possibly effective for gingivitis. For hay fever, anxiety, and dental plaque, the evidence isn't strong enough to say whether it works. Your pharmacist can discuss whether it fits your health goals.
What side effects might I notice?
When taken by mouth, magnolia is generally well tolerated. A few trial participants reported sexual dysfunction, tremor, numbness, fatigue, and headache, though we don't know if magnolia caused them. If you apply it to skin, watch for contact dermatitis.
Is this product safe long-term?
The safety data for long-term use is limited. We know it seems okay short-term for many adults, but there isn't enough human research to promise anything beyond that. If you plan to use it regularly, check in with your pharmacist.
What's in this liquid besides the magnolia extract?
It contains alcohol, water, and glycerin. If you need to avoid alcohol, this form might not be right for you—ask your pharmacist about alternatives.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Xin Yi is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Xin Yi label
Sources

Sources & How We Checked

Xin Yi's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Magnolia 9 references
  1. Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
  2. Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
  3. Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
  4. Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
  5. Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
  6. Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
  7. Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
  8. Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
  9. Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.

See these in context on the Magnolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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