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Dietary supplement

Xin Yi Non-Alcohol Ingredients & Drug Interactions

by Hawaii Pharm

Xin Yi Non-Alcohol label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Xin Yi Non-Alcohol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Xin Yi Non-Alcohol is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 351 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wild harvested Xin Yi extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Xin Yi Non-Alcohol by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Xin Yi Non-Alcohol by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Xin Yi Non-Alcohol by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product has one active ingredient: wild harvested Xin Yi extract, which comes from magnolia. The rest is vegetable palm glycerin and Hawaiian artesian water — both are inactive ingredients that help deliver the extract in liquid form.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Anxiety and stress relief.
  • We looked for evidence on: Anxiety, Stress, Sleep quality, Nervous tension, Emotional balance.
  • The closest evidence on file: Magnolia is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Magnolia is rated "Insufficient Reliable Evidence To Rate" for Stress.

The evidence for magnolia is mixed and limited. It's possibly effective for gingivitis (gum disease), but for allergic rhinitis (hay fever), anxiety, and dental plaque, there isn't enough reliable evidence to rate whether it works.

If you're considering this for gum health, talk with your dentist about whether it fits into your routine.

The evidence, ingredient by ingredient Magnolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Magnolia taken by mouth is generally well tolerated in most adults short-term, though human safety data is limited. The main topical side effect reported is contact dermatitis (skin irritation).

In clinical trials of combination products containing magnolia, a small number of participants reported sexual dysfunction, shaking hands, numbness around the mouth, fatigue, and headache — though it's unclear whether magnolia itself caused these or another ingredient did. Safety data during pregnancy advises against use, and there isn't enough data to know about breastfeeding, so talk with your doctor or pharmacist if you're pregnant or nursing.

Side effects, ingredient by ingredient Magnolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Magnolia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 351 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your medications against our tool below, especially if you take CNS depressants (sedatives, sleep aids, anti-anxiety drugs, strong pain relievers) or blood thinners and antiplatelet drugs (like warfarin, aspirin, or clopidogrel). Both carry Moderate interaction risk with magnolia.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Xin Yi Non-Alcohol may be worth considering if you're looking at natural options for gum health, but the evidence is limited. If you take any blood thinners, sleep aids, sedatives, or other CNS depressants, check with your pharmacist first — this product can interact with them.

The safety data for pregnancy and breastfeeding isn't complete, so get personalized advice if that applies to you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Xin Yi Non-Alcohol, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 0748399933102
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 23, 2020
DSLD ID 238506
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Xin Yi Non-Alcohol by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
30 Drop(s)
UPC/BARCODE
0748399933102
IngredientAmount% DV
wild harvested Xin Yi extract0 NP--

Other ingredients: Vegetable Palm Glycerin, crystal clear artesian Hawaiian Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Non-Alcohol Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no gluten, artificial colors, pesticides, preservatives, heavy metals. Non GMO.

Super concentrated liquid herbal extract Dry herb/menstruum ratio: 1:3

Contains no alcohol

Description: We meticulously produced this extract according to precise standards where each herbs are individually extracted according to their distinct characteristic to ensure a broad spectrum of therapeutic plant compounds. We use a classic maceration extraction method in combination with ultrasonic extraction, so that the vitamins, minerals, alkaloids, flavonoids and other active constituents of the herbs are maintained.

Non GMO Gluten free

Manufactured in an FDA registered facility. Ultra Sonic

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops in juice, water, tea or as desired up to four times per day.

Precautions

Warnings: Keep out of the reach of children.

Not to be used during pregnancy.

Do not use if you are allergic to any ingredients.

Consult a physician before using if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Refrigerate after opening.

Formula

(Magnolia lilliflora)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Xin Yi Non-Alcohol by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Xin Yi Non-Alcohol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Xin Yi Non-Alcohol by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.

Wild harvested Xin Yi extract

Interacts with
351 drugs
0 NP per serving

Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human r...

Wild harvested Xin Yi extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Crystal clear artesian Hawaiian Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Xin Yi Non-Alcohol by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Xin Yi Non-Alcohol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
351Drugs
351 Moderate

Ingredients driving the most interactions

wild harvested Xin Yi extract 351

Individual Drug Interactions

The ingredients in Xin Yi Non-Alcohol interact with 351 drugs. Click any drug to see the details.

1 of the 1 ingredient in Xin Yi Non-Alcohol interact with drugs. Each result below shows which ingredient is responsible. wild harvested Xin Yi extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Xin Yi Non-Alcohol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wild harvested Xin Yi extract2 drug types · 351 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.

Likelihood Possible Evidence D
wild harvested Xin Yi extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Xin Yi Non-Alcohol, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Pharmacist Counseling Corner

Xin Yi Non-Alcohol by Hawaii Pharm: Common Questions

Does Xin Yi Non-Alcohol by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Xin Yi Non-Alcohol has a known interaction with 351 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Xin Yi Non-Alcohol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin?
Magnolia in this product may interact with blood thinners and could increase your bleeding risk. Don't start it without talking to your pharmacist or doctor first — they can assess your individual situation.
Is Xin Yi safe to take during pregnancy?
No. The safety data advises against use during pregnancy, and some sources caution that it may affect the uterus. If you're pregnant or planning to be, talk with your doctor before taking this.
What is Xin Yi extract actually used for?
Magnolia extract is possibly effective for gingivitis (gum disease), but the evidence for other uses — like allergic rhinitis, anxiety, and dental plaque — isn't strong enough to rate yet.
What side effects might I experience?
When taken by mouth, magnolia is generally well tolerated. The most commonly reported issue is contact dermatitis if applied to skin. In clinical trials of combination products, a small number of people reported fatigue, headache, sexual dysfunction, or numbness, though it's unclear if magnolia caused these.
Does this product contain any fillers or unnecessary ingredients?
It has two inactive ingredients: vegetable palm glycerin and Hawaiian artesian water. These help deliver the magnolia extract in liquid form — they're standard in liquid supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Xin Yi Non-Alcohol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Xin Yi Non-Alcohol label
Go deeper

The Full Monographs Behind Xin Yi Non-Alcohol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Magnolia

Interacts with 351 drugs

Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human research is still limited, so we can't be...

Read the full Magnolia monograph →
Sources

Sources & How We Checked

Xin Yi Non-Alcohol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Magnolia 9 references
  1. Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
  2. Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
  3. Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
  4. Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
  5. Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
  6. Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
  7. Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
  8. Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
  9. Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.

See these in context on the Magnolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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