Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Xtra-Cell Zepatix Ingredients & Drug Interactions

by Douglas Laboratories

Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Xtra-Cell Zepatix is a dietary supplement by Douglas Laboratories with 3 active ingredients. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Porcine Liver Aqueous Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Xtra-Cell Zepatix by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Xtra-Cell Zepatix contains three active ingredients, all derived from porcine (pig) tissue: Porcine Thymus Aqueous Extract, Porcine Liver Aqueous Extract, and Porcine Mesenchyme Aqueous Extract 125X. These are concentrated water extracts meant to support immune and tissue function.

There are no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The facts on file address liver extract's use in chronic fatigue syndrome (rated possibly ineffective) and hepatitis C (rated insufficient evidence). We don't hold effectiveness data for the thymus extract or mesenchyme extract in this product, so we can't tell you how well they work for any condition.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been formally reported with liver extract, but a thorough safety evaluation hasn't been done. The bigger concern is source quality: liver extract comes from raw animal liver at slaughterhouses, which carries a small risk of contamination from sick animals.

There's also a theoretical risk of bovine spongiform encephalopathy (BSE, a fatal brain disease in cattle) if the source country has reported cases — though no human infections from contaminated liver extract have been documented. Liver extract can deliver very high levels of vitamin A and iron, so it's not suitable in pregnancy without medical approval.

We don't have pregnancy or breastfeeding safety data for the thymus or mesenchyme extracts.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or iron-containing medications or supplements, talk to us before you start. The liver extract in this product can theoretically reduce warfarin's blood-thinning effect and may increase your total iron intake.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

If you take warfarin or iron supplements, check with your pharmacist before starting this product — the liver extract may interfere with how they work. The product is generally low-risk for healthy adults using normal amounts, but source-quality concerns and high nutrient loads mean it's worth discussing with your doctor first, especially if you're pregnant, breastfeeding, or have an iron-storage disorder.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Xtra-Cell Zepatix, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 310539025079
Net contents 24 Bottle(s); 7.2 fl. Oz.; 216 mL
Market status On market
Date entered into DSLD Jun 25, 2012
DSLD ID 10408
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Xtra-Cell Zepatix by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.3 fl. Oz.
Maximum serving Sizes:
0.3 fl. Oz.
Servings per container
24
UPC/BARCODE
310539025079
IngredientAmount% DV
Porcine Thymus Aqueous Extract0.1 fl. Oz.--
Porcine Liver Aqueous Extract0.07 fl. Oz.--
Porcine Mesenchyme Aqueous Extract 125X0.13 fl. Oz.--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Storage

KEEP FROZEN

Formula

With Highly Concentrated 125X Mesenchyme Extract

General Statements

Contains: 24 Bottles of 0.3 fl. oz (9 ml) Individually Sealed

Suggested/Recommended/Usage/Directions

FOR ORAL USE ONLY! Suggested Usage: As a dietary supplement, take 1 bottle of Xtra-Cell(R) Zepatix per day. Follow the instructions included in this box or as directed by your healthcare professional.

Precautions

KEEP OUT OF REACH OF CHILDREN

Warning: Do not use if security seal is broken or missing. This product may not be suitable for children 12 years of age or younger, pregnant or nursing women, individuals taking immunosuppressants or persons allergic to pork products. Consult a healthcare professional before use.

General

Formula #99462-24XC

See for yourself

Xtra-Cell Zepatix by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Xtra-Cell Zepatix by Douglas Laboratories

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.3 fl. Oz. Dosage formLiquid Servings per container24 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Porcine Thymus Aqueous Extract

0.1 fl. Oz. per serving

Porcine Liver Aqueous Extract

Interacts with
3 drugs
0.07 fl. Oz. per serving Form: Mesenchyme 125X

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Porcine Liver Aqueous Extract monograph & interactions

Porcine Mesenchyme Aqueous Extract 125X

0.13 fl. Oz. per serving

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Xtra-Cell Zepatix by Douglas Laboratories Drug Interactions

Want to check YOUR meds against Xtra-Cell Zepatix?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Xtra-Cell Zepatix with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Porcine Liver Aqueous Extract2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Xtra-Cell Zepatix, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Xtra-Cell Zepatix by Douglas Laboratories: Common Questions

Does Xtra-Cell Zepatix by Douglas Laboratories interact with any medications?
Yes. Based on its ingredients, Xtra-Cell Zepatix has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Xtra-Cell Zepatix contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Not without checking first. The liver extract can contain vitamin K, which may reduce how well warfarin works. We need to look at your dose and INR to be sure it's safe — don't start on your own.
Is this safe to take while pregnant?
The liver extract can deliver very high vitamin A levels, which may harm a developing baby. The safety data for the other two ingredients isn't on file. Talk to your doctor before using if you're pregnant or trying to conceive.
What are these porcine extracts supposed to do?
They're meant to support immune and tissue function. We don't have reliable evidence data for how well they work in any specific condition.
What if I also take iron supplements?
The liver extract contains heme iron on its own, so adding iron supplements could push your total iron intake too high, especially over time. Let us know if you're taking iron — we can help you figure out if it's safe to combine them.
Are there fillers or other inactive ingredients in this?
No — the product lists no inactive ingredients, so you're getting just the three active extracts in liquid form.
Where does the liver extract come from, and is it safe?
It comes from pigs at slaughterhouses. There's a small risk of contamination from sick animals, and if sourced from certain countries, a theoretical risk of BSE contamination — though no human infections have been reported. Ask the manufacturer which country it's from to be sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Xtra-Cell Zepatix is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Xtra-Cell Zepatix label
Sources

Sources & How We Checked

Xtra-Cell Zepatix's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring