Anakinra

Generic name: Pronounced as (an a kin' ra)
Brand names
  • Kineret®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 06/15/2021

Anakinra is used alone or in combination with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who were not helped by other disease-modifying antirheumatic drugs (DMARDs). Anakinra is also used to treat neonatal-onset multisystem inflammatory disease (NOMID; a disorder that causes inflammation and damages the nervous system, skin, and joints) in adults and children. Anakinra is also used to treat deficiency of interleukin-1 receptor antagonist (DIRA; a disorder in which the body attacks its own tissues causing inflammation and damages bones, nervous system, skin, lungs, liver, and joints) in adults and children. Anakinra is in a class of medications called interleukin antagonists. It works by blocking the activity of interleukin, a substance in the body that causes inflammation.

Anakinra injection comes as a solution to inject subcutaneously (under the skin). It is usually given once a day. However, when anakinra is given to treat neonatal-onset multisystem inflammatory disease, it may given once or twice daily. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use anakinra injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

You will receive your first subcutaneous dose of anakinra injection in your doctor's office. After that, your doctor may decide that you or your caregiver can give the injections at home. Your doctor will show you or the person who will be giving the medication how to inject it. You or the person who will be injecting the medication should also read the written instructions for use that come with the medication. Be sure to ask your doctor or pharmacist if you have any questions about how to inject the medication.

Anakinra injection comes in prefilled glass syringes. There are 7 syringes in each box, one for each day of the week. Use each syringe only once. Even if there is still some solution left in the syringe after you inject, do not inject again. Dispose of used syringes in a puncture-resistant container. Talk to your doctor or pharmacist about how to dispose of the puncture-resistant container.

Remove the medication from the refrigerator 30 minutes before you are ready to inject the medication. Place it on a flat surface and allow it to reach room temperature. When removing the prefilled syringe from the box, do not shake the syringe or remove the cap covering the needle.

Check the prefilled syringe to be sure that the expiration date printed on the package has not passed. Look closely at the liquid in the syringe. The liquid should be clear and should not be cloudy or discolored or contain large particles. Call your pharmacist if there are any problems with the package or the syringe and do not inject the medication.

You may inject anakinra in the front of the middle thighs or in your lower stomach below your navel except for the 2-inch (5-centimeter) area around the navel. If someone else is giving you the injection, it can be injected into the outer area of your upper arms, or outer and upper areas of buttocks. Choose a different spot to inject the medication every day. Do not inject into an area where your skin is red, bruised, tender, hard, or scaly, or where you have scars or stretch marks. Do not inject close to a vein you can see under the skin.

Anakinra injection may help control your symptoms, but it will not cure your condition. Continue to use anakinra injection even if you feel well. Do not stop using anakinra injection without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking anakinra,

  • tell your doctor and pharmacist if you are allergic to anakinra, proteins made from bacterial cells (E. coli), latex, or any other medications.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: abatacept (Orencia) certolizumab (Cimzia), etanercept (Enbrel), golimumab (Simponi), and infliximab (Remicade. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with anakinra, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have or ever had asthma or kidney disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using anakinra, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are using anakinra.

  • you should know that anakinra injection may decrease your ability to fight infection from bacteria, viruses, and fungi and increase the risk that you will get a serious infection. Tell your doctor if you often get any type of infection or if you have or think you may have any type of infection now. This includes minor infections (such as open cuts or sores), infections that come and go (such as herpes or cold sores), and chronic infections that do not go away. If you experience any of the following symptoms during or shortly after your treatment with anakinra injection, call your doctor immediately: fever, sweats, or chills; sore throat; cough; warm, red, or painful skin or sores on your body; frequent, urgent, or painful urination; or other signs of infection.

  • you should know that using anakinra injection increases the risk that you will develop tuberculosis (TB; a serious lung infection), especially if you are already infected with tuberculosis but do not have any symptoms of the disease. Tell your doctor if you have or have ever had TB, if you have lived in a country where TB is common, or if you have been around someone who has TB. Your doctor will perform a skin test to see if you have an inactive TB infection. If necessary, your doctor will give you medication to treat this infection before you start using anakinra injection. If you have any of the following symptoms of TB, or if you develop any of these symptoms during your treatment, call your doctor immediately: cough, coughing up blood or mucus, weakness or tiredness, weight loss, loss of appetite, chills, fever, or night sweats.

  • do not have any vaccinations without talking to your doctor.

Unless your doctor tells you otherwise, continue your normal diet.

Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.

  • Anakinra may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • redness, swelling, bruising, itching, or pain at the site of injection

    • headache

    • nausea

    • vomiting

    • diarrhea

    • runny nose

    • stomach pain

    • joint pain

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately or get emergency medical treatment:

    • rash

    • itching

    • hives

    • swelling of the lips, tongue, mouth, or face

    • dizziness

    • fainting

    • difficulty breathing

    • wheezing

    • sweating

    • fast or racing heart beat

  • Anakinra may increase the risk of developing certain types of cancer including lymphoma (cancer that begins in the cells that fight infection) and skin cancer. People who have had severe rheumatoid arthritis for a long time may have a greater than normal risk of developing these cancers even if they do not use anakinra. Talk to your doctor about the risks of using this medication.

  • Anakinra may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep syringes and injection supplies out of the reach of children. Store anakinra syringes in the refrigerator. Do not freeze. Protect from light.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before and during treatment to check your body's response to anakinra.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Repaglinide Repaglinide The metabolism of Repaglinide can be increased when combined with Anakinra.
Montelukast Montelukast The metabolism of Montelukast can be increased when combined with Anakinra.
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Anakinra is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Delavirdine can be increased when combined with Anakinra.
Nevirapine Nevirapine The metabolism of Nevirapine can be increased when combined with Anakinra.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be increased when combined with Anakinra.
Dolasetron Dolasetron The metabolism of Dolasetron can be increased when combined with Anakinra.
Aminophylline Aminophylline The metabolism of Aminophylline can be increased when combined with Anakinra.
Anagrelide Anagrelide The metabolism of Anagrelide can be increased when combined with Anakinra.
Candesartan Candesartan The metabolism of Candesartan can be increased when combined with Anakinra.
Cilostazol Cilostazol The metabolism of Cilostazol can be increased when combined with Anakinra.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be increased when combined with Anakinra.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Erythromycin can be increased when combined with Anakinra.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be increased when combined with Anakinra.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be increased when combined with Anakinra.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Anakinra is combined with Mycophenolic acid.
Paregoric Paregoric The metabolism of Morphine can be increased when combined with Anakinra.
Penbutolol Penbutolol The metabolism of Acebutolol can be increased when combined with Anakinra.
Prednisone Prednisone The risk or severity of adverse effects can be increased when Anakinra is combined with Prednisone.
Ranitidine Ranitidine The metabolism of Ranitidine can be increased when combined with Anakinra.
Tacrolimus Tacrolimus Tacrolimus may increase the immunosuppressive activities of Anakinra.
Tizanidine Tizanidine The metabolism of Tizanidine can be increased when combined with Anakinra.
Triamcinolone Triamcinolone The metabolism of Triamcinolone can be increased when combined with Anakinra.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Anakinra.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be increased when combined with Anakinra.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Interferon beta-1b.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Interferon gamma-1b.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be increased when combined with Anakinra.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Methylprednisolone.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be increased when combined with Anakinra.
Metronidazole Injection Metronidazole Injection The metabolism of Metronidazole can be increased when combined with Anakinra.
Morphine Injection Morphine Injection The metabolism of Morphine can be increased when combined with Anakinra.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be increased when combined with Anakinra.
Altretamine Altretamine The metabolism of Amphetamine can be increased when combined with Anakinra.
Cyclosporine Cyclosporine Anakinra may increase the immunosuppressive activities of Cyclosporine.
Ondansetron Ondansetron The metabolism of Ondansetron can be increased when combined with Anakinra.
Torsemide Torsemide The metabolism of Torasemide can be increased when combined with Anakinra.
Olanzapine Olanzapine The metabolism of Olanzapine can be increased when combined with Anakinra.
Alosetron Alosetron The metabolism of Alosetron can be increased when combined with Anakinra.
Dofetilide Dofetilide The metabolism of Dofetilide can be increased when combined with Anakinra.
Hydroxychloroquine Hydroxychloroquine The metabolism of Hydroxychloroquine can be increased when combined with Anakinra.
Meloxicam Meloxicam The metabolism of Meloxicam can be increased when combined with Anakinra.
Pantoprazole Pantoprazole The metabolism of Pantoprazole can be increased when combined with Anakinra.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Anakinra is combined with Temozolomide.
Zaleplon Zaleplon The metabolism of Zaleplon can be increased when combined with Anakinra.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Anakinra is combined with Linezolid.
Trimipramine Trimipramine The metabolism of Trimipramine can be increased when combined with Anakinra.
Etanercept Injection Etanercept Injection The risk or severity of adverse effects can be increased when Etanercept is combined with Anakinra.
Tenofovir Tenofovir The metabolism of Tenofovir can be increased when combined with Anakinra.
Sirolimus Sirolimus The metabolism of Sirolimus can be increased when combined with Anakinra.
Dutasteride Dutasteride The metabolism of Dutasteride can be increased when combined with Anakinra.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Anakinra is combined with Epirubicin.
Eplerenone Eplerenone The metabolism of Eplerenone can be increased when combined with Anakinra.
Escitalopram Escitalopram The metabolism of Escitalopram can be increased when combined with Anakinra.
Zonisamide Zonisamide The metabolism of Zonisamide can be increased when combined with Anakinra.
Adalimumab Injection Adalimumab Injection The risk or severity of adverse effects can be increased when Adalimumab is combined with Anakinra.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be increased when combined with Anakinra.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be increased when combined with Anakinra.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Glatiramer.
Atazanavir Atazanavir The metabolism of Atazanavir can be increased when combined with Anakinra.
Almotriptan Almotriptan The metabolism of Almotriptan can be increased when combined with Anakinra.
Eletriptan Eletriptan The metabolism of Eletriptan can be increased when combined with Anakinra.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be increased when combined with Anakinra.
Vardenafil Vardenafil The metabolism of Vardenafil can be increased when combined with Anakinra.
Aprepitant Aprepitant The metabolism of Aprepitant can be increased when combined with Anakinra.
Tegaserod Tegaserod The metabolism of Tegaserod can be increased when combined with Anakinra.
Tadalafil Tadalafil The metabolism of Tadalafil can be increased when combined with Anakinra.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be increased when combined with Anakinra.
Progesterone Progesterone The metabolism of Progesterone can be increased when combined with Anakinra.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be increased when combined with Anakinra.
Infliximab Injection Infliximab Injection The risk or severity of adverse effects can be increased when Infliximab is combined with Anakinra.
Protriptyline Protriptyline The metabolism of Protriptyline can be increased when combined with Anakinra.
Duloxetine Duloxetine The metabolism of Duloxetine can be increased when combined with Anakinra.
Norethindrone Norethindrone The metabolism of Norethisterone can be increased when combined with Anakinra.
Bosentan Bosentan The metabolism of Bosentan can be increased when combined with Anakinra.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be increased when combined with Anakinra.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Natalizumab.
Erlotinib Erlotinib The metabolism of Erlotinib can be increased when combined with Anakinra.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be increased when combined with Anakinra.
Solifenacin Solifenacin The metabolism of Solifenacin can be increased when combined with Anakinra.
Voriconazole Voriconazole The metabolism of Voriconazole can be increased when combined with Anakinra.
Dextroamphetamine Dextroamphetamine The metabolism of Amphetamine can be increased when combined with Anakinra.
Entecavir Entecavir The metabolism of Entecavir can be increased when combined with Anakinra.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Anakinra.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Anakinra.
Ramelteon Ramelteon The metabolism of Ramelteon can be increased when combined with Anakinra.
Darifenacin Darifenacin The metabolism of Darifenacin can be increased when combined with Anakinra.
Fentanyl Fentanyl The metabolism of Fentanyl can be increased when combined with Anakinra.
Tipranavir Tipranavir The metabolism of Tipranavir can be increased when combined with Anakinra.
Felbamate Felbamate The metabolism of Felbamate can be increased when combined with Anakinra.
Ranolazine Ranolazine The metabolism of Ranolazine can be increased when combined with Anakinra.
Abatacept Injection Abatacept Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Abatacept.
Rasagiline Rasagiline The metabolism of Rasagiline can be increased when combined with Anakinra.
Imatinib Imatinib The metabolism of Imatinib can be increased when combined with Anakinra.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be increased when combined with Anakinra.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Bevacizumab.
Gefitinib Gefitinib The metabolism of Gefitinib can be increased when combined with Anakinra.
Paliperidone Paliperidone The metabolism of Paliperidone can be increased when combined with Anakinra.
Bortezomib Bortezomib The metabolism of Bortezomib can be increased when combined with Anakinra.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Clofarabine.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Anakinra.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Anakinra.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Anakinra.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Anakinra.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Oxaliplatin.
Primaquine Primaquine The metabolism of Primaquine can be increased when combined with Anakinra.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Rituximab.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be increased when combined with Anakinra.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be increased when combined with Anakinra.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Anakinra is combined with Vorinostat.
Sorafenib Sorafenib The metabolism of Sorafenib can be increased when combined with Anakinra.
Sunitinib Sunitinib The metabolism of Sunitinib can be increased when combined with Anakinra.
Dronabinol Dronabinol The metabolism of Dronabinol can be increased when combined with Anakinra.
Lapatinib Lapatinib The metabolism of Lapatinib can be increased when combined with Anakinra.
Dasatinib Dasatinib The metabolism of Dasatinib can be increased when combined with Anakinra.
Mexiletine Mexiletine The metabolism of Mexiletine can be increased when combined with Anakinra.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Azacitidine.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be increased when combined with Anakinra.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Nelarabine.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Anakinra is combined with Lenalidomide.
Nilotinib Nilotinib The metabolism of Nilotinib can be increased when combined with Anakinra.
Bexarotene Bexarotene The metabolism of Bexarotene can be increased when combined with Anakinra.
Budesonide Budesonide The risk or severity of adverse effects can be increased when Anakinra is combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Decitabine.
Etravirine Etravirine The metabolism of Etravirine can be increased when combined with Anakinra.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Mitoxantrone.
Cevimeline Cevimeline The metabolism of Cevimeline can be increased when combined with Anakinra.
Nebivolol Nebivolol The metabolism of Nebivolol can be increased when combined with Anakinra.
Tretinoin Tretinoin The metabolism of Tretinoin can be increased when combined with Anakinra.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Anakinra.
Flecainide Flecainide The metabolism of Flecainide can be increased when combined with Anakinra.
Certolizumab Injection Certolizumab Injection The risk or severity of adverse effects can be increased when Certolizumab pegol is combined with Anakinra.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Anakinra.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Anakinra.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Anakinra is combined with Estramustine.
Praziquantel Praziquantel The metabolism of Praziquantel can be increased when combined with Anakinra.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Anakinra is combined with Alemtuzumab.
Rufinamide Rufinamide The metabolism of Rufinamide can be increased when combined with Anakinra.
Midazolam Midazolam The metabolism of Midazolam can be increased when combined with Anakinra.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Dexrazoxane.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be increased when combined with Anakinra.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Ibritumomab tiuxetan.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be increased when combined with Anakinra.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be increased when combined with Anakinra.
Betaxolol Betaxolol The metabolism of Betaxolol can be increased when combined with Anakinra.
Iloperidone Iloperidone The metabolism of Iloperidone can be increased when combined with Anakinra.
Prasugrel Prasugrel The metabolism of Prasugrel can be increased when combined with Anakinra.
Lacosamide Lacosamide The metabolism of Lacosamide can be increased when combined with Anakinra.
Everolimus Everolimus The metabolism of Everolimus can be increased when combined with Anakinra.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be increased when combined with Anakinra.
Dronedarone Dronedarone The metabolism of Dronedarone can be increased when combined with Anakinra.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Pralatrexate.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be increased when combined with Anakinra.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be increased when combined with Anakinra.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Anakinra.
Tapentadol Tapentadol The metabolism of Tapentadol can be increased when combined with Anakinra.
Topotecan Topotecan The risk or severity of adverse effects can be increased when Anakinra is combined with Topotecan.
Golimumab Injection Golimumab Injection The risk or severity of adverse effects can be increased when Golimumab is combined with Anakinra.
Pazopanib Pazopanib The metabolism of Pazopanib can be increased when combined with Anakinra.
Asenapine Asenapine The metabolism of Asenapine can be increased when combined with Anakinra.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be increased when combined with Anakinra.
Albendazole Albendazole The metabolism of Albendazole can be increased when combined with Anakinra.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Anakinra.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be increased when combined with Anakinra.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Anakinra.
Tocilizumab Injection Tocilizumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Tocilizumab.
Fingolimod Fingolimod Anakinra may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Anakinra.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be increased when combined with Anakinra.
Vilazodone Vilazodone The metabolism of Vilazodone can be increased when combined with Anakinra.
Denileukin Diftitox Injection Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Aldesleukin.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Anakinra.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Belimumab.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Anakinra.
Roflumilast Roflumilast Anakinra may increase the immunosuppressive activities of Roflumilast.
Linagliptin Linagliptin The metabolism of Linagliptin can be increased when combined with Anakinra.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Anakinra.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be increased when combined with Anakinra.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Anakinra.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Anakinra.
Vandetanib Vandetanib The metabolism of Vandetanib can be increased when combined with Anakinra.
Clobazam Clobazam The metabolism of Clobazam can be increased when combined with Anakinra.
Vemurafenib Vemurafenib The metabolism of Vemurafenib can be increased when combined with Anakinra.
Vismodegib Vismodegib The metabolism of Vismodegib can be increased when combined with Anakinra.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Belatacept.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be increased when combined with Anakinra.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Basiliximab.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Anakinra.
Crizotinib Crizotinib The metabolism of Crizotinib can be increased when combined with Anakinra.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Melphalan.
Cabergoline Cabergoline The metabolism of Cabergoline can be increased when combined with Anakinra.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be increased when combined with Anakinra.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Eculizumab.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Carfilzomib.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be increased when combined with Anakinra.
Mirabegron Mirabegron The metabolism of Mirabegron can be increased when combined with Anakinra.
Regorafenib Regorafenib The metabolism of Regorafenib can be increased when combined with Anakinra.
Bosutinib Bosutinib The metabolism of Bosutinib can be increased when combined with Anakinra.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Corticotropin.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Anakinra is combined with Teriflunomide.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be increased when combined with Anakinra.
Tofacitinib Tofacitinib The risk or severity of adverse effects can be increased when Anakinra is combined with Tofacitinib.
Alogliptin Alogliptin The metabolism of Alogliptin can be increased when combined with Anakinra.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Anakinra is combined with Dimethyl fumarate.
Ponatinib Ponatinib The metabolism of Ponatinib can be increased when combined with Anakinra.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Anakinra.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Anakinra.
Apixaban Apixaban The metabolism of Apixaban can be increased when combined with Anakinra.
Dabrafenib Dabrafenib The metabolism of Dabrafenib can be increased when combined with Anakinra.
Ospemifene Ospemifene The metabolism of Ospemifene can be increased when combined with Anakinra.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Anakinra.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be increased when combined with Anakinra.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Anakinra.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be increased when combined with Anakinra.
Lomitapide Lomitapide The metabolism of Lomitapide can be increased when combined with Anakinra.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be increased when combined with Anakinra.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Obinutuzumab.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be increased when combined with Anakinra.
Apremilast Apremilast The therapeutic efficacy of Apremilast can be decreased when used in combination with Anakinra.
Ceritinib Ceritinib The metabolism of Ceritinib can be increased when combined with Anakinra.
Siltuximab Injection Siltuximab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Siltuximab.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Belinostat.
Idelalisib Idelalisib The metabolism of Idelalisib can be increased when combined with Anakinra.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be increased when combined with Anakinra.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be increased when combined with Anakinra.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be increased when combined with Anakinra.
Suvorexant Suvorexant The metabolism of Suvorexant can be increased when combined with Anakinra.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be increased when combined with Anakinra.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Blinatumomab.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be increased when combined with Anakinra.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be increased when combined with Anakinra.
Riociguat Riociguat The metabolism of Riociguat can be increased when combined with Anakinra.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be increased when combined with Anakinra.
Nintedanib Nintedanib The metabolism of Nintedanib can be increased when combined with Anakinra.
Secukinumab Injection Secukinumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be increased when combined with Anakinra.
Palbociclib Palbociclib The metabolism of Palbociclib can be increased when combined with Anakinra.
Panobinostat Panobinostat The metabolism of Panobinostat can be increased when combined with Anakinra.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The metabolism of Haloperidol can be increased when combined with Anakinra.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Anakinra.
Prednisolone Prednisolone The risk or severity of adverse effects can be increased when Anakinra is combined with Prednisolone.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be increased when combined with Anakinra.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be increased when combined with Anakinra.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be increased when combined with Anakinra.
Cariprazine Cariprazine The metabolism of Cariprazine can be increased when combined with Anakinra.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be increased when combined with Anakinra.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Mepolizumab.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Anakinra.
Osimertinib Osimertinib The metabolism of Osimertinib can be increased when combined with Anakinra.
Alectinib Alectinib The metabolism of Alectinib can be increased when combined with Anakinra.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Anakinra.
Lesinurad Lesinurad The metabolism of Lesinurad can be increased when combined with Anakinra.
Dexamethasone Injection Dexamethasone Injection The metabolism of Dexamethasone can be increased when combined with Anakinra.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Ixekizumab.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be increased when combined with Anakinra.
Venetoclax Venetoclax The metabolism of Venetoclax can be increased when combined with Anakinra.
Cobicistat Cobicistat The metabolism of Cobicistat can be increased when combined with Anakinra.
Selexipag Selexipag The metabolism of Selexipag can be increased when combined with Anakinra.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be increased when combined with Anakinra.
Rucaparib Rucaparib The metabolism of Rucaparib can be increased when combined with Anakinra.
Ribociclib Ribociclib The metabolism of Ribociclib can be increased when combined with Anakinra.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Brigatinib can be increased when combined with Anakinra.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be increased when combined with Anakinra.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be increased when combined with Anakinra.
Valbenazine Valbenazine The metabolism of Valbenazine can be increased when combined with Anakinra.
Deflazacort Deflazacort The risk or severity of adverse effects can be increased when Anakinra is combined with Deflazacort.
Ocrelizumab Injection Ocrelizumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Ocrelizumab.
Sarilumab Injection Sarilumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Midostaurin can be increased when combined with Anakinra.
Neratinib Neratinib The metabolism of Neratinib can be increased when combined with Anakinra.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Guselkumab.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Anakinra.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Anakinra.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Anakinra.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be increased when combined with Anakinra.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Anakinra.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Gemtuzumab ozogamicin.
Letermovir Letermovir The metabolism of Letermovir can be increased when combined with Anakinra.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be increased when combined with Anakinra.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be increased when combined with Anakinra.
Apalutamide Apalutamide The metabolism of Apalutamide can be increased when combined with Anakinra.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Anakinra is combined with Penicillamine.
Baricitinib Baricitinib The metabolism of Baricitinib can be increased when combined with Anakinra.
Lofexidine Lofexidine The metabolism of Lofexidine can be increased when combined with Anakinra.
Eliglustat Eliglustat The metabolism of Eliglustat can be increased when combined with Anakinra.
Encorafenib Encorafenib The metabolism of Encorafenib can be increased when combined with Anakinra.
Binimetinib Binimetinib The metabolism of Binimetinib can be increased when combined with Anakinra.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be increased when combined with Anakinra.
Elagolix Elagolix The metabolism of Elagolix can be increased when combined with Anakinra.
Doravirine Doravirine The metabolism of Doravirine can be increased when combined with Anakinra.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be increased when combined with Anakinra.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be increased when combined with Anakinra.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be increased when combined with Anakinra.
Duvelisib Duvelisib The metabolism of Duvelisib can be increased when combined with Anakinra.
Stiripentol Stiripentol The metabolism of Stiripentol can be increased when combined with Anakinra.
Gilteritinib Gilteritinib The metabolism of Gilteritinib can be increased when combined with Anakinra.
Glasdegib Glasdegib The metabolism of Glasdegib can be increased when combined with Anakinra.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be increased when combined with Anakinra.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Anakinra.
Prucalopride Prucalopride The metabolism of Prucalopride can be increased when combined with Anakinra.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be increased when combined with Anakinra.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be increased when combined with Anakinra.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be increased when combined with Anakinra.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be increased when combined with Anakinra.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Risankizumab.
Alpelisib Alpelisib The metabolism of Alpelisib can be increased when combined with Anakinra.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Anakinra is combined with Cladribine.
Triclabendazole Triclabendazole The metabolism of Triclabendazole can be increased when combined with Anakinra.
Entrectinib Entrectinib The metabolism of Entrectinib can be increased when combined with Anakinra.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be increased when combined with Anakinra.
Istradefylline Istradefylline The metabolism of Istradefylline can be increased when combined with Anakinra.
Pitolisant Pitolisant The metabolism of Pitolisant can be increased when combined with Anakinra.
Fedratinib Fedratinib The metabolism of Fedratinib can be increased when combined with Anakinra.
Lefamulin Lefamulin The metabolism of Lefamulin can be increased when combined with Anakinra.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be increased when combined with Anakinra.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be increased when combined with Anakinra.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Anakinra.
Voxelotor Voxelotor The metabolism of Voxelotor can be increased when combined with Anakinra.
Avapritinib Avapritinib The metabolism of Avapritinib can be increased when combined with Anakinra.
Tazemetostat Tazemetostat The metabolism of Tazemetostat can be increased when combined with Anakinra.
Cenobamate Cenobamate The metabolism of Cenobamate can be increased when combined with Anakinra.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Anakinra is combined with Ozanimod.
Selumetinib Selumetinib The metabolism of Selumetinib can be increased when combined with Anakinra.
Tucatinib Tucatinib The metabolism of Tucatinib can be increased when combined with Anakinra.
Lemborexant Lemborexant The metabolism of Lemborexant can be increased when combined with Anakinra.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Anakinra.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Anakinra.
Indomethacin Indomethacin The metabolism of Indomethacin can be increased when combined with Anakinra.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be increased when combined with Anakinra.
Naproxen Naproxen The metabolism of Naproxen can be increased when combined with Anakinra.
Trazodone Trazodone The metabolism of Trazodone can be increased when combined with Anakinra.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Anakinra is combined with Hydroxyurea.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Anakinra is combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be increased when combined with Anakinra.
Methotrexate Injection Methotrexate Injection The metabolism of Methotrexate can be increased when combined with Anakinra.
Primidone Primidone The metabolism of Primidone can be increased when combined with Anakinra.
Methsuximide Methsuximide The metabolism of Methsuximide can be increased when combined with Anakinra.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Anakinra.
Diazepam Diazepam The metabolism of Diazepam can be increased when combined with Anakinra.
Flurazepam Flurazepam The metabolism of Flurazepam can be increased when combined with Anakinra.
Lorazepam Lorazepam The metabolism of Lorazepam can be increased when combined with Anakinra.
Carmustine Carmustine The metabolism of Carmustine can be increased when combined with Anakinra.
Codeine Codeine The metabolism of Codeine can be increased when combined with Anakinra.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Anakinra is combined with Procarbazine.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Anakinra is combined with Tioguanine.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be increased when combined with Anakinra.
Thioridazine Thioridazine The metabolism of Thioridazine can be increased when combined with Anakinra.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Anakinra.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Anakinra is combined with Bleomycin.
Dapsone Dapsone The metabolism of Dapsone can be increased when combined with Anakinra.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be increased when combined with Anakinra.
Oxycodone Oxycodone The metabolism of Oxycodone can be increased when combined with Anakinra.
Methadone Methadone The metabolism of Methadone can be increased when combined with Anakinra.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be increased when combined with Anakinra.
Benztropine Benztropine The metabolism of Benzatropine can be increased when combined with Anakinra.
Maprotiline Maprotiline The metabolism of Maprotiline can be increased when combined with Anakinra.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be increased when combined with Anakinra.
Perphenazine Perphenazine The metabolism of Perphenazine can be increased when combined with Anakinra.
Azathioprine Azathioprine The metabolism of Azathioprine can be increased when combined with Anakinra.
Phentermine Phentermine The metabolism of Phentermine can be increased when combined with Anakinra.
Amoxapine Amoxapine The metabolism of Amoxapine can be increased when combined with Anakinra.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Anakinra is combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The metabolism of Hydrocortisone can be increased when combined with Anakinra.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Anakinra is combined with Lomustine.
Doxorubicin Doxorubicin The metabolism of Doxorubicin can be increased when combined with Anakinra.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Anakinra is combined with Cytarabine.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Anakinra is combined with Mechlorethamine.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Anakinra is combined with Dactinomycin.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be increased when combined with Anakinra.
Clonidine Clonidine The metabolism of Clonidine can be increased when combined with Anakinra.
Warfarin Warfarin The metabolism of Warfarin can be increased when combined with Anakinra.
Loperamide Loperamide The metabolism of Loperamide can be increased when combined with Anakinra.
Promethazine Promethazine The metabolism of Promethazine can be increased when combined with Anakinra.
Daunorubicin Daunorubicin The risk or severity of adverse effects can be increased when Anakinra is combined with Daunorubicin.
Chloroquine Chloroquine The metabolism of Chloroquine can be increased when combined with Anakinra.
Quinine Quinine The metabolism of Quinine can be increased when combined with Anakinra.
Ethosuximide Ethosuximide The metabolism of Ethosuximide can be increased when combined with Anakinra.
Triamterene Triamterene The metabolism of Triamterene can be increased when combined with Anakinra.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Anakinra.
Desipramine Desipramine The metabolism of Desipramine can be increased when combined with Anakinra.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be increased when combined with Anakinra.
Imipramine Imipramine The metabolism of Imipramine can be increased when combined with Anakinra.
Quinidine Quinidine The metabolism of Quinidine can be increased when combined with Anakinra.
Procainamide Procainamide The metabolism of Procainamide can be increased when combined with Anakinra.
Disopyramide Disopyramide The metabolism of Disopyramide can be increased when combined with Anakinra.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be increased when combined with Anakinra.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Anakinra.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Anakinra is combined with Mitomycin.
Methimazole Methimazole The risk or severity of adverse effects can be increased when Anakinra is combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Anakinra is combined with Propylthiouracil.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be increased when combined with Anakinra.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be increased when combined with Anakinra.
Tolazamide Tolazamide The metabolism of Tolazamide can be increased when combined with Anakinra.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be increased when combined with Anakinra.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be increased when combined with Anakinra.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be increased when combined with Anakinra.
Brompheniramine Brompheniramine The metabolism of Brompheniramine can be increased when combined with Anakinra.
Meclizine Meclizine The metabolism of Meclizine can be increased when combined with Anakinra.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be increased when combined with Anakinra.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be increased when combined with Anakinra.
Disulfiram Disulfiram The metabolism of Disulfiram can be increased when combined with Anakinra.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Propranolol can be increased when combined with Anakinra.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be increased when combined with Anakinra.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Anakinra is combined with Mercaptopurine.
Nadolol Nadolol The metabolism of Nadolol can be increased when combined with Anakinra.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be increased when combined with Anakinra.
Colchicine Colchicine The risk or severity of adverse effects can be increased when Anakinra is combined with Colchicine.
Cephalexin Cephalexin The metabolism of Cephalexin can be increased when combined with Anakinra.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be increased when combined with Anakinra.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Anakinra.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Anakinra.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be increased when combined with Anakinra.
Vinblastine Vinblastine The metabolism of Vinblastine can be increased when combined with Anakinra.
Metoprolol Metoprolol The metabolism of Metoprolol can be increased when combined with Anakinra.
Hydroxyzine Hydroxyzine The metabolism of Hydroxyzine can be increased when combined with Anakinra.
Thiothixene Thiothixene The metabolism of Thiothixene can be increased when combined with Anakinra.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be increased when combined with Anakinra.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Anakinra is combined with Chlorambucil.
Alprazolam Alprazolam The metabolism of Alprazolam can be increased when combined with Anakinra.
Triazolam Triazolam The metabolism of Triazolam can be increased when combined with Anakinra.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be increased when combined with Anakinra.
Diltiazem Diltiazem The metabolism of Diltiazem can be increased when combined with Anakinra.
Nifedipine Nifedipine The metabolism of Nifedipine can be increased when combined with Anakinra.
Timolol Timolol The metabolism of Timolol can be increased when combined with Anakinra.
Verapamil Verapamil The metabolism of Verapamil can be increased when combined with Anakinra.
Atenolol Atenolol The metabolism of Atenolol can be increased when combined with Anakinra.
Pindolol Pindolol The metabolism of Pindolol can be increased when combined with Anakinra.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Cisplatin.
Piroxicam Piroxicam The metabolism of Piroxicam can be increased when combined with Anakinra.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Anakinra is combined with Streptozocin.
Etoposide Etoposide The metabolism of Etoposide can be increased when combined with Anakinra.
Glyburide Glyburide The metabolism of Glyburide can be increased when combined with Anakinra.
Glipizide Glipizide The metabolism of Glipizide can be increased when combined with Anakinra.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be increased when combined with Anakinra.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be increased when combined with Anakinra.
Labetalol Labetalol The metabolism of Labetalol can be increased when combined with Anakinra.
Guanabenz Guanabenz The metabolism of Guanabenz can be increased when combined with Anakinra.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Anakinra.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be increased when combined with Anakinra.
Amiodarone Amiodarone The metabolism of Amiodarone can be increased when combined with Anakinra.
Buspirone Buspirone The metabolism of Buspirone can be increased when combined with Anakinra.
Lovastatin Lovastatin The metabolism of Lovastatin can be increased when combined with Anakinra.
Diclofenac Diclofenac The metabolism of Diclofenac can be increased when combined with Anakinra.
Fluoxetine Fluoxetine The metabolism of Fluoxetine can be increased when combined with Anakinra.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Interferon alfa-2b.
Clozapine Clozapine The metabolism of Clozapine can be increased when combined with Anakinra.
Idarubicin Idarubicin The metabolism of Idarubicin can be increased when combined with Anakinra.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Fludarabine.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Pentostatin.
Clarithromycin Clarithromycin The metabolism of Clarithromycin can be increased when combined with Anakinra.
Etodolac Etodolac The metabolism of Etodolac can be increased when combined with Anakinra.
Felodipine Felodipine The metabolism of Felodipine can be increased when combined with Anakinra.
Nabumetone Nabumetone The metabolism of Nabumetone can be increased when combined with Anakinra.
Simvastatin Simvastatin The metabolism of Simvastatin can be increased when combined with Anakinra.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be increased when combined with Anakinra.
Sotalol Sotalol The metabolism of Sotalol can be increased when combined with Anakinra.
Zolpidem Zolpidem The metabolism of Zolpidem can be increased when combined with Anakinra.
Doxazosin Doxazosin The metabolism of Doxazosin can be increased when combined with Anakinra.
Omeprazole Omeprazole The metabolism of Omeprazole can be increased when combined with Anakinra.
Cisapride Cisapride The metabolism of Cisapride can be increased when combined with Anakinra.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be increased when combined with Anakinra.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be increased when combined with Anakinra.
Famciclovir Famciclovir The metabolism of Famciclovir can be increased when combined with Anakinra.
Fluvoxamine Fluvoxamine The metabolism of Fluvoxamine can be increased when combined with Anakinra.
Nefazodone Nefazodone The metabolism of Nefazodone can be increased when combined with Anakinra.
Losartan Losartan The metabolism of Losartan can be increased when combined with Anakinra.
Tramadol Tramadol The metabolism of Tramadol can be increased when combined with Anakinra.
Vinorelbine Injection Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Anakinra.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Carboplatin.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be increased when combined with Anakinra.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Anakinra.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Pegaspargase.
Nicardipine Nicardipine The metabolism of Nicardipine can be increased when combined with Anakinra.
Bupropion Bupropion The metabolism of Bupropion can be increased when combined with Anakinra.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be increased when combined with Anakinra.
Saquinavir Saquinavir The metabolism of Saquinavir can be increased when combined with Anakinra.
Nisoldipine Nisoldipine The metabolism of Nisoldipine can be increased when combined with Anakinra.
Riluzole Riluzole The metabolism of Riluzole can be increased when combined with Anakinra.
Glimepiride Glimepiride The metabolism of Glimepiride can be increased when combined with Anakinra.
Anastrozole Anastrozole The metabolism of Anastrozole can be increased when combined with Anakinra.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Anakinra is combined with Gemcitabine.
Indinavir Indinavir The metabolism of Indinavir can be increased when combined with Anakinra.
Ritonavir Ritonavir The metabolism of Ritonavir can be increased when combined with Anakinra.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Anakinra.
Clomipramine Clomipramine The metabolism of Clomipramine can be increased when combined with Anakinra.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be increased when combined with Anakinra.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be increased when combined with Anakinra.
Zileuton Zileuton The metabolism of Zileuton can be increased when combined with Anakinra.
Valsartan Valsartan The metabolism of Valsartan can be increased when combined with Anakinra.
Donepezil Donepezil The metabolism of Donepezil can be increased when combined with Anakinra.
Azithromycin Azithromycin The metabolism of Azithromycin can be increased when combined with Anakinra.
Carvedilol Carvedilol The metabolism of Carvedilol can be increased when combined with Anakinra.
Flutamide Flutamide The metabolism of Flutamide can be increased when combined with Anakinra.
Selegiline Selegiline The metabolism of Selegiline can be increased when combined with Anakinra.
Bicalutamide Bicalutamide The metabolism of Bicalutamide can be increased when combined with Anakinra.
Sertraline Sertraline The metabolism of Sertraline can be increased when combined with Anakinra.
Propafenone Propafenone The metabolism of Propafenone can be increased when combined with Anakinra.
Letrozole Letrozole The metabolism of Letrozole can be increased when combined with Anakinra.
Irbesartan Irbesartan The metabolism of Irbesartan can be increased when combined with Anakinra.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be increased when combined with Anakinra.
Ropinirole Ropinirole The metabolism of Ropinirole can be increased when combined with Anakinra.
Finasteride Finasteride The metabolism of Finasteride can be increased when combined with Anakinra.
Quetiapine Quetiapine The metabolism of Quetiapine can be increased when combined with Anakinra.
Paroxetine Paroxetine The metabolism of Paroxetine can be increased when combined with Anakinra.
Citalopram Citalopram The metabolism of Citalopram can be increased when combined with Anakinra.
Capecitabine Capecitabine The metabolism of Capecitabine can be increased when combined with Anakinra.
Efavirenz Efavirenz The metabolism of Efavirenz can be increased when combined with Anakinra.
Sildenafil Sildenafil The metabolism of Sildenafil can be increased when combined with Anakinra.
Pioglitazone Pioglitazone The metabolism of Pioglitazone can be increased when combined with Anakinra.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Anakinra.
Celecoxib Celecoxib The metabolism of Celecoxib can be increased when combined with Anakinra.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be increased when combined with Anakinra.
Tolterodine Tolterodine The metabolism of Tolterodine can be increased when combined with Anakinra.
Thalidomide Thalidomide The metabolism of Thalidomide can be increased when combined with Anakinra.
Nateglinide Nateglinide The metabolism of Nateglinide can be increased when combined with Anakinra.
Galantamine Galantamine The metabolism of Galantamine can be increased when combined with Anakinra.
Rabeprazole Rabeprazole The metabolism of Rabeprazole can be increased when combined with Anakinra.
Terbinafine Terbinafine The metabolism of Terbinafine can be increased when combined with Anakinra.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists