Lusutrombopag
Generic name: Pronounced as (loo" soo trom' boe pag)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 09/15/2018
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
Why is this medication prescribed?
Lusutrombopag is used treat thrombocytopenia (a low number of platelets [type of blood cell needed for blood clotting]) in patients with chronic (ongoing) liver disease who are scheduled to have a medical or dental procedure to help prevent bleeding complications. Lusutrombopag is in a class of medications called thrombopoietin (TPO) receptor agonists. It works by causing the body to produce more platelets.
How should this medicine be used?
Lusutrombopag comes as a tablet to take by mouth. It is usually taken with or without food once a day for 7 days, starting 8 to 14 days before the scheduled procedure. Take lusutrombopag at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lusutrombopag exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking lusutrombopag,
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tell your doctor and pharmacist if you are allergic to lusutrombopag, any other medications, or any of the ingredients in lusutrombopag tablets. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
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tell your doctor if you have or have ever had a blood clot or a genetic condition that could lead to blood clots.
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tell your doctor if you are pregnant, or plan to become pregnant. If you become pregnant while taking lusutrombopag, call your doctor.
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tell your doctor if you are breastfeeding. Your doctor will probably tell you not to breastfeed during your treatment and for 4 weeks after your final dose.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it on the same day. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Lusutrombopag may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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headache
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Some side effects can be serious. If you experience any of these symptoms call your doctor immediately:
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swollen, painful, red, or tender leg
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shortness of breath, cough, chest pain, fast heartbeat
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stomach pain or tenderness
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Lusutrombopag may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
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swollen, painful, red or tender leg
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shortness of breath, cough, chest pain, fast heartbeat
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stomach pain or tenderness
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to lusutrombopag.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The serum concentration of Lusutrombopag can be increased when it is combined with Erythromycin. |
Paregoric | Paregoric The serum concentration of Lusutrombopag can be increased when it is combined with Morphine. |
Reserpine | Reserpine The serum concentration of Lusutrombopag can be increased when it is combined with Reserpine. |
Tacrolimus | Tacrolimus The serum concentration of Lusutrombopag can be increased when it is combined with Tacrolimus. |
Fluconazole Injection | Fluconazole Injection The serum concentration of Lusutrombopag can be increased when it is combined with Fluconazole. |
Morphine Injection | Morphine Injection The serum concentration of Lusutrombopag can be increased when it is combined with Morphine. |
Cyclosporine | Cyclosporine Cyclosporine may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Pantoprazole | Pantoprazole Pantoprazole may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Telmisartan | Telmisartan Telmisartan may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Trimipramine | Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Lusutrombopag. |
Tenofovir | Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Lusutrombopag. |
Sirolimus | Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Lusutrombopag. |
Zonisamide | Zonisamide The serum concentration of Lusutrombopag can be increased when it is combined with Zonisamide. |
Vardenafil | Vardenafil The serum concentration of Lusutrombopag can be increased when it is combined with Vardenafil. |
Tegaserod | Tegaserod The serum concentration of Lusutrombopag can be increased when it is combined with Tegaserod. |
Progesterone | Progesterone Progesterone may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Erlotinib | Erlotinib Erlotinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Tipranavir | Tipranavir The serum concentration of Lusutrombopag can be increased when it is combined with Tipranavir. |
Ranolazine | Ranolazine The serum concentration of Lusutrombopag can be increased when it is combined with Ranolazine. |
Imatinib | Imatinib Imatinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Sitagliptin | Sitagliptin The serum concentration of Lusutrombopag can be increased when it is combined with Sitagliptin. |
Gefitinib | Gefitinib Gefitinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Paliperidone | Paliperidone The serum concentration of Lusutrombopag can be increased when it is combined with Paliperidone. |
Bortezomib | Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Lusutrombopag. |
Posaconazole | Posaconazole The serum concentration of Lusutrombopag can be increased when it is combined with Posaconazole. |
Sorafenib | Sorafenib The serum concentration of Lusutrombopag can be increased when it is combined with Sorafenib. |
Sunitinib | Sunitinib Sunitinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Dronabinol | Dronabinol Dronabinol may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Lapatinib | Lapatinib The serum concentration of Lusutrombopag can be increased when it is combined with Lapatinib. |
Dasatinib | Dasatinib Dasatinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Temsirolimus | Temsirolimus The serum concentration of Lusutrombopag can be increased when it is combined with Temsirolimus. |
Nilotinib | Nilotinib The serum concentration of Lusutrombopag can be increased when it is combined with Nilotinib. |
Toremifene | Toremifene The serum concentration of Lusutrombopag can be increased when it is combined with Toremifene. |
Bendamustine Injection | Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Lusutrombopag. |
Silodosin | Silodosin The serum concentration of Lusutrombopag can be increased when it is combined with Silodosin. |
Eltrombopag | Eltrombopag Eltrombopag may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Everolimus | Everolimus The serum concentration of Lusutrombopag can be increased when it is combined with Everolimus. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The serum concentration of Lusutrombopag can be increased when it is combined with Tolvaptan. |
Dronedarone | Dronedarone The serum concentration of Lusutrombopag can be increased when it is combined with Dronedarone. |
Romidepsin Injection | Romidepsin Injection The serum concentration of Lusutrombopag can be increased when it is combined with Romidepsin. |
Topotecan | Topotecan The serum concentration of Topotecan can be increased when it is combined with Lusutrombopag. |
Pazopanib | Pazopanib The serum concentration of Lusutrombopag can be increased when it is combined with Pazopanib. |
Cabazitaxel Injection | Cabazitaxel Injection Cabazitaxel may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Linagliptin | Linagliptin The serum concentration of Lusutrombopag can be increased when it is combined with Linagliptin. |
Rilpivirine | Rilpivirine Rilpivirine may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Telaprevir | Telaprevir The serum concentration of Glecaprevir can be increased when it is combined with Lusutrombopag. |
Rivaroxaban | Rivaroxaban The serum concentration of Lusutrombopag can be increased when it is combined with Rivaroxaban. |
Ticagrelor | Ticagrelor The serum concentration of Lusutrombopag can be increased when it is combined with Ticagrelor. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Lusutrombopag. |
Vandetanib | Vandetanib Vandetanib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Clobazam | Clobazam The serum concentration of Lusutrombopag can be increased when it is combined with Clobazam. |
Vemurafenib | Vemurafenib The serum concentration of Lusutrombopag can be increased when it is combined with Vemurafenib. |
Vismodegib | Vismodegib Vismodegib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Ivacaftor | Ivacaftor The serum concentration of Lusutrombopag can be increased when it is combined with Ivacaftor. |
Axitinib | Axitinib The serum concentration of Axitinib can be increased when it is combined with Lusutrombopag. |
Crizotinib | Crizotinib The serum concentration of Lusutrombopag can be increased when it is combined with Crizotinib. |
Cabergoline | Cabergoline The serum concentration of Cabergoline can be increased when it is combined with Lusutrombopag. |
Ambrisentan | Ambrisentan The serum concentration of Lusutrombopag can be increased when it is combined with Ambrisentan. |
Carfilzomib Injection | Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Lusutrombopag. |
Enzalutamide | Enzalutamide The serum concentration of Lusutrombopag can be increased when it is combined with Enzalutamide. |
Mirabegron | Mirabegron The serum concentration of Lusutrombopag can be increased when it is combined with Mirabegron. |
Regorafenib | Regorafenib The serum concentration of Lusutrombopag can be increased when it is combined with Regorafenib. |
Bosutinib | Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Lusutrombopag. |
Teriflunomide | Teriflunomide Teriflunomide may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Ponatinib | Ponatinib The serum concentration of Lusutrombopag can be increased when it is combined with Ponatinib. |
Pomalidomide | Pomalidomide The serum concentration of Lusutrombopag can be increased when it is combined with Pomalidomide. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The serum concentration of Lusutrombopag can be increased when it is combined with Trastuzumab emtansine. |
Apixaban | Apixaban The serum concentration of Lusutrombopag can be increased when it is combined with Apixaban. |
Canagliflozin | Canagliflozin The serum concentration of Lusutrombopag can be increased when it is combined with Canagliflozin. |
Dabrafenib | Dabrafenib Dabrafenib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Dolutegravir | Dolutegravir The serum concentration of Lusutrombopag can be increased when it is combined with Dolutegravir. |
Afatinib | Afatinib Afatinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Lomitapide | Lomitapide The serum concentration of Lusutrombopag can be increased when it is combined with Lomitapide. |
Simeprevir | Simeprevir The serum concentration of Lusutrombopag can be increased when it is combined with Simeprevir. |
Sofosbuvir | Sofosbuvir The serum concentration of Lusutrombopag can be increased when it is combined with Sofosbuvir. |
Ceritinib | Ceritinib The serum concentration of Lusutrombopag can be increased when it is combined with Ceritinib. |
Belinostat Injection | Belinostat Injection The serum concentration of Lusutrombopag can be increased when it is combined with Belinostat. |
Idelalisib | Idelalisib The serum concentration of Lusutrombopag can be increased when it is combined with Idelalisib. |
Vorapaxar | Vorapaxar The serum concentration of Lusutrombopag can be increased when it is combined with Vorapaxar. |
Suvorexant | Suvorexant The serum concentration of Lusutrombopag can be increased when it is combined with Suvorexant. |
Edoxaban | Edoxaban The serum concentration of Lusutrombopag can be increased when it is combined with Edoxaban. |
Olaparib | Olaparib Olaparib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Nintedanib | Nintedanib The serum concentration of Lusutrombopag can be increased when it is combined with Nintedanib. |
Palbociclib | Palbociclib Palbociclib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Lenvatinib | Lenvatinib The serum concentration of Lusutrombopag can be increased when it is combined with Lenvatinib. |
Panobinostat | Panobinostat The serum concentration of Lusutrombopag can be increased when it is combined with Panobinostat. |
Isavuconazonium Injection | Isavuconazonium Injection The serum concentration of Lusutrombopag can be increased when it is combined with Isavuconazonium. |
Flibanserin | Flibanserin The serum concentration of Lusutrombopag can be increased when it is combined with Flibanserin. |
Rolapitant | Rolapitant The serum concentration of Lusutrombopag can be increased when it is combined with Rolapitant. |
Daclatasvir | Daclatasvir The serum concentration of Lusutrombopag can be increased when it is combined with Daclatasvir. |
Cobimetinib | Cobimetinib The serum concentration of Lusutrombopag can be increased when it is combined with Cobimetinib. |
Osimertinib | Osimertinib The serum concentration of Lusutrombopag can be increased when it is combined with Osimertinib. |
Alectinib | Alectinib Alectinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Dexamethasone Injection | Dexamethasone Injection Dexamethasone may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Venetoclax | Venetoclax The serum concentration of Lusutrombopag can be increased when it is combined with Venetoclax. |
Cobicistat | Cobicistat The serum concentration of Lusutrombopag can be increased when it is combined with Cobicistat. |
Selexipag | Selexipag The serum concentration of Lusutrombopag can be increased when it is combined with Selexipag. |
Rucaparib | Rucaparib The serum concentration of Lusutrombopag can be increased when it is combined with Rucaparib. |
Brigatinib | Brigatinib Brigatinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Safinamide | Safinamide Safinamide may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Neratinib | Neratinib The serum concentration of Lusutrombopag can be increased when it is combined with Neratinib. |
Enasidenib | Enasidenib The serum concentration of Lusutrombopag can be increased when it is combined with Enasidenib. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Lusutrombopag can be increased when it is combined with Inotuzumab ozogamicin. |
Copanlisib Injection | Copanlisib Injection The serum concentration of Lusutrombopag can be increased when it is combined with Copanlisib. |
Abemaciclib | Abemaciclib Abemaciclib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Betrixaban | Betrixaban The serum concentration of Lusutrombopag can be increased when it is combined with Betrixaban. |
Letermovir | Letermovir Letermovir may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Ertugliflozin | Ertugliflozin The serum concentration of Lusutrombopag can be increased when it is combined with Ertugliflozin. |
Buprenorphine Injection | Buprenorphine Injection Buprenorphine may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Apalutamide | Apalutamide The serum concentration of Lusutrombopag can be decreased when it is combined with Apalutamide. |
Fostamatinib | Fostamatinib Fostamatinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Avatrombopag | Avatrombopag Avatrombopag may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Baricitinib | Baricitinib Baricitinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Eliglustat | Eliglustat The serum concentration of Lusutrombopag can be increased when it is combined with Eliglustat. |
Binimetinib | Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Lusutrombopag. |
Ivosidenib | Ivosidenib The serum concentration of Ivosidenib can be increased when it is combined with Lusutrombopag. |
Elagolix | Elagolix The serum concentration of Elagolix can be increased when it is combined with Lusutrombopag. |
Cannabidiol | Cannabidiol Cannabidiol may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Dacomitinib | Dacomitinib Dacomitinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Duvelisib | Duvelisib The serum concentration of Lusutrombopag can be increased when it is combined with Duvelisib. |
Omadacycline | Omadacycline The serum concentration of Lusutrombopag can be increased when it is combined with Omadacycline. |
Sarecycline | Sarecycline The serum concentration of Lusutrombopag can be increased when it is combined with Sarecycline. |
Talazoparib | Talazoparib The serum concentration of Lusutrombopag can be increased when it is combined with Talazoparib. |
Gilteritinib | Gilteritinib Gilteritinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Glasdegib | Glasdegib Glasdegib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Larotrectinib | Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Lusutrombopag. |
Rifamycin | Rifamycin The serum concentration of Lusutrombopag can be increased when it is combined with Rifamycin. |
Erdafitinib | Erdafitinib The serum concentration of Lusutrombopag can be increased when it is combined with Erdafitinib. |
Darolutamide | Darolutamide The serum concentration of Lusutrombopag can be increased when it is combined with Darolutamide. |
Entrectinib | Entrectinib The serum concentration of Lusutrombopag can be increased when it is combined with Entrectinib. |
Istradefylline | Istradefylline Istradefylline may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Pitolisant | Pitolisant The serum concentration of Lusutrombopag can be increased when it is combined with Pitolisant. |
Fedratinib | Fedratinib Fedratinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Lefamulin | Lefamulin The serum concentration of Lusutrombopag can be increased when it is combined with Lefamulin. |
Enfortumab vedotin-ejfv Injection | Enfortumab vedotin-ejfv Injection The serum concentration of Lusutrombopag can be increased when it is combined with Enfortumab vedotin. |
Lasmiditan | Lasmiditan The serum concentration of Lusutrombopag can be increased when it is combined with Lasmiditan. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Lusutrombopag. |
Tazemetostat | Tazemetostat The serum concentration of Lusutrombopag can be increased when it is combined with Tazemetostat. |
Selumetinib | Selumetinib The serum concentration of Lusutrombopag can be increased when it is combined with Selumetinib. |
Rimegepant | Rimegepant The serum concentration of Lusutrombopag can be increased when it is combined with Rimegepant. |
Tucatinib | Tucatinib Tucatinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Remdesivir Injection | Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Lusutrombopag. |
Ripretinib | Ripretinib Ripretinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Capmatinib | Capmatinib The serum concentration of Lusutrombopag can be increased when it is combined with Capmatinib. |
Lemborexant | Lemborexant The serum concentration of Lusutrombopag can be increased when it is combined with Lemborexant. |
Fostemsavir | Fostemsavir Fostemsavir may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Lusutrombopag. |
Pralsetinib | Pralsetinib Pralsetinib may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Sulfasalazine | Sulfasalazine Sulfasalazine may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Dactinomycin | Dactinomycin The serum concentration of Lusutrombopag can be increased when it is combined with Dactinomycin. |
Loperamide | Loperamide The serum concentration of Lusutrombopag can be increased when it is combined with Loperamide. |
Digoxin | Digoxin The serum concentration of Digoxin can be increased when it is combined with Lusutrombopag. |
Loxapine | Loxapine The serum concentration of Lusutrombopag can be increased when it is combined with Loxapine. |
Quinine | Quinine The serum concentration of Lusutrombopag can be increased when it is combined with Quinine. |
Imipramine | Imipramine The serum concentration of Imipramine can be increased when it is combined with Lusutrombopag. |
Quinidine | Quinidine The serum concentration of Lusutrombopag can be increased when it is combined with Quinidine. |
Tamoxifen | Tamoxifen The serum concentration of Lusutrombopag can be increased when it is combined with Tamoxifen. |
Nortriptyline | Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Lusutrombopag. |
Clomiphene | Clomiphene The serum concentration of Lusutrombopag can be increased when it is combined with Clomifene. |
Colchicine | Colchicine The serum concentration of Lusutrombopag can be increased when it is combined with Colchicine. |
Ketoconazole | Ketoconazole The serum concentration of Lusutrombopag can be increased when it is combined with Ketoconazole. |
Vincristine Injection | Vincristine Injection The serum concentration of Vincristine can be increased when it is combined with Lusutrombopag. |
Vinblastine | Vinblastine The serum concentration of Lusutrombopag can be increased when it is combined with Vinblastine. |
Verapamil | Verapamil The serum concentration of Lusutrombopag can be increased when it is combined with Verapamil. |
Etoposide | Etoposide The serum concentration of Lusutrombopag can be increased when it is combined with Etoposide. |
Amiodarone | Amiodarone The serum concentration of Lusutrombopag can be increased when it is combined with Amiodarone. |
Clarithromycin | Clarithromycin The serum concentration of Lusutrombopag can be increased when it is combined with Clarithromycin. |
Pravastatin | Pravastatin Pravastatin may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Simvastatin | Simvastatin The serum concentration of Lusutrombopag can be increased when it is combined with Simvastatin. |
Itraconazole | Itraconazole The serum concentration of Lusutrombopag can be increased when it is combined with Itraconazole. |
Bisoprolol | Bisoprolol The serum concentration of Lusutrombopag can be increased when it is combined with Bisoprolol. |
Omeprazole | Omeprazole Omeprazole may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Venlafaxine | Venlafaxine Venlafaxine may increase the excretion rate of Lusutrombopag which could result in a lower serum level and potentially a reduction in efficacy. |
Lansoprazole | Lansoprazole Lansoprazole may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Saquinavir | Saquinavir The serum concentration of Lusutrombopag can be increased when it is combined with Saquinavir. |
Gemcitabine Injection | Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Lusutrombopag. |
Ritonavir | Ritonavir The serum concentration of Lusutrombopag can be increased when it is combined with Ritonavir. |
Nelfinavir | Nelfinavir Nelfinavir may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Fexofenadine | Fexofenadine The serum concentration of Lusutrombopag can be increased when it is combined with Fexofenadine. |
Carvedilol | Carvedilol The serum concentration of Lusutrombopag can be increased when it is combined with Carvedilol. |
Propafenone | Propafenone The serum concentration of Lusutrombopag can be increased when it is combined with Propafenone. |
Sildenafil | Sildenafil The serum concentration of Lusutrombopag can be increased when it is combined with Sildenafil. |
Rabeprazole | Rabeprazole Rabeprazole may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists