Thiotepa Injection

Generic name: Pronounced as (thye'' oh tep' a)
Brand names
  • Tepadina®
  • Thioplex®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 03/15/2013

Thiotepa is used to treat certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), breast, and bladder cancer. It is also used to treat malignant effusions (a condition when fluid collects in the lungs or around the heart) that are caused by cancerous tumors. Thiotepa is in a class of medications called alkylating agents. It works by slowing or stopping the growth of cancer cells in your body.

Thiotepa comes as a powder to be mixed with liquid to be injected intravenously (into a vein) by a doctor or nurse in a medical facility. It may also be injected intraperitoneally (into the abdominal cavity), intrapleurally (into the chest cavity), or intrapericardially (into the lining of the heart). The schedule for your treatment depends on your condition and on how you respond to thiotepa.

When used for bladder cancer, thiotepa is infused (injected slowly) into your bladder through a tube or catheter once a week for 4 weeks. Avoid drinking fluids for 8 to 12 hours before your treatment. You should keep the medication in your bladder for 2 hours. If you cannot keep the medication in your bladder for the entire 2 hours, tell your health care provider.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before receiving thiotepa,

  • tell your doctor and pharmacist if you are allergic to thiotepa, any other medications, or any of the ingredients in thiotepa injection. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

  • tell your doctor if you have or have ever had kidney or liver disease. Your doctor may not want you not to receive thiotepa.

  • tell your doctor if you have previously received or will be receiving radiation (x-ray) therapy or other chemotherapy and if you have or have ever had any medical conditions.

  • you should know that thiotepa may interfere with the normal menstrual cycle (period) in women, may stop sperm production in men, and may cause infertility (difficulty becoming pregnant). Women who are pregnant should tell their doctors before they begin receiving this drug. You or your partner should not become pregnant while you are receiving thiotepa. You should use birth control to prevent pregnancy in yourself or your partner during your treatment with thiotepa injection.

  • tell your doctor if you are breast-feeding. You should not breast-feed while you are receiving thiotepa.

Unless your doctor tells you otherwise, continue your normal diet.

  • Thiotepa may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nausea

    • vomiting

    • loss of appetite

    • stomach pain

    • unusual tiredness or weakness

    • dizziness

    • headache

    • blurry vision

    • sore or red eyes

    • hair loss

    • pain in the place where the medication was injected

  • Some side effects can be serious. If you experience any of these symptoms call your doctor immediately or get emergency medical treatment:

    • hives

    • rash

    • itching

    • difficulty breathing or swallowing

    • frequent, urgent, or painful urination

    • blood in the urine

    • fever, sore throat, chills, or other signs of infection

    • unusual bleeding or bruising

    • black and tarry stools

    • red blood in stools

    • bloody vomit; vomited material that looks like coffee grounds

    • nosebleed

  • Thiotepa may increase the risk that you will develop other cancers. Talk to your doctor about the risks of receiving thiotepa injection.

  • Thiotepa may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • fever, sore throat, chills, or other signs of infection

  • unusual bleeding or bruising

  • black and tarry stools

  • red blood in stools

  • bloody vomit; vomited material that looks like coffee grounds

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to thiotepa.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Thiotepa is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Thiotepa can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Nevirapine can be decreased when combined with Thiotepa.
Anagrelide Anagrelide The risk or severity of bleeding can be increased when Anagrelide is combined with Thiotepa.
Cilostazol Cilostazol The risk or severity of bleeding can be increased when Cilostazol is combined with Thiotepa.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Thiotepa.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Thiotepa can be decreased when combined with Erythromycin.
Fenofibrate Fenofibrate The metabolism of Thiotepa can be decreased when combined with Fenofibrate.
Methylergonovine Methylergonovine The metabolism of Thiotepa can be decreased when combined with Methylergometrine.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Thiotepa.
Penbutolol Penbutolol Thiotepa may increase the bradycardic activities of Acebutolol.
Prednisone Prednisone The therapeutic efficacy of Thiotepa can be decreased when used in combination with Prednisone.
Tacrolimus Tacrolimus Tacrolimus may increase the immunosuppressive activities of Thiotepa.
Triamcinolone Triamcinolone The therapeutic efficacy of Thiotepa can be decreased when used in combination with Triamcinolone.
Doxycycline Injection Doxycycline Injection The metabolism of Thiotepa can be decreased when combined with Doxycycline.
Fluconazole Injection Fluconazole Injection The metabolism of Thiotepa can be decreased when combined with Fluconazole.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Thiotepa.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Thiotepa.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be increased when combined with Thiotepa.
Methylprednisolone Injection Methylprednisolone Injection The therapeutic efficacy of Thiotepa can be decreased when used in combination with Methylprednisolone.
Metronidazole Injection Metronidazole Injection The metabolism of Thiotepa can be decreased when combined with Metronidazole.
Zidovudine Injection Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Thiotepa.
Cyclosporine Cyclosporine Thiotepa may increase the immunosuppressive activities of Cyclosporine.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding can be increased when Enoxaparin is combined with Thiotepa.
Olanzapine Olanzapine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Thiotepa.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Hydroxychloroquine is combined with Thiotepa.
Orlistat Orlistat The metabolism of Thiotepa can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Thiotepa can be increased when combined with Oxcarbazepine.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Thiotepa.
Anakinra Anakinra The metabolism of Thiotepa can be increased when combined with Anakinra.
Desloratadine Desloratadine The therapeutic efficacy of Desloratadine can be decreased when used in combination with Thiotepa.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Thiotepa.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Thiotepa.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Thiotepa.
Etanercept Injection Etanercept Injection The metabolism of Thiotepa can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate The therapeutic efficacy of Glycopyrronium can be decreased when used in combination with Thiotepa.
Modafinil Modafinil The metabolism of Thiotepa can be increased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Thiotepa can be decreased when combined with Tenofovir.
Sirolimus Sirolimus The risk or severity of adverse effects can be increased when Sirolimus is combined with Thiotepa.
Epinephrine Injection Epinephrine Injection The metabolism of Thiotepa can be decreased when combined with Epinephrine.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Thiotepa.
Escitalopram Escitalopram The therapeutic efficacy of Escitalopram can be decreased when used in combination with Thiotepa.
Adalimumab Injection Adalimumab Injection The metabolism of Thiotepa can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The therapeutic efficacy of Aripiprazole can be decreased when used in combination with Thiotepa.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Glatiramer.
Atazanavir Atazanavir The metabolism of Thiotepa can be decreased when combined with Atazanavir.
Mefloquine Mefloquine The metabolism of Thiotepa can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Thiotepa can be decreased when combined with Rosuvastatin.
Aprepitant Aprepitant The metabolism of Thiotepa can be decreased when combined with Aprepitant.
Progesterone Progesterone The metabolism of Thiotepa can be increased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Thiotepa.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Thiotepa.
Infliximab Injection Infliximab Injection The metabolism of Thiotepa can be increased when combined with Infliximab.
Rifaximin Rifaximin The metabolism of Thiotepa can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Thiotepa can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Thiotepa can be decreased when combined with Norethisterone.
Trospium Trospium The therapeutic efficacy of Trospium can be decreased when used in combination with Thiotepa.
Bosentan Bosentan The metabolism of Thiotepa can be increased when combined with Bosentan.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Natalizumab.
Erlotinib Erlotinib The metabolism of Thiotepa can be decreased when combined with Erlotinib.
Palifermin Palifermin The therapeutic efficacy of Palifermin can be decreased when used in combination with Thiotepa.
Solifenacin Solifenacin The therapeutic efficacy of Solifenacin can be decreased when used in combination with Thiotepa.
Voriconazole Voriconazole The metabolism of Thiotepa can be decreased when combined with Voriconazole.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Thiotepa.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Thiotepa.
Darifenacin Darifenacin The therapeutic efficacy of Darifenacin can be decreased when used in combination with Thiotepa.
Deferasirox Deferasirox The metabolism of Thiotepa can be increased when combined with Deferasirox.
Tipranavir Tipranavir The metabolism of Thiotepa can be decreased when combined with Tipranavir.
Felbamate Felbamate The metabolism of Thiotepa can be increased when combined with Felbamate.
Ranolazine Ranolazine The metabolism of Thiotepa can be decreased when combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Thiotepa can be increased when combined with Abatacept.
Imatinib Imatinib The metabolism of Thiotepa can be decreased when combined with Imatinib.
Varenicline Varenicline The risk or severity of adverse effects can be increased when Thiotepa is combined with Varenicline.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Thiotepa.
Gefitinib Gefitinib The metabolism of Thiotepa can be decreased when combined with Gefitinib.
Bortezomib Bortezomib The risk or severity of adverse effects can be increased when Bortezomib is combined with Thiotepa.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Thiotepa.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Thiotepa.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Thiotepa.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Thiotepa.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Thiotepa.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Thiotepa.
Posaconazole Posaconazole The metabolism of Thiotepa can be decreased when combined with Posaconazole.
Primaquine Primaquine The metabolism of Thiotepa can be decreased when combined with Primaquine.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Thiotepa.
Darunavir Darunavir The serum concentration of Thiotepa can be increased when it is combined with Darunavir.
Pemetrexed Injection Pemetrexed Injection The risk or severity of adverse effects can be increased when Pemetrexed is combined with Thiotepa.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Vorinostat is combined with Thiotepa.
Sorafenib Sorafenib The metabolism of Thiotepa can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Thiotepa can be decreased when combined with Sunitinib.
Lapatinib Lapatinib The metabolism of Thiotepa can be decreased when combined with Lapatinib.
Dasatinib Dasatinib The metabolism of Thiotepa can be decreased when combined with Dasatinib.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Thiotepa.
Armodafinil Armodafinil The metabolism of Thiotepa can be increased when combined with Armodafinil.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Thiotepa.
Ivermectin Ivermectin The metabolism of Thiotepa can be increased when combined with Ivermectin.
Temsirolimus Temsirolimus The risk or severity of adverse effects can be increased when Thiotepa is combined with Temsirolimus.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Thiotepa.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Thiotepa.
Nilotinib Nilotinib The metabolism of Nilotinib can be decreased when combined with Thiotepa.
Bexarotene Bexarotene The metabolism of Thiotepa can be increased when combined with Bexarotene.
Budesonide Budesonide The therapeutic efficacy of Thiotepa can be decreased when used in combination with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Thiotepa can be decreased when combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Thiotepa.
Etravirine Etravirine The metabolism of Thiotepa can be increased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Thiotepa.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Thiotepa can be decreased when combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The metabolism of Thiotepa can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline The risk or severity of adverse effects can be increased when Thiotepa is combined with Cevimeline.
Nebivolol Nebivolol Thiotepa may increase the bradycardic activities of Nebivolol.
Tretinoin Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Thiotepa.
Bendamustine Injection Bendamustine Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Bendamustine.
Pilocarpine Pilocarpine The metabolism of Pilocarpine can be decreased when combined with Thiotepa.
Certolizumab Injection Certolizumab Injection The metabolism of Certolizumab pegol can be increased when combined with Thiotepa.
Ixabepilone Injection Ixabepilone Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Ixabepilone.
Irinotecan Injection Irinotecan Injection The risk or severity of adverse effects can be increased when Irinotecan is combined with Thiotepa.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Thiotepa.
Mitotane Mitotane The metabolism of Thiotepa can be increased when combined with Mitotane.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Thiotepa.
Rufinamide Rufinamide The metabolism of Thiotepa can be increased when combined with Rufinamide.
Midazolam Midazolam The metabolism of Thiotepa can be decreased when combined with Midazolam.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Thiotepa.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Thiotepa.
Milnacipran Milnacipran The metabolism of Thiotepa can be decreased when combined with Milnacipran.
Fesoterodine Fesoterodine The therapeutic efficacy of Fesoterodine can be decreased when used in combination with Thiotepa.
Betaxolol Betaxolol Thiotepa may increase the bradycardic activities of Betaxolol.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Thiotepa.
Lacosamide Lacosamide The metabolism of Thiotepa can be decreased when combined with Lacosamide.
Everolimus Everolimus The risk or severity of adverse effects can be increased when Everolimus is combined with Thiotepa.
Dronedarone Dronedarone The serum concentration of Thiotepa can be increased when it is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Pralatrexate.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Thiotepa.
Topotecan Topotecan The metabolism of Thiotepa can be increased when combined with Topotecan.
Golimumab Injection Golimumab Injection The metabolism of Golimumab can be increased when combined with Thiotepa.
Pazopanib Pazopanib The metabolism of Pazopanib can be decreased when combined with Thiotepa.
Albendazole Albendazole The metabolism of Thiotepa can be decreased when combined with Albendazole.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Thiotepa.
Dabigatran Dabigatran The risk or severity of bleeding can be increased when Dabigatran is combined with Thiotepa.
Tocilizumab Injection Tocilizumab Injection The metabolism of Tocilizumab can be increased when combined with Thiotepa.
Fingolimod Fingolimod Thiotepa may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Cabazitaxel.
Acetaminophen Injection Acetaminophen Injection The metabolism of Thiotepa can be increased when combined with Acetaminophen.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Thiotepa can be decreased when combined with Aldesleukin.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Thiotepa.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Belimumab.
Busulfan Injection Busulfan Injection The risk or severity of adverse effects can be increased when Busulfan is combined with Thiotepa.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Thiotepa.
Linagliptin Linagliptin The metabolism of Thiotepa can be decreased when combined with Linagliptin.
Rilpivirine Rilpivirine The metabolism of Thiotepa can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The metabolism of Thiotepa can be decreased when combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Thiotepa can be increased when combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban The risk or severity of bleeding can be increased when Rivaroxaban is combined with Thiotepa.
Ticagrelor Ticagrelor The metabolism of Thiotepa can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Thiotepa.
Ruxolitinib Ruxolitinib The risk or severity of adverse effects can be increased when Thiotepa is combined with Ruxolitinib.
Clobazam Clobazam The metabolism of Clobazam can be increased when combined with Thiotepa.
Vemurafenib Vemurafenib The metabolism of Thiotepa can be increased when combined with Vemurafenib.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Belatacept.
Ivacaftor Ivacaftor The metabolism of Thiotepa can be decreased when combined with Ivacaftor.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Thiotepa.
Crizotinib Crizotinib The metabolism of Thiotepa can be decreased when combined with Crizotinib.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Thiotepa.
Cabergoline Cabergoline The metabolism of Thiotepa can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Thiotepa can be decreased when combined with Naloxone.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Thiotepa.
Fondaparinux Injection Fondaparinux Injection The risk or severity of bleeding can be increased when Fondaparinux is combined with Thiotepa.
Carfilzomib Injection Carfilzomib Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Carfilzomib.
Iloprost Iloprost The risk or severity of bleeding can be increased when Iloprost is combined with Thiotepa.
Enzalutamide Enzalutamide The metabolism of Thiotepa can be increased when combined with Enzalutamide.
Mirabegron Mirabegron Thiotepa may increase the neuromuscular blocking activities of Mirabegron.
Regorafenib Regorafenib The metabolism of Thiotepa can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Bosutinib can be decreased when combined with Thiotepa.
Corticotropin, Repository Injection Corticotropin, Repository Injection The therapeutic efficacy of Thiotepa can be decreased when used in combination with Corticotropin.
Teriflunomide Teriflunomide The risk or severity of adverse effects can be increased when Thiotepa is combined with Teriflunomide.
Icosapent Ethyl Icosapent Ethyl The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Thiotepa.
Tofacitinib Tofacitinib Thiotepa may increase the immunosuppressive activities of Tofacitinib.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Thiotepa is combined with Dimethyl fumarate.
Ponatinib Ponatinib The risk or severity of adverse effects can be increased when Thiotepa is combined with Ponatinib.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Thiotepa is combined with Pomalidomide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Thiotepa.
Apixaban Apixaban The risk or severity of bleeding can be increased when Apixaban is combined with Thiotepa.
Dabrafenib Dabrafenib The metabolism of Thiotepa can be increased when combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Thiotepa.
Trametinib Trametinib The metabolism of Thiotepa can be increased when combined with Trametinib.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Thiotepa.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Thiotepa.
Ibrutinib Ibrutinib The risk or severity of adverse effects can be increased when Thiotepa is combined with Ibrutinib.
Lomitapide Lomitapide The metabolism of Thiotepa can be decreased when combined with Lomitapide.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Obinutuzumab.
Simeprevir Simeprevir The metabolism of Thiotepa can be decreased when combined with Simeprevir.
Apremilast Apremilast The metabolism of Apremilast can be increased when combined with Thiotepa.
Ceritinib Ceritinib The metabolism of Thiotepa can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Siltuximab can be increased when combined with Thiotepa.
Eslicarbazepine Eslicarbazepine The metabolism of Thiotepa can be increased when combined with Eslicarbazepine.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Belinostat.
Idelalisib Idelalisib The risk or severity of adverse effects can be increased when Idelalisib is combined with Thiotepa.
Testosterone Injection Testosterone Injection The metabolism of Thiotepa can be increased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Thiotepa can be increased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Thiotepa can be decreased when combined with Vorapaxar.
Hydrocodone Hydrocodone The metabolism of Thiotepa can be decreased when combined with Hydrocodone.
Suvorexant Suvorexant The metabolism of Thiotepa can be decreased when combined with Suvorexant.
Edoxaban Edoxaban The risk or severity of bleeding can be increased when Edoxaban is combined with Thiotepa.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Thiotepa.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Blinatumomab.
Tasimelteon Tasimelteon The metabolism of Thiotepa can be decreased when combined with Tasimelteon.
Lanreotide Injection Lanreotide Injection The metabolism of Thiotepa can be decreased when combined with Lanreotide.
Pirfenidone Pirfenidone The risk or severity of adverse effects can be increased when Thiotepa is combined with Pirfenidone.
Nintedanib Nintedanib The metabolism of Thiotepa can be decreased when combined with Nintedanib.
Secukinumab Injection Secukinumab Injection The metabolism of Secukinumab can be increased when combined with Thiotepa.
Palbociclib Palbociclib The metabolism of Palbociclib can be decreased when combined with Thiotepa.
Lenvatinib Lenvatinib The metabolism of Thiotepa can be increased when combined with Lenvatinib.
Panobinostat Panobinostat The risk or severity of adverse effects can be increased when Thiotepa is combined with Panobinostat.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Thiotepa.
Isavuconazonium Injection Isavuconazonium Injection The metabolism of Thiotepa can be increased when combined with Isavuconazonium.
Prednisolone Prednisolone The therapeutic efficacy of Thiotepa can be decreased when used in combination with Prednisolone.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be decreased when combined with Thiotepa.
Cobimetinib Cobimetinib The metabolism of Thiotepa can be decreased when combined with Cobimetinib.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Mepolizumab.
Trabectedin Injection Trabectedin Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Trabectedin.
Osimertinib Osimertinib The metabolism of Thiotepa can be increased when combined with Osimertinib.
Rifapentine Rifapentine The metabolism of Thiotepa can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Thiotepa can be increased when combined with Lesinurad.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Thiotepa can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The therapeutic efficacy of Thiotepa can be decreased when used in combination with Dexamethasone.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding can be increased when Defibrotide is combined with Thiotepa.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Ixekizumab.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Thiotepa.
Venetoclax Venetoclax The metabolism of Thiotepa can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The metabolism of Thiotepa can be decreased when combined with Cobicistat.
Diphenhydramine Injection Diphenhydramine Injection The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Thiotepa.
Rucaparib Rucaparib The metabolism of Thiotepa can be decreased when combined with Rucaparib.
Ribociclib Ribociclib The metabolism of Thiotepa can be decreased when combined with Ribociclib.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Thiotepa can be increased when combined with Brigatinib.
Doxepin (Insomnia) Doxepin (Insomnia) The therapeutic efficacy of Doxepin can be decreased when used in combination with Thiotepa.
Deflazacort Deflazacort The therapeutic efficacy of Deflazacort can be decreased when used in combination with Thiotepa.
Ocrelizumab Injection Ocrelizumab Injection Ocrelizumab may increase the immunosuppressive activities of Thiotepa.
Sarilumab Injection Sarilumab Injection The metabolism of Sarilumab can be increased when combined with Thiotepa.
Midostaurin Midostaurin The metabolism of Thiotepa can be increased when combined with Midostaurin.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Guselkumab.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Thiotepa.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Thiotepa can be increased when combined with Fosaprepitant.
Betrixaban Betrixaban The risk or severity of bleeding can be increased when Betrixaban is combined with Thiotepa.
Acalabrutinib Acalabrutinib The metabolism of Thiotepa can be decreased when combined with Acalabrutinib.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Thiotepa.
Letermovir Letermovir The metabolism of Thiotepa can be decreased when combined with Letermovir.
Buprenorphine Injection Buprenorphine Injection The metabolism of Thiotepa can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The metabolism of Thiotepa can be increased when combined with Apalutamide.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Thiotepa.
Fostamatinib Fostamatinib The metabolism of Thiotepa can be decreased when combined with Fostamatinib.
Baricitinib Baricitinib The risk or severity of adverse effects can be increased when Thiotepa is combined with Baricitinib.
Ivosidenib Ivosidenib The metabolism of Thiotepa can be increased when combined with Ivosidenib.
Dacomitinib Dacomitinib The metabolism of Thiotepa can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Thiotepa can be decreased when combined with Duvelisib.
Stiripentol Stiripentol The metabolism of Thiotepa can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The metabolism of Thiotepa can be decreased when combined with Gilteritinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Thiotepa.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Thiotepa can be increased when combined with Paclitaxel.
Rifamycin Rifamycin The metabolism of Thiotepa can be increased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Thiotepa can be decreased when combined with Prucalopride.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Emapalumab can be increased when combined with Thiotepa.
Siponimod Siponimod The risk or severity of adverse effects can be increased when Thiotepa is combined with Siponimod.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Caplacizumab is combined with Thiotepa.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Risankizumab.
Alpelisib Alpelisib The metabolism of Thiotepa can be increased when combined with Alpelisib.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Thiotepa.
Triclabendazole Triclabendazole The metabolism of Thiotepa can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Thiotepa.
Pitolisant Pitolisant The serum concentration of Thiotepa can be decreased when it is combined with Pitolisant.
Lefamulin Lefamulin The serum concentration of Thiotepa can be increased when it is combined with Lefamulin.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be increased when combined with Thiotepa.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Thiotepa can be increased when combined with Fosphenytoin.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Thiotepa.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Thiotepa.
Tazemetostat Tazemetostat The metabolism of Thiotepa can be decreased when combined with Tazemetostat.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Thiotepa.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Thiotepa is combined with Ozanimod.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Thiotepa.
Octreotide Octreotide The serum concentration of Thiotepa can be increased when it is combined with Octreotide.
Pralsetinib Pralsetinib The metabolism of Thiotepa can be increased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Thiotepa can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Thiotepa can be decreased when combined with Drospirenone.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Thiotepa can be increased when combined with Vitamin E.
Indomethacin Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Thiotepa.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Thiotepa.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Thiotepa.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be increased when combined with Thiotepa.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Methotrexate is combined with Thiotepa.
Primidone Primidone The metabolism of Primidone can be increased when combined with Thiotepa.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Thiotepa.
Diazepam Diazepam The metabolism of Thiotepa can be decreased when combined with Diazepam.
Lorazepam Lorazepam The metabolism of Thiotepa can be decreased when combined with Lorazepam.
Carmustine Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Thiotepa.
Amantadine Amantadine The therapeutic efficacy of Amantadine can be decreased when used in combination with Thiotepa.
Bromocriptine Bromocriptine The metabolism of Thiotepa can be decreased when combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Thiotepa can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Thiotepa can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Thiotepa.
Tetracycline Tetracycline The metabolism of Thiotepa can be decreased when combined with Tetracycline.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Thiotepa.
Prochlorperazine Prochlorperazine The metabolism of Thiotepa can be decreased when combined with Prochlorperazine.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Thiotepa.
Methadone Methadone The metabolism of Methadone can be increased when combined with Thiotepa.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Thiotepa.
Benztropine Benztropine The therapeutic efficacy of Benzatropine can be decreased when used in combination with Thiotepa.
Maprotiline Maprotiline The therapeutic efficacy of Maprotiline can be decreased when used in combination with Thiotepa.
Trihexyphenidyl Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Thiotepa.
Orphenadrine Orphenadrine The metabolism of Orphenadrine can be decreased when combined with Thiotepa.
Azathioprine Azathioprine The risk or severity of adverse effects can be increased when Azathioprine is combined with Thiotepa.
Phentermine Phentermine The metabolism of Thiotepa can be decreased when combined with Phentermine.
Amoxapine Amoxapine The therapeutic efficacy of Amoxapine can be decreased when used in combination with Thiotepa.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Thiotepa.
Hydrocortisone Hydrocortisone The therapeutic efficacy of Thiotepa can be decreased when used in combination with Hydrocortisone.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Thiotepa.
Doxorubicin Doxorubicin The metabolism of Thiotepa can be decreased when combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Thiotepa.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Thiotepa.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Thiotepa.
Carbamazepine Carbamazepine The metabolism of Thiotepa can be increased when combined with Carbamazepine.
Hydralazine Hydralazine The metabolism of Thiotepa can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Thiotepa can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Thiotepa can be increased when combined with Warfarin.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Thiotepa.
Promethazine Promethazine The metabolism of Promethazine can be decreased when combined with Thiotepa.
Daunorubicin Daunorubicin The metabolism of Thiotepa can be decreased when combined with Daunorubicin.
Griseofulvin Griseofulvin The metabolism of Thiotepa can be increased when combined with Griseofulvin.
Quinine Quinine The metabolism of Thiotepa can be increased when combined with Quinine.
Calcitriol Calcitriol The metabolism of Thiotepa can be increased when combined with Calcitriol.
Sulfinpyrazone Sulfinpyrazone The metabolism of Thiotepa can be increased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Chlorothiazide is combined with Thiotepa.
Secobarbital Secobarbital The metabolism of Secobarbital can be increased when combined with Thiotepa.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Thiotepa.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Thiotepa.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Thiotepa.
Probenecid Probenecid The metabolism of Thiotepa can be increased when combined with Probenecid.
Quinidine Quinidine The metabolism of Quinidine can be decreased when combined with Thiotepa.
Isoniazid Isoniazid The metabolism of Thiotepa can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Thiotepa can be increased when combined with Rifampicin.
Disopyramide Disopyramide The therapeutic efficacy of Disopyramide can be decreased when used in combination with Thiotepa.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be decreased when combined with Thiotepa.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Thiotepa.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Thiotepa.
Butabarbital Butabarbital The therapeutic efficacy of Butabarbital can be decreased when used in combination with Thiotepa.
Methimazole Methimazole The metabolism of Thiotepa can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Thiotepa.
Dextromethorphan Dextromethorphan The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Thiotepa.
Niacin Niacin The metabolism of Thiotepa can be decreased when combined with Niacin.
Doxylamine Doxylamine The therapeutic efficacy of Doxylamine can be decreased when used in combination with Thiotepa.
Cyproheptadine Cyproheptadine The therapeutic efficacy of Cyproheptadine can be decreased when used in combination with Thiotepa.
Brompheniramine Brompheniramine The metabolism of Brompheniramine can be decreased when combined with Thiotepa.
Methyclothiazide Methyclothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Thiotepa.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Hydrochlorothiazide is combined with Thiotepa.
Danazol Danazol The metabolism of Thiotepa can be decreased when combined with Danazol.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Thiotepa may increase the bradycardic activities of Propranolol.
Nortriptyline Nortriptyline The therapeutic efficacy of Nortriptyline can be decreased when used in combination with Thiotepa.
Amphotericin B Injection Amphotericin B Injection The metabolism of Thiotepa can be decreased when combined with Amphotericin B.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Thiotepa.
Nadolol Nadolol Thiotepa may increase the bradycardic activities of Nadolol.
Allopurinol Allopurinol The risk or severity of adverse effects can be increased when Allopurinol is combined with Thiotepa.
Flavoxate Flavoxate The therapeutic efficacy of Flavoxate can be decreased when used in combination with Thiotepa.
Fluorouracil Injection Fluorouracil Injection The risk or severity of adverse effects can be increased when Fluorouracil is combined with Thiotepa.
Colchicine Colchicine The metabolism of Thiotepa can be increased when combined with Colchicine.
Cephalexin Cephalexin The metabolism of Thiotepa can be decreased when combined with Cephalexin.
Dacarbazine Dacarbazine The risk or severity of adverse effects can be increased when Dacarbazine is combined with Thiotepa.
Acetazolamide Acetazolamide The metabolism of Thiotepa can be decreased when combined with Acetazolamide.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Thiotepa.
Ketoconazole Ketoconazole The metabolism of Thiotepa can be decreased when combined with Ketoconazole.
Vincristine Injection Vincristine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Thiotepa.
Dipyridamole Dipyridamole The therapeutic efficacy of Thiotepa can be decreased when used in combination with Dipyridamole.
Vinblastine Vinblastine The metabolism of Thiotepa can be increased when combined with Vinblastine.
Bethanechol Bethanechol The risk or severity of adverse effects can be increased when Thiotepa is combined with Bethanechol.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Thiotepa.
Aspirin Aspirin The risk or severity of bleeding can be increased when Acetylsalicylic acid is combined with Thiotepa.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Thiotepa.
Dicyclomine Dicyclomine The therapeutic efficacy of Dicyclomine can be decreased when used in combination with Thiotepa.
Hyoscyamine Hyoscyamine The therapeutic efficacy of Hyoscyamine can be decreased when used in combination with Thiotepa.
Propantheline Propantheline The therapeutic efficacy of Propantheline can be decreased when used in combination with Thiotepa.
Diltiazem Diltiazem The metabolism of Thiotepa can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Thiotepa can be increased when combined with Nifedipine.
Timolol Timolol Thiotepa may increase the bradycardic activities of Timolol.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Thiotepa.
Atenolol Atenolol Thiotepa may increase the bradycardic activities of Atenolol.
Pindolol Pindolol Thiotepa may increase the bradycardic activities of Pindolol.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Thiotepa.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Thiotepa.
Etoposide Etoposide The metabolism of Thiotepa can be increased when combined with Etoposide.
Glyburide Glyburide The metabolism of Thiotepa can be decreased when combined with Glyburide.
Dicloxacillin Dicloxacillin The metabolism of Thiotepa can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Thiotepa can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline The risk or severity of bleeding can be increased when Pentoxifylline is combined with Thiotepa.
Labetalol Labetalol Thiotepa may increase the bradycardic activities of Labetalol.
Pimozide Pimozide The metabolism of Thiotepa can be decreased when combined with Pimozide.
Amiodarone Amiodarone The metabolism of Thiotepa can be decreased when combined with Amiodarone.
Lovastatin Lovastatin The metabolism of Thiotepa can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The metabolism of Thiotepa can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Thiotepa.
Fluoxetine Fluoxetine The metabolism of Fluoxetine can be decreased when combined with Thiotepa.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Thiotepa.
Clozapine Clozapine The risk or severity of neutropenia can be increased when Thiotepa is combined with Clozapine.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Idarubicin is combined with Thiotepa.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Thiotepa.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Thiotepa.
Clarithromycin Clarithromycin The metabolism of Thiotepa can be decreased when combined with Clarithromycin.
Felodipine Felodipine The metabolism of Thiotepa can be decreased when combined with Felodipine.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Thiotepa.
Teniposide Injection Teniposide Injection The metabolism of Thiotepa can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Thiotepa can be decreased when combined with Itraconazole.
Rifabutin Rifabutin The metabolism of Thiotepa can be increased when combined with Rifabutin.
Sotalol Sotalol Thiotepa may increase the bradycardic activities of Sotalol.
Bisoprolol Bisoprolol Thiotepa may increase the bradycardic activities of Bisoprolol.
Doxazosin Doxazosin The metabolism of Thiotepa can be decreased when combined with Doxazosin.
Isradipine Isradipine The metabolism of Thiotepa can be decreased when combined with Isradipine.
Omeprazole Omeprazole The metabolism of Thiotepa can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Thiotepa.
Fluvastatin Fluvastatin The metabolism of Thiotepa can be decreased when combined with Fluvastatin.
Famciclovir Famciclovir The metabolism of Thiotepa can be decreased when combined with Famciclovir.
Fluvoxamine Fluvoxamine The metabolism of Thiotepa can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Thiotepa can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine The therapeutic efficacy of Lamotrigine can be decreased when used in combination with Thiotepa.
Losartan Losartan The metabolism of Thiotepa can be decreased when combined with Losartan.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Thiotepa.
Vinorelbine Injection Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Thiotepa.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Thiotepa.
Lansoprazole Lansoprazole The metabolism of Thiotepa can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Thiotepa can be increased when combined with Ifosfamide.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Thiotepa.
Nicardipine Nicardipine The metabolism of Nicardipine can be decreased when combined with Thiotepa.
Bupropion Bupropion The serum concentration of Bupropion can be increased when it is combined with Thiotepa.
Ticlopidine Ticlopidine The metabolism of Thiotepa can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Thiotepa can be decreased when combined with Saquinavir.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding can be increased when Dalteparin is combined with Thiotepa.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Thiotepa.
Ritonavir Ritonavir The serum concentration of Thiotepa can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Thiotepa can be decreased when combined with Docetaxel.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Thiotepa.
Zafirlukast Zafirlukast The metabolism of Thiotepa can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Thiotepa can be decreased when combined with Mirtazapine.
Topiramate Topiramate The metabolism of Thiotepa can be increased when combined with Topiramate.
Azithromycin Azithromycin The metabolism of Thiotepa can be decreased when combined with Azithromycin.
Carvedilol Carvedilol Thiotepa may increase the bradycardic activities of Carvedilol.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Thiotepa.
Bicalutamide Bicalutamide The metabolism of Thiotepa can be decreased when combined with Bicalutamide.
Propafenone Propafenone Thiotepa may increase the bradycardic activities of Propafenone.
Raloxifene Raloxifene The metabolism of Thiotepa can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Thiotepa can be decreased when combined with Irbesartan.
Quetiapine Quetiapine The therapeutic efficacy of Thiotepa can be decreased when used in combination with Quetiapine.
Paroxetine Paroxetine The metabolism of Paroxetine can be decreased when combined with Thiotepa.
Citalopram Citalopram The metabolism of Thiotepa can be decreased when combined with Citalopram.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Capecitabine is combined with Thiotepa.
Efavirenz Efavirenz The metabolism of Efavirenz can be increased when combined with Thiotepa.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Thiotepa.
Tolterodine Tolterodine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Thiotepa.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Thiotepa.
Rabeprazole Rabeprazole The metabolism of Thiotepa can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Thiotepa can be increased when combined with Terbinafine.

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