NDC 00096-0735-08 — DHS ZINC pyrithione 20 mg/mL Shampoo, 240 mL

🆔 Identity & classification

FDA NDC (as labeled) 0096-0735-08

Product NDC 0096-0735

11-digit billing NDC 00096073508

NCPDP billing unit ML — per mL (volume)

RxCUI 244458, 1101729

UNII R953O2RHZ5

Application # M032

SPL Set ID 39712814-4fe6-2a5b-e063-6294a90ab8cc

DEA schedule Non-controlled

Marketing category OTC MONOGRAPH DRUG

Marketing status Discontinued

FDA listing status Discontinued by firm (certified through Mar 2025)

Marketing start 1995-06-01

Route TOPICAL

Dosage form SHAMPOO

Substance PYRITHIONE ZINC

GPI-14 90300040004520

GPI class DHS Zinc

GCN Seq No 006176

GCN 24171

HICL code 013409

Ingredient (HICL) Pyrithione Zinc

HIC1 code L

Therapeutic class — broad (HIC1) Skin/Subcutaneous Tissue

HIC2 code L5

Therapeutic class — intermediate (HIC2) Keratolytics/Keratoplastics

HIC3 code L5E

Therapeutic class — specific (HIC3) Antiseborrheic Agents

AHFS code 84:04.92.00

AHFS class Local Anti-Infectives, Miscellaneous

FDB label name DHS ZINC 2% SHAMPOO

FDB brand name Dhs Zinc

Legend status O — Over-the-counter (OTC) drug or device

Why two NDCs? The FDA registers this code as 0096-0735-08 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00096-0735-08. Same drug, same package — only the format differs.

Where does this data come from?

Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Other dermatologicals class.

Drug family (ATC) Other dermatologicals

Where does this data come from?

Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerPerson and Covey

FDA applicationM032 (OTC MONOGRAPH DRUG)

Labeler code00096

First marketedJun 1995

Product typeHuman Otc Drug

Portfolio23 products on file

🔎 All NDCs from Person and Covey

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).

Where does this data come from?

Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name DHS ZINC 2% SHAMPOO Ingredient Pyrithione Zinc

🧪 What is this product?

DHS Zinc is an over-the-counter shampoo containing pyrithione zinc, a topical agent commonly used to help reduce flaking and itching associated with dandruff and seborrheic dermatitis of the scalp. This product is marketed as an OTC monograph drug, meaning it follows established FDA guidelines for its category rather than undergoing individual application review. Pyrithione zinc is typically applied to the scalp during shampooing to help manage these scalp conditions.

Patient education

📘 MedlinePlus patient leaflet ↗

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →

Where does this data come from?

Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

UNII 62V75NI93W
A surfactant derived from coconut oil that helps cleanse and remove oils from skin or hair. In medicines and personal care products, it acts as a cleanser and foaming agent.
UNII H77VEI93A8
A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
UNII 3NXW29V3WO
Hypromellose is a plant-based thickener made from cellulose. It's used in medicines as a binder to hold ingredients together, a coating for tablets, and a thickener for liquids.
UNII 6M3P64V0NC
A fine powder made from magnesium, aluminum, and silicon compounds. It absorbs moisture and helps keep medicine ingredients from clumping or separating, so the product stays stable and flows smoothly during manufacturing.
UNII 7JNC8VN07M
A synthetic compound made from polyethylene glycol combined with stearic acid. It acts as an emulsifier and surfactant to help mix oil and water-based ingredients and improve how the medicine spreads or dissolves.
UNII 451W47IQ8X
Sodium chloride is common table salt. It's used in medicines as a buffer to maintain proper pH, as a filler to add bulk, or to adjust the osmotic balance in liquid formulations.
UNII E8458C1KAA
A synthetic detergent and cleansing agent derived from lauric acid. It helps break down oils and improve how active ingredients mix into the formula, and may also serve as a foaming or emulsifying agent in topical preparations.
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesPurified Water TEA Lauryl Sulfate Cocamidopropyl Hydroxysultaine Sodium Chloride PEG 8 Distearate Methocel E4M Premium Veegum Herbal Bouquet No. 1751 Perfume FD&C Yellow No.6

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?

Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?

No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.

Why might an inactive ingredient be missing?

Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.

Can inactive ingredients matter?

Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price system	Per g	Per package
Retail pharmacies payNADAC · weekly	Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo	No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly	No Part D plan price is available for this NDC in our data.

ℹ️

No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.

Try another pack size: 480 ml

Where does this data come from?

NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

Product	Labeler	Pack	NADAC/unit	TE	Status	Price vs. this
Dhs Zinc 20 mg/mLthis 00096-0735-08	Person	240 ml	—	—	Discontinued	—
Dhs Zinc 20 mg/mL 00096-0811-08	Person	240 ml	—	—	FDA listed	—
DermaZinc 2 g/100mL 35324-0003-08	WynnPharm	240 ml	—	—	FDA listed	—
DermaZinc 2 g/100g 35324-0004-04	WynnPharm	120 g	—	—	FDA listed	—
Vanicream 2 g/100mL 45334-0206-07	Pharmaceutical	7.4 ml	—	—	FDA listed	—
Zolidyne 20 mg/mL 51326-0203-67	Topiderm,	200 ml	—	—	FDA listed	—
Flakes Cedar Mint Anti Dandruff .02 kg/kg 52261-1400-01	Cosco	266 kg	—	—	FDA listed	—
Denorex Severe Flakes Medicated Anti Dandruff .02 g/mL 62673-0176-10	Neoteric	1 bottle	—	—	FDA listed	—
Divine Dandrene 2% 2 g/100mL 69188-0200-07	DS	205 ml	—	—	FDA listed	—
Dermaharmony Pyrithione Zinc with Shea Butter 2 g/100g 71819-0017-37	D3	105 g	—	—	FDA listed	—
Dermaharmony Tea Tree Bar 2 g/100g 71819-0018-04	D3	113 g	—	—	FDA listed	—
Dermaharmony Unscented Bar 2 g/100g 71819-0019-04	D3	113 g	—	—	FDA listed	—
Dzul Anti-Dandruff Conditioner 2 g/100mL 83037-0002-08	Caball	236 ml	—	—	FDA listed	—
Dandrx Anti-Dandruff 2 g/100mL 85521-0002-08	dandRX	237 ml	—	—	FDA listed	—
Happy Head Anti-Dandruff 20 mg/mL 87117-0970-00	Happy	177 ml	—	—	FDA listed	—

About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.

Where does this data come from?

Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️

1995

On the market since

Jun 1995

📍

2026

Currently FDA-listed

31 years listed

🔒

·

No generic listed yet

brand only

ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?

Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Pyrithione zinc — the ingredient across all brands.

Top reported reactions

Pruritus93

Dry Skin58

Rash58

Skin Exfoliation42

Dermatitis Atopic35

Erythema35

Headache32

Age at onset

Infant3

Child31

Adolescent24

Adult140

Elderly61

Reporter sex

Male · 42%

Female · 58%

Serious outcomes

Hospitalization89

Disabling11

Death10

Life-threatening2

Reports over time (by year) — tap or hover for the count & year

Most recent year is provisional (FAERS lags ~3 months).

Where does this data come from?

Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDC	Description	Per unit	Per pack	Marketing start	Status
00096-0735-08 You're viewing this	240 mL in 1 BOTTLE (0096-0735-08)	—	—	1995-06-01	Discontinued by firm
00096-0735-16	480 mL in 1 BOTTLE (0096-0735-16)	$0.0249 / mL	$11.94	1995-06-01	Discontinued by firm

You're viewing the smallest of 2 pack sizes for this product.

Pack size FAQ

What quantity is in NDC 00096-0735-08?

NDC 00096-0735-08 contains 240 mL — 240 ml in 1 bottle.

What is the difference between NDC 00096-0735-08 and NDC 00096-0735-16?

Both are DHS ZINC pyrithione 20 mg/mL Shampoo — the drug itself is identical. NDC 00096-0735-08 is the 240 mL package, while NDC 00096-0735-16 is the 480 ml package.

What NDC number is used to bill for this package of DHS ZINC pyrithione 20 mg/mL Shampoo?

Bill NDC 00096-0735-08 — the 11-digit billing format is 00096073508. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)

What data is (and isn’t) available for this NDC — tap to expand

NDC identity (package / product / labeler codes)	✓ Available
Labeler	✓ Available
Product & package description	✓ Available
Marketing category & status	✓ Available
Active ingredient / dosage form / route	✓ Available
FDA label (SPL via DailyMed)	✓ Available
Package photos	✓ Available
Inactive ingredients (structured)	✓ Available
NADAC pharmacy acquisition price (CMS)	— Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data	— Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk	— Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD)	— Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.

“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?

An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.

Why is there no price listed?

The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.

What does the discontinued status mean for this NDC?

The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.

Is the NDC printed on the package the same as the 11-digit billing NDC?

Yes, they identify this exact package in different formats. The FDA registers it as 0096-0735-08, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 00096-0735-08, written without dashes as 00096073508. The Identity section at the top of this page lists every form of this code.

What do the three segments of this NDC mean?

In 00096-0735-08, the first segment (00096) is the labeler code FDA assigned to Person and Covey; the middle segment (0735) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (08) identifies this exact package size and type. Together they name one specific package of one specific product.

Does this product come in other package sizes?

Yes — the FDA directory lists 1 other package presentation of this same product, including 480 ml (00096-0735-16). Each has its own NDC and its own page — see the package list near the top of this page.

Who lists this product with the FDA?

Person and Covey is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.

Do I need a prescription for this product?

This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.

This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.

Where does this data come from?

Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.

🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose

🎯 Indications and Usage 17 words ▾

Indications and Use Helps prevent recurrence of scalp itching and flaking associated with Seborrheic Dermatitis and Dandruff.

⏱️ Dosage and Administration 52 words ▾

Dosage and Administration Shake well before using. Wet hair thoroughly. Apply a liberal amount of shampoo and massage into a rich lather. Allow lather to remain on scalp for several minutes. Rinse hair well and repeat application. For best results use at least twice a week or as directed by a physician.

⚠️ Warnings 56 words ▾

WARNINGS AND PRECAUTIONS For external use only. Ask a physician before use if you have Psoriasis or Seborrheic Dermatitis that covers a large area of the body. Do not get into eyes. If contact occurs, rinse eyes thoroughly with water. Stop use and ask a physician if condition worsens or does not improve after regular use.

🧪 Active Ingredient 4 words ▾

Active Ingredient pyrithione zinc

🧪 Inactive Ingredients 26 words ▾

INACTIVE INGREDIENTS Purified Water TEA Lauryl Sulfate Cocamidopropyl Hydroxysultaine Sodium Chloride PEG 8 Distearate Methocel E4M Premium Veegum Herbal Bouquet No. 1751 Perfume FD&C Yellow No.6

🎯 Purpose 9 words ▾

PURPOSE Recommended for control of Dandruff of Seborrheic Dermatitis

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

🔗 Related NDC lookups

🧪 All Pyrithione Zinc NDCsSame ingredient 🏭 All Person labeler NDCsLabeler code 00096

💊 Related drugs in this class

Other drugs that share this product’s specific therapeutic class — Antiseborrheic Agents.

Sulfacetamide Sodium 00178-0485-04 Selenium Sulfide 00536-1995-53

Where does this data come from?

Other drugs sharing this product’s First Databank therapeutic class (HIC3). Each links to that NDC’s page in our directory.