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CITRUCEL methylcellulose 500 mg Tablet, 100-count — NDC 00135-0199-02 package photo

CITRUCEL methylcellulose 500 mg Tablet, 100-count

by Haleon US Holdings LLC · 100 TABLET in 1 BOTTLE (0135-0199-02)
NDC 00135-0199-02
🏷️ FDA NDC (as labeled) 0135-0199-02 billing pads the labeler segment with a zero
This package
Contains100-count Pack sizes6 compare ↓
Also comes in: 2 tablets 00135-0199-06 100 tablets 00135-0199-08 180 tablets 00135-0199-01 240 tablets 00135-0199-07 240 tablets 00135-0199-09
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 0135-0199-02
Product NDC 0135-0199
11-digit billing NDC 00135019902
NCPDP billing unit EA — each (per item)
RxCUI 198750, 352178
UNII MRJ667KA5E
Application # M007
SPL Set ID d27f6742-2dcc-451e-b803-6ffe183038ec
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2010-02-01
Route ORAL
Dosage form TABLET
Substance METHYLCELLULOSE (4000 MPA.S)
GPI-14 46300010000330
GPI class Citrucel
GCN Seq No 003053
GCN 09522
HICL code 001341
Ingredient (HICL) Methylcellulose
HIC1 code D
Therapeutic class — broad (HIC1) Biliary System/Gastro-Intestinal System
HIC2 code D6
Therapeutic class — intermediate (HIC2) Drugs Acting Principally On The Colon
HIC3 code D6S
Therapeutic class — specific (HIC3) Laxatives And Cathartics
AHFS code 56:12.00.00
AHFS class Cathartics And Laxatives
FDB label name CITRUCEL 500 MG CAPLET
FDB brand name Citrucel
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 0135-0199-02 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00135-0199-02. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Bulk-forming laxatives class.

Drug family (ATC) Bulk-forming laxatives
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerHaleon US Holdings LLC
FDA applicationM007 (OTC MONOGRAPH DRUG)
Labeler code00135
First marketedFeb 2010
Product typeHuman Otc Drug
Portfolio403 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name CITRUCEL 500 MG CAPLET Ingredient Methylcellulose
🧪 What is this product?

Citrucel is an over-the-counter tablet taken by mouth that contains methylcellulose, a type of fiber. Methylcellulose is commonly used to increase stool bulk and promote bowel regularity in people experiencing occasional constipation. This product is marketed under the FDA's OTC monograph rules for fiber-based laxatives rather than as an individually reviewed drug application.

Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color orange
ShapeFreeform
ImprintCIT
Size19 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII L11K75P92J
    A mineral salt made from calcium and phosphate. It acts as a filler and binder in tablets to add bulk and help hold the medicine together in solid form.
  • UNII 2S7830E561
    Crospovidone is a synthetic polymer derived from povidone. It acts as a disintegrant, helping the tablet or capsule break apart quickly in the stomach so the active ingredient can be absorbed.
  • UNII H77VEI93A8
    A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII 7CVR7L4A2D
    A starch-derived carbohydrate produced by breaking down corn, potato, or tapioca starch. It functions as a filler and binder to give the medicine bulk and texture, and sometimes as a mild sweetener or texture enhancer in powders and tablets.
  • UNII FZ989GH94E
    Povidone is a synthetic polymer made from a plastic-like material. It acts as a binder to hold tablet ingredients together and as a disintegrant to help the tablet break apart in your stomach so the medicine can be absorbed.
  • UNII 368GB5141J
    A detergent and foaming agent derived from coconut or palm oil. In medications, it helps break down and mix oil and water-based ingredients, aids in tablet disintegration, and improves how the drug dissolves and spreads in the mouth or digestive system.

7 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescrospovidone, dibasic calcium phosphate, FD&C yellow no. 6 aluminum lake, magnesium stearate, maltodextrin, povidone, sodium lauryl sulfate

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 2 tablets 100 tablets 180 tablets 240 tablets 240 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Citrucel 500 mgthis 00135-0199-02 Haleon 100 tablets — — FDA listed —
Walgreens Fiber Therapy 500 mg 00363-1220-10 WALGREENS 100 tablets — — FDA listed —
Rite Aid Fiber Therapy 500 mg 11822-2221-00 RITE 100 tablets — — FDA listed —
Soluble Fiber 500 mg 41163-0288-16 United 100 tablets — — FDA listed —
meijer Fiber Therapy 500 mg 41250-0212-10 MEIJER 100 tablets — — FDA listed —
equate Fiber Therapy 500 mg 49035-0756-10 Wal-Mart 100 tablets — — FDA listed —
Goodsense Fiber 500 mg 50804-0364-16 GoodSense 100 tablets — — FDA listed —
CVS Fiber Therapy 500 mg 51316-0122-00 CVS 100 tablets — — FDA listed —
CDMA Fiber Therapy 500 mg 63868-0166-10 CHAIN 100 tablets — — FDA listed —
Best Choice Fiber Therapy 500 mg 63941-0122-10 BEST 100 tablets — — FDA listed —
Premier Value Fiber Therapy 500 mg 68016-0122-10 PHARMACY 100 tablets — — FDA listed —
DRx Choice Fiber Therapy 500 mg 68163-0122-00 RARITAN 100 tablets — — FDA listed —
Amazon Fiber Therapy 500 mg 72288-0122-00 AMAZON.COM 100 tablets — — FDA listed —
QUALITY CHOICE Fiber Therapy 500 mg 83324-0228-01 CHAIN 100 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2010
On the market since
Feb 2010
📍
2026
Currently FDA-listed
16 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Methylcellulose — the ingredient across all brands.

Top reported reactions

Nausea197
Diarrhoea186
Fatigue181
Constipation142
Dyspnoea133
Headache118
Dizziness116

Reporter sex

0 reports
Male · 32%
Female · 68%
Unknown · 0%

Serious outcomes

Death131
Disabling74
Life-threatening55
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 158 45
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
00135-0199-01 180 TABLET in 1 BOTTLE (0135-0199-01) 2010-02-01 Active
00135-0199-02 You're viewing this 100 TABLET in 1 BOTTLE (0135-0199-02) 2010-02-01 Active
00135-0199-06 2 TABLET in 1 POUCH (0135-0199-06) 2010-02-01 Active
00135-0199-07 240 TABLET in 1 BOTTLE (0135-0199-07) 2010-02-01 Active
00135-0199-08 50 POUCH in 1 CARTON (0135-0199-08) / 2 TABLET in 1 POUCH (0135-0199-06) 2010-02-01 Active
00135-0199-09 1 BOTTLE in 1 PACKAGE (0135-0199-09) / 240 TABLET in 1 BOTTLE 2017-02-15 Active

Pack size FAQ

What quantity is in NDC 00135-0199-02?
NDC 00135-0199-02 is a 100-count package — 100 tablet in 1 bottle.
What is the difference between NDC 00135-0199-02 and NDC 00135-0199-06?
Both are CITRUCEL methylcellulose 500 mg Tablet — the drug itself is identical. NDC 00135-0199-02 is the 100-count package, while NDC 00135-0199-06 is the 2 tablets package.
What NDC number is used to bill for this package of CITRUCEL methylcellulose 500 mg Tablet?
Bill NDC 00135-0199-02 — the 11-digit billing format is 00135019902. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 0135-0199-02, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 00135-0199-02, written without dashes as 00135019902. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 00135-0199-02, the first segment (00135) is the labeler code FDA assigned to Haleon US Holdings LLC; the middle segment (0199) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (02) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Haleon US Holdings LLC. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 5 other package presentations of this same product, including 2 tablets (00135-0199-06), 100 tablets (00135-0199-08), 180 tablets (00135-0199-01). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Haleon US Holdings LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 16 words ▾

Uses • relieves occasional constipation (irregularity) • generally produces a bowel movement in 12- 72 hours

⏱️ Dosage and Administration 105 words ▾

Directions Take this product (child or adult dose) with at least 8 ounces (a full glass) of water or other fluid. Taking this product without enough liquid may cause choking. See choking warning.

Age Dose Maximum Dose adults & children 12 years of age and over start with 2 caplets. Increase as needed up to 6 times per day. do not exceed 12 caplets per day children 6 - 11 years of age start with 1 caplet. Increase as needed up to 6 times per day. do not exceed 6 caplets per day children under 6 years of age consult a physician consult a physician

⚠️ Warnings 128 words ▾

Warnings Choking: taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking. Do not take this product if you have difficulty in swallowing. If you experience chest pain, vomiting, or difficulty in swallowing or breathing after taking this product, seek immediate medical attention.

Ask a doctor before use if you have • a sudden change in bowel habits that persists for two weeks • abdominal pain, nausea or vomiting Stop use and ask a doctor if • constipation lasts more than 7 days • you have rectal bleeding These could be signs of a serious condition. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 10 words ▾

Active ingredient (in each caplet) Methylcellulose (a non-allergenic fiber) 500mg

🧪 Inactive Ingredients 19 words ▾

Inactive ingredients crospovidone, dibasic calcium phosphate, FD&C yellow no. 6 aluminum lake, magnesium stearate, maltodextrin, povidone, sodium lauryl sulfate

🎯 Purpose 4 words ▾

Purpose Bulk-forming fiber laxative

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 00135-0196-02 · Haleon 00135-0200-01 · Haleon →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.