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Rite Aid Fiber Therapy Methylcellulose 500 mg Tablet, 100-count — NDC 11822-2221-00 package photo

Rite Aid Fiber Therapy Methylcellulose 500 mg Tablet, 100-count

by RITE AID CORPORATION · 100 TABLET in 1 BOTTLE (11822-2221-0)
NDC 11822-2221-00
🏷️ FDA NDC (as labeled) 11822-2221-0 billing pads the package segment with a zero
This package
Contains100-count Pack sizes2 compare ↓
Also comes in: 200 tablets 11822-2221-02
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 11822-2221-0
Product NDC 11822-2221
11-digit billing NDC 11822222100
RxCUI 198750
UNII MRJ667KA5E
UPC 0011822318303, 0011822333818
Application # M007
SPL Set ID e50cea80-c020-4b85-b61f-d053f11f479b
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2019-03-12
Route ORAL
Dosage form TABLET
Substance METHYLCELLULOSE (4000 MPA.S)
Why two NDCs? The FDA registers this code as 11822-2221-0 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 11822-2221-00. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Bulk-forming laxatives class.

Drug family (ATC) Bulk-forming laxatives
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerRITE AID CORPORATION
FDA applicationM007 (OTC MONOGRAPH DRUG)
Labeler code11822
First marketedMar 2019
Product typeHuman Otc Drug
Portfolio326 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

Rite Aid Fiber Therapy is an over-the-counter tablet taken by mouth that contains methylcellulose, a type of bulk-forming fiber. Methylcellulose is commonly used to help promote regularity and relieve occasional constipation by absorbing water in the intestines and forming a soft, bulky stool. This product is marketed as an OTC monograph drug, meaning it follows FDA's established rules for over-the-counter fiber supplements rather than being individually approved through a new drug application.

Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color Orange
ShapeCapsule
ImprintRP122
Size19 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 200 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Citrucel 500 mg 00135-0199-01 Haleon 180 tablets — — FDA listed —
Walgreens Fiber Therapy 500 mg 00363-1220-10 WALGREENS 100 tablets — — FDA listed —
Rite Aid Fiber Therapy 500 mgthis 11822-2221-00 RITE 100 tablets — — FDA listed —
Soluble Fiber 500 mg 41163-0288-16 United 100 tablets — — FDA listed —
meijer Fiber Therapy 500 mg 41250-0212-10 MEIJER 100 tablets — — FDA listed —
equate Fiber Therapy 500 mg 49035-0756-10 Wal-Mart 100 tablets — — FDA listed —
Goodsense Fiber 500 mg 50804-0364-16 GoodSense 100 tablets — — FDA listed —
CVS Fiber Therapy 500 mg 51316-0122-00 CVS 100 tablets — — FDA listed —
CDMA Fiber Therapy 500 mg 63868-0166-10 CHAIN 100 tablets — — FDA listed —
Best Choice Fiber Therapy 500 mg 63941-0122-10 BEST 100 tablets — — FDA listed —
Premier Value Fiber Therapy 500 mg 68016-0122-10 PHARMACY 100 tablets — — FDA listed —
DRx Choice Fiber Therapy 500 mg 68163-0122-00 RARITAN 100 tablets — — FDA listed —
Amazon Fiber Therapy 500 mg 72288-0122-00 AMAZON.COM 100 tablets — — FDA listed —
QUALITY CHOICE Fiber Therapy 500 mg 83324-0228-01 CHAIN 100 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2019
On the market since
Mar 2019
📍
2026
Currently FDA-listed
7 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
11822-2221-00 You're viewing this 100 TABLET in 1 BOTTLE (11822-2221-0) 2019-03-12 Active
11822-2221-02 200 TABLET in 1 BOTTLE (11822-2221-2) 2019-03-12 Active

You're viewing the smallest of 2 pack sizes for this product.

Pack size FAQ

What quantity is in NDC 11822-2221-00?
NDC 11822-2221-00 is a 100-count package — 100 tablet in 1 bottle.
What is the difference between NDC 11822-2221-00 and NDC 11822-2221-02?
Both are Rite Aid Fiber Therapy Methylcellulose 500 mg Tablet — the drug itself is identical. NDC 11822-2221-00 is the 100-count package, while NDC 11822-2221-02 is the 200 tablets package.
What NDC number is used to bill for this package of Rite Aid Fiber Therapy Methylcellulose 500 mg Tablet?
Bill NDC 11822-2221-00 — the 11-digit billing format is 11822222100. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 11822-2221-0, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 11822-2221-00, written without dashes as 11822222100. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 11822-2221-00, the first segment (11822) is the labeler code FDA assigned to RITE AID CORPORATION; the middle segment (2221) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (00) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by RITE AID CORPORATION. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 200 tablets (11822-2221-02). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
RITE AID CORPORATION is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 167 words ▾

Uses ▪ helps restore and maintain regularity ▪ relieves constipation (irregularity) ▪ for constipation associated with other bowel disorders like IBS when recommended by a doctor ▪ generally produces a bowel movement in 12-72 hours Warnings Choking : Taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking. Do not take this product if you have difficulty in swallowing. If you experience chest pain, vomiting or difficulty in swallowing or breathing after taking this product, seek immediate medical attention.

Ask a doctor before use if you have ▪ a sudden change in bowel habits that persists over a period of 2 weeks ▪ abdominal pain, nausea or vomiting Stop use and ask a doctor if ▪ constipation lasts more than 7 days ▪ You have rectal bleeding. These could be as serious condition. Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222.

⏱️ Dosage and Administration 105 words ▾

Directions Take this product (child or adult dose) with at least 8 ounces (a full glass) of water or other fluid. Taking this product without enough liquid may cause choking. See choking warning.

AGE DOSE MAXIMUM DOSE adults & children 12 years of age and over Start with 2 caplets. Increase as needed up to 6 times per day. Do not exceed 12 caplets per day Children 6 - 11 years of age Start with 1 caplets.

Increase as needed up to 6 times per day. Do not exceed 6 caplets per day children under 6 years of age Consult a physician Consult a physician

⚠️ Warnings 132 words ▾

Warnings Choking : Taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking. Do not take this product if you have difficulty in swallowing. If you experience chest pain, vomiting or difficulty in swallowing or breathing after taking this product, seek immediate medical attention.

Ask a doctor before use if you have ▪ a sudden change in bowel habits that persists over a period of 2 weeks ▪ abdominal pain, nausea or vomiting Stop use and ask a doctor if ▪ constipation lasts more than 7 days ▪ You have rectal bleeding. These could be as serious condition. Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222.

🧪 Active Ingredient 7 words ▾

Active ingredient (in each caplet) Methylcellulose 500mg

🧪 Inactive Ingredients 21 words ▾

Inactive ingredients adipic acid, calcium carbonate, crospovidone, FD&C yellow no. 6 aluminum lake, magnesium stearate, maltodextrin, microcrystalline cellulose, polysorbate 80, silica.

🎯 Purpose 7 words ▾

Purpose Bulk-forming fiber laxative (a non-allergenic fiber)

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 11822-2219-00 · Rite 11822-2260-02 · Rite →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.