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AllergyCalm ONION, AMBROSIA ARTEMISIIFOLIA, EUPHRASIA STRICTA, HISTAMINE DIHYDROCHLORIDE, SCHOENOCAULON OFFICINALE SEED, SOLIDAGO VIRGAUREA FLOWERING TOP 5 [hp_C]/1; 9 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1 Tablet, 120-count — NDC 00220-9307-29 package photo

AllergyCalm ONION, AMBROSIA ARTEMISIIFOLIA, EUPHRASIA STRICTA, HISTAMINE DIHYDROCHLORIDE, SCHOENOCAULON OFFICINALE SEED, SOLIDAGO VIRGAUREA FLOWERING TOP 5 [hp_C]/1; 9 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1 Tablet, 120-count

by Boiron · 6 BLISTER PACK in 1 BOX (0220-9307-29) / 20 TABLET in 1 BLISTER PACK
NDC 00220-9307-29
🏷️ FDA NDC (as labeled) 0220-9307-29 billing pads the labeler segment with a zero
This package
Contains120-count Pack sizes2 compare ↓
Also comes in: 60 tablets 00220-9307-04
OTC On market Non-controlled
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 0220-9307-29
Product NDC 0220-9307
11-digit billing NDC 00220930729
UNII C9642I91WL, 3POA0Q644U, 6NAF1689IO, 492225Q21H, 5405K23S50, 9W34L2CQ9A
SPL Set ID d9a509d9-15c8-20bb-e053-2a95a90a3edd
Established class (EPC) Non-Standardized Food Allergenic Extract
Physiologic effect Increased Histamine Release; Cell-mediated Immunity
Chemical class Allergens; Dietary Proteins; Vegetable Proteins
DEA schedule Non-controlled
Marketing category UNAPPROVED HOMEOPATHIC
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2022-03-01
Route ORAL
Dosage form TABLET
Substance EUPHRASIA STRICTA; HISTAMINE DIHYDROCHLORIDE; SCHOENOCAULON OFFICINALE SEED; ONION; SOLIDAGO VIRGAUREA FLOWERING TOP; AMBROSIA ARTEMISIIFOLIA
Why two NDCs? The FDA registers this code as 0220-9307-29 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00220-9307-29. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerBoiron
Labeler code00220
First marketedMar 2022
Product typeHuman Otc Drug
Portfolio2,039 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

AllergyCalm is an unapproved homeopathic tablet taken by mouth. It contains six plant-derived ingredients (onion, ragweed, eyebright, goldenrod, sabadilla seed, and histamine dihydrochloride) that are used in homeopathic tradition to address allergy symptoms. Homeopathic products are marketed based on historical use rather than FDA evaluation for effectiveness.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color white
ShapeRound
ImprintBoiron
Size9 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII M28OL1HH48
    Croscarmellose sodium is a plant-based substance derived from cellulose. It acts as a disintegrant, helping tablets and capsules break down quickly in the digestive system so the medicine can be absorbed.
  • UNII J2B2A4N98G
    Lactose is a natural sugar derived from milk. In medications, it serves as a filler and binder to add bulk and help hold tablet or capsule ingredients together during manufacturing.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.

3 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescroscarmellose sodium, lactose, magnesium stearate

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 60 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
AllergyCalm 5 [hp_C]/1; 9 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]this 00220-9307-29 Boiron 120 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2022
On the market since
Mar 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
00220-9307-04 3 BLISTER PACK in 1 BOX (0220-9307-04) / 20 TABLET in 1 BLISTER PACK 2022-03-01 Active
00220-9307-29 You're viewing this 6 BLISTER PACK in 1 BOX (0220-9307-29) / 20 TABLET in 1 BLISTER PACK 2022-08-01 Active

Pack size FAQ

What quantity is in NDC 00220-9307-29?
NDC 00220-9307-29 is a 120-count package — 6 blister pack in 1 box / 20 tablet in 1 blister pack.
What is the difference between NDC 00220-9307-29 and NDC 00220-9307-04?
Both are AllergyCalm ONION, AMBROSIA ARTEMISIIFOLIA, EUPHRASIA STRICTA, HISTAMINE DIHYDROCHLORIDE, SCHOENOCAULON OFFICINALE SEED, SOLIDAGO VIRGAUREA FLOWERING TOP 5 [hp_C]/1; 9 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1 Tablet — the drug itself is identical. NDC 00220-9307-29 is the 120-count package, while NDC 00220-9307-04 is the 60 tablets package.
What NDC number is used to bill for this package of AllergyCalm ONION, AMBROSIA ARTEMISIIFOLIA, EUPHRASIA STRICTA, HISTAMINE DIHYDROCHLORIDE, SCHOENOCAULON OFFICINALE SEED, SOLIDAGO VIRGAUREA FLOWERING TOP 5 [hp_C]/1; 9 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1 Tablet?
Bill NDC 00220-9307-29 — the 11-digit billing format is 00220930729. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product Homeopathic listing

About homeopathic listings

AllergyCalm ONION, AMBROSIA ARTEMISIIFOLIA, EUPHRASIA STRICTA, HISTAMINE DIHYDROCHLORIDE, SCHOENOCAULON OFFICINALE SEED, SOLIDAGO VIRGAUREA FLOWERING TOP 5 [hp_C]/1; 9 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1; 5 [hp_C]/1 TABLET is listed under the homeopathic marketing category. An NDC listing in this category does not by itself establish FDA approval, and FDA does not evaluate homeopathic products for effectiveness. This page reports the listing data as published.

What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Homeopathic". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 0220-9307-29, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 00220-9307-29, written without dashes as 00220930729. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 00220-9307-29, the first segment (00220) is the labeler code FDA assigned to Boiron; the middle segment (9307) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (29) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Boiron. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 60 tablets (00220-9307-04). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Boiron is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 24 words ▾

Uses* temporarily relieves these symptoms of hay fever or other upper respiratory allergies: itchy and watery eyes sneezing itchy throat and nose runny nose

⏱️ Dosage and Administration 73 words ▾

Directions Children 6 to 12 years of age - At the onset of symptoms, dissolve 2 tablets in the mouth every 15 minutes for 1 hour. Then, dissolve 2 tablets in the mouth 3 times a day until symptoms are relieved. Children 2 to 6 years of age - Dissolve 2 tablets in 1 tablespoon of water for easier intake. Follow directions above. Children under 2 years of age - Ask a doctor.

⚠️ Warnings 1 words ▾

Warnings

🧪 Active Ingredient 69 words ▾

Active ingredients** (in each tablet) Allium cepa 5C HPUS (0.42 mg) Ambrosia artemisiaefolia 5C HPUS (0.42 mg) Euphrasia officinalis 5C HPUS (0.42 mg) Histaminum hydrochloricum 9C HPUS (0.42 mg) Sabadilla 5C HPUS (0.42 mg) (contains less than 10 -11 mg cevadine alkaloids) Solidago vigaurea 5C HPUS (0.42 mg) The letters "HPUS" indicate that the components in this product are officially monographed in the Homeopathic Pharmacopoeia of the United States.

🧪 Inactive Ingredients 5 words ▾

croscarmellose sodium, lactose, magnesium stearate

🎯 Purpose 75 words ▾

Purpose* Allium cepa 5C HPUS (0.42 mg) ... Relieves runny nose associated with allergies Ambrosia artemisiaefolia 5C HPUS (0.42 mg) ... Relieves symptoms associated with hay fever Euphrasia officinalis 5C HPUS (0.42 mg) ...

Relieves burning, irritated eyes Histaminum hydrochloricum 9C HPUS (0.42 mg) ... Relieves symptoms of allergic reactions Sabadilla 5C HPUS (0.42 mg) ... Relieves sneezing and itchy throat associated with allergies Solidago vigaurea 5C HPUS (0.42 mg) ...

Relieves abundant nasal discharge

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 00220-9306-04 · Boiron 00220-9308-42 · Boiron →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.