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Tucks Triple Relief Hemorrhoidal WHITE PETROLATUM, GLYCERIN, PRAMOXINE HYDROCHLORIDE, and PHENYLEPHRINE HYDROCHLORIDE 16 g/100g; 15 g/100g; 1 g/100g; .25 g/100g Cream — NDC 10157-2126-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Tucks Triple Relief Hemorrhoidal WHITE PETROLATUM, GLYCERIN, PRAMOXINE HYDROCHLORIDE, and PHENYLEPHRINE HYDROCHLORIDE 16 g/100g; 15 g/100g; 1 g/100g; .25 g/100g Cream — NDC 10157-2126-1 (Billing 10157-2126-01)

by Blistex Inc. · 1 TUBE, WITH APPLICATOR in 1 CARTON / 26 g in 1 TUBE, WITH APPLICATOR

This is a package of Tucks Triple Relief Hemorrhoidal WHITE PETROLATUM, GLYCERIN, PRAMOXINE HYDROCHLORIDE, and PHENYLEPHRINE HYDROCHLORIDE 16 g/100g; 15 g/100g; 1 g/100g; .25 g/100g Cream from Blistex Inc., marketed since Jan 2025 and currently FDA-listed. It is this product's only package size.

NDC 10157-2126-01
🏷️ FDA NDC (as labeled) 10157-2126-1 billing pads the package segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 10157-2126-1 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
10157 labeler · 2126 product · 1 package
Package marketed since
Jan 6, 2025
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 1015721261 5
FDA record last changed
Aug 27, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 10157-2126-1
Product NDC 10157-2126
11-digit billing NDC 10157212601
RxCUI 2701523
UNII B6E5W8RQJ4, PDC6A3C0OX, 88AYB867L5, 04JA59TNSJ
Application # M015
SPL Set ID bf892e90-2d9b-4fa0-8ee4-8a2736be6c30
Established class (EPC) Non-Standardized Chemical Allergen
Physiologic effect Increased Histamine Release; Cell-mediated Immunity; Increased IgG Production
Chemical class Allergens; Glycerol
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2025-01-06
Route TOPICAL
Dosage form CREAM
Substance WHITE PETROLATUM; GLYCERIN; PRAMOXINE HYDROCHLORIDE; PHENYLEPHRINE HYDROCHLORIDE
Quick answers
  • RxCUI (RxNorm): 2701523
Why two NDCs? The FDA registers this code as 10157-2126-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 10157-2126-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Local anesthetics class.

Drug family (ATC) Local anesthetics, Anesthetics for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

🧪 What is this product?

Tucks Triple Relief Hemorrhoidal is a topical cream sold as an over-the-counter monograph product for hemorrhoid discomfort. It contains white petrolatum and glycerin, which function as lubricants and skin protectants. Pramoxine hydrochloride is a local anesthetic typically used to numb minor pain and itching, while phenylephrine hydrochloride is a decongestant that narrows blood vessels in the area. This combination is commonly applied directly to the affected area to help ease hemorrhoid-related symptoms.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
10157-2126-01 You're viewing this Main listing 1 TUBE, WITH APPLICATOR in 1 CARTON / 26 g in 1 TUBE, WITH APPLICATOR 2025-01-06 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Tucks Triple Relief Hemorrhoidal 16 g/100g; 15 g/100g; 1 g/100g; .25 g/100gthis 10157-2126-01 Blistex 1 tube — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2025
On the market since
Jan 2025
📍
2026
Currently FDA-listed
1 year listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 1QR1QRA9BU
    A fatty alcohol derived from peanut oil or made synthetically. It serves as an emollient and thickener in creams and ointments, helping create smooth texture and improve product consistency.
  • UNII 6JVW35JOOJ
    Arachidyl glucoside is a plant-derived emulsifier and skin-conditioning agent made from arachidyl alcohol and glucose. It helps mix oil and water-based ingredients together in formulations and improves product texture and spreadability.
  • UNII 9G1OE216XY
    Docosanol is a waxy, fatty alcohol derived from plant sources. It acts as an emollient and thickener in topical medicines, helping to soften the skin and improve product texture and stability.
  • UNII 7FLD91C86K
    Edetate disodium is a chemical compound that binds and removes certain metal ions. In medicines, it acts as a preservative and stabilizer by preventing metals like calcium from interfering with the product's shelf life and consistency.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII NT00Y05A2V
    A liquid extract from witch hazel plant leaves and twigs. It's used in topical products as an astringent agent and to help deliver other active ingredients into the skin.
  • UNII XOF597Q3KY
    A refined form of wax made from petroleum, microcrystalline wax is used in medicines as a coating agent, binder, and hardening ingredient. It helps give tablets and capsules their shape and protective outer layer.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII 46P231IQV8
    A synthetic emulsifier derived from glycerin and fatty acids. It helps blend oil and water-based ingredients together in cosmetic and pharmaceutical formulations to create stable, uniform products.
  • UNII CAL22UVI4M
    A synthetic emulsifier derived from sorbitol and fatty acids. It helps mix oil and water-based ingredients together and improves the texture and stability of the medicine.
  • UNII 01S2G2C1E4
    Sorbitan isostearate is an emulsifier derived from sorbitol and isostearic acid. It helps mix oil and water-based ingredients together and keeps them blended throughout the medicine's shelf life.
  • UNII A68S9UI39D
    Stearyl behenate is a wax-like substance made from plant or animal fats. It serves as a lubricant and glidant in tablets and capsules, helping ingredients flow smoothly during manufacturing and preventing sticking.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII 2ZA36H0S2V
    Beeswax is a natural wax produced by honeybees. In medicines, it works as a coating agent and thickener to control how fast the drug dissolves and improve the product's texture and appearance.

14 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesarachidyl alcohol, arachidyl glucoside, beeswax, behenyl alcohol, disodium EDTA, ethylhexylglycerin, hamamelis virginiana (witch hazel) water, microcrystalline wax, phenoxyethanol, polyglyceryl-3 diisostearate, polysorbate 60, purified water, sorbitan isostearate, stearyl behenate

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerBlistex Inc.
FDA applicationM015 (OTC MONOGRAPH DRUG)
Labeler code10157
First marketedJan 2025
Product typeHuman Otc Drug
Portfolio17 products on file

More NDCs from Blistex Inc. labeler code 10157

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Ask a Doctor Before Use If 📄 Ask a Doctor or Pharmacist Before Use If 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 66 words ▾

Uses for the temporary relief of pain, soreness, or burning helps relieve the local itching and discomfort associated with hemorrhoids temporarily shrinks hemorrhoidal tissue temporarily provides a coating for relief of anorectal discomforts temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful temporarily forms a protective coating over inflamed tissues to help prevent drying of tissues may provide a cooling sensation

⏱️ Dosage and Administration 123 words ▾

Directions Adults: when practical, clean the affected area with mild soap and warm water and rinse thoroughly gently dry by patting or blotting with toilet tissue or a soft cloth before application of this product when first opening the tube, remove foil seal. Do not use if foil seal is broken. apply externally or in the lower portion of the anal canal only apply externally to the affected area up to 4 times daily for application in the lower anal canal, remove cover from dispensing cap. Attach dispensing cap to tube.

Lubricate dispensing cap well, then gently insert dispensing cap partially into the anus. thoroughly clean dispensing cap after each use and replace cover children under 12 years of age: ask a doctor

⚠️ Warnings 162 words ▾

Warnings For external use only Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression. When using this product do not exceed the recommended daily dosage unless directed to do so by a doctor do not put directly in the rectum by using fingers or any mechanical device or applicator Stop use and ask a doctor if bleeding occurs condition worsens or does not improve within 7 days allergic reactions develop due to ingredients in this product the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 3 words ▾

Other information www.tucks.com

🧪 Active Ingredient 23 words ▾

Active ingredients Purpose Glycerin 15% (w/w) Protectant Phenylephrine HCl 0.25% (w/w) Vasoconstrictor Pramoxine HCl 1.0% (w/w) Local anesthetic White Petrolatum 16% (w/w) Protectant

🧪 Inactive Ingredients 30 words ▾

Inactive ingredients arachidyl alcohol, arachidyl glucoside, beeswax, behenyl alcohol, disodium EDTA, ethylhexylglycerin, hamamelis virginiana (witch hazel) water, microcrystalline wax, phenoxyethanol, polyglyceryl-3 diisostearate, polysorbate 60, purified water, sorbitan isostearate, stearyl behenate

🎯 Purpose 23 words ▾

Active ingredients Purpose Glycerin 15% (w/w) Protectant Phenylephrine HCl 0.25% (w/w) Vasoconstrictor Pramoxine HCl 1.0% (w/w) Local anesthetic White Petrolatum 16% (w/w) Protectant

📄 Ask a Doctor Before Use If 26 words ▾

Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland

📄 Ask a Doctor or Pharmacist Before Use If 21 words ▾

Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression.

📄 When Using This Product 35 words ▾

When using this product do not exceed the recommended daily dosage unless directed to do so by a doctor do not put directly in the rectum by using fingers or any mechanical device or applicator

📄 Stop Use and Ask a Doctor If 46 words ▾

Stop use and ask a doctor if bleeding occurs condition worsens or does not improve within 7 days allergic reactions develop due to ingredients in this product the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase

🤰 If Pregnant or Breast-Feeding 10 words ▾

If pregnant or breast-feeding, ask a health professional before use.

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Package Label / Principal Display Panel 62 words ▾

PRINCIPAL DISPLAY PANEL - 26 g Tube Carton NEW TUCKS ® TRIPLE RELIEF HEMORRHOIDAL CREAM Hemorrhoidal Cream MAXIMUM STRENGTH PAIN RELIEF helps relieve pain from burning, itching & discomfort shrinks swollen hemorrhoidal tissue cools & soothes sensitive areas BRAND USED BY HOSPITALS with WITCH HAZEL Net Wt. 0.9 oz. (26 g) - 1 tube PRINCIPAL DISPLAY PANEL - 26 g Tube Carton

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Blistex Inc.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Blistex Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 10157-2125-01 · Blistex 10157-2127-01 · Blistex →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.