Home › NDC Lookup › Ingredients › Ensulizole, Octinoxate, Octisalate, Tita... › 10356-0323-25
Eucerin Daily Protection Face Ensulizole, Octinoxate, Octisalate, Titanium Dioxide, Zinc Oxide 2 g/100mL; 7.5 g/100mL; 4.5 g/100mL; 2.4 g/100mL; 4.8 g/100mL Lotion, 5 mL — NDC 10356-0323-25 package photo

Eucerin Daily Protection Face Ensulizole, Octinoxate, Octisalate, Titanium Dioxide, Zinc Oxide 2 g/100mL; 7.5 g/100mL; 4.5 g/100mL; 2.4 g/100mL; 4.8 g/100mL Lotion, 5 mL

by Beiersdorf Inc · 5 mL in 1 TUBE (10356-323-25)
NDC 10356-0323-25
🏷️ FDA NDC (as labeled) 10356-323-25 billing pads the product segment with a zero
This package
Contains5 mL Pack sizes4 compare ↓
Also comes in: 4 ml 10356-0323-27 30 ml 10356-0323-04 118 ml 10356-0323-11
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 10356-323-25
Product NDC 10356-323
11-digit billing NDC 10356032325
UNII 9YQ9DI1W42, 4Y5P7MUD51, 4X49Y0596W, 15FIX9V2JP, SOI2LOH54Z
Application # M020
SPL Set ID 76403f03-aee9-4c0b-b331-f79b6953118c
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2015-08-12
Route TOPICAL
Dosage form LOTION
Substance ENSULIZOLE; OCTINOXATE; OCTISALATE; TITANIUM DIOXIDE; ZINC OXIDE
Why two NDCs? The FDA registers this code as 10356-323-25 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 10356-0323-25. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerBeiersdorf Inc
FDA applicationM020 (OTC MONOGRAPH DRUG)
Labeler code10356
First marketedAug 2015
Product typeHuman Otc Drug
Portfolio105 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

Eucerin Daily Protection Face Lotion is a topical sunscreen product available over the counter as an OTC monograph drug. It contains five active ingredients that work together as UV filters: ensulizole, octinoxate, octisalate, titanium dioxide, and zinc oxide. These ingredients are typically used to absorb or reflect ultraviolet light from the sun. The lotion is applied to the face to help protect skin from UV exposure.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII TR046Y3K1G
    A liquid alcohol derived from petroleum or plant sources. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
  • UNII A9EJ3J61HQ
    A synthetic liquid derived from benzoic acid and long-chain alcohols. It functions as a solvent and penetration enhancer in topical formulations, helping active ingredients dissolve and absorb into the skin.
  • UNII LMI26O6933
    Alumina is a white powder form of aluminum oxide. It's used as a filler to add bulk to tablets and capsules, and sometimes as a thickening or anti-caking agent in powdered formulations.
  • UNII 2DMT128M1S
    A waxy solid derived from plant or animal sources. It acts as an emulsifier to blend oil and water components, and also thickens the medicine to give it the right texture and consistency.
  • UNII 936JST6JCN
    Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
  • UNII ISE9I7DNUG
    Cocoglycerides are fatty substances derived from coconut oil. They act as emulsifiers and solubilizers in medicines, helping blend water and oil-based ingredients together and improve how the body absorbs certain drugs.
  • UNII NMQ347994Z
    Cyclomethicone is a silicone-based fluid that acts as a lubricant and solvent in medicines. It helps products flow smoothly, reduces friction between particles, and aids in even distribution of active ingredients.
  • UNII 92RU3N3Y1O
    Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
  • UNII 420IP921MB
    A chelating agent derived from edetic acid that binds to metals in the formulation. It helps stabilize the medicine by preventing metal ions from causing breakdown or discoloration.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 230OU9XXE4
    A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
  • UNII 33X04XA5AT
    Lactic acid is a naturally occurring organic acid derived from milk or plant sources. It lowers and maintains pH in formulations, helps preserve the product, and can enhance ingredient stability and absorption.
  • UNII N8F53B3R4R
    A synthetic humectant and solvent derived from propane. It draws and holds moisture in the formulation, helping keep the medicine stable and improving texture or flow in liquid and semi-solid products.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII YRC528SWUY
    A waxy emulsifier made from plant-derived fatty alcohols. It helps blend oil and water-based ingredients together and improves how the medicine spreads and absorbs.
  • UNII 4ERD2076EF
    A synthetic liquid made by combining polyethylene glycol with castor oil. It works as a solubilizer and emulsifier to help mix water and oil-based ingredients, keeping the medicine uniform throughout the product.
  • UNII 7ZBS06BH4B
    A synthetic surfactant derived from coconut or palm oil. It helps other ingredients blend evenly throughout the medicine and improves how the product spreads or dissolves, acting as an emulsifier and detergent.
  • UNII 55X04QC32I
    A strong alkaline chemical used to adjust and maintain the pH balance of liquid medicines. It helps keep the medicine stable and ensures it stays effective during storage.
  • UNII TU7HW0W0QT
    A salt derived from lactic acid, sodium lactate acts as a buffer and pH stabilizer in medicines. It helps maintain the product's acidity level and can also serve as a humectant to retain moisture.
  • UNII FZ07E4LW2M
    A silane compound used as a glidant and anti-caking agent in solid dosage forms. It reduces friction between particles, helping powders and tablets flow smoothly during manufacturing and improving tablet release from molds.
  • UNII KFR5QEN0N9
    A synthetic plastic polymer that helps form a protective film coating on the medicine. It's used as a binder and film-former to hold the tablet or capsule together and control how quickly the drug dissolves.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII TTV12P4NEE
    Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.

23 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesInactive Ingredients Water, Glycerin, C12-15 Alkyl Benzoate, Dimethicone, Cyclomethicone, Methylpropanediol, Cetearyl Alcohol, Cetyl Alcohol, Ceteareth-20, Phenoxyethanol, Glyceryl Stearate SE, Sodium Lactate, Lactic Acid, 1,2-Hexanediol, Hydrogenated Coco-Glycerides, VP/Hexadecene Copolymer, Xanthan Gum, PEG-40 Castor Oil, Sodium Hydroxide, Trisodium EDTA, Alumina, Sodium Cetearyl Sulfate, Triethoxycaprylylsilane, Simethicone

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 4 ml 30 ml 118 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Eucerin Daily Protection Face 2 g/100mL; 7.5 g/100mL; 4.5 g/100mL; 2.4 g/100mL; 4.8 g/100mLthis 10356-0323-25 Beiersdorf 5 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2015
On the market since
Aug 2015
📍
2026
Currently FDA-listed
11 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Ensulizole, Octinoxate, Octisalate, Titanium Dioxide, Zinc Oxide — the ingredient across all brands.

Top reported reactions

Dysphagia1
Dyspnoea1
Erythema1
Pain1
Pruritus1
Swelling1
Urticaria1

Reporter sex

2 reports
Female · 100%

Serious outcomes

Life-threatening1
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
10356-0323-04 30 mL in 1 TUBE (10356-323-04) 2015-08-12 Active
10356-0323-11 118 mL in 1 BOTTLE (10356-323-11) 2015-08-12 Active
10356-0323-25 You're viewing this 5 mL in 1 TUBE (10356-323-25) 2015-08-12 Active
10356-0323-27 4 mL in 1 PACKET (10356-323-27) 2019-08-12 Active

You're viewing one of 4 pack sizes for this product.

Pack size FAQ

What quantity is in NDC 10356-0323-25?
NDC 10356-0323-25 contains 5 mL — 5 ml in 1 tube.
What is the difference between NDC 10356-0323-25 and NDC 10356-0323-27?
Both are Eucerin Daily Protection Face Ensulizole, Octinoxate, Octisalate, Titanium Dioxide, Zinc Oxide 2 g/100mL; 7.5 g/100mL; 4.5 g/100mL; 2.4 g/100mL; 4.8 g/100mL Lotion — the drug itself is identical. NDC 10356-0323-25 is the 5 mL package, while NDC 10356-0323-27 is the 4 ml package.
What NDC number is used to bill for this package of Eucerin Daily Protection Face Ensulizole, Octinoxate, Octisalate, Titanium Dioxide, Zinc Oxide 2 g/100mL; 7.5 g/100mL; 4.5 g/100mL; 2.4 g/100mL; 4.8 g/100mL Lotion?
Bill NDC 10356-0323-25 — the 11-digit billing format is 10356032325. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 10356-323-25, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 10356-0323-25, written without dashes as 10356032325. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 10356-0323-25, the first segment (10356) is the labeler code FDA assigned to Beiersdorf Inc; the middle segment (0323) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (25) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Beiersdorf Inc. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 3 other package presentations of this same product, including 4 ml (10356-0323-27), 30 ml (10356-0323-04), 118 ml (10356-0323-11). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Beiersdorf Inc is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 32 words ▾

Uses • helps prevent sunburn • if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun.

⏱️ Dosage and Administration 100 words ▾

Directions For sunscreen use: • apply liberally 15 minutes before sun exposure • use a water resistant sunscreen if swimming or sweating • reapply at least every 2 hours • Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: • limit time in the sun, especially from 10 a.m.-2 p.m.• wear long-sleeved shirts, pants, hats, and sunglasses. • Children under 6 months of age: Ask a doctor

⚠️ Warnings 5 words ▾

Warnings For external use only

🧪 Active Ingredient 14 words ▾

Active ingredients Ensulizole 2% Octinoxate 7.5% Octisalate 4.5% Titanium Dioxide 2.4% Zinc Oxide 4.8%

🧪 Inactive Ingredients 43 words ▾

Inactive Ingredients Water, Glycerin, C12-15 Alkyl Benzoate, Dimethicone, Cyclomethicone, Methylpropanediol, Cetearyl Alcohol, Cetyl Alcohol, Ceteareth-20, Phenoxyethanol, Glyceryl Stearate SE, Sodium Lactate, Lactic Acid, 1,2-Hexanediol, Hydrogenated Coco-Glycerides, VP/Hexadecene Copolymer, Xanthan Gum, PEG-40 Castor Oil, Sodium Hydroxide, Trisodium EDTA, Alumina, Sodium Cetearyl Sulfate, Triethoxycaprylylsilane, Simethicone

🎯 Purpose 2 words ▾

Purpose Sunscreens

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 10356-0130-25 · Beiersdorf 10356-0328-31 · Beiersdorf →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.