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UNBLEMISH 30-Day Regimen SALICYLIC ACID, BENZOYL PEROXIDE, HOMOSALATE, OCTOCRYLENE, OCTISALATE, AVOBENZONE Kit — NDC 14222-2150-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

UNBLEMISH 30-Day Regimen SALICYLIC ACID, BENZOYL PEROXIDE, HOMOSALATE, OCTOCRYLENE, OCTISALATE, AVOBENZONE Kit — NDC 14222-2150-1 (Billing 14222-2150-01)

by Rodan & Fields · 1 KIT in 1 CARTON * 20 mL in 1 BOTTLE, PUMP * 15 mL in 1 TUBE * 65 mL in 1 TUBE

This is a package of UNBLEMISH 30-Day Regimen SALICYLIC ACID, BENZOYL PEROXIDE, HOMOSALATE, OCTOCRYLENE, OCTISALATE, AVOBENZONE Kit from Rodan & Fields, marketed since Jan 2026 and currently FDA-listed. It is this product's only package size.

NDC 14222-2150-01
🏷️ FDA NDC (as labeled) 14222-2150-1 billing pads the package segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 14222-2150-1 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
14222 labeler · 2150 product · 1 package
Package marketed since
Jan 1, 2026
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Barcode (UPC-A, from the NDC)
3 1422221501 3
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 14222-2150-1
Product NDC 14222-2150
11-digit billing NDC 14222215001
RxCUI 200009, 865105
Application # M006
SPL Set ID e9a52ccc-6ba0-4417-86cc-b2116a5b8d26
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2026-01-01
Route TOPICAL
Dosage form KIT
Quick answers
  • RxCUI (RxNorm): 200009
Why two NDCs? The FDA registers this code as 14222-2150-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 14222-2150-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Peroxides class.

Drug family (ATC) Peroxides
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

🧪 What is this product?

This is a 30-day topical skincare kit marketed as an over-the-counter monograph product. It contains salicylic acid and benzoyl peroxide, which are commonly used in acne-fighting regimens to help reduce blemishes and oil buildup. The kit also includes three UV filters (homosalate, octocrylene, and octisalate) and avobenzone, which are typical sunscreen ingredients that function to protect skin from ultraviolet light exposure.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
14222-2150-01 You're viewing this Main listing 1 KIT in 1 CARTON * 20 mL in 1 BOTTLE, PUMP * 15 mL in 1 TUBE * 65 mL in 1 TUBE 2026-01-01 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
UNBLEMISH 30-Day Regimenthis 14222-2150-01 Rodan 1 kit — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2026
On the market since
Jan 2026
📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

From the label’s inactive-ingredient sectionacrylates copolymer, water, cetyl alcohol, citronellol, cocamidopropyl betaine, coconut acid, colloidal sulfur, distearyl phthalic acid amide, ethylhexylglycerin, ext. violet 2 (Cl 60730), fragrance/parfum, geraniol, glycerin, hydrogenated polyisobutene, lauric acid, lauryl glucoside, limonene, linalool, myristic acid, phenoxyethanol, phytosteryl/octyldodecyl lauroyl glutamate, potassium cocoate, potassium cocoyl glycinate, potassium hydroxide, propanediol, propylene glycol, red 33 (Cl 17200), sodium chloride, sodium cocoyl isethionate, sodium isethionate, titanium dioxide (Cl 77891), tocopherol, xanthan gum benzyl alcohol, butyloctyl salicylate, C12-15 alkyl benzoate, dimethicone crosspolymer, dimethicone/bis-isobutyl PPG-20 crosspolymer, divinyldimethicone/dimethicone/phenylsilsesquioxane crosspolymer, ethylhexylglycerin, glycerin, isododecane, linoleic acid, linolenic acid, oleic acid, palmitic acid, polymethylsilsesquioxane, polysilicone-22, silica, silica silylate, stearic acid, tocopherol, vinyl dimethicone/methicone silsesquioxane crosspolymer allantoin, aloe barbadensis leaf juice, aminomethyl propanol, aqua/eau/water, benzyl alcohol, BHT, biosaccharide gum-1, C13-14 isoalkane, carbomer, ceramide AP, ceramide EOP, ceramide NP, chamomilla recutita (matricaria) flower extract, cholesterol, citronellol, corn starch modified, disodium EDTA, ethoxydiglycol, ethylhexylglycerin, fragrance/parfum, geraniol, glycerin, laureth-7, leuconostoc/radish root ferment filtrate, limonene, linalool, niacinamide, panthenol, PEG-7 glyceryl cocoate, phenoxyethanol, phytosphingosine, polyacrylamide, punica granatum fruit extract, sodium lauroyl lactylate, xanthan gum, yucca glauca root extract

This is label-wide narrative text, not a normalized exact-product ingredient list. A label can cover multiple strengths or packages.

Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerRodan & Fields
FDA applicationM006 (OTC MONOGRAPH DRUG)
Labeler code14222
First marketedJan 2026
Product typeHuman Otc Drug
Portfolio29 products on file

More NDCs from Rodan & Fields labeler code 14222

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Other Information 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 145 words ▾

Uses for the treatment of acne helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads Warnings For external use only When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. rinse right away with water if it gets in eyes Stop use and ask a doctor if skin irritation occurs or gets worse Keep out of reach of children. If swallowed, get medical help right away.

Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun

Uses for the treatment of acne helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads

⏱️ Dosage and Administration ~1 min read ▾

Directions wet skin with lukewarm water. Using fingertips, apply a thin, even layer and massage over entire face for 30-60 seconds, avoiding all contact with eyes. rinse thoroughly; pat dry because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce application to once a day or every other day

Directions apply liberally over face at least 15 minutes before sun exposure reapply at least every 2 hours use a water-resistant sunscreen if swimming or sweating Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF value of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 AM - 2 PM wear long-sleeve shirts, pants, hats and sunglasses children under 6 months: ask a doctor

Directions clean the skin thoroughly before applying this product dispense 1-2 pumps from each side. Blend product evenly. cover the entire affected area with a thin even layer one to three times daily, as needed because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce application to once a day or every other day do not rinse product off face if going outside, apply sunscreen after using this product.

If irritation or sensitivity develops, stop use of both products and ask a doctor. wash hands after application to help avoid staining fabrics

⚠️ Warnings 191 words ▾

Warnings For external use only Do not use on damaged or broken skin When using this product keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if if rash occurs Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Warnings For external use only Do not use if you have very sensitive skin are sensitive to benzoyl peroxide When using this product skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product Stop use and ask a doctor if irritation becomes severe Keep out of reach of children.

If swallowed, get medical help right away.

🧪 Active Ingredient 20 words ▾

Active ingredient Salicylic acid 0.5%

Active ingredient Avobenzone 3%, Homosalate 10%, Octisalate 5%, Octocrylene 10%

Active ingredient Benzoyl peroxide 2.5%

🧪 Inactive Ingredients 177 words ▾

Inactive ingredients acrylates copolymer, water, cetyl alcohol, citronellol, cocamidopropyl betaine, coconut acid, colloidal sulfur, distearyl phthalic acid amide, ethylhexylglycerin, ext. violet 2 (Cl 60730), fragrance/parfum, geraniol, glycerin, hydrogenated polyisobutene, lauric acid, lauryl glucoside, limonene, linalool, myristic acid, phenoxyethanol, phytosteryl/octyldodecyl lauroyl glutamate, potassium cocoate, potassium cocoyl glycinate, potassium hydroxide, propanediol, propylene glycol, red 33 (Cl 17200), sodium chloride, sodium cocoyl isethionate, sodium isethionate, titanium dioxide (Cl 77891), tocopherol, xanthan gum

Inactive ingredients benzyl alcohol, butyloctyl salicylate, C12-15 alkyl benzoate, dimethicone crosspolymer, dimethicone/bis-isobutyl PPG-20 crosspolymer, divinyldimethicone/dimethicone/phenylsilsesquioxane crosspolymer, ethylhexylglycerin, glycerin, isododecane, linoleic acid, linolenic acid, oleic acid, palmitic acid, polymethylsilsesquioxane, polysilicone-22, silica, silica silylate, stearic acid, tocopherol, vinyl dimethicone/methicone silsesquioxane crosspolymer

Inactive ingredients allantoin, aloe barbadensis leaf juice, aminomethyl propanol, aqua/eau/water, benzyl alcohol, BHT, biosaccharide gum-1, C13-14 isoalkane, carbomer, ceramide AP, ceramide EOP, ceramide NP, chamomilla recutita (matricaria) flower extract, cholesterol, citronellol, corn starch modified, disodium EDTA, ethoxydiglycol, ethylhexylglycerin, fragrance/parfum, geraniol, glycerin, laureth-7, leuconostoc/radish root ferment filtrate, limonene, linalool, niacinamide, panthenol, PEG-7 glyceryl cocoate, phenoxyethanol, phytosphingosine, polyacrylamide, punica granatum fruit extract, sodium lauroyl lactylate, xanthan gum, yucca glauca root extract

🎯 Purpose 8 words ▾

Purpose Acne treatment

Purpose Sunscreen

Purpose Acne treatment

📄 Do Not Use 22 words ▾

Do not use on damaged or broken skin

Do not use if you have very sensitive skin are sensitive to benzoyl peroxide

📄 When Using This Product 153 words ▾

When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. rinse right away with water if it gets in eyes

When using this product keep out of eyes. Rinse with water to remove.

When using this product skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product

📄 Stop Use and Ask a Doctor If 33 words ▾

Stop use and ask a doctor if skin irritation occurs or gets worse

Stop use and ask a doctor if if rash occurs

Stop use and ask a doctor if irritation becomes severe

📄 Keep Out of Reach of Children 45 words ▾

Keep out of reach of children. If swallowed, get medical help right away.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Keep out of reach of children. If swallowed, get medical help right away.

📄 Other Information 16 words ▾

Other information protect this product from excessive heat and direct sun

Other information store 15-30°C (59-86°F)

📄 Questions or Comments 6 words ▾

Questions? 1-888-995-5656

Questions? 1-888-995-5656

Questions? 1-888-995-5656

📄 Package Label / Principal Display Panel 130 words ▾

Principal Display Panel - Kit Label RODAN+FIELDS UNBLEMISH 30-DAY REGIMEN FOR ADULT ACNE FEMALE FOUNDED DERMATOLOGIST DEVELOPED REFINING ACNE WASH SALICYLIC ACID CREAM WASH 65 ML /

2.2FL OZ. CLARIFYING TONER 60 ML / 2 FL. OZ. DUAL INTENSIVE ACNE TREATMENT BENZOYL PEROXIDE LOTION*** 2 x10 ML / 2 x

0.33FL. OZ. INVISIBLE MATTE DEFENSE BROAD SPECTRUM SPF 30 SUNSCREEN 15 ML/0.5 FL. OZ. Figure

Principal Display Panel - Refining Acne Wash Tube Label RODAN+FIELDS UNBLEMISH Refining Acne Wash Salicylic Acid Cream Wash 1 Figure

Principal Display Panel - Dual Intensive Acne Treatment Bottle Label RODAN+FIELDS UNBLEMISH Dual Intensive Acne Treatment Benzoyl Peroxide Lotion 3 Figure

Principal Display Panel - Invisible Matte Defense Tube Label RODAN+FIELDS UNBLEMISH Invisible Matte Defense Broad Spectrum SPF 30 Sunscreen Gel 4 Figure

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product Kit / multi-component package

Kit / multi-component package

This NDC identifies a kit — a package containing more than one component. Structured data (pricing, ingredients, equivalents) is often reported per component rather than for the kit NDC itself, which can make this page look thinner than the components' own pages.

What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Rodan & Fields. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Rodan & Fields is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 14222-2131-01 · Rodan 14222-2251-01 · Rodan →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.