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Esomeprazole Magnesium 20 mg Capsule, Delayed Release, 14-count — NDC 16571-0880-41 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Esomeprazole Magnesium 20 mg Capsule, Delayed Release, 14-count — NDC 16571-880-41 (Billing 16571-0880-41)

by Rising Pharma Holdings, Inc. · 1 BOTTLE in 1 CARTON / 14 CAPSULE, DELAYED RELEASE in 1 BOTTLE

This is a package of 14 capsules of Esomeprazole Magnesium 20 mg Capsule, Delayed Release from Rising Pharma Holdings, Inc., no longer marketed (first marketed Dec 2022), no longer in the FDA NDC Directory; retail pharmacies pay about $0.3460 per capsule (NADAC).

NDC 16571-0880-41
🏷️ FDA NDC (as labeled) 16571-880-41 billing pads the product segment with a zero
This package
Contains14-count Cost per ea$0.3460 NADAC Per package$4.84 / 14 capsules Pack sizes2 compare ↓
Also priced by: Part D plans $0.3386/unit — full pricing hub ↓
Product page 16571-0880-42 Also comes in: 14 capsules 16571-880-42
OTC Generic Discontinued Non-controlled ⚠ Discontinued by firm ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Oct 8, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 16571-880-41 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
16571 labeler · 880 product · 41 package
Billing quantity
14 EA per package
Barcode (UPC-A, from the NDC)
3 1657188041 6
FDA record last changed
Oct 8, 2026
⚠️
Other active recalls for Esomeprazole Magnesium (different manufacturers) — 3 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · May 13, 2025 — Failed Impurities/Degradation Specifications: Out-of-Specification test results obtained for any individual unknown degradation product during Related Compounds testing during long term stability. (Zydus Pharmaceuticals (USA) Inc) · FDA recall D-0443-2025
Class II · May 13, 2025 — Failed Impurities/Degradation Specifications: Out-of-Specification test results obtained for any individual unknown degradation product during Related Compounds testing during long term stability. (Zydus Pharmaceuticals (USA) Inc) · FDA recall D-0442-2025
Class III · Nov 14, 2024 — Labeling: Not Elsewhere Classified - Wrong NDC number (Zydus Pharmaceuticals (USA) Inc) · FDA recall D-0102-2025
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗
⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 16571-880-41
Product NDC 16571-880
11-digit billing NDC 16571088041
NCPDP billing unit EA — each (per item)
Application # ANDA216349
SPL Set ID 07ba5747-702f-47fc-9d80-5a70296b64bf
Established class (EPC) Proton Pump Inhibitor
Mechanism of action Cytochrome P450 2C19 Inhibitors; Proton Pump Inhibitors
DEA schedule Non-controlled
Marketing category ANDA
Marketing status Discontinued
FDA listing status Discontinued by firm
Marketing start 2022-12-01
Marketing end 2027-05-11
Route ORAL
Dosage form CAPSULE, DELAYED RELEASE
Substance ESOMEPRAZOLE MAGNESIUM

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GCN Seq No 047525
GCN 12867
HICL code 021607
Ingredient (HICL) Esomeprazole Magnesium
HIC1 code D
Therapeutic class — broad (HIC1) Biliary System/Gastro-Intestinal System
HIC2 code D4
Therapeutic class — intermediate (HIC2) Drugs Acting Principally On The Alimentary Tract
HIC3 code D4J
Therapeutic class — specific (HIC3) Proton-Pump Inhibitors
AHFS code 56:28.36.00
AHFS class Proton-Pump Inhibitors
FDB label name ESOMEPRAZOLE MAG DR 20 MG CAP
FDB brand name Esomeprazole Magnesium
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 047525
  • GCN: 12867
  • HICL (First Databank): 021607
  • AHFS class code: 56:28.36.00
Why two NDCs? The FDA registers this code as 16571-880-41 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 16571-0880-41. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

Label name ESOMEPRAZOLE MAG DR 20 MG CAP Ingredient Esomeprazole Magnesium
📖 What it is MedlinePlus · NLM

Prescription esomeprazole is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older. Prescription esomeprazole is used to treat damage from GERD in adults and children 1 month of age and older. Prescription esomeprazole is used to allow the esophagus to heal and prevent further damage to the esophagus in adults with GERD. Prescription esomeprazole is also used to decrease the cha...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • It lowers stomach acid. Doctors prescribe it for GERD, erosive esophagitis, preventing NSAID-related stomach ulcers, H. pylori infection (with antibiotics), and conditions like Zol...
  • Oral forms are generally taken once a day. The over-the-counter tablet is swallowed whole with water before eating in the morning for 14 days. Follow your prescriber’s directions f...
  • Not the over-the-counter versions. They can take 1 to 4 days for full effect, so they aren’t meant for immediate relief.
  • Will it relieve my heartburn right away?
📖 Read our full Esomeprazole guide →
9
Nutrient depletion considerations

Esomeprazole Magnesium may be associated with lower levels of 9 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Esomeprazole Magnesium nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.346 $4.84 / 14 capsules
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · Q2 2026 $0.3386 $4.74 / 14 capsules
NADAC price history (per ea) — tap or hover for the price & month
Dec 2023 Jan 2026 May 2026 Sep 2026 $0.369 $0.343
▼ Down 6% over the last 13 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startMarketing endStatus
16571-0880-41 You're viewing this 1 BOTTLE in 1 CARTON / 14 CAPSULE, DELAYED RELEASE in 1 BOTTLE $0.3460 / ea $4.84 2022-12-01 — Discontinued by firm
16571-0880-42 16571-880-42 Main listing 3 BOTTLE in 1 CARTON / 14 CAPSULE, DELAYED RELEASE in 1 BOTTLE $0.3460 / ea $14.53 2022-12-01 May 11, 2027 Active

This pack has the lowest per-ea cost of the 2 priced pack sizes ($0.3460 NADAC).

This pack shows little to no recent Medicaid volume — a different pack size carries most fills. See all packs ↓

Pack size FAQ

What quantity is in this package?
This is a 14-count package — 1 bottle in 1 carton / 14 capsule, delayed release in 1 bottle.
What NDC number is used to bill for this package of Esomeprazole Magnesium 20 mg Capsule, Delayed Release?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Esomeprazole Magnesium 20 mg 00378-2350-77 Mylan 90 capsules $0.145 AB Availability likely save 58%
Esomeprazole Magnesium 20 mg 16714-0979-01 NorthStar 30 capsules $0.145 AB Availability likely save 58%
Esomeprazole Magnesium 20 mg 31722-0664-10 Camber 1000 capsules $0.145 AB Availability likely save 58%
Esomeprazole magnesium 20 mg 43547-0001-03 Solco 30 capsules $0.145 AB Availability likely save 58%
Esomeprazole Magnesium 20 mg 43598-0509-10 Dr. 1000 capsules $0.145 AB Availability likely save 58%
Esomeprazole Magnesium 20 mg 60687-0934-21 American 1 capsule $0.145 AB Availability likely save 58%
Esomeprazole Magnesium 20 mg 62175-0820-32 Lannett 30 capsules $0.145 AB Availability likely save 58%
Esomeprazole magnesium 20 mg 63304-0734-10 Sun 1000 capsules $0.145 AB Availability likely save 58%
Esomeprazole magnesium 20 mg 64980-0632-03 Rising 30 capsules $0.145 AB Availability likely save 58%
esomeprazole magnesium 20 mg 68382-0441-06 Zydus 30 capsules $0.145 AB Availability likely save 58%
Esomeprazole Magnesium 20 mg 70069-0814-10 Somerset 1000 capsules $0.145 AB Availability likely save 58%
esomeprazole magnesium 20 mg 70377-0055-11 Biocon 30 capsules $0.145 AB Availability likely save 58%
Esomeprazole Magnesium 20 mg 82009-0033-10 Quallent 1000 capsules $0.145 AB Availability likely save 58%
Esomeprazole Magnesium 20 mg 68462-0390-10 Glenmark 1000 capsules $0.177 — FDA listed save 49%
Esomeprazole 20 mg 51660-0027-14 Ohm 14 capsules $0.343 — FDA listed save 1%
Good Sense Esomeprazole Magnesium 20 mg 00113-0898-01 L. 14 capsules $0.346 — Availability likely —
Esomeprazole Magnesium 20 mgthis 16571-0880-41 Rising 14 capsules $0.346 — Discontinued —
Good Neighbor Pharmacy Esomeprazole Magnesium 20 mg 46122-0641-04 Amerisource 14 capsules $0.346 — Availability likely —
Esomeprazole Magnesium 20 mg 46122-0736-03 Amerisource 14 capsules $0.346 — Availability likely —
Esomeprazole Magnesium 20 mg 69230-0320-31 Camber 14 capsules $0.346 — Availability likely —
leader esomeprazole magnesium 20 mg 70000-0727-01 Cardinal 14 capsules $0.346 — Availability likely —
Esomeprazole Magnesium 20 mg 70000-0731-01 LEADER/ 14 capsules $0.346 — Availability likely —
Foster and Thrive Acid Reducer 20 mg 70677-1099-01 Strategic 14 capsules $0.346 — Availability likely —
Esomeprazole Magnesium 20 mg 43598-0407-27 Dr. 14 capsules $0.349 — Availability likely +1%
Esomeprazole Magnesium 20 mg 63868-0425-14 CHAIN 14 capsules $0.361 — FDA listed +4%
Nexium 20 mg 00186-5020-31 AstraZeneca 30 capsules $8.777 AB Availability likely +2437%
good sense esomeprazole magnesium 20 mg 00113-0651-01 L. 14 capsules — — Discontinued —
good sense esomeprazole magnesium 20 mg 00113-2022-02 L. 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 00363-0508-05 WALGREEN 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 00363-0772-14 WALGREENS 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 00363-1699-01 Walgreen 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 00363-3298-01 Walgreens 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 00363-7223-01 Walgreen 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed Release 20 mg 00363-7810-41 WALGREENS 14 capsules — — FDA listed —
Nexium 24HR 20 mg 00573-2450-02 Haleon 2 capsules — — FDA listed —
Nexium 24HR ClearMinis 20 mg 00573-2452-02 Haleon 2 capsules — — FDA listed —
Up and Up Esomeprazole Magnesium 20 mg 11673-0753-01 Target 14 capsules — — FDA listed —
up and up esomeprazole magnesium 20 mg 11673-0898-01 Target 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 11822-0024-05 Rite 1 capsule — — FDA listed —
esomeprazole magnesium 20 mg 11822-0898-01 Rite 14 capsules — — Discontinued —
signature care esomeprazole magnesium 20 mg 21130-0088-01 Safeway 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 21130-0100-05 Better 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 21130-0257-41 BETTER 14 capsules — — FDA listed —
signature care esomeprazole magnesium 20 mg 21130-0714-01 Safeway 14 capsules — — Discontinued —
Esomeprazole magnesium 20 mg 21130-0718-41 BETTER 14 capsules — — FDA listed —
Esomeprazole 20 mg 21130-0926-14 Safeway, 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed-Release Capsules, 20 mg 25000-0075-76 MARKSANS 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed-Release 20 mg (OTC) 25000-0088-76 MARKSANS 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed Release 20 mg mini 25000-0096-76 MARKSANS 14 capsules — — FDA listed —
Esomeprazole Magnesium Delayed-Release 20 mg mini 25000-0112-76 MARKSANS 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 30142-0261-14 The 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 30142-0273-01 Kroger 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 30142-0528-14 KROGER 14 capsules — — FDA listed —
esomeprazole 20 mg 30142-0989-28 THE 14 capsules — — FDA listed —
esomeprazole 20 mg 33342-0306-07 Macleods 30 capsules — — FDA listed —
topcare esomeprazole magnesium 20 mg 36800-0627-01 Topco 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 37808-0115-14 HEB 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 37808-0364-14 H 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 37808-0719-01 H 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 41250-0727-01 Meijer 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 41250-0900-01 Meijer 14 capsules — — FDA listed —
careone esomeprazole magnesium 20 mg 41520-0727-01 American 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 42507-0774-42 HyVee 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 42507-0898-42 HyVee 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 43598-0067-42 Dr. 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 43598-0327-27 Dr. 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 43598-0812-14 Dr. 14 capsules — — Discontinued —
Esomeprazole Magnesium 20 mg 43598-0926-28 Dr. 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 45865-0163-30 Medsource 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 46122-0821-59 Amerisource 14 capsules — — FDA listed —
equate esomeprazole magnesium 20 mg 49035-0921-14 Wal-Mart 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 49035-0980-05 Wal-Mart 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 49483-0718-41 TIME 14 capsules — — FDA listed —
Nexium 24HR 20 mg 50090-1492-00 A-S 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 50090-6198-00 A-S 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 50090-6213-00 A-S 30 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 51316-0220-01 CVS 14 capsules — — FDA listed —
Esomeprazole 20 mg 51316-0715-14 CVS 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 51407-0742-10 Golden 1000 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 53041-0666-07 Guardian 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 53943-0039-14 DISCOUNT 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 53943-0527-14 Discount 14 capsules — — FDA listed —
Exchange Select Esomeprazole Magnesium 20 mg 55301-0898-01 Army 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 55319-0051-03 Family 14 capsules — — FDA listed —
dg health esomeprazole magnesium 20 mg 55910-0250-01 Dolgencorp, 14 capsules — — FDA listed —
DG Health Esomeprazole Magnesium 20 mg 55910-0593-01 Dolgencorp 14 capsules — — FDA listed —
dg health esomeprazole magnesium 20 mg 55910-0640-01 Dolgencorp 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 56062-0020-06 Publix 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 56062-0898-01 Publix 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 57483-0225-42 INNOVUS 14 capsules — — FDA listed —
Esomeprazole 20 mg 57483-0900-42 INNOVUS 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0707-05 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0809-05 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0822-05 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0846-05 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 58602-0896-62 Aurohealth 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 59651-0561-50 Aurobindo 50000 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 60000-0109-03 Ahold 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 63187-0964-30 Proficient 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 63941-0971-03 Best 14 capsules — — FDA listed —
Esomeprazole 20 mg 63941-0999-14 VALU 14 capsules — — FDA listed —
kirkland signature esomeprazole magnesium 20 mg 63981-0898-03 Costco 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 64980-0664-19 Rising 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 65862-0783-01 Aurobindo 100 capsules — AB FDA listed —
Esomeprazole magnesium 20 mg 67877-0478-05 Ascend 500 capsules — AB FDA listed —
Esomeprazole magnesium 20 mg 67877-0571-05 Ascend 500 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 68071-3419-06 NuCare 60 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 68071-3735-03 NuCare 30 capsules — AB FDA listed —
members mark esomeprazole magnesium 20 mg 68196-0898-03 Sam's 14 capsules — — FDA listed —
berkley and jensen heartburn treatment 20 mg 68391-0898-03 BJWC 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 68788-4014-09 Preferred 90 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 68788-8511-01 Preferred 100 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 69168-0472-14 Allegiant 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 69434-0012-01 Zhejiang 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 69618-0073-42 Reliable 14 capsules — — FDA listed —
Riopan 20 mg 69729-0791-14 OPMX 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 69842-0248-06 CVS 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 69842-0703-01 CVS 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 69842-0898-01 CVS 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 69844-0115-01 Graviti 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 70000-0738-01 LEADER/ 14 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 70010-0133-03 Granules 30 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 70771-1493-00 Zydus 1000 capsules — AB FDA listed —
Esomeprazole magnesium 20 mg 71205-0706-30 Proficient 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 71335-0807-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 71335-1170-01 Bryant 30 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 71335-1368-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 71335-2018-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 71335-2505-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole magnesium 20 mg 71335-9678-01 Bryant 30 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 71335-9713-01 Bryant 30 capsules — AB FDA listed —
Esomeprazole DR 20 mg 72189-0381-30 Direct_Rx 30 capsules — AB FDA listed —
Basic Care Esomeprazole Magnesium 20 mg 72288-0560-01 Amazon.com 14 capsules — — FDA listed —
basic care esomeprazole magnesium 20 mg 72288-0700-03 Amazon.com 14 capsules — — FDA listed —
basic care esomeprazole magnesium 20 mg 72288-0898-01 Amazon.com 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 72476-0500-03 Retail 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 72559-0011-06 LITTLE 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 72657-0124-42 GLENMARK 14 capsules — — FDA listed —
esomeprazole magnesium 20 mg 72657-0127-42 GLENMARK 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 72789-0352-30 PD-Rx 30 capsules — AB FDA listed —
Esomeprazole 20 mg 73581-0013-42 YYBA 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 73581-0014-42 YYBA 42 capsules — — FDA listed —
Esomeprazole magnesium 20 mg 76420-0226-30 Asclemed 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 76420-0904-00 Asclemed 1000 capsules — AB FDA listed —
esomeprazole magnesium 20 mg 79481-0411-00 Meijer, 14 capsules — — FDA listed —
equate esomeprazole magnesium 20 mg 79903-0293-42 WALMART 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 79903-0382-42 Walmart 14 capsules — — FDA listed —
Equate Esomeprazole Magnesium 20 mg 79903-0419-42 WALMART 14 capsules — — FDA listed —
Esomeprazole Magnesium DR 20 mg 80425-0111-01 Advanced 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 80425-0419-01 Advanced 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 80425-0420-01 Advanced 30 capsules — AB FDA listed —
Esomeprazole Magnesium 20 mg 83324-0200-14 CHAIN 14 capsules — — FDA listed —
24 HOUR Esomeprazole Magnesium 20 mg 85828-0718-45 Grocery 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 37808-0646-41 H-E-B 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 50090-7990-00 A-S 30 capsules — AB FDA listed —
Esomeprazole 20 mg 57896-0740-42 GERI-CARE 14 capsules — — FDA listed —
Esomeprazole Magnesium 20 mg 60760-0877-60 St. 60 capsules — AB FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2022
On the market since
Dec 2022
📍
2026
Currently FDA-listed
4 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color White
ShapeCapsule
Imprint20mg;223
Size14 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Esomeprazole inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII L06K8R7DQK
    A synthetic blue dye approved by the FDA for use in medications and foods. It serves as a colorant to make pills and liquids visually distinct and easier to identify.
  • UNII 2G86QN327L
    Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
  • UNII 73071MW2KM
    A waxy substance derived from glycerin and stearic acid that acts as a binder, emulsifier, and thickener in medicines. It helps hold solid formulations together and gives creams and lotions a smooth, stable texture.
  • UNII 230OU9XXE4
    A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
  • UNII 9XZ8H6N6OH
    A plant-based cellulose derivative used as a binder to hold tablet ingredients together, a thickener in liquids, and a coating agent to control how fast the medicine dissolves.
  • UNII R75537T0T4
    Hypromellose 2910 is a plant-derived thickening agent made from cellulose. It serves as a binder that holds tablet ingredients together, a film-coating for pills, and a viscosity controller in liquids.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII NX76LV5T8J
    A synthetic plastic polymer made from methacrylic acid and ethyl acrylate. It's used as a coating or binder to control how and where the medicine dissolves in your digestive system.
  • UNII 6OZP39ZG8H
    Polysorbate 80 is a synthetic emulsifier derived from sorbitol and oleic acid. It helps mix oil and water-based ingredients together in medications and improves how the product disperses in the body.
  • UNII 8M707QY5GH
    A sweetener and bulking agent made from crystallized sugar cane juice. It adds sweetness to the medicine and helps give the tablet or powder its solid form and texture.
  • UNII 7SEV7J4R1U
    A powder made from a naturally occurring mineral. In medicines, talc works as a glidant and anti-caking agent, helping tablets and capsules flow smoothly during manufacturing and preventing clumping.
  • UNII 8Z96QXD6UM
    Triethyl citrate is a clear liquid derived from citric acid. It acts as a plasticizer and solvent in tablet coatings and film formulations, helping the coating remain flexible and adhere properly to the medicine.

12 inactive ingredients listed in the exact product block matched to this NDC.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerRising Pharma Holdings, Inc.
Application holderGRAVITI PHARMACEUTICALS PRIVATE LTD
FDA applicationANDA216349 (ANDA)
Labeler code16571
First marketedDec 2022
Product typeHuman Otc Drug
Portfolio525 products on file

More NDCs from Rising Pharma Holdings, Inc. labeler code 16571

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📋 Description 📄 Package Label / Principal Display Panel
📋 Description ~3 min read ▾

Active ingredient (in each capsule) Purpose Esomeprazole 20 mg Acid reducer (Each delayed-release capsule corresponds to 22.250 mg esomeprazole magnesium trihydrate) Uses treats frequent heartburn (occurs 2 or more days a week) not intended for immediate relief of heartburn; this drug may take 1 to 4 days for full effect Warnings Allergy alert Do not use if you are allergic to esomeprazole Do not use if you have trouble or pain swallowing food, vomiting with blood, or bloody or black stools heartburn with lightheadedness, sweating or dizziness chest pain or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck or shoulders; or lightheadedness frequent chest pain These may be signs of a serious condition.

See your doctor. Ask a doctor before use if you have had heartburn over 3 months. This may be a sign of a more serious condition. frequent wheezing, particularly with heartburn unexplained weight loss nausea or vomiting stomach pain Ask a doctor or pharmacist before use if you are taking a prescription drug.

Acid reducers may interact with certain prescription drugs. Stop use and ask a doctor if your heartburn continues or worsens you need to take this product for more than 14 days you need to take more than 1 course of treatment every 4 months you get diarrhea you develop a rash or joint pain If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away. Directions adults 18 years of age and older this product is to be used once a day (every 24 hours), every day for 14 days may take 1 to 4 days for full effect 14-Day Course of Treatment swallow 1 capsule with a glass of water before eating in the morning take every day for 14 days do not take more than 1 capsule a day swallow whole. Do not crush or chew capsules. do not use for more than 14 days unless directed by your doctor Repeated 14-Day Courses (if needed) you may repeat a 14-day course every 4 months do not take for more than 14 days or more often than every 4 months unless directed by a doctor children under 18 years of age: ask a doctor before use.

Heartburn in children may sometimes be caused by a serious condition. Other Information read the directions and warnings before use keep the carton. It contains important information.

Store at 20° to 25°C (68° to 77°F). Esomeprazole Magnesium Delayed-Release Capsules USP, 20 mg: FD&C Blue 2, Gelatin, Hydroxypropyl Cellulose, Hypromellose, Magnesium Stearate, Methacrylic Acid and Ethyl Acrylate Copolymer Dispersion, Mono-and Di-Glycerides, Pharmaceutical Ink, Polysorbate 80, Sugar Spheres, Talc, Triethyl Citrate. Questions or comments?

Call toll-free weekdays 9 AM to 5 PM EST at 1-844-474-7464. Contact Graviti Pharmaceuticals Inc., or www.gravitipharma.com; or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch Made in India See new warning information Treats Frequent Heartburn Esomeprazole magnesium delayed-release capsules 20 mg/acid reducer May take 1 to 4 days for full effect 14 CAPSULES One 14-day course of treatment Capsules Tips for Managing Heartburn Avoid foods or drinks that are more likely to cause heartburn, such as rich, spicy, fatty and fried foods, chocolate, caffeine, alcohol and even some acidic fruits and vegetables.

Eat slowly and do not eat big meals. Do not eat late at night or just before bedtime. Do not lie flat or bend over soon after eating.

Raise the head of your bed. Wear loose-fitting clothing around your stomach. If you are overweight, lose weight.

If you smoke, quit smoking

📄 Package Label / Principal Display Panel 148 words ▾

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL Principal Display Panel - 20 mg Capsules: Container Label NDC 16571-880-41 Esomeprazole Magnesium Delayed-Release Capsules USP, 20 mg 24 HR Acid Reducer Treats Frequent Heartburn May take 1 to 4 Days for Full effect 14 Capsules One 14-day Course of Treatment Distributed by: Rising Pharma Holdings, Inc. Principal Display Panel - 20 mg Capsules: Carton Label NDC 16571-880-41 Esomeprazole Magnesium Delayed-Release Capsules USP, 20 mg 24 HR Acid Reducer Treats Frequent Heartburn May take 1 to 4 Days for Full effect 14 Capsules One 14-day Course of Treatment Distributed by: Rising Pharma Holdings, Inc.

Principal Display Panel - 20 mg Capsules: Carton Label NDC 16571-880-42 Esomeprazole Magnesium Delayed-Release Capsules USP, 20 mg 24 HR Acid Reducer Treats Frequent Heartburn May take 1 to 4 Days for Full effect 42 Capsules Three 14-day Courses of Treatment Distributed by: Rising Pharma Holdings, Inc. image image image

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicaid utilization by pack size

Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
14 capsules16571-0880-42 109 Rx · $2,428
14 capsules this page16571-0880-41 No Medicaid data
Drug total (last 4 qtrs): 109 Rx · 5,040 units · $2,428 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Esomeprazole Magnesium — the program that covers self-administered drugs. 18 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Esomeprazole Magnesium. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$26.52M
Claims incl. refills
740.1K
Beneficiaries
544.7K
Spend / beneficiary
$48.68
Spend / claim
$35.83
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) ✓ Available
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 14 capsules (16571-0880-42). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Rising Pharma Holdings, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 16571-0876-01 · Rising 16571-0881-01 · Rising →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.