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PURELL Advanced Hand Sanitizer Gentle and Free Foam alcohol .7 mL/mL Liquid, 535 mL — NDC 21749-826-53 (Billing 21749-0826-53)

by GOJO Industries, LLC · 535 mL in 1 PACKAGE

This is a package of 535 mL of PURELL Advanced Hand Sanitizer Gentle and Free Foam alcohol .7 mL/mL Liquid from GOJO Industries, LLC, marketed since Feb 2022 and currently FDA-listed. It is the main listing for this product, which comes in 3 package sizes.

NDC 21749-0826-53
🏷️ FDA NDC (as labeled) 21749-826-53 billing pads the product segment with a zero
This package
Contains535 mL Pack sizes3 compare ↓
Main listing for product 21749-826 · Also comes in: 800 ml 21749-826-80 1200 ml 21749-826-89
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 21749-826-53
Product NDC 21749-826
11-digit billing NDC 21749082653
RxCUI 616805
UNII 3K9958V90M
Application # 505G(a)(3)
SPL Set ID 70b13f86-4d1a-4221-b09d-7438163fe9b5
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2022-02-01
Route TOPICAL
Dosage form LIQUID
Substance ALCOHOL
Quick answers
  • RxCUI (RxNorm): 616805
Why two NDCs? The FDA registers this code as 21749-826-53 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 21749-0826-53. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Other antiseptics and disinfectants class.

Drug family (ATC) Other antiseptics and disinfectants, Antidotes, Nerve depressants
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It depends on the product. Hand sanitizers and wipes help reduce bacteria on your skin, and alcohol pads prepare skin before an injection. A separate injected form is used by heart...
  • Most directions say to cover all surfaces of your hands and rub until dry. Sprays and wipes follow similar steps. Check your product's label, since directions differ a bit between...
  • Children under 6 should use hand sanitizer only with adult supervision to avoid swallowing. Keep all products out of reach of children. If someone swallows it, get medical help or...
  • Stop using it and ask a doctor if you get irritation and redness, or if your condition lasts more than 72 hours. Avoid broken skin and keep it out of your eyes. If it gets in your...
📖 Read our full Alcohol guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 800 ml 1200 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
21749-0826-53 You're viewing this Main listing 535 mL in 1 PACKAGE 2022-02-01 — Active
21749-0826-80 21749-826-80 800 mL in 1 PACKAGE 2022-02-01 — Active
21749-0826-89 21749-826-89 1200 mL in 1 PACKAGE 2022-02-01 — Active

You're viewing the smallest of 3 pack sizes for this product.

Pack size FAQ

What quantity is in this package?
This package contains 535 mL — 535 ml in 1 package.
How does this package differ from NDC 21749-0826-80?
Both are PURELL Advanced Hand Sanitizer Gentle and Free Foam alcohol .7 mL/mL Liquid — the drug itself is identical. This page's package is the 535 mL one, while NDC 21749-0826-80 is the 800 ml package.
What NDC number is used to bill for this package of PURELL Advanced Hand Sanitizer Gentle and Free Foam alcohol .7 mL/mL Liquid?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
PURELL Advanced E3 Rated Instant Hand Sanitizer Foam .7 mL/mL 21749-0802-51 GOJO 550 ml — — Discontinued —
PURELL Advanced Green Certified Instant Hand Sanitizer .7 mL/mL 21749-0806-51 GOJO 550 ml — — Discontinued —
PURELL Advanced Instant Hand Sanitizer .7 mL/mL 21749-0807-17 GOJO 515 ml — — FDA listed —
PURELL Healthcare Advanced Hand Sanitizer Foam .7 mL/mL 21749-0811-45 GOJO 450 ml — — Discontinued —
PURELL Healthcare Advanced Hand Sanitizer Gentle and Free Foam .7 mL/mL 21749-0822-53 GOJO 535 ml — — FDA listed —
PURELL Advanced Hand Sanitizer Gentle and Free Foam .7 mL/mLthis 21749-0826-53 GOJO 535 ml — — FDA listed —
PURELL Advanced Hand Sanitizer Fragrance Free Foam .7 mL/mL 21749-0827-17 GOJO 515 ml — — FDA listed —
PURELL Advanced Hand Sanitizer Moisturizing 2in1 Foam 70 mL/100mL 21749-0851-10 GOJO 295 ml — — FDA listed —
PURELL Healthcare Advanced Hand Sanitizer ULTRA NOURISHING Foam .7 mL/mL 21749-0854-53 GOJO 535 ml — — FDA listed —
PURELL Advanced Hand Sanitizer ULTRA NOURISHING Foam 70 mL/100mL 21749-0856-17 GOJO 515 ml — — FDA listed —
PURELL Advanced Hand Sanitizer Naturals Foam 70 mL/100mL 21749-0875-10 GOJO 295 ml — — FDA listed —
Symmetry Foaming Hand Sanitizer Fragrance Free 70 mL/100mL 30805-0020-04 Buckeye 1200 ml — — FDA listed —
Symmetry Foaming Hand Sanitizer 70 mL/100mL 30805-0021-09 Buckeye 1000 ml — — FDA listed —
Altra Foaming Hand Sanitizer Fragrance Free with Aloe and Vitamin E 70 mL/100mL 30805-0023-07 Buckeye 550 ml — — FDA listed —
I-70 Foaming .7 mL/mL 43097-0968-12 People's 1000 ml — — FDA listed —
ESC Protecting Foam Hand Sanitizer 76.9 mL/100mL 47593-0667-41 Ecolab 750 ml — — FDA listed —
Ecolab Retail Foaming Alcohol Hand Sanitizer 70 mL/100mL 47593-0685-56 Ecolab 1200 ml — — FDA listed —
Kay Alcohol Foam Hand Sanitizer 70 mL/100mL 47593-0686-56 Ecolab 1200 ml — — FDA listed —
Tork Hand Sanitizing Alcohol Foam 70 mL/100mL 49351-0301-01 Essity 1000 ml — — FDA listed —
Foaming Hand Sanitizer 70 mL/100mL 50021-0020-01 Empack 550 ml — — FDA listed —
MG FoamSan 70 .7 L/L 50241-0223-02 Morgan 3.785 l — — FDA listed —
EnMotion Foam Hand Sanitizer 70 mL/100mL 54622-0120-01 Georgia-Pacific 1000 ml — — FDA listed —
enMotion Foam High Frequency Use .7 mL/mL 54622-0121-01 Georgia-Pacific 2 bottles — — FDA listed —
Pacific Blue Ultra Foaming Fragrance Free 70 mg/mL 54622-0122-01 Georgia-Pacific 1000 ml — — FDA listed —
Pacific Blue Select Foam Hand Sanitizer, Fragrance Free, Dye Free 70 mL/100mL 54622-0311-01 Georgia-Pacific 24 bottles — — FDA listed —
enMotion Foam High Frequency Use 70 mL/100mL 54622-0486-01 Georgia-Pacific 1000 ml — — FDA listed —
Kleenex Ultra Moisturizing Hand Sanitizer 70 mL/100mL 55118-0530-10 Kimberly-Clark 1000 ml — — Discontinued —
Kleenex Reveal Moisturizing Foam Hand Sanitizer 70 mL/100mL 55118-0531-10 Kimberly-Clark 6 bottles — — Discontinued —
Lynx san a foam .7 mL/mL 62257-0007-10 ABC 1000 ml — — FDA listed —
Fast .7 mL/mL 62257-0658-08 ABC 1000 ml — — Discontinued —
Dermacen Foaming Instant Hand Sanitizer With Aloe 70 mL/100mL 62654-0149-13 Central 1000 ml — — FDA listed —
Saniclean 70 g/100mL 63900-0150-02 Simoniz 1000 ml — — FDA listed —
Foaming Instant Hand Sanitizer with Aloe 70 g/100g 68599-5205-01 MCKESSON 251 g — — FDA listed —
Hand Sanitizer 70 mL/100mL 69790-0456-44 Uline 532 ml — — FDA listed —
EXTENDED CARE Foaming Hand Sanitizer .7 mL/mL 71875-0800-40 TRIPLE 1200 ml — — FDA listed —
Hand Sanitizer 70 mL/100mL 71897-0465-86 Veritiv 1000 ml — — FDA listed —
Clean Revolution Foaming Hand Sanitizer Refill Supply Container - Gentle and Aloe Enriched - ELIMINATES 99.9% Germs - 70% Ethanol - Ready To Use 70 mL/100mL 74810-0725-00 Replenish 3785 ml — — FDA listed —
Recens Foam .7 mL/mL 75990-0968-07 Certus 700 ml — — Discontinued —
Hand Sanitizer 70 mL/100mL 76370-0003-01 Tazza 10000 ml — — Discontinued —
Hand Sanitizer 70 mL/100mL 76370-0005-02 Tazza 3785 ml — — Discontinued —
Tazza 70% Alcohol-Based Hand Sanitizing Foam 70 L/100L 76370-0033-00 Tazza 3.785 l — — FDA listed —
Hand Sanitizer Foam 70 mL/100mL 77955-0002-02 Custom 1000 ml — — FDA listed —
Ops 70 Percent Alcohol Foaming Skin Sanitizer 70 mL/100mL 79016-0101-12 Archer 1000 ml — — FDA listed —
Black Ops 70 Percent Alcohol Foaming Skin Sanitizer 70 mL/100mL 79016-0102-12 Archer 1000 ml — — FDA listed —
KleenLine Essentials Foaming Hand Sanitizer .7 mL/mL 79258-0802-29 Brady 1000 ml — — FDA listed —
MyHealth Advanced Hand Sanitizer 70 mL/100mL 80661-0002-01 Aeroflex 150 ml — — FDA listed —
Novo Foaming Instant Hand Sanitizer .7 mL/mL 81551-0802-04 Noble 3785 ml — — FDA listed —
Foaming Hand Alcohol Foam 70 mL/100mL 83019-0102-11 Draco 1000 ml — — FDA listed —
PURELL Advanced Hand Sanitizer Fragrance Free .7 mL/mL 21749-0532-01 GOJO 1.2 ml — — FDA listed —
PURELL Advanced Instant Hand Sanitizer .7 mL/mL 21749-0700-00 GOJO 1.2 ml — — Discontinued —
PURELL Waterless Surgical Scrub .7 mL/mL 21749-0992-02 GOJO 59 ml — — FDA listed —
Sani-Spritz .7 mL/mL 62257-0738-15 ABC 946 ml — — FDA listed —
PURELL Advanced Hand Sanitizer Biobased Content .7 mL/mL 21749-0022-02 GOJO 60 ml — — FDA listed —
Hand San .7 mL/mL 59503-2605-01 Rochester 472 ml — — Discontinued —
Germ Attack Hand Sanitizer .7 mL/mL 66902-0482-02 Natural 59 ml — — FDA listed —
PURELL Advanced Hand Sanitizer Green Certified Foam .7 mL/mL 21749-0808-51 GOJO 550 ml — — FDA listed —
PURELL Advanced Hand Sanitizer Gel .7 mL/mL 21749-0709-45 GOJO 450 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2022
On the market since
Feb 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII A7E6112E4N
    A form of vitamin E used as an antioxidant in medicines. It prevents oils and fats in the product from breaking down, helping maintain stability and shelf life.
  • UNII 00YIU5438U
    Caprylyl glycol is a clear liquid derived from coconut oil. In medicines, it acts as a humectant to retain moisture, a preservative booster to prevent microbial growth, and a solvent to help dissolve or mix other ingredients.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII ND2M416302
    Isopropyl alcohol is a clear liquid solvent derived from petroleum. In medicines, it dissolves active ingredients and other components, helps the product flow smoothly, and aids in sterilization during manufacturing.
  • UNII 0RE8K4LNJS
    Isopropyl myristate is an oily liquid made from coconut or palm oil. It's used in medicines as an emollient and penetration enhancer to help the medicine absorb through skin or improve spreadability in topical products.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

6 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesWater (Aqua), Isopropyl Alcohol, PEG-12 Dimethicone, Caprylyl Glycol, Glycerin, Isopropyl Myristate, Tocopheryl Acetate

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerGOJO Industries, LLC
FDA application505G(a)(3) (OTC MONOGRAPH DRUG)
Labeler code21749
First marketedFeb 2022
Product typeHuman Otc Drug
Portfolio15 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 17 words ▾

Uses Hand sanitizer to help reduce bacteria on the skin that cause disease Recommended for repeated use

⏱️ Dosage and Administration 31 words ▾

Directions Place enough product in your palm to thoroughly cover your hands Run hands together briskly until dry Children under 6 years of age should be supervised when using this product.

⚠️ Warnings 65 words ▾

Warnings Flammable. Keep away from fire or flame. For external use only When using this product do not use in or near the eyes. In case of contact, rinse eyes thoroughly with water. Stop use and ask a doctor if irritation or rash appears and lasts Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 6 words ▾

Active ingredient Ethyl alcohol 70% v/v

🧪 Inactive Ingredients 15 words ▾

Inactive ingredients Water (Aqua), Isopropyl Alcohol, PEG-12 Dimethicone, Caprylyl Glycol, Glycerin, Isopropyl Myristate, Tocopheryl Acetate

🎯 Purpose 2 words ▾

Purpose Antimicrobial

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for PURELL Advanced Hand Sanitizer Gentle and Free Foam (this brand).

Top reported reactions

Toxicity To Various Agents6,004
Completed Suicide5,432
Drug Abuse5,289
Overdose1,887
Death1,594
Intentional Overdose1,541
Cardio-respiratory Arrest1,345

Reporter sex

26,729 reports

Serious outcomes

Death15,128
Life-threatening1,403
Disabling212
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 2,158 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by GOJO Industries, LLC. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 800 ml (21749-0826-80), 1200 ml (21749-0826-89). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
GOJO Industries, LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 21749-0822-53 · GOJO 21749-0827-17 · GOJO →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.