NDC 48102-0057-11 — Erythromycin 5 mg/g Ointment, 50 tubes

🆔 Identity & classification

FDA NDC (as labeled) 48102-057-11

Product NDC 48102-057

11-digit billing NDC 48102005711

NCPDP billing unit GM — per gram (weight)

RxCUI 310149

UNII 63937KV33D

UPC 0348102057110

SPL Set ID be59bb85-8ef4-4f9e-85e5-c05662ecd1ee

Established class (EPC) Macrolide; Macrolide Antimicrobial

Physiologic effect Decreased Sebaceous Gland Activity

Chemical class Macrolides

DEA schedule Non-controlled

Marketing category UNAPPROVED DRUG FOR USE IN DRUG SHORTAGE

Marketing status On market

FDA listing status Listed (active directory)

Marketing start 2023-09-27

Route OPHTHALMIC

Dosage form OINTMENT

Substance ERYTHROMYCIN

GCN Seq No 007948

GCN 33540

HICL code 004022

Ingredient (HICL) Erythromycin Base

HIC1 code Q

Therapeutic class — broad (HIC1) Ear/Eye/Nose/Rectum/Topical/Vagina/Other

HIC2 code Q6

Therapeutic class — intermediate (HIC2) Ophthalmic Preparations

HIC3 code Q6W

Therapeutic class — specific (HIC3) Ophthalmic Antibiotics

AHFS code 08:12.12.04

AHFS class Erythromycin Antibiotics

FDB label name ERYTHROMYCIN 0.5% EYE OINTMENT

FDB brand name Erythromycin

Legend status F — Federal legend — prescription drug or device

Why two NDCs? The FDA registers this code as 48102-057-11 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 48102-0057-11. Same drug, same package — only the format differs.

Where does this data come from?

Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Macrolide class.

Pharmacologic class Macrolide, Macrolide Antimicrobial

Drug family (ATC) Antiinfectives for treatment of acne, Macrolides, Antibiotics

Where does this data come from?

Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerFera Pharmaceuticals, LLC

Labeler code48102

First marketedSep 2023

Product typeHuman Prescription Drug

Portfolio3 products on file

🔎 All NDCs from Fera Pharmaceuticals, LLC

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).

Where does this data come from?

Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name ERYTHROMYCIN 0.5% EYE OINTMENT Ingredient Erythromycin Base

📖 What it is MedlinePlus · NLM

Erythromycin ophthalmic is used to treat bacterial infections of the eye and prevent bacterial infections of the eye in newborn babies. Erythromycin is in a class of medications called macrolide antibiotics. It works by killing bacteria that cause infections.

Read the full MedlinePlus article ↗

📗 Our plain-language guide HelloPharmacist

Erythromycin treats a pretty wide range of bacterial infections. That includes respiratory infections like bronchitis and pneumonia, skin infections, whooping cough, Legionnaires'...
What kinds of infections does erythromycin treat?
It depends on the form you have. If you're taking ERY-TAB delayed-release tablets, they work best on an empty stomach — ideally about 2 hours before a meal, though taking them with...
Can I take this on an empty stomach, or do I need food?

📖 Read our full Erythromycin guide →

Patient education

📘 MedlinePlus patient leaflet ↗

Supplement & herbal interactions

Some supplements/herbs that may interact with Erythromycin — tap one for details:

Activated CharcoalMajor Coffee CharcoalModerate European MandrakeModerate GlucomannanModerate Guar GumModerate Gum ArabicModerate Slippery ElmModerate TragacanthModerate

🌿 Every supplement checked against Erythromycin (204 interactions) — ranked by severity →

7

Nutrient depletion considerations

Erythromycin may be associated with lower levels of 7 nutrients — worth a chat with your pharmacist, not a cause for alarm.

BIOTIN Insignificant Depletion FOLIC ACID Insignificant Depletion RIBOFLAVIN Insignificant Depletion THIAMINE Insignificant Depletion VITAMIN B12 Insignificant Depletion +2 more

🧪 Full Erythromycin nutrient depletion report →

An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.

Where does this data come from?

Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

UNII T5L8T28FGP
Mineral oil is a clear, odorless liquid derived from crude oil. It acts as a lubricant and emollient in medications, helping pills slide smoothly during manufacturing and aiding moisture retention in topical products.
UNII 4T6H12BN9U
Petrolatum is a purified mineral oil-based jelly derived from petroleum. In medicines, it acts as an emollient, lubricant, and moisture barrier to soften skin, reduce friction, and help prevent water loss from formulations.

2 inactive ingredients listed in the exact product block matched to this NDC.

Where does this data come from?

Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?

No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.

Why might an inactive ingredient be missing?

Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.

Can inactive ingredients matter?

Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price system	Per g	Per package
Retail pharmacies payNADAC · weekly	Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo	No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · Q2 2026	$3.24	$162.05 / 50 g

Where does this data come from?

NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

Product	Labeler	Pack	NADAC/unit	TE	Status	Price vs. this
Erythromycin 5 mg/g 24208-0910-19	Bausch	50 tubes	$6.716	AT	Availability likely	—
Erythromycin 5 mg/g 70244-0031-01	Sentiss	50 tubes	$6.716	AT	Availability likely	—
Erythromycin 5 mg/g 72485-0670-31	ARMAS	50 tubes	$6.716	AT	Availability likely	—
Erythromycin 5 mg/gthis 48102-0057-11	Fera	50 tubes	—	—	FDA listed	—
Erythromycin 5 mg/g 50090-1484-00	A-S	1 tube	—	AT	FDA listed	—
erythromycin 5 mg/g 50090-1958-00	A-S	1 tube	—	—	FDA listed	—
Erythromycin 5 mg/g 55154-7850-00	Cardinal	10 tubes	—	AT	FDA listed	—
Erythromycin 5 mg/g 60760-0670-35	ST.	1 tube	—	AT	FDA listed	—
Erythromycin 5 mg/g 61919-0090-35	Direct	3.5 g	—	AT	FDA listed	—
Erythromycin 5 mg/g 63187-0267-35	Proficient	1 tube	—	AT	FDA listed	—
Erythromycin 5 mg/g 63187-0608-35	Proficient	1 tube	—	AT	FDA listed	—
Erythromycin 5 mg/g 66267-0975-35	NuCare	3.5 g	—	AT	FDA listed	—
Erythromycin 5 mg/g 67296-2128-03	Redpharm	1 tube	—	AT	FDA listed	—
Erythromycin 5 mg/g 68071-3992-02	NuCare	1 tube	—	AT	FDA listed	—
Erythromycin 5 mg/g 68071-4228-03	NuCare	3.5 g	—	AT	FDA listed	—
erythromycin 5 mg/g 68071-4803-03	NuCare	3.5 g	—	—	FDA listed	—
Erythromycin 5 mg/g 68788-9328-03	Preferred	1 tube	—	AT	FDA listed	—
Erythromycin 5 mg/g 70518-0465-00	REMEDYREPACK	1 tube	—	AT	FDA listed	—
Erythromycin 5 mg/g 76420-0196-03	Asclemed	1 tube	—	AT	FDA listed	—
Erythromycin 5 mg/g 76420-0212-30	Asclemed	1 tube	—	AT	FDA listed	—
erythromycin 5 mg/g 76420-0612-03	Asclemed	1 tube	—	—	FDA listed	—
Erythromycin 5 mg/g 85766-0248-55	Sportpharm	1 tube	—	AT	FDA listed	—

About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.

Where does this data come from?

Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️

2023

On the market since

Sep 2023

📍

2026

Currently FDA-listed

3 years listed

🔓

·

Generic versions listed

see equivalents

✅Generic appears available

FDA-approved generic versions are listed, and recent pricing/market data suggests they may be available — see Therapeutic equivalents.

Where does this data come from?

Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📊 Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Erythromycin — the program that covers self-administered drugs. 12 manufacturers.

⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Erythromycin. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.

Period

Total Part D spend

$6.84M

Claims incl. refills

399.1K

Beneficiaries

329.3K

Spend / beneficiary

$20.78

Spend / claim

$17.15

Trend by period

💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

📦 Packaging — all sizes for this product

Package NDC	Description	Marketing start	Status
48102-0057-11 You're viewing this	50 TUBE in 1 CARTON (48102-057-11) / 1 g in 1 TUBE	2023-09-27	Active

🧭 About this NDC listing & data coverage

Finished prescription product Marketed without an FDA application

Listed without an FDA application

This product's marketing category indicates it is marketed without an approved FDA application (no NDA, ANDA, or BLA on file). Having an NDC does not by itself establish FDA approval — the NDC Directory is a listing system, not an approval decision. Approval-linked data such as Orange Book therapeutic-equivalence ratings therefore does not apply.

What data is (and isn’t) available for this NDC — tap to expand

NDC identity (package / product / labeler codes)	✓ Available
Labeler	✓ Available
Product & package description	✓ Available
Marketing category & status	✓ Available
Active ingredient / dosage form / route	✓ Available
FDA label (SPL via DailyMed)	✓ Available
Package photos	✓ Available
Inactive ingredients (structured)	✓ Available
NADAC pharmacy acquisition price (CMS)	— Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data	— Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk	— Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD)	— Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.

“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?

An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Drug For Use In Drug Shortage". Products approved under an application carry an NDA, ANDA, or BLA number.

Why is there no price listed?

The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.

Is the NDC printed on the package the same as the 11-digit billing NDC?

Yes, they identify this exact package in different formats. The FDA registers it as 48102-057-11, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 48102-0057-11, written without dashes as 48102005711. The Identity section at the top of this page lists every form of this code.

What do the three segments of this NDC mean?

In 48102-0057-11, the first segment (48102) is the labeler code FDA assigned to Fera Pharmaceuticals, LLC; the middle segment (0057) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (11) identifies this exact package size and type. Together they name one specific package of one specific product.

Is this package still being marketed?

Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Fera Pharmaceuticals, LLC. Listing status can change — the directory data on this page refreshes weekly.

Who lists this product with the FDA?

Fera Pharmaceuticals, LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.

Do I need a prescription for this product?

This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.

This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.

Where does this data come from?

Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.

📄 FDA label

📄 FDA label 9 words ▾

No readable label sections were found for this product.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

🔗 Related NDC lookups

🧪 All Erythromycin NDCsSame ingredient 🏭 All Fera labeler NDCsLabeler code 48102 📚 All Macrolide Antimicrobial NDCsDrug class 📖 Read the Erythromycin drug informationUses, warnings & side effects

💊 Related drugs in this class

Other drugs that share this product’s specific therapeutic class — Ophthalmic Antibiotics.

Gatifloxacin 00023-3615-01 Polymyxin B Sulf/Trimethoprim 00023-7824-10 Tobramycin 00065-0643-05 Ciprofloxacin Hcl 00065-0656-05 Moxifloxacin Hcl 00078-0939-26 Bacitracin/Polymyxin B Sulfate 00574-4021-35 Bacitracin 00574-4022-35 Neomycin/Bacitracin/Polymyxinb 00574-4250-35 Ofloxacin 00904-7434-05 Levofloxacin 16571-0150-50 Gentamicin Sulfate 17478-0283-10 Azithromycin 17478-0307-03 Besifloxacin Hcl 24208-0446-02 Neomycin/Polymyxn B/Gramicidin 24208-0790-62

Where does this data come from?

Other drugs sharing this product’s First Databank therapeutic class (HIC3). Each links to that NDC’s page in our directory.