Vichy Laboratories LiftActiv Peptide-C SPF 30 Phyto Peptides Vitamin C Avobenzone, Homosalate, Octisalate and Octocrylene 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL Lotion, 1 mL — NDC 49967-0684-02 package photo

Vichy Laboratories LiftActiv Peptide-C SPF 30 Phyto Peptides Vitamin C Avobenzone, Homosalate, Octisalate and Octocrylene 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL Lotion, 1 mL

by L'Oreal USA Products Inc · 1 mL in 1 PACKET (49967-684-02)
NDC 49967-0684-02
🏷️ FDA NDC (as labeled) 49967-684-02 billing pads the product segment with a zero
This package
Contains1 mL Pack sizes2 compare ↓
Also comes in: 50 mL 49967-0684-03
OTC Discontinued Non-controlled ⚠ Discontinued by firm
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
⚠️
Excluded from the active FDA NDC Directory. The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory. Search the FDA NDC Directory ↗

🆔 Identity & classification

FDA NDC (as labeled) 49967-684-02
Product NDC 49967-684
11-digit billing NDC 49967068402
UNII G63QQF2NOX, V06SV4M95S, 4X49Y0596W, 5A68WGF6WM
Application # M020
SPL Set ID 40fd5146-f4f0-4c2d-a786-d18f8ade1bef
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status Discontinued
FDA listing status Discontinued by firm
Marketing start 2019-12-27
Route TOPICAL
Dosage form LOTION
Substance AVOBENZONE; HOMOSALATE; OCTISALATE; OCTOCRYLENE
Why two NDCs? The FDA registers this code as 49967-684-02 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 49967-0684-02. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerL'Oreal USA Products Inc
FDA applicationM020 (OTC MONOGRAPH DRUG)
Labeler code49967
First marketedDec 2019
Product typeHuman Otc Drug
Portfolio197 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is a topical lotion marketed as a cosmetic sunscreen under FDA's over-the-counter monograph rules. It contains four UV filter ingredients (avobenzone, homosalate, octisalate, and octocrylene) that are typically used together to absorb and scatter ultraviolet radiation from the sun. The product is formulated to be applied to the skin to help reduce sun exposure. It also includes peptides and vitamin C as additional ingredients commonly found in skincare products.

Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII F01RIY4371
    A synthetic polymer made from acrylic compounds and taurate, this substance acts as a thickener and stabilizer. It helps give liquid medicines a smooth texture and keeps ingredients from separating.
  • UNII 2V52R0NHXW
    Ascorbyl glucoside is a stable form of vitamin C derived from ascorbic acid and glucose. It functions as an antioxidant in medicines to protect other ingredients from breaking down when exposed to air or light.
  • UNII JV039JZZ3A
    Betadex is a modified sugar molecule derived from starch. It acts as a solubilizer and stabilizer in medicines, helping dissolve poorly soluble drugs and keep them stable during storage.
  • UNII 00YIU5438U
    Caprylyl glycol is a clear liquid derived from coconut oil. In medicines, it acts as a humectant to retain moisture, a preservative booster to prevent microbial growth, and a solvent to help dissolve or mix other ingredients.
  • UNII 609A3V1SUA
    A silky liquid derived from caprylic acid that acts as an emollient and solvent in formulations. It helps dissolve active ingredients and improves the spreadability and feel of lotions, creams, and topical products.
  • UNII 92RU3N3Y1O
    Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
  • UNII 9E4CO0W6C5
    A silicone-based polymer that forms soft, spongy particles. Used as a texture modifier and suspending agent to improve how the product feels and flows, and to help keep ingredients evenly distributed throughout the formulation.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 230OU9XXE4
    A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
  • UNII 0WT12SX38S
    Glycolic acid is an alpha-hydroxy acid derived from sugar cane that helps dissolve and remove dead skin cells. In topical medicines, it works as an exfoliant and pH adjuster to improve skin penetration and product effectiveness.
  • UNII 12133JR80S
    Guanosine is a natural nucleoside compound derived from nucleic acids. In medicines, it may serve as a buffer or pH regulator to help stabilize the formulation and maintain proper acidity levels.
  • UNII YSE9PPT4TH
    Hyaluronate sodium is a natural carbohydrate that holds moisture. It's used in medicines as a lubricant, thickener, and moisture-retaining agent to improve texture and delivery of the active ingredient.
  • UNII 0I3V7S25AW
    Myristic acid is a natural fatty acid commonly derived from palm or coconut oil. In medicines, it acts as a lubricant and binding agent, helping tablets hold together and slide smoothly through manufacturing equipment.
  • UNII 2V16EO95H1
    Palmitic acid is a saturated fatty acid derived from plant and animal sources. It serves as an emulsifier and lubricant in medicines, helping ingredients mix smoothly and preventing sticking during manufacturing.
  • UNII W4X7H8GYFM
    Polyethylene glycol (PEA) is a synthetic polymer derived from petroleum. It functions as a solvent, lubricant, and binder in medications to improve texture, reduce sticking, and help bind ingredients together.
  • UNII YD01N1999R
    A waxy substance made from polyethylene glycol and stearic acid. It helps mix oil and water-based ingredients together and serves as an emulsifier and solubilizer in liquid and semi-solid medicines.
  • UNII 255PIF62MS
    A synthetic antioxidant compound used to prevent oils and fats in medications from breaking down or becoming rancid during storage. It helps maintain the medicine's stability and shelf life.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII G37UFG162O
    A synthetic compound that acts as a preservative and antioxidant in medications. It helps prevent bacterial and fungal growth while protecting the medicine from degradation caused by oxygen exposure.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
  • UNII 55X04QC32I
    A strong alkaline chemical used to adjust and maintain the pH balance of liquid medicines. It helps keep the medicine stable and ensures it stays effective during storage.
  • UNII 4OH5W9UM87
    A synthetic emulsifier and surfactant derived from stearic acid. It helps oils and water mix together in liquid medicines and creams, and improves how the product spreads and feels on the skin.
  • UNII 4ELV7Z65AP
    Stearic acid is a fatty acid derived from plant or animal sources. It acts as a binder and lubricant in tablets and capsules, helping them hold together and flow smoothly during manufacturing.
  • UNII R0ZB2556P8
    Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
  • UNII YA22H34H9Q
    A chelating agent derived from sodium and organic compounds. It binds to metal ions in the formulation to improve stability and prevent unwanted chemical reactions that could degrade the medicine.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII TTV12P4NEE
    Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.

27 inactive ingredients listed in the exact product block matched to this NDC.

The official label also stateswater, glycerin, dimethicone, silica, PEG-100 stearate, glyceryl stearate, glycolic acid, stearic acid, dicaprylyl carbonate, steareth-100, dimethicone/vinyl dimethicone crosspolymer, sodium hydroxide, sodium hyaluronate, myristic acid, cyclodextrin, palmitic acid, phenoxyethanol,  henylethyl resorcinol, guanosine, ammonium polyacryloyldimethyl taurate, ascorbyl glucoside, tocopherol, caprylyl glycol, trisodium ethylenediamine disuccinate, xanthan gum, pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, pisum sativum (pea) extract, fragrance

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMedingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 50 mL
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
LOreal Paris Revitalift Triple Power Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0082-01 L'Oreal 1 bottle FDA listed
Kiehls Since 1851 Ultra Facial Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0099-01 LOreal 50 ml FDA listed
Kiehls Since 1851 Super Multi Corrective Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0410-01 LOreal 50 ml FDA listed
LOreal Paris Skin Expert Revitalift Bright Reveal Brightening Day Moisturizer Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0504-01 L'Oreal 1 bottle FDA listed
La Roche Posay Laboratoire Dermatologique Pigmentclar Daily Dark Spot Correcting Moisturizer Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0664-01 L'Oreal 1 tube FDA listed
Vichy Laboratories LiftActiv Peptide-C SPF 30 Phyto Peptides Vitamin C 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mLthis 49967-0684-02 L'Oreal 1 ml Discontinued
Lancome Paris Renergie Lift MultiAction Ultra Firming and Dark Spot Correcting Moisturizer Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0768-01 L'Oreal 1 bottle Discontinued
Vichy Laboratoires Aqualia Thermal UV Defense Moisturizer Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0869-01 L'Oreal 1 bottle FDA listed
Kiehls Since 1851 Ultra Facial Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0941-01 LOreal 50 ml FDA listed
Vichy Laboratories LiftActiv Peptide-C SPF 30 Sunscreen Phyto Peptides Vitamin C 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 69625-0685-03 Cosmetique 1 tube FDA listed
Vichy Laboratoires Aqualia Thermal UV Defense Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 69625-0868-01 Cosmetique 1 bottle FDA listed
NYX Professional Makeup Bare with Me Daily Moisturizing Primer with Cannabis Sativa Seed Oil SPF 30 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0217-01 L'Oreal 1 bottle FDA listed
La Roche Posay Laboratoire Dermatologique Toleriane Double Repair Moisturizer UV Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0584-02 LOreal 2 ml FDA listed
Kiehls Ultra Facial Moisturizer Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 49967-0894-01 L'Oreal 125 ml FDA listed
La Roche Posay Laboratoire Dermatologique Toleriane Double Repair UV Broad Spectrum SPF 30 Sunscreen 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL 69625-0583-02 Cosmetique 2 ml FDA listed
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2019
On the market since
Dec 2019
📍
2026
Currently FDA-listed
7 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
49967-0684-02 You're viewing this 1 mL in 1 PACKET (49967-684-02) 2019-12-27 Discontinued by firm
49967-0684-03 1 TUBE in 1 CARTON (49967-684-03) / 50 mL in 1 TUBE 2019-12-27 Active

Pack size FAQ

What quantity is in NDC 49967-0684-02?
NDC 49967-0684-02 contains 1 mL — 1 ml in 1 packet.
What NDC number is used to bill for this package of Vichy Laboratories LiftActiv Peptide-C SPF 30 Phyto Peptides Vitamin C Avobenzone, Homosalate, Octisalate and Octocrylene 30 mg/mL; 50 mg/mL; 50 mg/mL; 70 mg/mL Lotion?
Bill NDC 49967-0684-02 — the 11-digit billing format is 49967068402. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 49967-684-02, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 49967-0684-02, written without dashes as 49967068402. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 49967-0684-02, the first segment (49967) is the labeler code FDA assigned to L'Oreal USA Products Inc; the middle segment (0684) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (02) identifies this exact package size and type. Together they name one specific package of one specific product.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 1 tube (49967-0684-03). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
L'Oreal USA Products Inc is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage 30 words

Uses help prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun

⏱️ Dosage and Administration 94 words

Directions For sunscreen use: apply liberally 15 minutes before sun exposure reapply at least every 2 hours use a water resistant sunscreen if swimming or sweating Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a suncreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m.-2 p.m. wear long-sleeved shirts, pants, hats, and sunglasses children under 6 months of age: Ask a doctor

⚠️ Warnings 5 words

Warnings For external use only

📦 Storage and Handling 14 words

Other information protect the product in this container from excessive heat and direct sun

🧪 Active Ingredient 10 words

Active ingredients Avobenzone 3% Homosalate 5% Octisalate 5% Octocrylene 7%

🧪 Inactive Ingredients 54 words

Inactive ingredients water, glycerin, dimethicone, silica, PEG-100 stearate, glyceryl stearate, glycolic acid, stearic acid, dicaprylyl carbonate, steareth-100, dimethicone/vinyl dimethicone crosspolymer, sodium hydroxide, sodium hyaluronate, myristic acid, cyclodextrin, palmitic acid, phenoxyethanol, henylethyl resorcinol, guanosine, ammonium polyacryloyldimethyl taurate, ascorbyl glucoside, tocopherol, caprylyl glycol, trisodium ethylenediamine disuccinate, xanthan gum, pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, pisum sativum (pea) extract, fragrance

🎯 Purpose 2 words

Purpose Sunscreen

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.