NDC 51927-3408-00 — FAMOTIDINE 1 kg/kg Powder, 1 kg

🆔 Identity & classification

FDA NDC (as labeled) 51927-3408-0

Product NDC 51927-3408

11-digit billing NDC 51927340800

SPL Set ID 483d28e1-0631-9932-e063-6294a90aa9cc

DEA schedule Non-controlled

Marketing category BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING

Marketing status On market

FDA listing status Listed (active directory)

Marketing start 2002-07-19

Dosage form POWDER

Substance FAMOTIDINE

GPI-14 96524239442900

GPI class Famotidine

GCN Seq No 053502

GCN 21001

HICL code 004521

Ingredient (HICL) Famotidine

HIC1 code U

Therapeutic class — broad (HIC1) Miscell. Drugs/ Pharmaceutical Adjuvants

HIC2 code U6

Therapeutic class — intermediate (HIC2) Pharmaceutical Adjuvants

HIC3 code U6W

Therapeutic class — specific (HIC3) Bulk Chemicals

AHFS code 56:28.12.00

AHFS class Histamine H2-Antagonists

FDB label name FAMOTIDINE POWDER

FDB brand name Famotidine

Legend status F — Federal legend — prescription drug or device

Why two NDCs? The FDA registers this code as 51927-3408-0 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 51927-3408-00. Same drug, same package — only the format differs.

Where does this data come from?

Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerProfessional Compounding Centers of America dba PCCA

Labeler code51927

First marketedJul 2002

Product typeBulk Ingredient

Portfolio256 products on file

🔎 All NDCs from Professional Compounding Centers of Amer...

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).

Where does this data come from?

Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name FAMOTIDINE POWDER Ingredient Famotidine

📗 Our plain-language guide HelloPharmacist

Great question. Antacids (like Tums) neutralize acid that's already in your stomach — they work fast but don't last long. Famotidine is different: it actually blocks a signal in yo...
What exactly does famotidine do — and how is it different from antacids?
The over-the-counter tablets are meant to relieve heartburn when it happens, or to prevent it if you take them 10 to 60 minutes before a meal that usually causes trouble. You shoul...
Can I take the OTC version whenever I have heartburn, or is there a limit?

📖 Read our full Famotidine guide →

Patient education

📘 MedlinePlus patient leaflet ↗

Supplement & herbal interactions

Some supplements/herbs that may interact with Famotidine — tap one for details:

Activated CharcoalMajor Coffee CharcoalModerate European MandrakeModerate GlucomannanModerate Guar GumModerate Gum ArabicModerate Slippery ElmModerate TragacanthModerate

🌿 Every supplement checked against Famotidine (41 interactions) — ranked by severity →

6

Nutrient depletion considerations

Famotidine may be associated with lower levels of 6 nutrients — worth a chat with your pharmacist, not a cause for alarm.

CALCIUM Insignificant Depletion FOLIC ACID Insignificant Depletion IRON Insignificant Depletion ZINC Insignificant Depletion VITAMIN B12 Moderate Depletion +1 more

🧪 Full Famotidine nutrient depletion report →

An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.

Where does this data come from?

Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.

Where does this data come from?

Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?

No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.

Why might an inactive ingredient be missing?

Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.

Can inactive ingredients matter?

Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price system	Per g	Per package
Retail pharmacies payNADAC · weekly	Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo	No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly	No Part D plan price is available for this NDC in our data.

ℹ️

No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.

Where does this data come from?

NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

Product	Labeler	Pack	NADAC/unit	TE	Status	Price vs. this
Famotidine 1 kg/kg 51927-0325-00	PROFESSIONAL	1 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 53069-0210-05	Quimica	20 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 70910-0002-00	Orchev	5 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 49711-0098-00	Uquifa	25 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 55111-0012-00	Dr.Reddy's	1 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 63126-0907-01	Yung	10 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 65841-0135-05	Zydus	25 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 45541-1175-00	Gedeon	1 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 65977-0125-01	Hetero	25 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 72375-0003-08	Haleos	25 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 72375-0008-01	Haleos	25 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 12836-0307-01	Ercros	25 kg	—	—	FDA listed	—
Famotidine 1 kg/kgthis 51927-3408-00	Professional	1 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 67835-0021-01	SMS	25 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 53069-0570-05	Quimica	20 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 67835-5012-01	SMS	1 kg	—	—	FDA listed	—
Famotidine 1 kg/kg 72640-0018-01	MSN	50 kg	—	—	FDA listed	—

About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.

Where does this data come from?

Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️

2002

On the market since

Jul 2002

📍

2026

Currently FDA-listed

24 years listed

🔒

·

No generic listed yet

brand only

ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?

Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📊 Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Famotidine (matched by generic name) — the program that covers self-administered drugs. 29 manufacturers.

⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Famotidine. CMS lists 2 products for this generic; we show the highest-spend one. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.

Period

Total Part D spend

$40.22M

Claims incl. refills

3.8M

Beneficiaries

2.6M

Spend / beneficiary

$15.35

Spend / claim

$10.62

Trend by period

💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

📦 Packaging — all sizes for this product

Package NDC	Description	Marketing start	Status
51927-3408-00 You're viewing this	1 kg in 1 CONTAINER (51927-3408-0)	—	Active

🧭 About this NDC listing & data coverage

Bulk ingredient (not a finished retail product)

This is a bulk ingredient listing — not a retail prescription package

FAMOTIDINE 1 kg/kg POWDER is listed with FDA as a bulk ingredient (a drug substance supplied for further manufacturing or licensed pharmacy compounding). It is not a finished product a patient would receive at a retail pharmacy, so consumer-style information — a patient label, retail pricing, package photos — generally does not exist for this NDC. The listing identifies the substance and package for supply-chain and regulatory purposes.

What data is (and isn’t) available for this NDC — tap to expand

NDC identity (package / product / labeler codes)	✓ Available
Labeler	✓ Available
Product & package description	✓ Available
Marketing category & status	✓ Available
Active ingredient / dosage form / route	✓ Available
FDA label (SPL via DailyMed)	✓ Available
Package photos	— Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured)	— Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS)	— Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data	— Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk	— Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD)	— Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.

“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?

An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Bulk Ingredient For Human Prescription Compounding". Products approved under an application carry an NDA, ANDA, or BLA number.

Why is there no price listed?

The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.

Can I get this product filled at a pharmacy?

Not as listed here. A bulk ingredient NDC identifies drug substance supplied for manufacturing or licensed compounding — it is not a finished, dispensable package. A pharmacy prescription would involve a finished product with its own NDC.

Is the NDC printed on the package the same as the 11-digit billing NDC?

Yes, they identify this exact package in different formats. The FDA registers it as 51927-3408-0, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 51927-3408-00, written without dashes as 51927340800. The Identity section at the top of this page lists every form of this code.

What do the three segments of this NDC mean?

In 51927-3408-00, the first segment (51927) is the labeler code FDA assigned to Professional Compounding Centers of America dba PCCA; the middle segment (3408) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (00) identifies this exact package size and type. Together they name one specific package of one specific product.

Is this package still being marketed?

Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Professional Compounding Centers of America dba PCCA. Listing status can change — the directory data on this page refreshes weekly.

Who lists this product with the FDA?

Professional Compounding Centers of America dba PCCA is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.

This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.

Where does this data come from?

Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 Full FDA label FDA SPL

The complete FDA label for this product, verbatim, section by section. Jump with a chip, search within the label, or expand everything.

📄 FDA label

📄 FDA label 19 words ▾

No FDA label is on file for this product yet. Labels load from openFDA / DailyMed and refresh weekly.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

🔗 Related NDC lookups

🧪 All Famotidine NDCsSame ingredient 🏭 All Professional labeler NDCsLabeler code 51927 📖 Read the Famotidine drug informationUses, warnings & side effects

💊 Related drugs in this class

Other drugs that share this product’s specific therapeutic class — Bulk Chemicals.

Papaverine Hcl 10695-0116-10 Dihydroergotamine Mesylate 38779-0303-03 Diazoxide 38779-0324-03 Beclomethasone Dipropionate 38779-0364-01 Caffeine 38779-0419-05 Enalapril Maleate 38779-0514-04 Clonidine Hcl 38779-0561-01 Minoxidil 38779-0574-01 Theophylline Anhydrous 38779-1816-01 Hydralazine Hcl 49452-3544-01 Quinidine Sulfate 49452-6180-01 Dipyridamole 51927-1571-00 Mexiletine Hcl 51927-2953-00 Ipratropium Bromide 51927-4783-00 Prazosin Hcl 51927-5040-00

Where does this data come from?

Other drugs sharing this product’s First Databank therapeutic class (HIC3). Each links to that NDC’s page in our directory.