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PERIOSCIENCES White Care AO Pro SODIUM FLUORIDE .24 mg/100mL Paste, Dentifrice — NDC 53238-001-90 (Billing 53238-0001-90)

by PERIOSCIENCES LLC · 1 TUBE in 1 CARTON / 90 mL in 1 TUBE

This is a package of PERIOSCIENCES White Care AO Pro SODIUM FLUORIDE .24 mg/100mL Paste, Dentifrice from PERIOSCIENCES LLC, marketed since Sep 2012 and currently FDA-listed. It is this product's only package size.

NDC 53238-0001-90
🏷️ FDA NDC (as labeled) 53238-001-90 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 53238-001-90
Product NDC 53238-001
11-digit billing NDC 53238000190
RxCUI 416783
UNII 8ZYQ1474W7
Application # M021
SPL Set ID 092bdfa3-6267-439e-9320-e51b4805d1a1
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2012-09-13
Route DENTAL
Dosage form PASTE, DENTIFRICE
Substance SODIUM FLUORIDE
Quick answers
  • RxCUI (RxNorm): 416783
Why two NDCs? The FDA registers this code as 53238-001-90 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 53238-0001-90. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Caries prophylactic agents class.

Drug family (ATC) Caries prophylactic agents, Fluoride
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

🧪 What is this product?

Periosciences White Care AO Pro is a fluoride toothpaste sold as an over-the-counter drug under FDA's monograph rules for dental care products. It contains sodium fluoride, which is commonly used in toothpastes and dental products to help strengthen tooth enamel and reduce cavities. This paste is applied topically to teeth during brushing as part of regular oral hygiene routines.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
53238-0001-90 You're viewing this Main listing 1 TUBE in 1 CARTON / 90 mL in 1 TUBE 2012-09-13 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
BIOTENE Gentle Mint 1.5 mg/g 00135-0558-01 Haleon 1 tube — — FDA listed —
TheraBreath Fresh Breath Anticavity Mild Mint .24 g/100g 10237-0263-04 Church 1 tube — — FDA listed —
Therabreath Whitening .243 g/100g 10237-0272-04 Church 1 tube — — FDA listed —
AIM Bubble Berry 2.4 mg/g 10237-0625-44 Church 1 tube — — FDA listed —
AIM CAVITY PROTECTION Multi Benefit 2.4 mg/g 10237-0633-55 Church 1 tube — — FDA listed —
AIM TARTAR CONTROL Plus Mouthwash and Whitening 2.4 mg/g 10237-0635-55 Church 1 tube — — FDA listed —
AIM Whitening with Baking Soda 2.4 mg/g 10237-0636-45 Church 1 tube — — FDA listed —
CLOSE UP Freshening with Mouthwash 2.4 mg/g 10237-0644-40 Church 1 tube — — FDA listed —
Pepsodent Complete Care Original 2.4 mg/g 10237-0651-55 Church 1 tube — — FDA listed —
Peroxicare 2.4 mg/g 10237-0655-12 Church 2 tubes — — FDA listed —
Advance White Tartar Control Breath Freshening 2.4 mg/g 10237-0656-60 Church 1 tube — — FDA listed —
Advance White Extreme Whitening Tartar Control 2.4 mg/g 10237-0658-09 Church 1 tube — — FDA listed —
Enamel Defense .24 mg/g 10237-0666-09 Church 1 tube — — FDA listed —
Essentials Healthy Teeth and Gums 2.4 mg/g 10237-0670-09 Church 1 tube — — Discontinued —
Essentials Whiten and Strengthen 2.4 mg/g 10237-0672-09 Church 1 tube — — Discontinued —
Complete Care Whole Mouth Protection 1.5 mg/g 10237-0675-09 Church 1 tube — — FDA listed —
A and H Plus Therabreath Breath Freshners .243 g/100g 10237-0676-55 Church 156 g — — FDA listed —
Arm and Hammer 2.4 mg/g 10237-0679-06 Church 1 tube — — FDA listed —
Arm and Hammer 2.4 mg/g 10237-0680-06 Church 1 tube — — FDA listed —
Orajel Kids Superman 1.5 mg/g 10237-0732-42 Church 119 g — — FDA listed —
Orajel SuperMario 2.4 mg/g 10237-0733-42 Church 119 g — — FDA listed —
Orajel Toy Story 5 Anticavity 1.5 mg/g 10237-0734-42 Church 119 g — — FDA listed —
Orajel KidsToothpaste 1.5 mg/g 10237-0785-42 Church 119 g — — FDA listed —
Orajel Paw Patrol 1.5 mg/g 10237-0786-42 Church 119 g — — FDA listed —
Orajel Gabbys Dollhouse 2.4 mg/g 10237-0914-42 Church 119 g — — FDA listed —
Colgate MaxFresh with Mini Breath Clean Mint 1.1 mg/g 35000-0013-34 Colgate-Palmolive 2 tubes — — Discontinued —
Colgate MaxFresh with Mini Breath Cool Mint 1.1 mg/g 35000-0014-34 Colgate-Palmolive 2 tubes — — Discontinued —
Colgate Kids Cavity Protection 1.1 mg/g 35000-0015-32 Colgate-Palmolive 90 g — — FDA listed —
Colgate Kids Harry Potter 1.1 mg/g 35000-0016-46 Colgate-Palmolive 130 g — — FDA listed —
Colgate MaxClean with Whitening Smartfoam 1.1 mg/g 35000-0028-60 Colgate-Palmolive 1 tube — — Discontinued —
Colgate MaxFresh Knockout 1.1 mg/g 35000-0127-60 COLGATE 1 tube — — Discontinued —
Colgate MaxFresh Citrus Fresh 1.1 mg/g 35000-0137-48 Colgate-Palmolive 1 tube — — FDA listed —
Colgate MaxFresh Watermelon Blast 1.1 mg/g 35000-0138-48 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Kids Maximum Cavity Protection 1.1 mg/g 35000-0190-44 Colgate-Palmolive 124 g — — FDA listed —
Colgate Maximum Cavity Protection Bubble Fruit Flavor 1.1 mg/g 35000-0196-44 Colgate-Palmolive 124 g — — FDA listed —
Colgate Kids Space Jam Mild Bubble Fruit Flavor 1.1 mg/g 35000-0199-44 Colgate-Palmolive 124 g — — FDA listed —
Colgate MaxFresh Cool Mint 1.1 mg/g 35000-0211-30 COLGATE 1 cello — — FDA listed —
Colgate MaxFresh Clean Mint 1.1 mg/g 35000-0212-30 Colgate-Palmolive 1 cello — — FDA listed —
Colgate MaxFresh Charcoal 1.1 mg/g 35000-0213-95 Colgate-Palmolive 1 tube — — FDA listed —
Colgate MaxFresh Knockout 1.1 mg/g 35000-0214-30 Colgate-Palmolive 1 cello — — FDA listed —
Colgate Kids Llama Mild Bubble Fruit Flavor 1.1 mg/g 35000-0365-44 Colgate-Palmolive 124 g — — FDA listed —
Colgate Ultra White Charcoal 1.1 mg/g 35000-0418-98 Colgate-Palmolive 1 tube — — FDA listed —
TP COL OW Purple 1.1 mg/g 35000-0419-71 Colgate-Palmolive 1 tube — — FDA listed —
Colgate MaxFresh Clean Mint 1.1 mg/g 35000-0430-58 Colgate-Palmolive 1 tube — — FDA listed —
Hello Dragon Dazzle Dragon Dazzle Fluoride 1.5 mg/g 35000-0679-10 Colgate-Palmolive 1 tube — — FDA listed —
Hello Magical Mermaid 1.1 mg/g 35000-0680-10 Colgate-Palmolive 119 g — — FDA listed —
Hello Unicorn Sparkle 1.1 mg/g 35000-0686-10 Colgate-Palmolive 1 tube — — FDA listed —
Hello Kids Wild Strawberry Wild Strawberry 1.5 mg/g 35000-0688-10 Colgate-Palmolive 1 tube — — FDA listed —
Hello Vitamin C Whitening 1.5 mg/g 35000-0689-10 Colgate-Palmolive 1 tube — — FDA listed —
Hello Penguin Chill 1.1 mg/g 35000-0693-12 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Max Fresh Coconut Pineapple 2.4 mg/g 35000-0789-86 Colgate-Palmolive 1 tube — — FDA listed —
Optic White Non-Hp Stain Fighter Clean Mint 1.1 mg/g 35000-0793-38 Colgate-Palmolive 2 tubes — — FDA listed —
Colgate Optic White Purple 1.1 mg/g 35000-0796-59 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Optic White Non-Hp Stain Fighter Fresh Mint 1.1 mg/g 35000-0797-59 Colgate-Palmolive 1 tube — — Discontinued —
Colgate Optic White Charcoal 1.1 mg/g 35000-0798-59 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Optic White Relief 1.1 mg/g 35000-0799-59 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Optic White Stain Fighter With Baking Soda 1.1 mg/g 35000-0809-42 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Max Fresh Advanced Whitening 2.4 mg/g 35000-0899-34 Colgate-Palmolive 2 tubes — — Discontinued —
Colgate Sparkling White Cinnamint 1.1 mg/g 35000-0900-60 Colgate-Palmolive 1 tube — — Discontinued —
Colgate Max Fresh Cool Mint 1.1 mg/g 35000-0903-01 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Kids Watermelon Flavor 1.1 mg/g 35000-0905-81 Colgate-Palmolive 130 g — — Discontinued —
Colgate 2In1 Whitening Stain Lifters 1.1 mg/g 35000-0907-81 Colgate-Palmolive 130 g — — Discontinued —
Colgate Strawberry Burst 1.1 mg/g 35000-0915-46 Colgate-Palmolive 130 g — — FDA listed —
Colgate Ultra Brite Advanced Whitening All In One Clean Mint 1.1 mg/g 35000-0917-60 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Kids Mild Bubble Fruit Flavor 1.1 mg/g 35000-0918-46 Colgate-Palmolive 130 g — — FDA listed —
Colgate Junior Bubble Fruit 1.1 mg/g 35000-0926-20 COLGATE 1 tube — — Discontinued —
Colgate 2In1 Icy Blast 1.1 mg/g 35000-0927-81 Colgate-Palmolive 130 g — — FDA listed —
Colgate Optic White Stain Fighter Fresh Mint 1 mg/g 35000-0936-02 COLGATE 1 tube — — FDA listed —
Colgate Optic White Stain Fighter Clean Mint 1 mg/g 35000-0937-02 COLGATE 1 tube — — Discontinued —
Colgate Triple Action 1.1 mg/g 35000-0941-46 Colgate-Palmolive 1 tube — — Discontinued —
Colgate Max Fresh Cool Mint 1.1 mg/g 35000-0947-81 Colgate-Palmolive 130 g — — FDA listed —
Colgate Junior Kids Batman Mild Bubble Fruit Fluoride 1.1 mg/g 35000-0950-46 Colgate-Palmolive 130 g — — FDA listed —
Colgate Cavity Protection 1.1 mg/g 35000-0953-71 Colgate-Palmolive 119 g — — FDA listed —
Colgate Junior Mixed Kids Bubble Fruit Fluoride 1.1 mg/g 35000-0958-46 Colgate-Palmolive 130 g — — Discontinued —
Colgate Deep Clean Fluoride 1.1 mg/g 35000-0969-58 Colgate-Palmolive 1 tube — — FDA listed —
Colgate Minions Mild Bubble Fruit Fluoride 1.1 mg/g 35000-0971-46 Colgate-Palmolive 130 g — — FDA listed —
Colgate Optic White Charcoal 1.1 mg/g 35000-0988-71 Colgate-Palmolive 1 tube — — FDA listed —
Colgate MaxFresh Charcoal 1.1 mg/g 35000-0990-34 Colgate-Palmolive 2 tubes — — Discontinued —
TP OW Stainfighter Clean Mint 1.1 mg/g 35000-0999-34 Colgate-Palmolive 1 tube — — FDA listed —
ACT Anticavity Fluoride Kids Wild Watermelon 1.4 mg/g 41167-0924-02 Chattem, 130 g — — FDA listed —
ACT Kids Anticavity Fluoride Groovy Grape 1.4 mg/g 41167-0926-01 Chattem, 130 g — — FDA listed —
Beyond Activated Coconut Charcoal and Sea Salt .24 g/100g 42199-0008-04 Beyond 1 tube — — FDA listed —
Natural Fluoride Fresh Mint cavity protection whitening fresh breath .00243 g/g 51009-0238-59 Tom's 85 g — — FDA listed —
Simply White Clean Mint .00243 g/g 51009-0248-47 Tom's 1 tube — — Discontinued —
Toms Of Maine Activated Charcoal Peppermint 1.1 mg/g 51009-0900-40 Tom's 1 tube — — FDA listed —
Toms of Maine Whiten Plus Deep Clean Peppermint 1.1 mg/g 51009-0920-40 Tom's 1 tube — — FDA listed —
Toms Of Maine Whiten Plus Deep Clean Spearmint 1.1 mg/g 51009-0921-40 Tom's 1 tube — — FDA listed —
Opalescence Whitening Cool Mint 1.1 mg/g 51206-0314-01 Ultradent 1 tube — — FDA listed —
Euthymol Whitening Purple Corrector 1.5 mg/g 53208-0563-65 LG 1 tube — — FDA listed —
PERIOSCIENCES White Care AO Pro .24 mg/100mLthis 53238-0001-90 PERIOSCIENCES 1 tube — — FDA listed —
Koala Pals Berrylicious .2592 g/108g 54473-0300-04 Melaleuca, 108 g — — FDA listed —
OralLine Secure .15 g/100g 55873-0001-01 J.M. 85 g — — FDA listed —
OralLine .15 g/100g 55873-0002-01 J.M. 85 g — — FDA listed —
OralLine Kids .15 g/100g 55873-0003-01 J.M. 113.4 g — — FDA listed —
OralLine Kids .15 g/100g 55873-0004-01 J.M. 113.4 g — — FDA listed —
CloSYS 1.1 mg/g 58578-0749-01 Rowpar 1 tube — — FDA listed —
Kids Kare 2.4 mg/g 59883-0718-04 DEN-MAT 113.4 g — — FDA listed —
Gel 1100 Mint 1100 ug/g 61578-0213-01 Dental 68 g — — FDA listed —
Gel 1100 Citrus 1100 ug/g 61578-0214-01 Dental 68 g — — FDA listed —
Gel 1100 Grape 1100 ug/g 61578-0217-01 Dental 68 g — — FDA listed —
MIPasteOne Kids Blue Raspberry .24 g/100g 61596-0100-10 GC 1 tube — — FDA listed —
MIPaste One Kids Bubble Gum .24 g/100g 61596-0101-10 GC 1 tube — — FDA listed —
MIPaste One Kids Cotton Candy .24 g/100g 61596-0102-10 GC 1 tube — — FDA listed —
MIPaste One Kids Blue Raspberry .24 g/100g 61596-0103-10 GC 10 bottles — — FDA listed —
Made by Dentists For Kids Cheetah Dust 1.5 mg/g 62776-0000-01 Fulijaya 1 tube — — FDA listed —
Made by Dentists For Kids Eyeball Juice 1.5 mg/g 62776-0001-01 Fulijaya 1 tube — — FDA listed —
Made by Dentists For Kids Monster Slime 1.5 mg/g 62776-0002-01 Fulijaya 1 tube — — FDA listed —
Made by Dentists Ultra Whitening Professional 1.5 mg/g 62776-0005-01 Fulijaya 1 tube — — FDA listed —
Made by Dentist For Kids Chew Toy Bubblegum 1.5 mg/g 62776-0006-01 Fulijaya 1 tube — — FDA listed —
Colgate Sparkling White Cinnamint 1.1 mg/g 65954-0008-69 Mission 1 tube — — FDA listed —
Colgate Max Fresh Cool Mint 1.1 mg/g 65954-0014-01 Mission 1 tube — — FDA listed —
Colgate Kids Watermelon Flavor 1.1 mg/g 65954-0036-81 Mission 130 g — — Discontinued —
Colgate 2In1 Whitening Stain Lifters 1.1 mg/g 65954-0038-81 Mission 130 g — — FDA listed —
Colgate Cavity Protection Fresh Mint 1.1 mg/g 65954-0061-69 Mission 113 g — — Discontinued —
Colgate Ultra Brite Advanced Whitening All In One Clean Mint 1.1 mg/g 65954-0064-60 Mission 1 tube — — FDA listed —
Colgate Kids Mild Bubble Fruit Flavor 1.1 mg/g 65954-0065-46 Mission 130 g — — FDA listed —
Colgate Junior Bubble Fruit 1.1 mg/g 65954-0327-20 Mission 1 tube — — FDA listed —
Colgate 2In1 Icy Blast 1.1 mg/g 65954-0355-81 Mission 130 g — — FDA listed —
Colgate Optic White Stain Fighter Fresh Mint 1 mg/g 65954-0402-02 Mission 1 tube — — FDA listed —
Colgate Optic White Stain Fighter Clean Mint 1 mg/g 65954-0403-02 Mission 1 tube — — Discontinued —
Colgate Triple Action 1.1 mg/g 65954-0536-30 Mission 3 tubes — — FDA listed —
Colgate Max Fresh Cool Mint 1.1 mg/g 65954-0564-81 Mission 130 g — — FDA listed —
Colgate Junior Kids Batman Mild Bubble Fruit Fluoride 1.1 mg/g 65954-0585-46 Mission 130 g — — FDA listed —
Colgate Cavity Protection 1.1 mg/g 65954-0591-71 Mission 119 g — — FDA listed —
Colgate Junior Mixed Kids Bubble Fruit Fluoride 1.1 mg/g 65954-0607-46 Mission 1 tube — — FDA listed —
Colgate Deep Clean Fluoride 1.1 mg/g 65954-0777-58 Mission 1 tube — — FDA listed —
Colgate Minions Mild Bubble Fruit Fluoride 1.1 mg/g 65954-0779-46 Mission 130 g — — FDA listed —
Colgate Optic White Stain Fighter with Baking Soda 1.1 mg/g 65954-0810-42 Colgate-Palmolive 1 tube — — FDA listed —
TP COL OW Purple 1.1 mg/g 65954-0825-58 Mission 1 tube — — FDA listed —
Colgate Max Fresh Clean Mint 1.1 mg/g 65954-0831-58 Colgate-Palmolive 1 tube — — FDA listed —
Colgate 2 In 1 Kids Sp Strawberry 1.1 mg/g 65954-0832-46 Mission 130 g — — FDA listed —
Colgate Optic White Charcoal 1.1 mg/g 65954-0835-59 Mission 1 tube — — FDA listed —
Colgate Optic White Non-Hp Stain Fighter Fresh Mint 1.1 mg/g 65954-0836-59 Mission 1 tube — — FDA listed —
Colgate Optic White Purple 1.1 mg/g 65954-0837-59 Mission 1 tube — — FDA listed —
Colgate Optic White Non-Hp Stain Fighter Clean Mint 1.1 mg/g 65954-0840-38 Mission 2 tubes — — FDA listed —
Firefly Bubble Gum natural fluoride .24 g/100g 66923-0119-00 Ranir 119 g — — FDA listed —
Firefly Strawberry Natural Fluoride .24 g/100g 66923-0201-00 Ranir 119 g — — FDA listed —
Firefly Bubble Gum natural fluoride .24 g/100g 66923-0323-00 Ranir 119 g — — FDA listed —
Pro-Sys .11 g/100g 66975-0700-01 Benco 113.4 g — — FDA listed —
Pro-Sys .11 g/100g 66975-0720-01 Benco 113.4 g — — FDA listed —
Quip Anticavity .24 g/100g 69261-0006-01 Quip 1 tube — — FDA listed —
Quip Anticavity .24 g/100g 69261-0007-01 Quip 1 tube — — FDA listed —
Crest Complete plus Whitening Deep Clean 1.5 mg/g 69423-0911-54 The 1 tube — — FDA listed —
evo ADVANCED WHITENING ANTI-CAVITY FLUORIDE PEPPERMINT .24 g/100g 70108-0204-01 Ashtel 1 tube — — FDA listed —
Brush Buddies ADVANCED WHITENING ANTI-CAVITY FLUORIDE PEPPERMINT .24 g/100g 70108-0205-01 Ashtel 1 tube — — FDA listed —
Plak Smacker Anti Cavity Fluoride 1.4 mg/g 72326-8002-01 YOUNG 24 g — — FDA listed —
Plak Smacker GREAT WHITE SHARK 1.4 mg/g 72326-8003-01 YOUNG 120 g — — FDA listed —
Eurofresh Whitening 1.08 mg/g 74690-0008-01 Farmasi 1 tube — — FDA listed —
Farmasi Whitening 1.5 mg/g 74690-0012-01 Farmasi 1 tube — — FDA listed —
Made By Dentists, Inc. Whitening .24 g/100g 75065-0017-06 Made 1 tube — — Discontinued —
Made By Dentists, Inc. Total Care .24 g/100g 75065-0018-06 Made 1 tube — — Discontinued —
Made By Dentists, Inc. Alien Blood .24 g/100g 75065-0020-06 Made 1 tube — — Discontinued —
Made By Dentists, Inc. Monster Slime .24 g/100g 75065-0021-06 Made 1 tube — — Discontinued —
Made by Dentists For Kids Monster Slime Sour Apple 1.5 mg/g 75065-0023-06 MADE 1 tube — — FDA listed —
Made by Dentists For Kids Eyeball Juice (Watermelon) 1.5 mg/g 75065-0024-06 MADE 1 tube — — FDA listed —
Made by Dentists For Kids Cheetah Dust (Strawberry) 1.5 mg/g 75065-0025-06 MADE 1 tube — — FDA listed —
Made by Dentists For Kids Alien Blood 1.5 mg/g 75065-0026-06 MADE 1 tube — — Discontinued —
Made by Dentists Ultra Whitening Fresh Mint 1.5 mg/g 75065-0027-06 MADE 1 tube — — FDA listed —
Made by Dentists For Kids Eyeball Juice (Watermelon) 1.5 mg/g 75065-0030-07 MADE 1 tube — — FDA listed —
Made by Dentist for Kids Chew Toy (Bubblegum) 1.5 mg/g 75065-0031-06 MADE 1 tube — — FDA listed —
Made by Dentists for Kids Fluoride Anticavity Bamboolicious (Bubblegum) 1.5 mg/g 75065-0032-06 Made 1 tube — — FDA listed —
Freshen Up Vanilla Mint .24 g/100g 77782-0006-20 MKJ 1 bottle — — FDA listed —
Freshen Up Holiday mint .24 g/100g 77782-0007-20 MKJ 1 bottle — — FDA listed —
Freshen Up pepper mint .24 g/1000g 77782-0008-20 MKJ 1 bottle — — FDA listed —
Freshen Up twisted peppermint .24 g/100g 77782-0010-20 MKJ 1 bottle — — FDA listed —
Freshen-up Matcha Mint .24 g/100g 77782-0011-20 MKJ 1 bottle — — FDA listed —
Freshen Up chai latte mint .24 g/1000g 77782-0012-20 MKJ 1 bottle — — FDA listed —
Moon Platinum Advanced Whitening Anticavity .24 g/100g 82214-0001-02 Moon 1 tube — — FDA listed —
Moon Charcoal Whitening Anticavity .24 g/100g 82214-0003-02 Moon 1 tube — — FDA listed —
Moon Whitening Gel Anticavity .24 g/100g 82214-0004-02 Moon 1 tube — — FDA listed —
Hismile 2.4 mg/g 83013-0311-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0312-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0313-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0314-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0315-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0316-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0317-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0318-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0319-06 Hismile 60 g — — FDA listed —
Hismile 2.4 mg/g 83013-0320-06 Hismile 60 g — — FDA listed —
Hismile .243 g/100g 83013-0321-06 HISMILE 60 g — — FDA listed —
Hismile .243 g/100g 83013-0322-06 HISMILE 60 g — — FDA listed —
Hismile .243 g/100g 83013-0323-06 HISMILE 60 g — — FDA listed —
Hismile .243 g/100g 83013-0325-06 HISMILE 60 g — — FDA listed —
Hismile .243 g/100g 83013-0326-06 HISMILE 60 g — — FDA listed —
Hismile .243 g/100g 83013-0327-06 HISMILE 60 g — — FDA listed —
Ice Pop Flavor Sodium Fluoride Anticavity Toothpast .243 g/100g 83013-0328-06 HISMILE 60 g — — FDA listed —
Hismile Grape Bubblegum Flavor Sodium Fluoride Anticavity Toothpast .243 g/100g 83013-0331-06 Hismile 60 g — — FDA listed —
Hismile Pink Lemonade Sodium Fluoride Anticavity Toothpast .243 g/100g 83013-0332-06 Hismile 60 g — — FDA listed —
Hismile Miffy Sweet Apple Flavor Sodium Fluoride Anticavity Toothpast .243 g/100g 83013-0333-06 Hismile 60 g — — FDA listed —
Hismile .243 g/100g 83013-0335-06 Hismile 60 g — — FDA listed —
The Simpsons Purple Squishee Flavor Sodium Fluoride Anticavity Toothpast .243 g/100g 83013-0346-06 HISMILE 60 g — — FDA listed —
Enamur Fluoride AntiCavity Toothpast 1.4 mg/g 83610-1050-01 Protegera, 1 tube — — FDA listed —
OraPro Fluoride Anticavity 1.4 mg/g 83610-1060-01 Protegera, 1 tube — — FDA listed —
Dubai Chocolate Flavor 2.4 mg/g 83729-0119-10 SuperMouth, 1 tube — — FDA listed —
Super Mint .24 mg/100g 83729-0121-10 SuperMouth, 1 tube — — FDA listed —
Dentalclean Ultra Refreshing Extreme Ice Dental Gel 2.4 mg/g 84035-0001-01 Rabbit 1 tube — — FDA listed —
Dentalclean Regenerator Sensitive Dental Gel with Fluoride 2.4 mg/g 84035-0002-03 Rabbit 1 tube — — FDA listed —
Dentalclean Sensitive Plus 2.4 mg/g 84035-0003-03 Rabbit 1 tube — — FDA listed —
Dentalclean Whitening Max 2.4 mg/g 84035-0004-03 Rabbit 1 tube — — FDA listed —
Dentalclean Regenerator Sensitive Kids 2.4 mg/g 84035-0005-03 Rabbit 1 tube — — FDA listed —
Dentalclean Dental Gel Booster Adult Use 2.4 mg/g 84035-0006-20 Rabbit 1 tube — — FDA listed —
Dentalclean Booster Kids 2.4 mg/g 84035-0007-20 Rabbit 1 tube — — FDA listed —
Dentalclean Doctor Duck 2.4 mg/g 84035-0008-50 Rabbit 1 tube — — FDA listed —
Dentalclean Advanced Pro 2.4 mg/g 84035-0013-06 Rabbit 1 tube — — FDA listed —
Plak Smacker Great White Shark Cool Berry Flavor Anti Cavity Fluoride Gel Tooth .1 g/100g 85162-0003-01 Yangzhou 144 tubes — — FDA listed —
Sexyteeth Charcoal T00Thpaste .24 g/100g 85215-0003-01 WORLD 113 g — — FDA listed —
Sexyteeth Minty T00Thpaste .24 g/100g 85215-0004-01 WORLD 113 g — — FDA listed —
Smile Paint 87245-0001-01 JABBER 1 kit — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2012
On the market since
Sep 2012
📍
2026
Currently FDA-listed
14 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 00YIU5438U
    Caprylyl glycol is a clear liquid derived from coconut oil. In medicines, it acts as a humectant to retain moisture, a preservative booster to prevent microbial growth, and a solvent to help dissolve or mix other ingredients.
  • UNII K679OBS311
    Carboxymethylcellulose sodium is a plant-derived thickening agent made from cellulose. In medicines, it acts as a binder to hold ingredients together, a disintegrant to help the tablet break apart, or a thickener in liquids.
  • UNII 5OCF3O11KX
    A plant-derived surfactant made from coconut oil. It helps mix oil and water ingredients together in the formulation and can improve how the medicine spreads or feels on the skin.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII AVM951ZWST
    Ferulic acid is a naturally occurring plant compound used as an antioxidant in medications. It helps prevent ingredient breakdown and maintain product stability during storage.
  • UNII Q9Q3D557F1
    Hesperetin is a plant-derived compound from citrus fruits. It's used in formulations as an antioxidant to help protect the medicine's active ingredients from degradation during storage.
  • UNII Y6O7T4G8P9
    Hydrated silica is a fine powder form of silicon dioxide with absorbed water. It works as an anti-caking agent and absorbent in medicines, helping powders stay free-flowing and preventing clumping.
  • UNII L7T10EIP3A
    A cooling compound from mint plants used as a flavoring agent and to create a fresh sensation in medicines. It helps mask bitter tastes and improve how the product feels in the mouth.
  • UNII AV092KU4JH
    A natural oil extracted from peppermint plants. It's used as a flavoring agent to mask bitter tastes and add a refreshing mint flavor to medicines, making them easier to take.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII S5J5OE47MK
    Phloretin is a natural compound found in apple trees and related plants. In medications, it's used as an antioxidant ingredient to help protect the product from degradation and maintain stability during storage.
  • UNII 1VPU26JZZ4
    Potassium sorbate is a salt derived from sorbic acid, a naturally occurring preservative. It prevents growth of mold, yeast, and some bacteria, extending the medicine's shelf life.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII ET1TN5W71X
    Pummelo is a citrus fruit extract used as a natural flavoring and fragrance agent. It adds taste and aroma to medicines, making them more pleasant to take.
  • UNII 836SJG51DR
    Sodium ascorbyl phosphate is a derivative of vitamin C that acts as an antioxidant and preservative in medications. It helps protect the drug's active ingredients from degradation caused by air and light exposure.
  • UNII 1Q73Q2JULR
    Sodium citrate is a salt derived from citric acid. It works as a buffer to maintain the medicine's pH level and may also help improve taste or act as a preservative in the formulation.
  • UNII JVL98CG53G
    Sodium methyl cocoyl taurate is a mild, plant-derived cleaning agent made from coconut oil and an amino acid. It's used in liquid formulations as a surfactant to help mix oil and water-based ingredients together and improve how the medicine spreads or is absorbed.
  • UNII P1BM4ZH95L
    A salt derived from phosphoric acid, sodium polymetaphosphate acts as a sequestrant and buffering agent in medicines. It helps maintain stability and control acidity in liquid formulations.
  • UNII 506T60A25R
    Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
  • UNII 6U422Y08O2
    A natural sweetener derived from stevia plant leaves. It provides sweetness to the medicine with minimal calories and is used to improve taste, making the medication more palatable.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
  • UNII 91D9GV0Z28
    A mineral salt made from calcium and phosphate. It acts as a filler to add bulk to the tablet or capsule, and helps bind ingredients together so the medicine holds its shape.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

23 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesglycerin, aqua (water), hydrated silica, sorbitol, propylene glycol, sodium methyl cocoyl taurate, pvp, hydroxyapatite, cocamidopropyl betaine, ferulic acid, phloretin, hesperetin, menthol, mentha piperita (peppermint) oil, sodium ascorbyl phosphate, sodium olivoyl glutamate, citrus grandis (grapefruit) fruit extract, stevia rebaudiana bertoni, sodium citrate, ethylhexylglycerin, cellulose gum, potassium sorbate, titanium dioxide, phenoxyethanol, sodium polyphosphate, caprylyl glycol

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerPERIOSCIENCES LLC
FDA applicationM021 (OTC MONOGRAPH DRUG)
Labeler code53238
First marketedSep 2012
Product typeHuman Otc Drug
Portfolio3 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 7 words ▾

Uses Aids in prevention of dental cavities.

⏱️ Dosage and Administration 68 words ▾

Directions Adults and children 2 years of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or doctor. Instruct children under 6 years of age in good brushing and rinsing habits (to minimize swallowing). Supervise children as necessary until capable of using without supervision. Children under 2 years of age: Ask a dentist or physician

⚠️ Warnings 32 words ▾

Warning Keep out of reach of children under 2 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 9 words ▾

Active ingredient Sodium fluoride 0.24% (0.15% w/v fluoride ion)

🧪 Inactive Ingredients 55 words ▾

Inactive ingredients glycerin, aqua (water), hydrated silica, sorbitol, propylene glycol, sodium methyl cocoyl taurate, pvp, hydroxyapatite, cocamidopropyl betaine, ferulic acid, phloretin, hesperetin, menthol, mentha piperita (peppermint) oil, sodium ascorbyl phosphate, sodium olivoyl glutamate, citrus grandis (grapefruit) fruit extract, stevia rebaudiana bertoni, sodium citrate, ethylhexylglycerin, cellulose gum, potassium sorbate, titanium dioxide, phenoxyethanol, sodium polyphosphate, caprylyl glycol

🎯 Purpose 2 words ▾

Purpose Anticavity

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for PERIOSCIENCES White Care AO Pro (this brand).

Top reported reactions

Pyrexia172
Weight Increased162
Nausea160
Vomiting159
Fatigue158
Pain158
Nasopharyngitis155

Reporter sex

0 reports
Male · 35%
Female · 65%
Unknown · 0%
Reports over time (by year) — tap or hover for the count & year
2020 2022 2024 2026 213 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by PERIOSCIENCES LLC. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
PERIOSCIENCES LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 53228-0232-01 · Equibal, 53238-0002-90 · PERIOSCIENCES →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.