Rest SILVER NITRATE,CAUSTICUM,MATRICARIA CHAMOMILLA,ANAMIRTA COCCULUS SEED,SODIUM CHLORIDE,PHOSPHORUS and VALERIAN 12 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 3 [hp_X]/1; 12 [hp_X]/1; 12 [hp_X]/1 Tablet, 50-count
by Hyland's Inc. · 1 BOTTLE, PLASTIC in 1 CARTON (54973-3332-1) / 50 TABLET in 1 BOTTLE, PLASTIC
NDC 54973-3332-01
🏷️ FDA NDC (as labeled)
54973-3332-1
billing pads the package segment with a zero
This package
Contains50-count
Pack sizes2 compare ↓
Also comes in:
4 tablets 54973-3332-02
OTC
On market
Non-controlled
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
54973-3332-1
Product NDC
54973-3332
11-digit billing NDC
54973333201
UNII
810258W28U, DD5FO1WKFU, JWF5YAW3QW, 95IT3W8JZE, G0R4UBI2ZZ, 451W47IQ8X +1 more
SPL Set ID
5e9924be-4dad-324a-e053-2a91aa0a8ec1
Established class (EPC)
Osmotic Laxative
Mechanism of action
Osmotic Activity
Physiologic effect
Increased Large Intestinal Motility; Inhibition Large Intestine Fluid/Electrolyte Absorption
DEA schedule
Non-controlled
Marketing category
UNAPPROVED HOMEOPATHIC
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2017-11-30
Route
ORAL
Dosage form
TABLET
Substance
ANAMIRTA COCCULUS SEED; CAUSTICUM; VALERIAN; SILVER NITRATE; MATRICARIA CHAMOMILLA; SODIUM CHLORIDE; PHOSPHORUS
Why two NDCs?
The FDA registers this code as 54973-3332-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 54973-3332-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏭 Manufacturer & labeler
LabelerHyland's Inc.
Labeler code54973
First marketedNov 2017
Product typeHuman Otc Drug
Portfolio69 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
🧪 What is this product?
Rest is an unapproved homeopathic tablet taken by mouth that contains seven ingredients traditionally used in homeopathic practice for relaxation and sleep support. The formula includes valerian and chamomile, herbs commonly featured in relaxation products, along with phosphorus, silver nitrate, and other substances selected according to homeopathic principles. Homeopathic products are marketed based on traditional use rather than clinical evidence, and this product has not been evaluated by the FDA for effectiveness.
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about SILVER NITRATE,CAUSTICUM,MATRICARIA CHAMOMILLA,ANAMIRTA COCCULUS SEED,SODIUM CHLORIDE,PHOSPHORUS and VALERIAN?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size:
4 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Rest 12 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 3 [hp_X]/1; 12 [hp_X]/1; 12 [hp_X]this 54973-3332-01 | Hyland's | 50 tablets | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2017
On the market since
Nov 2017
📍
2026
Currently FDA-listed
9 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 54973-3332-01 You're viewing this | 1 BOTTLE, PLASTIC in 1 CARTON (54973-3332-1) / 50 TABLET in 1 BOTTLE, PLASTIC | 2017-11-30 | Active |
| 54973-3332-02 | 4 TABLET in 1 POUCH (54973-3332-2) | 2017-11-30 | Active |
Pack size FAQ
What quantity is in NDC 54973-3332-01?
NDC 54973-3332-01 is a 50-count package — 1 bottle, plastic in 1 carton / 50 tablet in 1 bottle, plastic.
What is the difference between NDC 54973-3332-01 and NDC 54973-3332-02?
Both are Rest SILVER NITRATE,CAUSTICUM,MATRICARIA CHAMOMILLA,ANAMIRTA COCCULUS SEED,SODIUM CHLORIDE,PHOSPHORUS and VALERIAN 12 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 3 [hp_X]/1; 12 [hp_X]/1; 12 [hp_X]/1 Tablet — the drug itself is identical. NDC 54973-3332-01 is the 50-count package, while NDC 54973-3332-02 is the 4 tablets package.
What NDC number is used to bill for this package of Rest SILVER NITRATE,CAUSTICUM,MATRICARIA CHAMOMILLA,ANAMIRTA COCCULUS SEED,SODIUM CHLORIDE,PHOSPHORUS and VALERIAN 12 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 3 [hp_X]/1; 12 [hp_X]/1; 12 [hp_X]/1 Tablet?
Bill NDC 54973-3332-01 — the 11-digit billing format is 54973333201. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
Homeopathic listing
About homeopathic listings
Rest SILVER NITRATE,CAUSTICUM,MATRICARIA CHAMOMILLA,ANAMIRTA COCCULUS SEED,SODIUM CHLORIDE,PHOSPHORUS and VALERIAN 12 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 6 [hp_X]/1; 3 [hp_X]/1; 12 [hp_X]/1; 12 [hp_X]/1 TABLET is listed under the homeopathic marketing category. An NDC listing in this category does not by itself establish FDA approval, and FDA does not evaluate homeopathic products for effectiveness. This page reports the listing data as published.
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | — Not published for this NDC No photo available yet for this listing. |
| Inactive ingredients (structured) | — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available. |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Homeopathic". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 54973-3332-1, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 54973-3332-01, written without dashes as 54973333201. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 54973-3332-01, the first segment (54973) is the labeler code FDA assigned to Hyland's Inc.; the middle segment (3332) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Hyland's Inc.. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 4 tablets (54973-3332-02). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Hyland's Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses Temporarily relieves the symptoms of occasional sleeplessness, restlessness, irritability, anxiousness, nervousness, wakefulness and difficulty falling to sleep due to stress.
⏱️ Dosage and Administration ▾
Directions Adults & Children 12 years and over: Dissolve 2-3 tablets under tongue ½ hour to 1 hour before retiring. Children 6 years to under 12 years of age: Dissolve 1-2 tablets under tongue ½ hour to 1 hour before retiring.
⚠️ Warnings ▾
As with any drug, ask doctor before use if pregnant or breast-feeding. Do not use • more than directed • if you have a known allergy to any ingredient in this product. Consult a physician if symptoms persist for more than 7 days or worsen.
Keep this and all medications out of reach of children. In case of accidental overdose, contact a medical professional or Poison Control Center immediately. Do not use if imprinted tamper band is broken or missing.
In case of emergency Contact a medical professional or Poison Control Center immediately. Hyland’s may also be contacted for emergency information about our products 24 hours a day, 7 days per week at (800) 624-9659.
🧪 Active Ingredient ▾
Active Ingredients Purpose Argentum Nitricum 6X HPUS anxiousness, restlessness, nervousness due to stress Causticum 6X HPUS anxiousness, restlessness, and occasional sleeplessness Chamomilla 3X HPUS occasional sleeplessness Cocculus 12X HPUS wakefulness, anxiousness, restlessness and occasional sleeplessness Natrum Muriaticum 12X HPUS difficulty falling asleep, anxiousness due to stress Phosphorus 12X HPUS occasional sleeplessness, difficulty falling asleep due to stress Valeriana 6X HPUS occasional sleeplessness “HPUS” indicates that the active ingredients are in the official Homeopathic Pharmacopœia of the United States.
🧪 Inactive Ingredients ▾
Acacia Gum, Lactose.
🎯 Purpose ▾
Natural relief of occasional sleeplessness and restlessness due to stress.
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.