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Degree Advanced Fresh Energy Dry Spray 72H Antiperspirant Deodorant 17.6 g/100g Aerosol, Spray, 107 g — NDC 64942-1891-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Degree Advanced Fresh Energy Dry Spray 72H Antiperspirant Deodorant 17.6 g/100g Aerosol, Spray, 107 g — NDC 64942-1891-1 (Billing 64942-1891-01)

by Conopco, Inc. d/b/a Unilever · 107 g in 1 CAN

This is a package of 107 g of Degree Advanced Fresh Energy Dry Spray 72H Antiperspirant Deodorant 17.6 g/100g Aerosol, Spray from Conopco, Inc. d/b/a Unilever, marketed since Jul 2021 and currently FDA-listed. It is the main listing for this product, which comes in 2 package sizes.

NDC 64942-1891-01
🏷️ FDA NDC (as labeled) 64942-1891-1 billing pads the package segment with a zero
This package
Contains107 g Pack sizes2 compare ↓
Main listing for product 64942-1891 · Also comes in: 136 g 64942-1891-2
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 64942-1891-1 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
64942 labeler · 1891 product · 1 package
Package marketed since
Jul 19, 2021
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 6494218911 8
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 64942-1891-1
Product NDC 64942-1891
11-digit billing NDC 64942189101
UNII UCN889409V
Application # M019
SPL Set ID c3169744-7924-74ba-e053-2a95a90aa465
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2021-07-19
Route TOPICAL
Dosage form AEROSOL, SPRAY
Substance ALUMINUM SESQUICHLOROHYDRATE
Why two NDCs? The FDA registers this code as 64942-1891-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 64942-1891-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

Degree Advanced Fresh Energy is an over-the-counter antiperspirant deodorant spray marketed under FDA's monograph rules for this product category. The active ingredient aluminum sesquichlorohydrate is commonly used in antiperspirants to reduce underarm perspiration by forming a temporary plug in sweat ducts. This aerosol spray is applied topically to the skin and is typically used to help control moisture and odor throughout the day.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 136 g
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
64942-1891-01 You're viewing this Main listing 107 g in 1 CAN 2021-07-19 — Active
64942-1891-02 64942-1891-2 136 g in 1 CONTAINER 2021-07-19 — Active

You're viewing the smallest of 2 pack sizes for this product.

Pack size FAQ

What quantity is in this package?
This package contains 107 g — 107 g in 1 can.
How does this package differ from NDC 64942-1891-02?
Both are Degree Advanced Fresh Energy Dry Spray 72H Antiperspirant Deodorant 17.6 g/100g Aerosol, Spray — the drug itself is identical. This page's package is the 107 g one, while NDC 64942-1891-02 is the 136 g package.
What NDC number is used to bill for this package of Degree Advanced Fresh Energy Dry Spray 72H Antiperspirant Deodorant 17.6 g/100g Aerosol, Spray?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Degree 17.6 g/100gthis 64942-1891-01 Conopco, 107 g — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2021
On the market since
Jul 2021
📍
2026
Currently FDA-listed
5 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 0B1U8K2ME0
    A synthetic gas used as a propellant in pressurized aerosol inhalers. It helps deliver the active medication as a fine mist or spray into the lungs or airways.
  • UNII 6LV4FOR43R
    Butane is a colorless gas derived from petroleum. In medicines, it serves as a propellant in inhalers and aerosol sprays, helping deliver the active drug to the lungs or skin.
  • UNII 1P9D0Z171K
    BHT is a synthetic antioxidant that prevents fats and oils in medicines from breaking down and becoming rancid. It helps keep the product stable and effective during storage.
  • UNII M4I0D6VV5M
    Calcium chloride is a salt compound that acts as a firming agent and source of calcium ions in medications. It's used in formulations to help maintain tablet structure, improve texture, or serve as a buffering agent.
  • UNII 0THT5PCI0R
    A silicone-based liquid that helps distribute active ingredients evenly throughout topical products. It acts as a solvent and emollient, allowing medicines to spread smoothly on skin while improving texture and absorption.
  • UNII X687XDK09L
    A clay mineral processed to carry positive charges, used as a thickener and suspending agent in liquid medicines. It helps keep solid particles evenly distributed throughout the product.
  • UNII TE7660XO1C
    Glycine is an amino acid used in medicines as a buffer to help stabilize pH and improve taste. It may also serve as a filler or binder to give the product proper form and consistency.
  • UNII BXR49TP611
    Isobutane is a liquefied gas used as a propellant in aerosol inhalers and sprays. It helps push the medicine out of the container so you can breathe or spray it as directed.
  • UNII 7CVR7L4A2D
    A starch-derived carbohydrate produced by breaking down corn, potato, or tapioca starch. It functions as a filler and binder to give the medicine bulk and texture, and sometimes as a mild sweetener or texture enhancer in powders and tablets.
  • UNII R199TJT95T
    A synthetic liquid derived from propylene glycol and butyl alcohol. It functions as a solvent and humectant in medicines, helping dissolve active ingredients and maintain moisture in topical or oral formulations.
  • UNII T75W9911L6
    A flammable gas used as a propellant in aerosol formulations. It helps dispense the medicine as a fine mist or spray when you activate the inhaler or pump.
  • UNII 8D08K3S51E
    Propylene carbonate is a clear liquid solvent derived from propylene. It helps dissolve or suspend active ingredients in liquid medicines and can improve how well the product flows and mixes.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.

13 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesButane, Cyclopentasiloxane, Hydrofluorocarbon 152a, Isobutane, PPG-14 Butyl Ether, Glycine, Fragrance (Parfum), Disteardimonium Hectorite, Calcium Chloride, Propane, BHT, Propylene Carbonate, Sodium Starch Octenylsuccinate, Maltodextrin, Hydrolyzed Corn Starch Octenylsuccinate, Silica.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerConopco, Inc. d/b/a Unilever
FDA applicationM019 (OTC MONOGRAPH DRUG)
Labeler code64942
First marketedJul 2021
Product typeHuman Otc Drug
Portfolio181 products on file

More NDCs from Conopco, Inc. d/b/a Unilever labeler code 64942

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📋 Description 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 4 words ▾

Uses reduces underarm wetness

⏱️ Dosage and Administration 5 words ▾

Directions For underarms use only

⚠️ Warnings 112 words ▾

Warnings • FLAMMABLE. DO NOT USE NEAR HEAT, FLAME, OR WHILE SMOKING. CAN CAUSE SERIOUS INJURY OR DEATH • Keep away from face and mouth to avoid breathing in. • Avoid spraying in eyes.

Contents under pressure. Do not puncture or incinerate. Do not expose to heat or store at temperatures above 120°F/50°C or in enclosed places that could overheat • Do not use on broken skin.

Stop use if rash or irritation occurs. • Ask a doctor before using if you have kidney disease. • USE ONLY AS DIRECTED. INTENTIONAL MISUSE BY DELIBERATELY CONCENTRATING AND INHALING THE CONTENTS CAN BE HARMFUL OR FATAL. Help stop inhalation abuse.

For information visit www.inhalant.org

🧪 Active Ingredient 7 words ▾

Drug Facts Active ingredient Aluminum Sesquichlorohydrate (17.6%)

🧪 Inactive Ingredients 30 words ▾

Inactive ingredients Butane, Cyclopentasiloxane, Hydrofluorocarbon 152a, Isobutane, PPG-14 Butyl Ether, Glycine, Fragrance (Parfum), Disteardimonium Hectorite, Calcium Chloride, Propane, BHT, Propylene Carbonate, Sodium Starch Octenylsuccinate, Maltodextrin, Hydrolyzed Corn Starch Octenylsuccinate, Silica.

🎯 Purpose 2 words ▾

Purpose antiperspirant

📋 Description 14 words ▾

DEGREE ADVANCED FRESH ENERGY DRY SPRAY 72H ANTIPERSPIRANT DEODORANT - aluminum Sesquichlorohydrate aerosol, spray

📄 Keep Out of Reach of Children 7 words ▾

• KEEP OUT OF REACH OF CHILDREN

📄 Questions or Comments 4 words ▾

Questions? Call toll-free 1-866-334-7331

📄 Package Label / Principal Display Panel 7 words ▾

Degree Fresh Energy Dry Spray AP Deo

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Degree (this brand).

Top reported reactions

Application Site Erythema2
Application Site Irritation1
Application Site Pain1
Application Site Pruritus1
Burning Sensation1
Cyst1
Dermatitis Contact1

Reporter sex

4 reports
Male · 75%
Female · 25%
Reports over time (by year) — tap or hover for the count & year
2025 2026 2 1
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Conopco, Inc. d/b/a Unilever. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 136 g (64942-1891-02). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Conopco, Inc. d/b/a Unilever is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 64942-1890-01 · Conopco, 64942-1892-01 · Conopco, →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.