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bupropion 150 mg Tablet, Extended Release, 500-count — NDC 65841-0836-05 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

bupropion 150 mg Tablet, Extended Release, 500-count — NDC 65841-836-05 (Billing 65841-0836-05)

by Zydus Lifesciences Limited · 500 TABLET, EXTENDED RELEASE in 1 BOTTLE

This is a package of 500 tablets of bupropion 150 mg Tablet, Extended Release from Zydus Lifesciences Limited, marketed since Aug 2018 and currently FDA-listed. It is the main listing for this product, which comes in 4 package sizes.

NDC 65841-0836-05
🏷️ FDA NDC (as labeled) 65841-836-05 billing pads the product segment with a zero
This package
Contains500-count Pack sizes4 compare ↓
Also priced by: Part D plans $0.3192/unit — full pricing hub ↓
Main listing for product 65841-836 · Also comes in: 30 tablets 65841-836-06 90 tablets 65841-836-16 1000 tablets 65841-836-10
Rx only Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 65841-836-05
Product NDC 65841-836
11-digit billing NDC 65841083605
RxCUI 993541, 993557
UNII ZG7E5POY8O
Application # ANDA201567
SPL Set ID 78d34aad-9d4f-48c4-91eb-536e31c6b6c9
Established class (EPC) Aminoketone
Mechanism of action Dopamine Uptake Inhibitors; Norepinephrine Uptake Inhibitors
Physiologic effect Increased Dopamine Activity; Increased Norepinephrine Activity
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2018-08-02
Route ORAL
Dosage form TABLET, EXTENDED RELEASE
Substance BUPROPION HYDROCHLORIDE
TE code (Orange Book) AB3 · RLD · RS
Quick answers
  • RxCUI (RxNorm): 993541
Why two NDCs? The FDA registers this code as 65841-836-05 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 65841-0836-05. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Aminoketone class.

Pharmacologic class Aminoketone
Drug family (ATC) Centrally acting antiobesity products, Other antidepressants
How it works Norepinephrine Uptake Inhibitors, Dopamine Uptake Inhibitors
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📖 What it is MedlinePlus · NLM

Bupropion is used to treat depression. and seasonal affective disorder (SAD; episodes of depression that occur at the same time each year [usually in the fall and winter but rarely may occur in the spring or summer months]). Bupropion is also used to help people stop smoking. Bupropion is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain.

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Bupropion treats major depressive disorder. Some extended-release products, like Aplenzin and bupropion XL, can also prevent seasonal affective disorder, the depression that return...
  • Take it by mouth exactly as prescribed. XL tablets are taken once in the morning, with or without food, and must be swallowed whole. Your doctor will usually raise the dose gradual...
  • The most common ones are dry mouth, nausea, trouble sleeping, dizziness, headache, anxiety and tremor. Call your doctor right away if you have a seizure, new suicidal thoughts, sev...
  • It's best to limit or avoid alcohol. Rare neuropsychiatric events and lower alcohol tolerance have been reported. Never suddenly stop heavy drinking while on bupropion without talk...
📖 Read our full Bupropion guide →
1
Nutrient depletion considerations

Bupropion may be associated with lower levels of 1 nutrient — worth a chat with your pharmacist, not a cause for alarm.

An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · Q2 2026 $0.3192 $159.60 / 500 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
65841-0836-05 You're viewing this Main listing 500 TABLET, EXTENDED RELEASE in 1 BOTTLE 2018-08-02 — Active
65841-0836-06 65841-836-06 30 TABLET, EXTENDED RELEASE in 1 BOTTLE 2018-08-02 — Active
65841-0836-10 65841-836-10 1000 TABLET, EXTENDED RELEASE in 1 BOTTLE 2018-08-02 — Active
65841-0836-16 65841-836-16 90 TABLET, EXTENDED RELEASE in 1 BOTTLE 2018-08-02 — Active

You're viewing one of 4 pack sizes for this product.

Pack size FAQ

What quantity is in this package?
This is a 500-count package — 500 tablet, extended release in 1 bottle.
How does this package differ from NDC 65841-0836-06?
Both are bupropion 150 mg Tablet, Extended Release — the drug itself is identical. This page's package is the 500-count one, while NDC 65841-0836-06 is the 30 tablets package.
What NDC number is used to bill for this package of bupropion 150 mg Tablet, Extended Release?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Bupropion Hydrochloride 150 mg 68001-0519-03 BluePoint 500 tablets $0.077 AB3 Availability likely —
Bupropion Hydrochloride (XL) 150 mg 24979-0101-02 Upsher-Smith 500 tablets $0.078 — Discontinued —
Bupropion Hydrochloride XL 150 mg 00591-3331-05 Actavis 500 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride XL 150 mg 00904-7505-04 Major 1 tablet $0.078 AB3 Availability likely —
bupropion hydrochloride 150 mg 16571-0862-03 Rising 30 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride 150 mg 16729-0443-10 Accord 30 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride 150 mg 31722-0487-05 Camber 500 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride XL 150 mg 42806-0414-05 Epic 500 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride (XL) 150 mg 50228-0144-05 ScieGen 500 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride 150 mg 50268-0133-13 AvPAK 1 tablet $0.078 AB3 Availability likely —
Bupropion Hydrochloride 150 mg 60687-0782-01 American 1 tablet $0.078 AB3 Availability likely —
Bupropion Hydrochloride (Xl) 150 mg 62135-0875-30 Chartwell 30 tablets $0.078 AB3 Availability likely —
Bupropion hydrochloride 150 mg 68001-0613-03 BluePoint 500 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride XL 150 mg 68180-0319-02 Lupin 500 tablets $0.078 AB3 Availability likely —
bupropion 150 mg 68382-0353-05 Zydus 500 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride 150 mg 69097-0071-12 Cipla 500 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride XL 150 mg 69367-0288-05 Westminster 500 tablets $0.078 AB3 Discontinued —
Bupropion hydrochloride 150 mg 70010-0784-03 Granules 30 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride XL 150 mg 82009-0051-05 Quallent 500 tablets $0.078 AB3 Availability likely —
Bupropion Hydrochloride (XL) 150 mg 83301-0024-01 Mullan 30 tablets $0.078 AB3 Availability likely —
Bupropion hydrochloride 150 mg 63304-0723-05 Sun 500 tablets $0.079 — Discontinued —
Bupropion Hydrochloride XL 150 mg 42806-0348-05 Epic 500 tablets $0.079 AB3 Availability likely —
Bupropion Hydrochloride XL 150 mg 70436-0010-02 Slate 500 tablets $0.079 AB3 Availability likely —
Bupropion Hydrochloride (XL) 150 mg 43598-0655-05 Dr 500 tablets $0.108 AB3 FDA listed —
Bupropion hydrochloride (XL) 150 mg 00527-2415-32 Lannett 30 tablets $0.119 AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 69097-0875-02 CIPLA 30 tablets $0.119 — FDA listed —
Bupropion Hydrochloride 150 mg 00115-6811-02 Amneal 500 tablets — — FDA listed —
Wellbutrin Xl 150 mg 00187-0730-07 Bausch 7 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 00615-8504-05 NCS 15 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 47335-0954-13 Sun 500 tablets — — FDA listed —
Bupropion Hydrochloride XL 150 mg 50090-4049-00 A-S 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 50090-4747-00 A-S 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 50090-5163-00 A-S 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 50090-6789-00 A-S 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 50090-7109-00 A-S 90 tablets — — FDA listed —
Bupropion Hydrochloride (XL) 150 mg 50090-7110-00 A-S 90 tablets — — FDA listed —
Bupropion Hydrochloride XL 150 mg 50090-7112-00 A-S 90 tablets — AB3 Discontinued —
Bupropion Hydrochloride XL 150 mg 50090-7113-00 A-S 90 tablets — AB3 Discontinued —
Bupropion Hydrochloride 150 mg 50090-7711-00 A-S 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 50090-7712-00 A-S 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 51655-0098-26 Northwind 90 tablets — AB3 FDA listed —
Bupropion HCL ER (XL) 150 mg 61919-0558-60 Direct_Rx 60 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 63187-0713-30 Proficient 30 tablets — — FDA listed —
Bupropion Hydrochloride XL 150 mg 63187-0766-30 Proficient 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 63629-8474-01 Bryant 30 tablets — AB3 FDA listed —
bupropion 150 mgthis 65841-0836-05 Zydus 500 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 67046-0699-03 Coupler 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 68071-3559-09 NuCare 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 68071-3594-03 NuCare 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 68071-3927-03 NuCare 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 68071-3932-03 NuCare 30 tablets — AB3 FDA listed —
Bupropion hydrochloride 150 mg 68788-4010-01 Preferred 100 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 68788-7786-01 Preferred 100 tablets — AB3 FDA listed —
Bupropion hydrochloride (XL) 150 mg 69680-0157-30 Vitruvias 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 70518-2022-02 REMEDYREPACK 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 70518-2458-00 REMEDYREPACK 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 70518-3963-00 REMEDYREPACK 30 tablets — AB3 Discontinued —
Bupropion hydrochloride 150 mg 70518-4189-00 REMEDYREPACK 30 tablets — AB3 FDA listed —
Bupropion hydrochloride 150 mg 70518-4448-00 REMEDYREPACK 30 tablets — AB3 FDA listed —
bupropion hydrochloride 150 mg 70518-4674-00 REMEDYREPACK 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 71205-0291-30 Proficient 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 71205-0394-30 Proficient 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 71205-0504-30 Proficient 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 71205-0967-30 Proficient 30 tablets — — FDA listed —
Bupropion Hydrochloride 150 mg 71335-1044-01 Bryant 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 71335-2378-01 Bryant 30 tablets — AB3 FDA listed —
Bupropion hydrochloride 150 mg 71335-2469-01 Bryant 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 72162-1526-05 Bryant 500 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 72189-0134-30 DIRECT 30 tablets — AB3 FDA listed —
buPropion Hydrochloride XL 150 mg 72516-0035-03 Oryza 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 72789-0120-90 PD-Rx 90 tablets — — Discontinued —
Bupropion Hydrochloride 150 mg 72789-0301-90 PD-Rx 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 72789-0377-90 PD-Rx 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 76282-0480-05 Exelan 500 tablets — — FDA listed —
Bupropion Hydrochloride XL 150 mg 76420-0923-01 Asclemed 100 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 77771-0144-05 RADHA 500 tablets — AB3 FDA listed —
Bupropion hydrochloride 150 mg 80425-0300-01 Advanced 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride 150 mg 80425-0461-01 Advanced 30 tablets — AB3 FDA listed —
Bupropion Hydrochloride XL 150 mg 82804-0080-30 Proficient 30 tablets — AB3 FDA listed —
Bupropion hydrochloride 150 mg 82804-0296-90 Proficient 90 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 82868-0097-96 Northwind 180 tablets — AB3 FDA listed —
Bupropion Hydrochloride (XL) 150 mg 83008-0082-30 Quality 30 tablets — AB3 FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2018
On the market since
Aug 2018
📍
2026
Currently FDA-listed
8 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color Yellow
ShapeRound
Imprint353
Size8 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerZydus Lifesciences Limited
Application holderZYDUS PHARMACEUTICALS USA INC
FDA applicationANDA201567 (ANDA)
Labeler code65841
First marketedAug 2018
Product typeHuman Prescription Drug
Portfolio720 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
💬 Medication Guide 8 words ▾

Manufactured by: Cadila Healthcare Ltd. India.

SPL MEDGUIDE

📄 Package Label / Principal Display Panel 39 words ▾

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL NDC 65841-780-05 Bupropion Hydrochloride Extended-release Tablets USP (XL), 300 mg 500 Tablets Rx only NDC 65841-836-05 Bupropion Hydrochloride Extended-release Tablets USP (XL), 150 mg 500 Tablets Rx only Bupropion hydrochloride extended-release tablets, USP (XL) label

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Finished prescription product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data ✓ Available
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Zydus Lifesciences Limited. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 3 other package presentations of this same product, including 30 tablets (65841-0836-06), 90 tablets (65841-0836-16), 1000 tablets (65841-0836-10). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Zydus Lifesciences Limited is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.