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Eucerin Age Defense SPF 50 Sunscreen Avobenzone, Homosalate, Octisalate, Octocrylene 10 g/100g; 3 g/100g; 10 g/100g; 5 g/100g Lotion, 75 g — NDC 66800-5000-04 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Eucerin Age Defense SPF 50 Sunscreen Avobenzone, Homosalate, Octisalate, Octocrylene 10 g/100g; 3 g/100g; 10 g/100g; 5 g/100g Lotion, 75 g — NDC 66800-5000-4 (Billing 66800-5000-04)

by Beiersdort Inc · 75 g in 1 TUBE

This is a package of 75 g of Eucerin Age Defense SPF 50 Sunscreen Avobenzone, Homosalate, Octisalate, Octocrylene 10 g/100g; 3 g/100g; 10 g/100g; 5 g/100g Lotion from Beiersdort Inc, marketed since Nov 2021 and currently FDA-listed.

NDC 66800-5000-04
🏷️ FDA NDC (as labeled) 66800-5000-4 billing pads the package segment with a zero
This package
Contains75 g Pack sizes2 compare ↓
Product page 66800-5000-03 Also comes in: 10 g 66800-5000-3
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 66800-5000-4 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
66800 labeler · 5000 product · 4 package
Package marketed since
Nov 3, 2021
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 6680050004 2
FDA record last changed
Aug 27, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 66800-5000-4
Product NDC 66800-5000
11-digit billing NDC 66800500004
UNII 5A68WGF6WM, G63QQF2NOX, V06SV4M95S, 4X49Y0596W
Application # M020
SPL Set ID cd9d4f30-fb37-9935-e053-2995a90a9936
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2021-11-03
Route TOPICAL
Dosage form LOTION
Substance OCTOCRYLENE; AVOBENZONE; HOMOSALATE; OCTISALATE
Why two NDCs? The FDA registers this code as 66800-5000-4 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 66800-5000-04. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

Eucerin Age Defense SPF 50 is a topical lotion sunscreen marketed as an over-the-counter monograph product. It contains four active UV filter ingredients: avobenzone, homosalate, octisalate, and octocrylene, which are commonly used together in sunscreen formulations to absorb ultraviolet radiation and help protect skin from sun exposure. This product is formulated for application to the skin as a protective lotion.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 10 g
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
66800-5000-04 You're viewing this 75 g in 1 TUBE 2021-11-03 — Active
66800-5000-03 66800-5000-3 Main listing 10 g in 1 POUCH 2023-11-07 — Active

You're viewing the largest of 2 pack sizes for this product.

Pack size FAQ

What quantity is in this package?
This package contains 75 g — 75 g in 1 tube.
How does this package differ from NDC 66800-5000-03?
Both are Eucerin Age Defense SPF 50 Sunscreen Avobenzone, Homosalate, Octisalate, Octocrylene 10 g/100g; 3 g/100g; 10 g/100g; 5 g/100g Lotion — the drug itself is identical. This page's package is the 75 g one, while NDC 66800-5000-03 is the 10 g package.
What NDC number is used to bill for this package of Eucerin Age Defense SPF 50 Sunscreen Avobenzone, Homosalate, Octisalate, Octocrylene 10 g/100g; 3 g/100g; 10 g/100g; 5 g/100g Lotion?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Eucerin Age Defense SPF 50 Sunscreen 10 g/100g; 3 g/100g; 10 g/100g; 5 g/100gthis 66800-5000-04 Beiersdort 75 g — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2021
On the market since
Nov 2021
📍
2026
Currently FDA-listed
5 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color white
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
  • UNII A9EJ3J61HQ
    A synthetic liquid derived from benzoic acid and long-chain alcohols. It functions as a solvent and penetration enhancer in topical formulations, helping active ingredients dissolve and absorb into the skin.
  • UNII 75D21FL1PI
    A synthetic liquid derived from butylene glycol and fatty acids. It acts as an emollient and solvent to help dissolve or suspend active ingredients, improving texture and absorption in topical or oral formulations.
  • UNII 2EH13UN8D3
    A synthetic compound used as a solvent and penetration enhancer in topical formulations. It helps dissolve active ingredients and allows them to penetrate the skin more effectively.
  • UNII 2DMT128M1S
    A waxy solid derived from plant or animal sources. It acts as an emulsifier to blend oil and water components, and also thickens the medicine to give it the right texture and consistency.
  • UNII 936JST6JCN
    Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
  • UNII 6EKZ38572S
    Copernicia prunifera wax is a natural wax derived from the leaves of the carnauba palm tree. It's used in medicines as a coating agent to protect tablets and capsules, improve appearance, and control how quickly the medicine dissolves.
  • UNII F4K100DXP3
    Dibutyl adipate is a synthetic oily liquid derived from adipic acid. It serves as a plasticizer and solvent in medicines, helping softens coatings and improves flexibility so tablets and capsules don't crack or break.
  • UNII 3V5U97P248
    A synthetic organic compound used as a UV filter and stabilizer in medications. It helps protect the drug from light degradation and may improve shelf life in formulations exposed to sunlight.
  • UNII G3232Z5S2O
    A synthetic emollient and emulsifier derived from plant oils and glycerin. It helps blend oil and water components together and gives the product a smooth texture in topical formulations.
  • UNII 92RU3N3Y1O
    Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
  • UNII 45ASM2L11M
    A synthetic ingredient derived from glutamic acid and stearic acid. It acts as an emulsifier and surfactant, helping oils and water mix smoothly in the medication formulation.
  • UNII 9G1OE216XY
    Docosanol is a waxy, fatty alcohol derived from plant sources. It acts as an emollient and thickener in topical medicines, helping to soften the skin and improve product texture and stability.
  • UNII 7FLD91C86K
    Edetate disodium is a chemical compound that binds and removes certain metal ions. In medicines, it acts as a preservative and stabilizer by preventing metals like calcium from interfering with the product's shelf life and consistency.
  • UNII P540XA09DR
    Enoxolone is a naturally derived compound from licorice root that acts as a skin-soothing and anti-inflammatory agent. In medicines, it helps reduce irritation and supports the healing of mucous membranes or damaged skin.
  • UNII 7Z8S9VYZ4B
    Ethylcellulose is a plant-derived thickener and film-former made by chemically modifying cellulose. It's used as a binder to hold tablet ingredients together, a coating to control how quickly medicine is released, or a thickener in liquid formulations.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 8KVN59D5FL
    A naturally occurring amino acid compound that combines glycine and carnitine. It acts as a filler and stabilizer to help maintain the medicine's structure and shelf life.
  • UNII 1MV1Z7MKVQ
    A plant extract from licorice root used as a natural sweetener and flavoring agent in medicines. It may also help soothe throat irritation and improve taste.
  • UNII YSE9PPT4TH
    Hyaluronate sodium is a natural carbohydrate that holds moisture. It's used in medicines as a lubricant, thickener, and moisture-retaining agent to improve texture and delivery of the active ingredient.
  • UNII G1L3HT4CMH
    A synthetic compound used in medicines as a preservative and antimicrobial agent. It helps prevent bacterial and fungal growth, extending the product's shelf life.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII 4T2L7QI313
    A waxy, plant-derived thickener made from glycerol and behenic acid. It's used as an emulsifier and stabilizer to help blend oil and water-based ingredients together and maintain texture in creams and lotions.
  • UNII Z35I17EQOP
    A waxy substance made from glycerin and stearic acid that helps stabilize and thicken cosmetic and pharmaceutical formulations. It works as an emulsifier to blend oil and water-based ingredients together.
  • UNII ETY9Q81E2T
    A synthetic emulsifier made from glycerin and stearic acid. It helps blend oil and water-based ingredients together so the medicine mixes evenly and stays stable.
  • UNII EU2PSP0G0W
    Silica dimethyl silylate is a silicon-based powder that acts as a glidant and anti-caking agent. It reduces friction between particles and helps powders flow smoothly during manufacturing and tablet compression.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
  • UNII 836SJG51DR
    Sodium ascorbyl phosphate is a derivative of vitamin C that acts as an antioxidant and preservative in medications. It helps protect the drug's active ingredients from degradation caused by air and light exposure.
  • UNII R0ZB2556P8
    Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII TTV12P4NEE
    Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.

32 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesWater, Alcohol Denat., Butyloctyl Salicylate, Silica, C12-15 Alkyl Benzoate, Polyglyceryl-6 Stearate, Sodium Stearoyl Glutamate, Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate, Behenyl Alcohol, Butylene Glycol Dicaprylate/Dicaprate, Cetearyl Alcohol, Copernicia Cerifera (Carnauba) Wax, Dibutyl Adipate, Sodium Hyaluronate, Glycyrrhiza Inflata Root Extract, Glycyrrhetinic Acid, Tocopherol, Dimethicone, Silica Dimethyl Silylate, Diethylhexyl Syringylidenemalonate, Ethylcellulose, Glyceryl Behenate, L-Carnitine, Polyglyceryl-6 Octastearate, Phenoxyethanol, Glycerin, Xanthan Gum, Ethylhexylglycerin, Disodium EDTA, Hydroxyacetophenone, Polyglyceryl-6 Behenate, Cetyl Alcohol, Sodium Ascorbyl Phosphate

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerBeiersdort Inc
FDA applicationM020 (OTC MONOGRAPH DRUG)
Labeler code66800
First marketedNov 2021
Product typeHuman Otc Drug
Portfolio5 products on file

More NDCs from Beiersdort Inc labeler code 66800

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 31 words ▾

Uses ■ helps prevent sunburn ■ if used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun

⏱️ Dosage and Administration 98 words ▾

Directions ■ apply liberally 15 minutes before sun exposure ■ reapply at least every 2 hours ■ use a water resistant sunscreen if swimming or sweating ■ Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: ■ limit time in the sun, especially from 10 a.m. – 2 p.m. ■ wear long-sleeve shirts, pants, hats, and sunglasses ■ children under 6 months: Ask a doctor

⚠️ Warnings 5 words ▾

Warnings For external use only

🧪 Active Ingredient 6 words ▾

Active ingredients Avobenzone, Homosalate, Octisalate, Octocrylene

🧪 Inactive Ingredients 69 words ▾

Inactive ingredients Water, Alcohol Denat., Butyloctyl Salicylate, Silica, C12-15 Alkyl Benzoate, Polyglyceryl-6 Stearate, Sodium Stearoyl Glutamate, Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate, Behenyl Alcohol, Butylene Glycol Dicaprylate/Dicaprate, Cetearyl Alcohol, Copernicia Cerifera (Carnauba) Wax, Dibutyl Adipate, Sodium Hyaluronate, Glycyrrhiza Inflata Root Extract, Glycyrrhetinic Acid, Tocopherol, Dimethicone, Silica Dimethyl Silylate, Diethylhexyl Syringylidenemalonate, Ethylcellulose, Glyceryl Behenate, L-Carnitine, Polyglyceryl-6 Octastearate, Phenoxyethanol, Glycerin, Xanthan Gum, Ethylhexylglycerin, Disodium EDTA, Hydroxyacetophenone, Polyglyceryl-6 Behenate, Cetyl Alcohol, Sodium Ascorbyl Phosphate

🎯 Purpose 2 words ▾

Purpose Sunscreen

📄 Do Not Use 8 words ▾

Do not use on damaged or broken skin

📄 When Using This Product 13 words ▾

When using this product keep out of eyes. Rinse with water to remove.

📄 Stop Use and Ask a Doctor If 9 words ▾

Stop use and ask a doctor if rash occurs

📄 Keep Out of Reach of Children 21 words ▾

Keep out of reach of children. If porduct is swallowed, get medical help or contact a Poison Control Center right away.

📄 Questions or Comments 2 words ▾

Questions? 1-800-227-4703

📄 Package Label / Principal Display Panel 46 words ▾

Eucerin ® Age Defense +Hyaluronic Acid Lightweight Sunscreen Lotion For Face 50 Broad Spectrum SPF 50 Helps Reduce The Signs of Aging* Hypoallergenic | Fragrance Free No Oxybenzone & Octinoxate 5 AOX Shield Antioxidant Defense Developed with Dermatologists

2.5 FL OZ (75 mL) Eucerin Age Defense

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Beiersdort Inc. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 10 g (66800-5000-03). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Beiersdort Inc is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 66800-4839-06 · Beiersdorf 66800-5049-05 · Beiersdorf →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.