Allopurinol 300 mg Tablet, 30-count — NDC 67046-0681-3 (Billing 67046-0681-03)
This is a package of 30 tablets of Allopurinol 300 mg Tablet from Coupler LLC, marketed since Feb 2018 and currently FDA-listed. It is this product's only package size.
NDC database record
One package, one record: these facts belong to NDC 67046-0681-3 alone.
- Record
- FDA NDC Directory package listing · Human prescription drug
- Code segments
- 67046 labeler · 0681 product · 3 package
- Package marketed since
- Feb 23, 2018
- Sample package
- No — commercial package
- Listing certified through
- Dec 31, 2027
- Barcode (UPC)
- 0303780181052
- FDA record last changed
- Jul 24, 2026
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
- RxCUI (RxNorm): 197320
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 1, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 1, 2026
RxNorm drug class
This medicine belongs to the Xanthine Oxidase Inhibitor class.
Where does this data come from?
- RxClass (NLM) · catalog refreshed Oct 1, 2026
Clinical
- Allopurinol lowers uric acid. The tablets are used for gout, for high uric acid caused by cancer treatment, and for recurrent calcium oxalate kidney stones in certain adults. The I...
- No. Flares can happen early as uric acid shifts, and it can take months to settle. Your doctor will likely suggest colchicine or an anti-inflammatory to help prevent them. Keep tak...
- I got a gout flare after starting it. Should I stop?
- Nausea, diarrhea and mild changes in liver tests are the most common. A skin rash is the one to take seriously. Stop the medicine and get medical help right away if a rash or aller...
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Allopurinol — tap one for details:
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 1, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · Q2 2026 | $0.1123 | $3.37 / 30 tablets |
Where does this data come from?
- CMS NADAC weekly file
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · refreshed Oct 3, 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Marketing end | Status |
|---|---|---|---|---|
| 67046-0681-03 You're viewing this Main listing | 30 TABLET in 1 BLISTER PACK | 2018-02-23 | — | Active |
Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Allopurinol 300 mg 00378-0181-01 | Mylan | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 00591-5544-01 | Actavis | 100 tablets | $0.052 | — | Availability likely | — |
| Allopurinol 300 mg 00603-2116-21 | Par | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 00904-6572-61 | Major | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 16571-0885-09 | Rising | 90 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 16714-0577-01 | NorthStar | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 23155-0694-01 | Heritage | 100 tablets | $0.052 | AB | Discontinued | — |
| Allopurinol 300 mg 29300-0350-01 | Unichem | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 31722-0253-01 | Camber | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 51079-0206-20 | Mylan | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 53489-0157-01 | Sun | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 55111-0730-01 | Dr. | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 59651-0286-01 | Aurobindo | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 60687-0688-01 | American | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 62135-0517-31 | Chartwell | 300 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 69315-0292-01 | Leading | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 71921-0242-01 | Florida | 100 tablets | $0.052 | AB | Availability likely | — |
| Allopurinol 300 mg 16729-0135-01 | Accord | 100 tablets | $0.075 | AB | FDA listed | — |
| Allopurinol 300 mg 00615-8517-05 | NCS | 15 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 14445-0171-00 | Indoco | 1000 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 43063-0934-01 | PD-Rx | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 43063-0976-30 | PD-Rx | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 43353-0186-60 | Aphena | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 48433-0003-20 | Safecor | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 50090-4663-00 | A-S | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 50090-6882-00 | A-S | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 50090-6968-00 | A-S | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 50090-7351-00 | A-S | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 50090-7353-00 | A-S | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 50090-7792-00 | A-S | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 51655-0782-26 | Northwind | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 51655-0968-26 | Northwind | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 55154-5454-00 | Cardinal | 10 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 55154-7981-00 | Cardinal | 10 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 60760-0722-90 | ST. | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 60760-0989-90 | St. | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 63187-0240-30 | Proficient | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 63629-1781-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 63629-2112-01 | Bryant | 500 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 63629-2113-01 | Bryant | 1000 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mgthis 67046-0681-03 | Coupler | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 67046-1514-03 | Coupler | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 67046-1639-03 | Coupler | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 67046-1658-03 | Coupler | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 67544-0313-45 | Aphena | 45 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 68071-3605-09 | NuCare | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 68071-3672-09 | NuCare | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 68788-6323-01 | Preferred | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 68788-8364-01 | Preferred | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 68788-8424-01 | Preferred | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 68788-8713-01 | Preferred | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 68788-8865-01 | Preferred | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 70518-3704-00 | REMEDYREPACK | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 70518-4286-00 | REMEDYREPACK | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 70518-4404-00 | REMEDYREPACK | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 70518-4556-00 | REMEDYREPACK | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 70710-1210-00 | Zydus | 1000 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 70771-1127-00 | Zydus | 1000 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71205-0049-30 | Proficient | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71205-0377-30 | Proficient | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71335-0112-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71335-2332-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71335-3082-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71335-9634-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71335-9676-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71610-0064-45 | Aphena | 45 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71610-0253-60 | Aphena | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71610-0681-45 | Aphena | 45 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 72162-1150-00 | Bryant | 1000 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 72189-0417-90 | Direct_Rx | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 72189-0647-90 | Direct_Rx | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 72865-0304-01 | XLCare | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 80425-0206-01 | Advanced | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 80425-0383-01 | Advanced | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 80425-0518-01 | Advanced | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 82638-0113-02 | Harman | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 82868-0099-30 | Northwind | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 70518-4693-00 | REMEDYREPACK | 100 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 71335-3154-01 | Bryant | 30 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 55154-0282-00 | Cardinal | 10 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 53401-0025-60 | Aphena | 90 tablets | — | AB | FDA listed | — |
| Allopurinol 300 mg 72789-0593-90 | PD-Rx | 90 tablets | — | AB | FDA listed | — |
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA Orange Book · refreshed Oct 3, 2026
- CMS NADAC weekly file
Availability & generic status
This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.
Where does this data come from?
- FDA Orange Book · refreshed Oct 3, 2026
What it looks like
Where does this data come from?
- FDA label on DailyMed · label index refreshed Oct 1, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Where does this data come from?
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.- FDA label on DailyMed · label index refreshed Oct 1, 2026
- FDA openFDA NDC Directory · synced Oct 1, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
More NDCs from Coupler LLC labeler code 67046
- Quetiapine fumarate 300 mg Tablet NDC 67046-0638-3
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- clonidine hydrochloride .3 mg Tablet NDC 67046-0646-3
- Atenolol 25 mg Tablet NDC 67046-0663-3
- Prazosin Hydrochloride 1 mg Capsule NDC 67046-0680-3
- Amitriptyline Hydrochloride 25 mg Tablet, Film Coated NDC 67046-0689-3
- Olanzapine 5 mg Tablet, Film Coated NDC 67046-0690-3
- Bupropion Hydrochloride XL 150 mg Tablet, Extended Release NDC 67046-0699-3
- Losartan Potassium 100 mg Tablet, Film Coated NDC 67046-0702-3
- Carbamazepine 200 mg Tablet NDC 67046-0707-3
- Hydroxyzine hydrochloride 25 mg Tablet NDC 67046-0713-3
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- Drugs@FDA
Full prescribing information FDA SPL
💬 Patient Medication Information ▾
Mylan Pharmaceuticals Inc. Allopurinol allopurinol ALLOPURINOL ALLOPURINOL SILICON DIOXIDE MAGNESIUM STEARATE CELLULOSE, MICROCRYSTALLINE STARCH, CORN SODIUM LAURYL SULFATE SODIUM STARCH GLYCOLATE TYPE A POTATO M;31 Allopurinol allopurinol ALLOPURINOL ALLOPURINOL SILICON DIOXIDE MAGNESIUM STEARATE CELLULOSE, MICROCRYSTALLINE STARCH, CORN SODIUM LAURYL SULFATE SODIUM STARCH GLYCOLATE TYPE A POTATO M;71 DESCRIPTION Allopurinol has the following structural formula: Allopurinol is known chemically as 1,5-dihydro-4H-pyrazolo [3,4-d] pyrimidin-4-one.
It is a xanthine oxidase inhibitor which is administered orally. Its solubility in water at 37°C is 80.0 mg/dL and is greater in an alkaline solution. Each tablet for oral administration contains either 100 mg or 300 mg of allopurinol, USP and the following inactive ingredients: colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium lauryl sulfate and sodium starch glycolate.
Allopurinol Structural Formula CLINICAL PHARMACOLOGY Allopurinol acts on purine catabolism, without disrupting the biosynthesis of purines. It reduces the production of uric acid by inhibiting the biochemical reactions immediately preceding its formation. Allopurinol is a structural analogue of the natural purine base, hypoxanthine.
It is an inhibitor of xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine to xanthine and of xanthine to uric acid, the end product of purine metabolism in man. Allopurinol is metabolized to the corresponding xanthine analogue, oxipurinol (alloxanthine), which also is an inhibitor of xanthine oxidase. It has been shown that reutilization of both hypoxanthine and xanthine for nucleotide and nucleic acid synthesis is markedly enhanced when their oxidations are inhibited by allopurinol and oxipurinol.
This reutilization does not disrupt normal nucleic acid anabolism, however, because feedback inhibition is an integral part of purine biosynthesis. As a result of xanthine oxidase inhibition, the serum concentration of hypoxanthine plus xanthine in patients receiving allopurinol for treatment of hyperuricemia is usually in the range of 0.3 mg to 0.4 mg/dL compared to a normal level of approximately 0.15 mg/dL. A maximum of 0.9 mg/dL of these oxypurines has been reported when the serum urate was lowered to less than 2 mg/dL by high doses of allopurinol.
These values are far below the saturation levels at which point their precipitation would be expected to occur (above 7 mg/dL). The renal clearance of hypoxanthine and xanthine is at least 10 times greater than that of uric acid. The increased xanthine and hypoxanthine in the urine have not been accompanied by problems of nephrolithiasis.
Xanthine crystalluria has been reported in only three patients. Two of the patients had Lesch-Nyhan syndrome, which is characterized by excessive uric acid production combined with a deficiency of the enzyme, hypoxanthine guanine phosphoribosyltransferase (HGPRTase). This enzyme is required for the conversion of hypoxanthine, xanthine, and guanine to their respective nucleotides.
The third patient had lymphosarcoma and produced an extremely large amount of uric acid because of rapid cell lysis during chemotherapy. Allopurinol is approximately 90% absorbed from the gastrointestinal tract. Peak plasma levels generally occur at 1.5 hours and 4.5 hours for allopurinol and oxipurinol, respectively, after a single oral dose of 300 mg allopurinol, maximum plasma levels of about 3 mcg/mL of allopurinol and 6.5 mcg/mL of oxipurinol are produced.
Approximately 20% of ingested allopurinol is excreted in the feces. Because of its rapid oxidation to oxipurinol and a renal clearance rate approximately that of glomerular filtration rate, allopurinol has a plasma half-life of about 1 to 2 hours. Oxipurinol, however, has a longer plasma half-life (approximately 15 hours) and therefore effective xanthine oxidase inhibition is maintained over a 24 hour per…
Medicare Part D spend CMS · PART D · 2026 (Q1)
About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | — Not published for this NDC No photo available yet for this listing. |
| Inactive ingredients (structured) | — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available. |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | ✓ Available |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |