Home › NDC Lookup › 69396-0071-01
Dual Action Cream NeomycinSulfate,PolymyxinBSulfate,PramoxineHCL 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g Cream, 1 tube — NDC 69396-0071-01 package photo

Dual Action Cream NeomycinSulfate,PolymyxinBSulfate,PramoxineHCL 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g Cream, 1 tube

by Trifecta Pharmaceutical USA LLC · 1 TUBE in 1 BOX (69396-071-01) / 28.4 g in 1 TUBE
NDC 69396-0071-01
🏷️ FDA NDC (as labeled) 69396-071-01 billing pads the product segment with a zero
This package
Contains1 tube Pack sizes3 compare ↓
Also comes in: 2 tubes 69396-0071-22 4 tubes 69396-0071-44
OTC On market Non-controlled
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 69396-071-01
Product NDC 69396-071
11-digit billing NDC 69396007101
RxCUI 1359360
UNII 057Y626693, 88AYB867L5, 19371312D4
UPC 0860004834489
Application # M004
SPL Set ID b84015ae-9c76-b1d7-e053-2a95a90a2cc8
Established class (EPC) Aminoglycoside Antibacterial; Polymyxin-class Antibacterial
Chemical class Aminoglycosides; Polymyxins
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2021-01-06
Route TOPICAL
Dosage form CREAM
Substance NEOMYCIN SULFATE; PRAMOXINE HYDROCHLORIDE; POLYMYXIN B SULFATE
Why two NDCs? The FDA registers this code as 69396-071-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 69396-0071-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Local anesthetics class.

Drug family (ATC) Local anesthetics, Anesthetics for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerTrifecta Pharmaceutical USA LLC
FDA applicationM004 (OTC MONOGRAPH DRUG)
Labeler code69396
First marketedJan 2021
Product typeHuman Otc Drug
Portfolio7 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is a topical antibiotic cream sold as an over-the-counter monograph product. It contains neomycin sulfate and polymyxin B sulfate, which are antibiotics typically used to help prevent or treat minor bacterial skin infections. The cream also contains pramoxine hydrochloride, a local anesthetic commonly used to reduce itching and pain on the skin. This combination product is designed for application directly to affected skin areas.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 2DMT128M1S
    A waxy solid derived from plant or animal sources. It acts as an emulsifier to blend oil and water components, and also thickens the medicine to give it the right texture and consistency.
  • UNII 14255EXE39
    Ethylparaben is a preservative, a chemical that stops bacteria and mold from growing in the medicine. It keeps the product safe and effective throughout its shelf life.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 230OU9XXE4
    A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
  • UNII N72LMW566G
    A synthetic cleansing agent derived from lauryl alcohol and ethylene oxide. It helps dissolve and mix oil and water-based ingredients in liquid medicines, acting as an emulsifier and solubilizer.
  • UNII N6K5787QVP
    Light mineral oil is a clear, odorless liquid derived from petroleum. In medicines, it acts as a lubricant and emollient to help the product spread smoothly and improve texture.
  • UNII 4T6H12BN9U
    Petrolatum is a purified mineral oil-based jelly derived from petroleum. In medicines, it acts as an emollient, lubricant, and moisture barrier to soften skin, reduce friction, and help prevent water loss from formulations.
  • UNII 368GB5141J
    A detergent and foaming agent derived from coconut or palm oil. In medications, it helps break down and mix oil and water-based ingredients, aids in tablet disintegration, and improves how the drug dissolves and spreads in the mouth or digestive system.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

9 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesCetostearyl alcohol, Ethylparaben, Glycerin, Glyceryl monosterate, Light Mineral Oil, Petrolatum, Polyoxyethylene Lauryl Ether, Purified Water, Sodium Lauryl Sulfate.

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 2 tubes 4 tubes
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Good Neighbor Pharmacy Antibiotic and Pain Relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 46122-0244-03 Amerisource 1 tube $0.097 — Availability likely —
Antibiotic and Pain Relief 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g 70677-1218-01 STRATEGIC 1 tube $0.189 — Availability likely —
Walgreens Kids Multi-Antibiotic with Pain Relief Cream 10000 [USP'U]/g; 3.5 mg/g; 10 mg/g 00363-2122-14 Walgreens 1 tube — — FDA listed —
Walgreens Multi-Antibiotic with Pain Relief Cream 10000 [USP'U]/g; 3.5 mg/g; 10 mg/g 00363-2123-14 Walgreens 1 tube — — FDA listed —
Antibiotic Plus Pain Relief 3.5 mg/g; 10000 [iU]/g; 10 mg/g 11673-0393-01 TARGET 1 tube — — FDA listed —
Antibiotic and Pain Relief 10000 [USP'U]/g; 3.5 mg/g; 10 mg/g 11673-0770-14 Target 1 tube — — FDA listed —
Signature Care First Aid Antibiotic 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 21130-0559-58 Safeway 1 tube — — FDA listed —
antibiotic plus pain relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 30142-0790-58 Kroger 1 tube — — FDA listed —
TopCare Antibiotic Plus Pain Relief 3.5 mg/g; 10000 [iU]/g; 10 mg/g 36800-0381-01 Topco 1 tube — — FDA listed —
Topcare Antibiotic 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g 36800-0976-58 Topco 1 tube — — FDA listed —
antibiotic 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 37808-0005-58 H 1 tube — — FDA listed —
Publix antibiotic plus Pain Relief 3.5 mg/g; 10000 [iU]/g; 10 mg/g 41415-0076-75 Publix 1 tube — — FDA listed —
Equate Antibiotic Plus Pain Relief 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g 49035-0847-05 WalMart 1 tube — — FDA listed —
DG Health Antibiotic 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 55910-0061-64 Dolgencorp 1 tube — — FDA listed —
Family Care Antibiotic Pain Relief 0.33oz 10 mg/g; 10000 [USP'U]/g; 3.5 mg/g 65923-0578-33 United 1 tube — — FDA listed —
Premier Value Max Strength Antibiotic plus pain relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 68016-0296-05 Pharmacy 1 tube — — FDA listed —
Dual Action Cream 3.5 mg/g; 10 mg/g; 10000 [USP'U]/gthis 69396-0071-01 Trifecta 1 tube — — FDA listed —
Antibiotic and Pain Relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 69842-0754-58 CVS 1 tube — — FDA listed —
Neosporin Kids Plus Pain Relief 3.5 mg/g; 10000 [iU]/g; 10 mg/g 69968-0054-01 Kenvue 1 tube — — FDA listed —
Neosporin Plus Pain Relief First Aid Antibiotic/Pain Relieving 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g 69968-0055-01 Kenvue 1 tube — — FDA listed —
first aid antibiotic and pain relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 79481-0809-00 Meijer, 1 tube — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2021
On the market since
Jan 2021
📍
2026
Currently FDA-listed
5 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
69396-0071-01 You're viewing this 1 TUBE in 1 BOX (69396-071-01) / 28.4 g in 1 TUBE 2021-01-22 Active
69396-0071-22 2 TUBE in 1 BOX (69396-071-22) / 28.4 g in 1 TUBE 2025-08-23 Active
69396-0071-44 4 TUBE in 1 BOX (69396-071-44) / 28.4 g in 1 TUBE 2024-12-02 Active

Pack size FAQ

What quantity is in NDC 69396-0071-01?
NDC 69396-0071-01 contains 1 tube — 1 tube in 1 box / 28.4 g in 1 tube.
What is the difference between NDC 69396-0071-01 and NDC 69396-0071-22?
Both are Dual Action Cream NeomycinSulfate,PolymyxinBSulfate,PramoxineHCL 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g Cream — the drug itself is identical. NDC 69396-0071-01 is the 1 tube package, while NDC 69396-0071-22 is the 2 tubes package.
What NDC number is used to bill for this package of Dual Action Cream NeomycinSulfate,PolymyxinBSulfate,PramoxineHCL 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g Cream?
Bill NDC 69396-0071-01 — the 11-digit billing format is 69396007101. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 69396-071-01, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 69396-0071-01, written without dashes as 69396007101. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 69396-0071-01, the first segment (69396) is the labeler code FDA assigned to Trifecta Pharmaceutical USA LLC; the middle segment (0071) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Trifecta Pharmaceutical USA LLC. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 2 tubes (69396-0071-22), 4 tubes (69396-0071-44). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Trifecta Pharmaceutical USA LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 21 words ▾

Uses First Aid to help prevent infection iand for temporary relief of pain or discomfort in minor cuts, scrapes and burns.

⏱️ Dosage and Administration 58 words ▾

Directions Adults and children 2 years of age and older Clean the affected area Apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily May be covered with a sterile bandage Children under 2 years of age: ask a doctor

⚠️ Warnings 26 words ▾

Warnings For external use only. Do not use: If you are allergic to any of the ingredients in the eyes over large areas of the body

📦 Storage and Handling 10 words ▾

Other Information Store at 20° to 25°C (68° to 77°F)

🧪 Active Ingredient 15 words ▾

Active Ingredient Neomycin 3.5mg

Active Ingredient Polymyxin B 10,000 Units

Active Ingredient Pramoxine HCL 10mg

🧪 Inactive Ingredients 20 words ▾

Inactive Ingredient: Cetostearyl alcohol, Ethylparaben, Glycerin, Glyceryl monosterate, Light Mineral Oil, Petrolatum, Polyoxyethylene Lauryl Ether, Purified Water, Sodium Lauryl Sulfate.

🎯 Purpose 11 words ▾

Purpose First Aid Antibiotic

Purpose First Aid Antibiotic

Purpose External Analgesic

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 69396-0070-01 · Trifecta 69396-0072-01 · Trifecta →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.