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Antibiotic and Pain Relief Neomycin Sulfate, Polymyxin B Sulfate, and Pramoxine Hydrochloride 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g Cream, 1 tube — NDC 70677-1218-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Antibiotic and Pain Relief Neomycin Sulfate, Polymyxin B Sulfate, and Pramoxine Hydrochloride 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g Cream, 1 tube — NDC 70677-1218-1 (Billing 70677-1218-01)

by STRATEGIC SOURCING SERVICES LLC · 1 TUBE in 1 CARTON / 14.2 g in 1 TUBE

This is a package of 1 tube of Antibiotic and Pain Relief Neomycin Sulfate, Polymyxin B Sulfate, and Pramoxine Hydrochloride 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g Cream from STRATEGIC SOURCING SERVICES LLC, marketed since Jan 2024 and currently FDA-listed, this package's marketing is listed to end Mar 2027; retail pharmacies pay about $0.1887 per g (NADAC). It is this product's only package size.

NDC 70677-1218-01
🏷️ FDA NDC (as labeled) 70677-1218-1 billing pads the package segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 70677-1218-1
Product NDC 70677-1218
11-digit billing NDC 70677121801
NCPDP billing unit GM — per gram (weight)
RxCUI 1359360
UNII 057Y626693, 19371312D4, 88AYB867L5
Application # M017
SPL Set ID f7aa9330-c47c-4d2f-b784-11b831d919d6
Established class (EPC) Aminoglycoside Antibacterial; Polymyxin-class Antibacterial
Chemical class Aminoglycosides; Polymyxins
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2024-01-24
Marketing end 2027-03-31
Route TOPICAL
Dosage form CREAM
Substance NEOMYCIN SULFATE; POLYMYXIN B SULFATE; PRAMOXINE HYDROCHLORIDE

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GPI-14 90109803353720
GCN Seq No 052110
GCN 19626
HICL code 025197
Ingredient (HICL) Neomycin/Polymyxin B/Pramoxine
HIC1 code Q
Therapeutic class — broad (HIC1) Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code Q5
Therapeutic class — intermediate (HIC2) Agents Acting Principally On The Skin
HIC3 code Q5W
Therapeutic class — specific (HIC3) Topical Antibiotics
AHFS code 08:12.02.00
AHFS class Aminoglycoside Antibiotics
FDB label name FT ANTIBIOTIC-PAIN RELIEF CRM
FDB brand name Antibiotic Plus Pain Relief
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 052110
  • GCN: 19626
  • GPI-14 (Medi-Span): 90109803353720
  • HICL (First Databank): 025197
  • AHFS class code: 08:12.02.00
  • RxCUI (RxNorm): 1359360
Why two NDCs? The FDA registers this code as 70677-1218-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 70677-1218-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Local anesthetics class.

Drug family (ATC) Local anesthetics, Anesthetics for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

Label name FT ANTIBIOTIC-PAIN RELIEF CRM Ingredient Neomycin/Polymyxin B/Pramoxine
🧪 What is this product?

This is an over-the-counter topical cream sold under FDA's OTC monograph rules for antibiotic and pain relief products. It contains neomycin sulfate and polymyxin B sulfate, which are antibiotics typically used to help prevent bacterial infection in minor cuts and scrapes, along with pramoxine hydrochloride, a local anesthetic commonly used to numb minor pain and itching. The cream is applied directly to the skin.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly $0.189 $2.68 / 14.2 g
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per g) — tap or hover for the price & month
Dec 2025 Jan 2026 Feb 2026 $0.189 $0.189
Flat over the last 3 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
70677-1218-01 You're viewing this Main listing 1 TUBE in 1 CARTON / 14.2 g in 1 TUBE 2024-01-24 Mar 31, 2027 Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Good Neighbor Pharmacy Antibiotic and Pain Relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 46122-0244-03 Amerisource 1 tube $0.097 — Availability likely save 49%
Antibiotic and Pain Relief 3.5 mg/g; 10000 [USP'U]/g; 10 mg/gthis 70677-1218-01 STRATEGIC 1 tube $0.189 — Availability likely —
Walgreens Kids Multi-Antibiotic with Pain Relief Cream 10000 [USP'U]/g; 3.5 mg/g; 10 mg/g 00363-2122-14 Walgreens 1 tube — — FDA listed —
Walgreens Multi-Antibiotic with Pain Relief Cream 10000 [USP'U]/g; 3.5 mg/g; 10 mg/g 00363-2123-14 Walgreens 1 tube — — FDA listed —
Antibiotic Plus Pain Relief 3.5 mg/g; 10000 [iU]/g; 10 mg/g 11673-0393-01 TARGET 1 tube — — FDA listed —
Antibiotic and Pain Relief 10000 [USP'U]/g; 3.5 mg/g; 10 mg/g 11673-0770-14 Target 1 tube — — FDA listed —
Signature Care First Aid Antibiotic 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 21130-0559-58 Safeway 1 tube — — FDA listed —
antibiotic plus pain relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 30142-0790-58 Kroger 1 tube — — FDA listed —
TopCare Antibiotic Plus Pain Relief 3.5 mg/g; 10000 [iU]/g; 10 mg/g 36800-0381-01 Topco 1 tube — — FDA listed —
Topcare Antibiotic 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g 36800-0976-58 Topco 1 tube — — FDA listed —
antibiotic 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 37808-0005-58 H 1 tube — — FDA listed —
Publix antibiotic plus Pain Relief 3.5 mg/g; 10000 [iU]/g; 10 mg/g 41415-0076-75 Publix 1 tube — — FDA listed —
Equate Antibiotic Plus Pain Relief 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g 49035-0847-05 WalMart 1 tube — — FDA listed —
DG Health Antibiotic 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 55910-0061-64 Dolgencorp 1 tube — — FDA listed —
Family Care Antibiotic Pain Relief 0.33oz 10 mg/g; 10000 [USP'U]/g; 3.5 mg/g 65923-0578-33 United 1 tube — — FDA listed —
Premier Value Max Strength Antibiotic plus pain relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 68016-0296-05 Pharmacy 1 tube — — FDA listed —
Dual Action Cream 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 69396-0071-01 Trifecta 1 tube — — FDA listed —
Antibiotic and Pain Relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 69842-0754-58 CVS 1 tube — — FDA listed —
Neosporin Kids Plus Pain Relief 3.5 mg/g; 10000 [iU]/g; 10 mg/g 69968-0054-01 Kenvue 1 tube — — FDA listed —
Neosporin Plus Pain Relief First Aid Antibiotic/Pain Relieving 3.5 mg/g; 10000 [USP'U]/g; 10 mg/g 69968-0055-01 Kenvue 1 tube — — FDA listed —
first aid antibiotic and pain relief 3.5 mg/g; 10 mg/g; 10000 [USP'U]/g 79481-0809-00 Meijer, 1 tube — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2024
On the market since
Jan 2024
📍
2026
Currently FDA-listed
2 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII A2I8C7HI9T
    Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
  • UNII T5L8T28FGP
    Mineral oil is a clear, odorless liquid derived from crude oil. It acts as a lubricant and emollient in medications, helping pills slide smoothly during manufacturing and aiding moisture retention in topical products.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII B6E5W8RQJ4
    White petrolatum is a purified mineral oil product used as a lubricant and skin protectant in medications. It helps pills slide through manufacturing equipment and can soften or protect the skin when applied topically.

5 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesemulsifying wax, methylparaben, mineral oil, propylene glycol, purified water, white petrolatum

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerSTRATEGIC SOURCING SERVICES LLC
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code70677
First marketedJan 2024
Product typeHuman Otc Drug
Portfolio316 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 21 words ▾

Uses first aid to help prevent infection and for the temporary relief of pain or discomfort in minor: cuts scrapes burns

⏱️ Dosage and Administration 58 words ▾

Directions adults and children 2 years of age and older: clean the affected area apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily may be covered with a sterile bandage children under 2 years of age: ask a doctor

⚠️ Warnings 104 words ▾

Warnings For external use only. Do not use in the eyes over large areas of the body if you are allergic to any of the ingredients Ask a doctor before use if you have deep or puncture wounds animal bites serious burns Stop use and ask a doctor if you need to use longer than 1 week condition persists or gets worse symptoms persist for more than 1 week, or clear up and occur again within a few days rash or other allergic reaction develops Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 21 words ▾

Other information store at 20° to 25°C (68° to 77°F) see carton or tube crimp for lot number and expiration date

🧪 Active Ingredient 27 words ▾

Active ingredients (each gram contains) Purpose Neomycin sulfate 3.5 mg First aid antibiotic Polymyxin B sulfate 10,000 units First aid antibiotic Pramoxine HCl 10 mg External analgesic

🧪 Inactive Ingredients 13 words ▾

Inactive ingredients emulsifying wax, methylparaben, mineral oil, propylene glycol, purified water, white petrolatum

🎯 Purpose 27 words ▾

Active ingredients (each gram contains) Purpose Neomycin sulfate 3.5 mg First aid antibiotic Polymyxin B sulfate 10,000 units First aid antibiotic Pramoxine HCl 10 mg External analgesic

📄 Do Not Use 21 words ▾

Do not use in the eyes over large areas of the body if you are allergic to any of the ingredients

📄 Ask a Doctor Before Use If 16 words ▾

Ask a doctor before use if you have deep or puncture wounds animal bites serious burns

📄 Stop Use and Ask a Doctor If 43 words ▾

Stop use and ask a doctor if you need to use longer than 1 week condition persists or gets worse symptoms persist for more than 1 week, or clear up and occur again within a few days rash or other allergic reaction develops

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Questions or Comments 10 words ▾

Questions? call 833-358-6431 Monday to Friday 9:00am to 7:00pm EST

📄 Package Label / Principal Display Panel 48 words ▾

PRINCIPAL DISPLAY PANEL - 14.2 g Tube Carton Foster & Thrive™ MAXIMUM STRENGTH Antibiotic Cream + Pain Relief Neomycin Sulfate • Polymyxin B Sulfate • Pramoxine HCl FIRST AID ANTIBIOTIC / PAIN RELIEVING CREAM NET WT ½ oz (14.2 g) PRINCIPAL DISPLAY PANEL - 14.2 g Tube Carton

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Neomycin, polymyxin B, pramoxine hydrochloride — the ingredient across all brands.

Top reported reactions

Drug Hypersensitivity7
Constipation6
Rash6
Fatigue5
Pain5
Urinary Tract Infection5
Decreased Appetite4

Age at onset

Adult8
Elderly3

Reporter sex

68 reports
Male · 38%
Female · 62%

Serious outcomes

Hospitalization18
Life-threatening2
Death2
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 8 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
← 70677-1217-01 · STRATEGIC 70677-1219-01 · STRATEGIC →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.