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Clean and Clear Advantage Acne Spot Treatment Salicylic Acid 20 mg/mL Lotion — NDC 69968-0126-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Clean and Clear Advantage Acne Spot Treatment Salicylic Acid 20 mg/mL Lotion — NDC 69968-0126-1 (Billing 69968-0126-01)

by Kenvue Brands LLC · 1 TUBE in 1 CARTON / 22 mL in 1 TUBE

This is a package of Clean and Clear Advantage Acne Spot Treatment Salicylic Acid 20 mg/mL Lotion from Kenvue Brands LLC, marketed since Oct 2006 and currently FDA-listed. It is this product's only package size.

NDC 69968-0126-01
🏷️ FDA NDC (as labeled) 69968-0126-1 billing pads the package segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

NDC database record

One package, one record: these facts belong to NDC 69968-0126-1 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
69968 labeler · 0126 product · 1 package
Package marketed since
Oct 1, 2006
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC)
0381370039914
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 69968-0126-1
Product NDC 69968-0126
11-digit billing NDC 69968012601
RxCUI 103568
UNII O414PZ4LPZ
UPC 0381370039914
Application # M006
SPL Set ID b907a42d-14ff-4ea1-b197-28f8340c9ed2
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2006-10-01
Route TOPICAL
Dosage form LOTION
Substance SALICYLIC ACID
Quick answers
  • RxCUI (RxNorm): 103568
Why two NDCs? The FDA registers this code as 69968-0126-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 69968-0126-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Salicylic acid and derivatives class.

Drug family (ATC) Salicylic acid and derivatives, Other antifungals for topical use, Antiinflammatory agents, non-steroids
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📖 What it is MedlinePlus · NLM

Topical salicylic acid is used to help clear and prevent pimples and skin blemishes in people who have acne. Topical salicylic acid is also used to treat skin conditions that involve scaling or overgrowth of skin cells such as psoriasis (a skin disease in which red, scaly patches form on some areas of the body), ichthyoses (inborn conditions that cause skin dryness and scaling), dandruff, corns, calluses, and warts on the hands or feet. Topical salicylic acid should not be used to treat genital warts, warts on the face, warts with hair growing from them, warts in the nose or mouth, moles, or b...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • It is used in a facial routine for acne-prone and oil-prone skin. The routine includes a cleanser, serum, toner and emulsion. Salicylic acid helps loosen and shed dead skin cells.
  • Use the cleanser morning and evening, and the serum in the morning after cleansing. Use the toner in the evening on dry skin, and the emulsion at night after cleansing. Avoid your...
  • Mild stinging, burning, itching, dryness and extra peeling can happen. If dryness or peeling bothers you, try using the serum or toner every other day. If it gets excessive, stop a...
  • It is best not to. Using another topical acne medication at the same time makes irritation and dryness more likely. If you get irritated, use only one at a time.
📖 Read our full Salicylic Acid Topical guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
69968-0126-01 You're viewing this Main listing 1 TUBE in 1 CARTON / 22 mL in 1 TUBE 2006-10-01 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
SkinMedica Acne Clarifying Treatment 20 mg/mL 00023-1230-01 Allergan, 1 tube — — FDA listed —
Ultra Clear Treatment 2 g/100mL 10028-0051-01 ULTRACEUTICALS 50 ml — — FDA listed —
Oxygenetix Oxygenating Foundation Acne Control 2 g/100mL 10258-0101-11 COLONIAL 15 ml — — Discontinued —
Dr. Sheffield Psoriasis Medicated Moisturizer 20 mg/g 11527-0478-64 Sheffield 1 tube — — FDA listed —
Meijer Oil Free Acne Wash Pink Grapefruit Foaming Scrub 20 mg/mL 41250-0963-15 MEIJER 198.1 ml — — FDA listed —
Daily Meds 20 mg/mL 49825-0100-10 Bioelements, 1 bottle — — FDA listed —
IT Cosmetics Bye Bye Breakout Concentrated Derma Serum Acne Treatment 20 mg/mL 49967-0026-01 L'Oreal 1 bottle — — FDA listed —
Maybelline Dream Pure BB Beauty Balm 20 mg/mL 49967-0957-01 L'Oreal 30 ml — — FDA listed —
Clear Acne Face Moisturizer 28.8 mg/mL 50718-0033-01 Kamedis 1 bottle — — FDA listed —
ageLOC LumiSpa Blemish Serum 20 mg/mL 62839-2539-01 NSE 1 bottle — — FDA listed —
St. Ives Blemish and Blackhead Control Apricot Scrub .02 g/g 64942-1861-01 CONOPCO 22 g — — FDA listed —
Monat Be Clarified Acne-Clearing Moisturizer 20 mg/mL 68577-0107-00 Cosmax 1 bottle — — FDA listed —
Skin Pharmacy Advanced Acne Therapy Overnight Salicylic Acid 20 g/2mL 68634-0057-01 AMCOL 1 tube — — FDA listed —
Skinpharmacy Advanced Acne Therapy Overnight Salicylic Acid 20 mg/mL 69842-0066-01 CVS 1 tube — — FDA listed —
Clean and Clear Advantage Acne Spot Treatment 20 mg/mLthis 69968-0126-01 Kenvue 1 tube — — FDA listed —
LBRI PURE n NATURAL KlearAway 20 mg/mL 71238-0464-05 L'BRI 5 ml — — FDA listed —
Peace Out Acne Serum 20 mg/mL 71494-0102-30 Peace 1 bottle — — FDA listed —
amazon basics advanced blemish spot treatment Acne medication 20 mg/mL 72288-0386-01 AMAZON.COM 1 tube — — FDA listed —
SA Acne Spot Treatment 20 mg/g 73318-7003-09 Skin 1 bottle — — FDA listed —
Multi-Action Clear - Acne Clearing Treatment 2% Salicylic Acid 2 g/100mL 76147-0301-07 StriVectin 1 tube — — FDA listed —
Byoma Acne Control Body 20 mg/mL 84821-0004-01 Byoma 400 ml — — FDA listed —
Acne Cleanser W/ Salicylic Acid 20 mg/mL 62742-4107-01 Allure 177 ml — — FDA listed —
Overnight Clearing 20 mg/mL 68479-0706-00 Dermalogica, 2 ml — — FDA listed —
Cetaphil Gentle Clear Clarifying Acne Cleanser 20 mg/mL 00299-4119-00 Galderma 124 ml — — FDA listed —
Cetaphil Acne Relief Body Wash 20 mg/mL 00299-4121-00 Galderma 591 ml — — Discontinued —
Differin Acne Clearing Body Wash 20 mg/mL 00299-4131-00 Galderma 295 ml — — FDA listed —
Artistry Studio Done With Zit Acne Treatment Clearing Gel 20 mg/mL 10056-0045-00 Access 1 tube — — FDA listed —
Doo Gro Anti-Dandruff Vitalizer 20 mg/mL 12022-0006-00 J. 100 ml — — FDA listed —
Acne Cleansing 20 mg/mL 49527-0045-01 CLINIQUE 1 tube — — FDA listed —
La Roche Posay Laboratorie Dermatologique Effaclar Medicated Cleanser 20 mg/mL 49967-0023-01 L'Oreal 200 ml — — FDA listed —
Garnier Clean Blackhead Eliminating Scrub 20 mg/mL 49967-0035-01 L'Oreal 150 ml — — FDA listed —
Thayers Since 1847 Natural Remedies Blemish Clearing Witch Hazel Aloe Vera Formula Cleanser 20 mg/mL 49967-0051-01 L'Oreal 118 ml — — FDA listed —
CeraVe Developed with Dermatologists Acne Control Cleanser 20 mg/mL 49967-0138-01 L'Oreal 237 ml — — FDA listed —
CeraVe Developed with Dermatologists Acne Control Acne Treatment 20 mg/mL 49967-0172-01 L'Oreal 1 tube — — FDA listed —
Vichy Laboratoires Normaderm Phytoaction Acne Control Daily Moisturizer 20 mg/mL 49967-0606-01 L'Oreal 1 bottle — — FDA listed —
Vichy Laboratoires Normaderm Acne Control Daily Moisturizer 20 mg/mL 49967-0660-01 L'Oreal 1 bottle — — FDA listed —
Dr. Dennis Gross Alpha Beta On the Spot Eliminator 20 mg/mL 51326-0057-01 Topiderm, 1 tube — — FDA listed —
Equate Beauty Quick Action Pads Salicylic Acid Acne Treatment 20 mg/mL 61805-0117-01 Bath 90 patches — — FDA listed —
Vichy Laboratoires Normaderm Acne Control Moisturizer 20 mg/mL 69625-0661-01 COSMETIQUE 1 bottle — — FDA listed —
MILANI ERASE BASE BLEMISH CONTROL PRIMER Salicylic Acid 20 mg/mL 71435-0005-00 New 30 ml — — FDA listed —
Dr. C. Tuna Acne Clear Complexion Cleanser 20 mg/mL 74690-0010-01 Farmasi 1 tube — — FDA listed —
Peach and Lily Peaches Slices Acne Clarifying Cleanser 20 mg/mL 81515-0500-01 Peach 120 ml — — FDA listed —
VANIBISS BUTT and THIGHS Acne Treatment Cream 20 mg/mL 81890-0192-00 Vanibiss 1 jar — — FDA listed —
SIMPLY VITAL Acne Face Cream 20 mg/mL 82460-0272-00 ALPHA 60 ml — — FDA listed —
Skin Laundry. Clean Slate Exfoliating 2 Salicylic Acid Treatment Gel Cleanser Cleanse Exfoliate 20 mg/mL 83727-0294-00 Skin 150 ml — — FDA listed —
Vichy Laboratoires Normaderm Acne Control Daily Moisturizer 20 mg/mL 82046-0617-01 LOreal 1 bottle — — FDA listed —
Skinkure Acne Eraser Spot Treatment 20 mg/mL 83865-0100-10 SKINKURE, 30 ml — — FDA listed —
Acne Scrub 20 mg/mL 41163-0821-99 United 124 ml — — FDA listed —
Acne Scrub 20 mg/mL 49035-0821-99 Walmart 124 ml — — FDA listed —
Thayers Since 1847 Natural Remedies Blemish Clearing Witch Hazel Aloe Vera Formula Balm 20 mg/mL 49967-0530-01 L'Oreal 118 ml — — FDA listed —
Atrix Acne Treatment 20 mg/mL 59088-0446-05 PureTek 59 ml — — FDA listed —
CVS Health Advanced Acne Spot Treatment 20 mg/mL 69842-0464-52 CVS 1 tube — — FDA listed —
Mens Rogaine 2% Salicylic Acid Anti-Dandruff Plus Conditioner 20 mg/mL 69968-0954-02 Kenvue 248 ml — — FDA listed —
Peace Out Acne Moisturizer 20 mg/mL 71494-0008-01 Peace 1 jar — — FDA listed —
Acne Body Wash 20 mg/mL 82575-0110-30 Curology 267 ml — — FDA listed —
Body Wash 20 mg/mL 36800-0354-23 Topco 251 ml — — FDA listed —
Walgreens Oil-Free Acne Wash Salicylic Acid 20 mg/mL 00363-3473-01 Walgreen 270 ml — — FDA listed —
Ology Acne Clearing Body Mist 20 mg/mL 00363-9659-10 Walgreens 1 tube — — FDA listed —
The INKEY List C 50 Serum 20 mg/mL 81136-0020-01 Brand 1 bottle — — Discontinued —
Acne Treatment Gel 20 mg/mL 31720-0301-08 S+ 1 bottle — — FDA listed —
Kiehls Gently Effective Acne Treating Cleansing 20 mg/mL 49967-0464-01 L'Oreal 125 ml — — FDA listed —
Acne Deep Pore Cleansing Wash 20 mg/mL 54108-3700-01 derma 175 ml — — FDA listed —
MDacne Customized Acne Treatment Salicylic Acid 20 mg/mL 71804-0533-00 MDAlgorithms 1 tube — — FDA listed —
Body Wash 20 mg/mL 72288-0353-23 Amazon.com 251 ml — — FDA listed —
Acne Body Wash 20 mg/mL 82575-0200-20 Curology 200 ml — — FDA listed —
Anew Bare Acne Clearing Treatment 2% Salicylic Acid 20 mg/mL 10096-2932-01 THE 1 tube — — FDA listed —
Meijer oil Free Acne Wash Facial Cleanser Pink Grapefruit Acne medication 20 mg/mL 41250-0346-01 Meijer 177 ml — — FDA listed —
DermaClear Serum 20 mg/mL 62742-4069-02 Allure 1 tube — — FDA listed —
Neutrogena Oil Free Acne Wash 20 mg/mL 69968-0516-06 Kenvue 177 ml — — FDA listed —
LEROSETT Botanical Acne Cleanser 20 mg/mL 84463-0507-00 GUNILLA 200 ml — — FDA listed —
Acne Scrub 20 mg/mL 36800-0821-99 Topco 124 ml — — FDA listed —
ACNE SolutionS CLINICAL ADVANCED CLEARING gel 20 mg/mL 49527-0221-01 CLINIQUE 1 bottle — — Discontinued —
WinCo Foods Oil Free Acne Wash with Pink Grapefruit Acne treatment 20 mg/mL 67091-0372-06 WINCO 177 ml — — FDA listed —
Alumier MD Acne Clarifying Cleanser 20 mg/mL 69473-0001-01 Alumier 1 bottle — — FDA listed —
Alumier MD Acne Balancing Serum 20 mg/mL 69473-0002-01 Alumier 1 bottle — — FDA listed —
Salicylic Acid 2% Solution 20 mg/mL 72208-0221-01 Deciem 1 bottle — — FDA listed —
Acne Body Wash 20 mg/mL 82575-0100-10 Curology 100 ml — — FDA listed —
Signature Care Oil Free Acne Wash Pink Grapefruit Foaming Scrub 20 mg/mL 21130-0734-15 Safeway, 198 ml — — FDA listed —
Meijer Clarifying Body Wash Acne Treatment 20 mg/mL 41250-0627-01 Meijer 250 ml — — FDA listed —
Walgreens Pink Grapefruit Acne Wash 20 mg/mL 00363-0406-15 WALGREEN 198.1 ml — — FDA listed —
Milani Erase Base Blemish Control Primer 20 mg/mL 68577-0103-00 Cosmax 1 tube — — FDA listed —
Neutrogena Oil Free Acne Stress Control Power Clear Scrub 20 mg/mL 69968-0073-04 Kenvue 125 ml — — FDA listed —
Neutrogena Oil-Free Acne Stress Control Power-Cream Wash 20 mg/mL 69968-0519-06 Kenvue 177 ml — — FDA listed —
Clean and Clear Acne Spot Treatment 20 mg/mL 69968-0804-01 Kenvue 1 tube — — FDA listed —
Acne Scrub 20 mg/mL 72288-0821-99 Amazon.com 124 ml — — FDA listed —
Duolaq 20 mg/mL 87110-0001-01 METHODIQ 1 bottle — — FDA listed —
CeraVe Acne Clay-to-Foam Cleanser 20 mg/mL 49967-0600-01 LOreal 15 tubes — — FDA listed —
Acne Wash 20 mg/mL 55910-0947-30 Old 177 ml — — FDA listed —
Neutrogena Oil-Free Acne Wash Pink Grapefruit Foaming Scrub 20 mg/mL 69968-0247-04 Kenvue 124 ml — — FDA listed —
Neutrogena Rapid Clear Acne Eliminating Spot 20 mg/mL 69968-0825-01 Kenvue 1 tube — — FDA listed —
Tiege Hanley 20 mg/mL 71714-0003-24 Tiege 24 ml — — FDA listed —
pHisoderm CLEAN ANTI-BLEMISH BODY WASH 20 mg/mL 10742-1234-01 The 295 ml — — FDA listed —
pHisoderm CLEAN ANTI-BLEMISH FACIAL CLEANSER 20 mg/mL 10742-1235-01 The 177 ml — — FDA listed —
Oxy Total Care Creamy Facial Cleanser 20 mg/mL 10742-1316-01 The 148 ml — — FDA listed —
Target Up and Up Oil Free Acne Wash Pink Grapefruit Foaming Scrub 20 mg/mL 11673-0068-15 TARGET 198.1 ml — — FDA listed —
Vichy Laboratoires Normaderm Acne Control Daily Moisturizer 20 mg/mL 69625-0617-01 Cosmetique 1 bottle — — FDA listed —
Neutrogena Rapid Clear Acne Eliminating Spot 20 mg/mL 69968-0472-01 Kenvue 1 tube — — FDA listed —
The INKEY List Beta Hydroxy Acid Serum 20 mg/mL 81136-0021-01 Brand 1 bottle — — FDA listed —
Body Wash 20 mg/mL 49035-0073-23 Walmart 250 ml — — FDA listed —
SkinCeuticals Clarifying Exfoliating Cleanser 20 mg/mL 49967-0468-01 L'Oreal 150 ml — — FDA listed —
Gm Collin Puracne 20 mg/mL 64127-0195-01 Laboratoires 1 tube — — FDA listed —
Walgreens Acne Control Gel 20 mg/mL 00363-0269-83 WALGREEN 1 tube — — FDA listed —
Equate 20 mg/mL 79903-0317-68 Walmart 200 ml — — FDA listed —
Acne Free BLACKHEAD REMOVING SCRUB 2 Salicylic Acid with Charcoal 20 mg/mL 80861-0012-01 AcneFree 150 ml — — FDA listed —
The INKEY List Salicylic Acid Cleanser 20 mg/mL 81136-0019-01 Brand 1 bottle — — FDA listed —
Starface Acne Spot Treatment 20 mg/mL 83171-0003-01 Starface 1 tube — — FDA listed —
Byoma Acne Treatment Spot 20 mg/mL 84821-0008-01 Byoma 15 ml — — FDA listed —
Hero Cosmetics Pimple Correct Salicylic Acid Acne Treatment 20 mg/mL 10237-0003-00 Church 1 tube — — FDA listed —
Proactiv Plus Retexturizing Toner 20 mg/mL 11410-0051-00 Alchemee, 1 bottle — — FDA listed —
H.E.B. Oil Free Daily Acne Scrub 20 mg/mL 37808-0342-73 H.E.B 125 ml — — FDA listed —
La Roche Posay Effaclar Medicated Cleanser 20 mg/mL 49967-0402-01 L'Oreal 200 ml — — FDA listed —
CeraVe Developed with Dermatologists Acne Control Cleanser Oil Absorbing Technology 20 mg/mL 49967-0840-01 L'Oreal 473 ml — — FDA listed —
Cetaphil Gentle Clear Pore Clearing Acne Cleanser 20 mg/mL 00299-4143-00 Galderma 237 ml — — FDA listed —
Vichy Laboratoires Normaderm Phytoaction Acne Control Moisturizer 20 mg/mL 69625-0605-01 COSMETIQUE 1 bottle — — FDA listed —
CVS Clarifying Body Wash Acne Treatment 20 mg/mL 69842-0583-01 CVS 250 ml — — FDA listed —
Neutrogena Oil-Free Acne Wash Daily Scrub 20 mg/mL 69968-0075-04 Kenvue 124 ml — — FDA listed —
Neutrogena Oil Free Acne Wash Cleanser 20 mg/mL 69968-0155-06 Kenvue 200 ml — — FDA listed —
Neutrogena Oil Free Acne Wash Pink Grapefruit Foaming Scrub 20 mg/mL 69968-0610-02 Kenvue 59 ml — — FDA listed —
Peace Out Acne Cleanser 20 mg/mL 71494-0103-01 Peace 1 tube — — FDA listed —
Acne Gel Pen 20 mg/mL 71714-0004-01 Tiege 1.3 ml — — FDA listed —
L BRI Klearaway 20 mg/mL 71238-0922-05 L'BRI 5 ml — — FDA listed —
salicylic acid 20 mg/mL 83324-0182-42 Chain 124 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2006
On the market since
Oct 2006
📍
2026
Currently FDA-listed
20 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Salicylic Acid Topical inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
  • UNII 5138Q19F1X
    Ammonia is a colorless gas made from nitrogen and hydrogen. It's used in medicines as a pH buffer to maintain the correct acidity level and help keep the product stable.
  • UNII F5UM2KM3W7
    Benzalkonium chloride is a chemical compound that works as a preservative and antimicrobial agent in medications. It prevents bacterial and fungal growth in liquid formulations to keep the product safe during storage and use.
  • UNII 3XUS85K0RA
    Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
  • UNII GC844VRD7E
    A synthetic fatty acid ester derived from plant oils and lactic acid. It acts as an emulsifier and solvent to help mix oil and water-based ingredients and improve how the medicine dissolves or spreads in the body.
  • UNII E4F12ROE70
    A refined mineral oil derived from crude petroleum containing 13 to 14 carbon chains. It acts as a solvent, emollient, and carrier in topical formulations to help dissolve active ingredients and improve product texture and spreadability.
  • UNII 8TY5YO42NJ
    Capryloyl glycine is a mild, skin-conditioning ingredient made from a natural fatty acid and the amino acid glycine. In medicines, it acts as a surfactant and preservative booster, helping the product spread evenly and resist contamination.
  • UNII ITP1Q41UPF
    A plant extract from Atlas cedar bark used as a natural fragrance or flavoring agent in medicines. It may also help preserve the product or improve its sensory appeal.
  • UNII A7EVH2RK4O
    Cetyl lactate is a waxy compound made from lactic acid and cetyl alcohol. It works as an emulsifier and thickener to help mix oil and water ingredients and give the medicine the right texture.
  • UNII XE54U569EC
    A natural essential oil extracted from cinnamon bark. It's used as a flavoring agent to mask bitter tastes and improve the flavor of medicines.
  • UNII H2KVQ74JM4
    A compound derived from coconut oil that acts as a conditioning agent and surfactant. It helps stabilize and thicken liquid formulations while reducing static and improving texture in topical products.
  • UNII 0THT5PCI0R
    A silicone-based liquid that helps distribute active ingredients evenly throughout topical products. It acts as a solvent and emollient, allowing medicines to spread smoothly on skin while improving texture and absorption.
  • UNII 63ZP7I1BQO
    A plant-derived thickening agent made from xanthan gum that has been chemically modified. It helps give the medicine the right texture and consistency, and may act as a binder or stabilizer in tablets and liquids.
  • UNII MP1J8420LU
    A salt derived from edetic acid that binds to trace metals in medicines. It serves as a chelating agent and preservative to prevent metal-catalyzed breakdown of the drug and extend shelf life.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII Z95S6G8201
    A synthetic surfactant derived from lauryl alcohol and ethylene oxide. It helps dissolve and mix oily and watery ingredients in liquid formulations, and may improve how the medicine spreads or is absorbed.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII 7T1F30V5YH
    A synthetic emulsifier derived from sorbitol and oleic acid. It helps mix oil and water-based ingredients together and keeps them from separating in liquid formulations.
  • UNII BI6C7YO419
    A synthetic oily liquid derived from petroleum-based materials. It functions as an emulsifier and solubilizer in medicines, helping blend water and oil-based ingredients and keeping them mixed throughout the product's shelf life.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII M6S840WXG5
    Purslane is a plant-derived ingredient used in pharmaceuticals as a natural source of beneficial compounds. It functions as an antioxidant and anti-inflammatory agent to help stabilize the formula and support product shelf life.
  • UNII Z711V88R5F
    Sarcosine is a small amino acid naturally found in foods and the body. In medicines, it acts as a buffer and pH regulator to keep the formulation stable and prevent unwanted chemical changes.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII 101I4J0U34
    Witch hazel is a plant extract obtained from the leaves and bark of the North American shrub Hamamelis virginiana. It functions as an astringent and skin-conditioning agent in topical products, helping to tone and prepare the skin.

24 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesAlcohol Denat., Water, Hamamelis Virginiana (Witch Hazel) Water, Polyacrylamide, Glycerin, Cyclopentasiloxane, C13-14 Isoparaffin, C12-15 Alkyl Lactate, Alcohol, Phenoxyethanol, Cetyl Lactate, PPG-2 Isoceteth-20 Acetate, Cocamidopropyl PG-Dimonium Chloride Phosphate, Laureth-7, Polysorbate 20, Phenethyl Dimethicone, Fragrance, Dehydroxanthan Gum, Propylene Glycol, Benzalkonium Chloride, Ammonia, Tetrasodium EDTA, Butylene Glycol, Capryloyl Glycine, Sarcosine, Cinnamomum, Zeylanicum Bark Extract, Cedrus Atlantica Bark Extract, Portulaca Oleracea Extract

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerKenvue Brands LLC
FDA applicationM006 (OTC MONOGRAPH DRUG)
Labeler code69968
First marketedOct 2006
Product typeHuman Otc Drug
Portfolio567 products on file

More NDCs from Kenvue Brands LLC labeler code 69968

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage 6 words ▾

Use For the treatment of acne

⏱️ Dosage and Administration 69 words ▾

Directions clean the skin thoroughly before applying this product. cover the entire affected area with a thin layer one to three times daily because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce application to once a day or every other day

⚠️ Warnings 76 words ▾

Warnings For external use only. Flammable, keep away from open fire or flame. When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. If eye contact occurs, flush thoroughly with water. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 50 words ▾

Other Information Store at room temperature. Sunburn Alert This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

🧪 Active Ingredient 5 words ▾

Active Ingredient Salicylic Acid (2%)

🧪 Inactive Ingredients 60 words ▾

Inactive Ingredients Alcohol Denat., Water, Hamamelis Virginiana (Witch Hazel) Water, Polyacrylamide, Glycerin, Cyclopentasiloxane, C13-14 Isoparaffin, C12-15 Alkyl Lactate, Alcohol, Phenoxyethanol, Cetyl Lactate, PPG-2 Isoceteth-20 Acetate, Cocamidopropyl PG-Dimonium Chloride Phosphate, Laureth-7, Polysorbate 20, Phenethyl Dimethicone, Fragrance, Dehydroxanthan Gum, Propylene Glycol, Benzalkonium Chloride, Ammonia, Tetrasodium EDTA, Butylene Glycol, Capryloyl Glycine, Sarcosine, Cinnamomum, Zeylanicum Bark Extract, Cedrus Atlantica Bark Extract, Portulaca Oleracea Extract

🎯 Purpose 3 words ▾

Purpose Acne Medication

📄 When Using This Product 44 words ▾

When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. If eye contact occurs, flush thoroughly with water.

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Questions or Comments 7 words ▾

Questions? Call toll‐free 1-877-754-6411 or 215-273-8755 (collect).www.cleanandclear.com

📄 Package Label / Principal Display Panel 41 words ▾

PRINCIPAL DISPLAY PANEL - 22 mL Tube Carton Clean & Clear ® advantage acne spot treatment salicylic acid acne medication OIL-FREE +WITCH HAZEL 100% of people showed clearer skin in just one day won't overdry skin

0.75FL. OZ. (22mL) Clean001

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Salicylic Acid (matched by generic name) — the program that covers self-administered drugs. 2 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Salicylic Acid. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$11.2K
Claims incl. refills
43
Beneficiaries
35
Spend / beneficiary
$319.01
Spend / claim
$259.66
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Kenvue Brands LLC. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Kenvue Brands LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.