NDC 70163-0029-02 — Tree Pollen Acer Negundo, Acer Rubrum

🆔 Identity & classification

FDA NDC (as labeled) 70163-0029-2

Product NDC 70163-0029

11-digit billing NDC 70163002902

UNII P6K070AR8V, 700NK45C76, YKH834O4BH, 492225Q21H, 3029988O2T, 93963RFO1P +12 more

UPC 0371400707012

SPL Set ID feea837e-7ce3-4575-8cb8-451f5385cf97

Established class (EPC) Non-Standardized Pollen Allergenic Extract; alpha-Adrenergic Agonist; beta-Adrenergic Agonist; Catecholamine; Non-Standardized Food Allergenic Extract

Mechanism of action Adrenergic alpha-Agonists; Adrenergic beta-Agonists

Physiologic effect Increased Histamine Release; Cell-mediated Immunity; Increased IgG Production

Chemical class Pollen; Allergens; Catecholamines; Dietary Proteins; Vegetable Proteins

DEA schedule Non-controlled

Marketing category UNAPPROVED HOMEOPATHIC

Marketing status On market

FDA listing status Listed (active directory)

Marketing start 2026-03-04

Route ORAL

Dosage form LIQUID

Substance ACER NEGUNDO POLLEN; ACER RUBRUM POLLEN; EPINEPHRINE; ONION; ARSENIC TRIIODIDE; BETULA NIGRA POLLEN; EUPHRASIA STRICTA; FRAXINUS AMERICANA POLLEN; HISTAMINE DIHYDROCHLORIDE; LIGUSTRUM VULGARE POLLEN; LIQUIDAMBAR STYRACIFLUA POLLEN; MORUS ALBA POLLEN; PINU

Why two NDCs? The FDA registers this code as 70163-0029-2 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 70163-0029-02. Same drug, same package — only the format differs.

Where does this data come from?

Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerNaturalCare

Labeler code70163

First marketedMar 2026

Product typeHuman Otc Drug

Portfolio42 products on file

🔎 All NDCs from NaturalCare

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).

Where does this data come from?

Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is an unapproved homeopathic liquid product taken by mouth that contains diluted forms of tree pollens (including maple, birch, ash, oak, and pine), onion, epinephrine, histamine, and arsenic compound. In homeopathic practice, these ingredients are traditionally used to address allergy symptoms and respiratory concerns. Homeopathic products are marketed based on historical use and traditional preparation methods, and the FDA does not evaluate them for safety or effectiveness.

Patient education

📘 MedlinePlus patient leaflet ↗

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →

Where does this data come from?

Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

UNII 3K9958V90M
A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

2 inactive ingredients listed in the exact product block matched to this NDC.

The official label also states20% alcohol, purified water

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?

Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?

No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.

Why might an inactive ingredient be missing?

Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.

Can inactive ingredients matter?

Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price system	Per mL	Per package
Retail pharmacies payNADAC · weekly	Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo	No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly	No Part D plan price is available for this NDC in our data.

ℹ️

No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.

Where does this data come from?

NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

Product	Labeler	Pack	NADAC/unit	TE	Status	Price vs. this
Tree Pollen 12 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 6 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mLthis 70163-0029-02	NaturalCare	1 bottle	—	—	FDA listed	—

About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.

Where does this data come from?

Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️

2026

On the market since

Mar 2026

📍

2026

Currently FDA-listed

listed with the FDA

🔒

·

No generic listed yet

brand only

ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?

Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

🔬 Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Tree Pollen (this brand).

Top reported reactions

Cardiopulmonary Failure1

Coma1

Age at onset

Adult1

Reporter sex

Serious outcomes

Death1

Where does this data come from?

Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

📦 Packaging — all sizes for this product

Package NDC	Description	Marketing start	Status
70163-0029-02 You're viewing this	1 BOTTLE, DROPPER in 1 CARTON (70163-0029-2) / 30 mL in 1 BOTTLE, DROPPER (70163-0029-1)	2026-03-04	Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product Homeopathic listing

About homeopathic listings

Tree Pollen Acer Negundo, Acer Rubrum, Adrenalinum, Allium Cepa, Arsenicum Iodatum, Betula Nigra, Euphrasia Officinalis, Fraxinus Americana, Histaminum Hydrochloricum, Ligustrum Vulgare, Liquidambar Styraciflua, Morus Alba, Pinus Strobus, Populus Deltoides, Quercus R 12 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 6 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL; 6 [hp_X]/mL; 12 [hp_X]/mL LIQUID is listed under the homeopathic marketing category. An NDC listing in this category does not by itself establish FDA approval, and FDA does not evaluate homeopathic products for effectiveness. This page reports the listing data as published.

What data is (and isn’t) available for this NDC — tap to expand

NDC identity (package / product / labeler codes)	✓ Available
Labeler	✓ Available
Product & package description	✓ Available
Marketing category & status	✓ Available
Active ingredient / dosage form / route	✓ Available
FDA label (SPL via DailyMed)	✓ Available
Package photos	✓ Available
Inactive ingredients (structured)	✓ Available
NADAC pharmacy acquisition price (CMS)	— Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data	— Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk	— Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD)	— Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.

“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?

An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Unapproved Homeopathic". Products approved under an application carry an NDA, ANDA, or BLA number.

Why is there no price listed?

The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.

Is the NDC printed on the package the same as the 11-digit billing NDC?

Yes, they identify this exact package in different formats. The FDA registers it as 70163-0029-2, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 70163-0029-02, written without dashes as 70163002902. The Identity section at the top of this page lists every form of this code.

What do the three segments of this NDC mean?

In 70163-0029-02, the first segment (70163) is the labeler code FDA assigned to NaturalCare; the middle segment (0029) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (02) identifies this exact package size and type. Together they name one specific package of one specific product.

Is this package still being marketed?

Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by NaturalCare. Listing status can change — the directory data on this page refreshes weekly.

Who lists this product with the FDA?

NaturalCare is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.

Do I need a prescription for this product?

This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.

This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.

Where does this data come from?

Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.

🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose

🎯 Indications and Usage 42 words ▾

USES: May help temporarily relieve allergy symptoms ■ congestion ■ headache ■ itchy, watery eyes ■ sneezing* *Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated. Individual responses may vary, and this product may not work for everyone.

⏱️ Dosage and Administration 59 words ▾

DIRECTIONS: Adults and children 12 years and over: ■ take 15 drops under the tongue every 3-4 hours ■ sensitive persons and asthma sufferers take 1-3 drops and wait 3 hours then continue with regular dosage provided ■ if allergy or asthma symptoms develop, discontinue use ■ Consult a physician for use in children under 12 years of age

⚠️ Warnings 79 words ▾

WARNINGS: Stop use and ask a doctor if ■ symptoms do not improve in 5 days or new symptoms appear ■ you are as asthma sufferer with severe allergies If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Do not use if tamper evident seal is missing or open. ■ Store tightly closed at room temperature (65-80ºF)

🧪 Active Ingredient 96 words ▾

ACTIVE INGREDIENT: (in each drop) Allium Cepa 6X 5.88%, Arsenicum Iodatum 6X 5.88%, Euphrasia Officinalis 6X 5.88%, Sabadilla 6X 5.88%, Sanguinaria Canadensis 6X 5.88%, Histaminum Hydrochloricum 12X 5.88%, Acer Negundo (box elder) 12X 5.88%, Acer Rubrum (red maple) 12X 5.88%, Betula Nigra (birch) 12X 5.88%, Fraxinus Americana (white ash) 12X 5.88%, Ligustrum Vulgare (privet) 12X 5.88%, Liquidambar Styraciflua (sweet gum) 12X 5.88%, Morus Alba (white mulberry) 12X 5.88%, Pinus Strobus (eastern white pine) 12X 5.88%, Populus Deltoides (eastern cottonwood) 12X 5.88%, Quercus Rubra (red oak) 12X 5.88%, Salix Nigra (black willow) 12X 5.88%, Adrenalinum 6X 0.10%.

🧪 Inactive Ingredients 6 words ▾

INACTIVE INGREDIENTS: 20% alcohol, purified water

🎯 Purpose 193 words ▾

PURPOSE: Allium Cepa – relieves allergy symptoms, Arsenicum Iodatum - relieves allergy symptoms, Euphrasia Officinalis - relieves allergy symptoms, Sabadilla - relieves allergy symptoms, Sanguinaria Canadensis - relieves allergy symptoms, Histaminum Hydrochloricum - antihistamine, Acer Negundo (box elder) – assist with the management of allergy symptoms, Acer Rubrum (red maple) - assist with the management of allergy symptoms, Betula Nigra (birch) - assist with the management of allergy symptoms, Fraxinus Americana (white ash) - assist with the management of allergy symptoms, Ligustrum Vulgare (privet) - assist with the management of allergy symptoms, Liquidambar Styraciflua (sweet gum) - assist with the management of allergy symptoms, Morus Alba (white mulberry) - assist with the management of allergy symptoms, Pinus Strobus (eastern white pine) - assist with the management of allergy symptoms, Populus Deltoides (eastern cottonwood) - assist with the management of allergy symptoms, Quercus Rubra (red oak) - assist with the management of allergy symptoms, Salix Nigra (black willow) - assist with the management of allergy symptoms, Adrenalinum – decongestant* *Claims based on traditional homeopathic practice, not accepted medical evidence.

Not FDA evaluated. Individual responses may vary, and this product may not work for everyone.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

🔗 Related NDC lookups

🧪 All Acer Negundo, Acer Rubrum, Adrenalinum, Allium Cepa, Arsenicum Iodatum, Betula Nigra, Euphrasia Officinalis, Fraxinus Americana, Histaminum Hydrochloricum, Ligustrum Vulgare, Liquidambar Styraciflua, Morus Alba, Pinus Strobus, Populus Deltoides, Quercus R NDCsSame ingredient 🏭 All NaturalCare labeler NDCsLabeler code 70163