AMAZON Maximim Strength Adult Nighttime Cough DM Dextromethorphan HBr, Doxylamine Succinate 30 mg/20mL; 12.5 mg/20mL Solution — NDC 72288-587-04 (Billing 72288-0587-04)
This is a package of AMAZON Maximim Strength Adult Nighttime Cough DM Dextromethorphan HBr, Doxylamine Succinate 30 mg/20mL; 12.5 mg/20mL Solution from AMAZON.COM SERVICES LLC, marketed since Feb 2026 and currently FDA-listed. It is this product's only package size.
NDC database record
One package, one record: these facts belong to NDC 72288-587-04 alone.
- Record
- FDA NDC Directory package listing · Human OTC drug
- Code segments
- 72288 labeler · 587 product · 04 package
- Package marketed since
- Feb 16, 2026
- Sample package
- No — commercial package
- Listing certified through
- Dec 31, 2027
- Barcode (UPC)
- 0000000000000
- FDA record last changed
- Jul 24, 2026
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
- RxCUI (RxNorm): 1115329
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 5, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 1, 2026
RxNorm drug class
This medicine belongs to the Uncompetitive N-methyl-D-aspartate Receptor Antagonist class.
Where does this data come from?
- RxClass (NLM) · catalog refreshed Oct 1, 2026
Clinical
Dextromethorphan is used to temporarily relieve cough caused by the common cold, the flu, or other conditions. Dextromethorphan will relieve a cough but will not treat the cause of the cough or speed recovery. Dextromethorphan is in a class of medications called antitussives. It works by decreasing activity in the part of the brain that causes coughing.
Read the full MedlinePlus article ↗This is an over-the-counter oral liquid cough syrup sold under the OTC monograph rule, meaning it follows FDA's standard formula for this product category. It contains dextromethorphan hydrobromide, a cough suppressant typically used to reduce coughing, and doxylamine succinate, a first-generation antihistamine commonly used to promote drowsiness. Together, these ingredients are typically used in nighttime cough products to address cough while helping with sleep.
Patient education
Supplement & herbal interactions
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 5, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
- CMS NADAC weekly file
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · refreshed Oct 5, 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Marketing end | Status |
|---|---|---|---|---|
| 72288-0587-04 You're viewing this Main listing | 1 BOTTLE in 1 CARTON / 118 mL in 1 BOTTLE | 2026-02-16 | — | Active |
Therapeutic equivalents
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA Orange Book · refreshed Oct 3, 2026
- CMS NADAC weekly file
Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
- FDA Orange Book · refreshed Oct 3, 2026
What it looks like
Where does this data come from?
- FDA label on DailyMed · label index refreshed Oct 5, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII XF417D3PSL
Anhydrous citric acid is a sour, crystalline powder derived from citric acid with water removed. In medicines, it acts as a buffer to control pH, adds tartness to improve taste, and helps tablets disintegrate.
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UNII WZB9127XOA
A synthetic red dye used to color medications and make them easier to identify. It serves as a colorant in tablets, capsules, and liquid formulations.
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UNII L7T10EIP3A
A cooling compound from mint plants used as a flavoring agent and to create a fresh sensation in medicines. It helps mask bitter tastes and improve how the product feels in the mouth.
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UNII 6DC9Q167V3
Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
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UNII OJ245FE5EU
Sodium benzoate is a salt derived from benzoic acid, a preservative. It's added to medicines to prevent growth of bacteria, fungi, and other microorganisms that could spoil the product.
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UNII 506T60A25R
Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
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UNII 96K6UQ3ZD4
Sucralose is a synthetic sweetener made from sugar. It's added to medicines to improve taste without adding calories, helping make bitter or unpleasant-tasting drugs easier to take.
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UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
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UNII TTV12P4NEE
Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.
9 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.- FDA label on DailyMed · label index refreshed Oct 5, 2026
- FDA openFDA NDC Directory · synced Oct 1, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
More NDCs from AMAZON.COM SERVICES LLC labeler code 72288
- Esomeprazole Magnesium 20 mg Capsule, Delayed Release NDC 72288-563-01
- omeprazole and sodium bicarbonate 20 mg; 1100 mg Capsule, Gelatin Coated NDC 72288-564-03
- NICOTINE MINI Nicotine Polacrilex 2 mg Lozenge NDC 72288-569-01
- Oral Antivavity Sodium fluoride .1 mg/mL Mouthwash NDC 72288-576-86
- basic care nicotine Nicotine Polacrilex 4 mg Gum, Chewing NDC 72288-577-06
- basic care daytime cold and flu nighttime cold and flu Acetaminophen, dextromethorphan HBr, doxylamine succinate, phenylephrine HCl Kit NDC 72288-580-72
- basic care infants pain and fever Acetaminophen 160 mg/5mL Suspension NDC 72288-590-16
- basic care daytime severe cold and flu nighttime severe cold and flu acetaminophen, dextromethorphan HBr, doxylamine succinate, guaifenesin, phenylephrine HCl Kit NDC 72288-597-02
- basic care nighttime severe cold and flu acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride 325 mg/15mL; 10 mg/15mL; 6.25 mg/15mL; 5 mg/15mL Solution NDC 72288-601-40
- Epsom Salt Magnesium Sulfate 1 g/g Granule, For Solution NDC 72288-602-04
- basic care daytime severe cold and flu acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride 325 mg/15mL; 10 mg/15mL; 200 mg/15mL; 5 mg/15mL Solution NDC 72288-603-34
- basic care ibuprofen 200 mg Tablet, Film Coated NDC 72288-604-78
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses ▪ temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold ▪ temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: ▪ runny nose ▪ sneezing ▪ itchy, watery eyes ▪ itching of the nose or throat ▪ controls the impulse to cough to help you sleep
⏱️ Dosage and Administration ▾
Directions ▪ measure only with dosing cup provided ▪ keep dosing cup with product ▪ mL = milliliter ▪ do not take more than 4 doses in any 24-hour period ▪ this adult product is not intended for use in children under 12 years of age age dose adults and children 12 years and over 20 ml every 6 hours children under 12 years do not use
⚠️ Warnings ▾
Warnings Do not use ▪ to sedate a child or to make a child sleepy ▪ if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have ▪ trouble urinating due to an enlarged prostate gland ▪ glaucoma ▪ a cough that occurs with too much phlegm (mucus) ▪ a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product ▪ do not use more than directed ▪ marked drowsiness may occur ▪ avoid alcoholic drinks ▪ alcohol, sedatives, and tranquilizers may increase drowsiness ▪ be careful when driving a motor vehicle or operating machinery ▪ excitability may occur, especially in children Stop use and ask a doctor if cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache.
These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.
In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222.
📦 Storage and Handling ▾
Other information ▪ each 20 ml contains: sodium 6 mg ▪ store at room temperature.
🧪 Active Ingredient ▾
Active ingredients (in each 20 ml) Purposes Dextromethorphan HBr, USP 30 mg Cough suppressant Doxylamine Succinate, USP 12.5 mg Antihistamine
🧪 Inactive Ingredients ▾
Inactive ingredients anhydrous citric acid, FD&C Red #40, flavor, menthol, propylene glycol, purified water, sodium benzoate, sorbitol, sucralose, xanthan gum.
🎯 Purpose ▾
Active ingredients (in each 20 ml) Purposes Dextromethorphan HBr, USP 30 mg Cough suppressant Doxylamine Succinate, USP 12.5 mg Antihistamine
📄 Do Not Use ▾
Do not use ▪ to sedate a child or to make a child sleepy ▪ if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
📄 Ask a Doctor Before Use If ▾
Ask a doctor before use if you have ▪ trouble urinating due to an enlarged prostate gland ▪ glaucoma ▪ a cough that occurs with too much phlegm (mucus) ▪ a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema
📄 Ask a Doctor or Pharmacist Before Use If ▾
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers
📄 When Using This Product ▾
When using this product ▪ do not use more than directed ▪ marked drowsiness may occur ▪ avoid alcoholic drinks ▪ alcohol, sedatives, and tranquilizers may increase drowsiness ▪ be careful when driving a motor vehicle or operating machinery ▪ excitability may occur, especially in children
📄 Stop Use and Ask a Doctor If ▾
Stop use and ask a doctor if cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition.
🤰 If Pregnant or Breast-Feeding ▾
If pregnant or breast-feeding, ask a health professional before use.
📄 Keep Out of Reach of Children ▾
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222.
📄 Questions or Comments ▾
Questions or comments? 1-866-467-2748
📄 Package Label / Principal Display Panel ▾
PRINCIPAL DISPLAY PANEL Compare to the active ingredients in Adult Robitussin ® Maximum Strength Nighttime Cough DM * NDC 72288-587-04 MAXIMUM STRENGTH Adult Nighttime Cough DM Dextromethorphan HBr (Cough Suppressant) Doxylamine Succinate (Antihistamine) • Controls Cough • Relieves Runny Nose & Sneezing For Ages 12 & Over 4 FL OZ (118 mL) Distributed by: IMPORTANT: Keep this carton for future reference for full labelling. TAMPER EVIDENT: DO NOT USE IF PRINTED SEAL UNDER CAP IS TORN OR MISSING. *This product is not manufactured or distributed by Haleon US Holding LLC, owner of the registered trademark Adult Robitussin ® Maximum Strength Nighttime Cough DM.
Amazon Maximum Strength adult nighttime cough DM 118mL
About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |