INSTA RELIEF DM LIDOCAINE HYDROCHLORIDE, MENTHOL 40 mg/mL; 10 mg/mL Cream, 118 mL
by DM LAB CORP · 118 mL in 1 JAR (72465-600-00)
NDC 72465-0600-00
🏷️ FDA NDC (as labeled)
72465-600-00
billing pads the product segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
72465-600-00
Product NDC
72465-600
11-digit billing NDC
72465060000
RxCUI
1595624
UNII
V13007Z41A, L7T10EIP3A
UPC
0860144002410
Application #
M017
SPL Set ID
6ef66fb9-9f49-409d-9503-175c7555ee9e
Established class (EPC)
Amide Local Anesthetic; Antiarrhythmic
Physiologic effect
Local Anesthesia
Chemical class
Amides
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2018-07-05
Route
TOPICAL
Dosage form
CREAM
Substance
LIDOCAINE HYDROCHLORIDE; MENTHOL
Why two NDCs?
The FDA registers this code as 72465-600-00 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 72465-0600-00. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Antiarrhythmic class.
Pharmacologic class
Antiarrhythmic, Amide Local Anesthetic
Drug family (ATC)
Antiarrhythmics, class Ib, Local anesthetics, Anesthetics for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerDM LAB CORP
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code72465
First marketedJul 2018
Product typeHuman Otc Drug
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
🧪 What is this product?
Insta Relief DM is a topical cream containing lidocaine hydrochloride and menthol. This is an over-the-counter monograph product, meaning it is marketed under FDA's established rules for this category of medicine. Lidocaine is a local anesthetic commonly used to numb skin and reduce pain sensation on the area where the cream is applied. Menthol, derived from peppermint oil, is typically used for its cooling sensation and is often included in topical pain-relief products to provide additional comfort and soothing effects.
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about LIDOCAINE HYDROCHLORIDE, MENTHOL?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Walgreens Cool n Heat 1 g/100g; 4 g/100g 00363-3036-02 | Walgreens | 1 bottle | — | — | FDA listed | — |
| Triderma Pain Relief 4 g/100g; 1 g/100g 10738-0073-20 | Genuine | 1 jar | — | — | FDA listed | — |
| Icy Hot with Lidocaine Pain Relieving .4 g/g; .1 g/g 41167-1710-00 | Chattem, | 1 tube | — | — | FDA listed | — |
| Meijer Cold and Hot Pain Relieving Analgesic 40 mg/g; 10 mg/g 41250-0355-01 | Meijer | 1 bottle | — | — | FDA listed | — |
| CVS Health Maximum Strength Lidocaine Pain Relief Cream Plus Menthol 40 mg/g; 10 mg/g 59779-0910-01 | CVS | 1 bottle | — | — | FDA listed | — |
| Pain Relief 1 mg/100mg; 4 mg/100mg 72042-0001-01 | HUMN | 1 tube | — | — | FDA listed | — |
| Workvie 1 g/100g; 4 g/100g 72393-0203-25 | Marketites | 71 g | — | — | FDA listed | — |
| Insta Relief Dm 40 mg/mL; 10 mg/mLthis 72465-0600-00 | DM | 118 ml | — | — | FDA listed | — |
| Bakers Best Maximum Strength Pain Relief 40 mg/g; 10 mg/g 76102-0031-02 | Baker's | 56.7 g | — | — | FDA listed | — |
| Zylotrol Pain Relieving 4 g/100g; 1 g/100g 76420-0560-04 | Asclemed | 102 g | — | — | FDA listed | — |
| SANTO REMEDIO Alivio Pain Relieving Lavender Scent 40 mg/mL; 10 mg/mL 81352-0519-00 | SANTO | 1 tube | — | — | FDA listed | — |
| Zylotrol Pain Relieving 4 g/100g; 1 g/100g 81902-0230-01 | Whitestone | 102 g | — | — | FDA listed | — |
| BlueStop Max 40 mg/g; 10 mg/g 82714-0002-01 | Clavel | 1 tube | — | — | FDA listed | — |
| Rapid Pain-Relief Topical 40 mg/mL; 10 mg/mL 82798-0295-02 | NORDIC | 60 ml | — | — | FDA listed | — |
| LidoSync 3.1 g/76.5g; .8 g/76.5g 82944-0200-01 | iON | 1 bottle | — | — | FDA listed | — |
| Nervive Pain Relieving Cream 4 g/100g; 1 g/100g 84126-0318-03 | The | 1 tube | — | — | FDA listed | — |
| Dermatool Nerve Care 1 g/100g; 4 g/100g 84728-0359-05 | Papalo | 1 bottle | — | — | FDA listed | — |
| 5Kind DMSO 4 Lidocaine HCl Pain Relieving 40 mg/mL; 10 mg/mL 85978-0929-00 | 5KIND | 118 ml | — | — | FDA listed | — |
| Lidozen 40 mg/mL; 10 mg/mL 71574-0300-72 | Village | 1 bottle | — | — | FDA listed | — |
| 5Kind Neurophase Pro Pain Relieving 40 mg/mL; 10 mg/mL 85978-0016-00 | 5KIND | 118 ml | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2018
On the market since
Jul 2018
📍
2026
Currently FDA-listed
8 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 72465-0600-00 You're viewing this | 118 mL in 1 JAR (72465-600-00) | 2018-07-05 | Active |
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | — Not published for this NDC No photo available yet for this listing. |
| Inactive ingredients (structured) | — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available. |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 72465-600-00, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 72465-0600-00, written without dashes as 72465060000. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 72465-0600-00, the first segment (72465) is the labeler code FDA assigned to DM LAB CORP; the middle segment (0600) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (00) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by DM LAB CORP. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
DM LAB CORP is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
INDICATIONS: For the temporary relief of pain and itching assoicated with minor burns sunburn, minor cuts, scrapes, insect bites or minor skin irritations.
⏱️ Dosage and Administration ▾
DIRECTIONS: Adults and children two-years of age or older: Apply to affected area not more than three to four times daily Children under two-years of age: consult a physician.
⚠️ Warnings ▾
WARNINGS For external use only. Avoid contact with eyes. If symptoms persist for more than seven days, discontinue use and consult physician. Keep out of reach of children. If swallowed, consult physician. Do not apply to wounds or damaged skin. Do not bandage tightly. If pregnant or breast feeding, contact physician
🧪 Active Ingredient ▾
ACTIVE INGREDIENTS Lidocaine HCL 4.00% Menthol 1.00% Topical Anesthetic
🧪 Inactive Ingredients ▾
OTHER INGREDIENTS: Aloe Barbadensis Leaf (Aloe Vera Gel) Juice, Aqua (Deionized Water), Benzyl Alchol, Caprylic/Capric Triglyceride, Carbomer, Cetearyl Alcohol, Cetereth-20, Cetyl Alcohol, Citrus Aurantifolia (Orange) Oil, Daucus Carota Sativa (Carrot) Extract, Ethylhexylglycerin, Eucalyptus Globulus Oil, Glycerin, 1-Arginine, Lavandula Angustifolia (Lavender) Oil, Lecithin, Methylsulfonylmethane (MSM), Phenoxyethanol, Potassium Hydroxide
🎯 Purpose ▾
Topical Anesthetic
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.