Hemorrohoid Master Cream Lidocaine, Phenylephrine Hcl 50 mg/g; 2.5 mg/g Cream, 45 g
🆔 Identity & classification
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🏷️ RxNorm drug class
This medicine belongs to the Antiarrhythmic class.
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🏭 Manufacturer & labeler
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🩺 Clinical
Hemorrhoid Master Cream is a topical cream marketed as an over-the-counter monograph product. It contains lidocaine, a local anesthetic typically used to numb and reduce discomfort in the area where applied, and phenylephrine hydrochloride, a decongestant commonly used to reduce swelling and shrink blood vessels in localized tissues. This combination is typically formulated for temporary relief of hemorrhoid-related symptoms.
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Supplement & herbal interactions
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💊 What it looks like
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🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
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UNII A7E6112E4N
A form of vitamin E used as an antioxidant in medicines. It prevents oils and fats in the product from breaking down, helping maintain stability and shelf life.
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A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.
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Aloe vera leaf juice is a clear gel extracted from aloe vera plant leaves. It's used in medicines as a lubricant, emollient, and preservative to soothe skin contact and help keep the product stable.
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Argan oil is a plant-derived oil from argan tree kernels. It's used in medicines as an emollient and skin-conditioning agent to help soften and moisturize the product's texture.
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Butylated hydroxyanisole is a synthetic preservative that prevents oils and fats in medicines from spoiling or becoming rancid. It keeps the medicine stable and extends its shelf life.
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BHT is a synthetic antioxidant that prevents fats and oils in medicines from breaking down and becoming rancid. It helps keep the product stable and effective during storage.
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A plant extract from calendula flowers, traditionally used in formulations. It typically serves as a botanical ingredient that may provide color, fragrance, or skin-conditioning properties to topical products.
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A plant extract from the Assam tea plant. It's used as a flavoring agent and antioxidant in formulations to enhance taste and help preserve the product.
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Caprylyl glycol is a clear liquid derived from coconut oil. In medicines, it acts as a humectant to retain moisture, a preservative booster to prevent microbial growth, and a solvent to help dissolve or mix other ingredients.
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A synthetic polymer that absorbs water and forms a thick, gel-like substance. In medicines, it works as a thickener and stabilizer to improve texture and help ingredients stay mixed together in creams, gels, and lotions.
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Safflower oil is a plant-based oil extracted from safflower seeds. It's used in medicines as a solvent and carrier to help dissolve or suspend active ingredients, and sometimes as an emollient to improve texture.
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Centella asiatica leaf is a plant extract used in medicines as a skin-conditioning agent and natural ingredient. It may help soften or soothe the product's texture and is included for its traditional botanical properties in topical or oral formulations.
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A waxy solid derived from plant or animal sources. It acts as an emulsifier to blend oil and water components, and also thickens the medicine to give it the right texture and consistency.
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Cetearyl glucoside is a plant-derived surfactant made from vegetable oils and glucose. It helps oils and water mix together in creams and lotions, and can also soften and smooth the skin feel of the product.
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Chamomile is a plant extract used in medications as a flavoring agent and for its mild soothing properties in formulations. It helps improve taste and aroma of the medicine.
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A weak organic acid derived from citrus fruits or made through fermentation. It works as a buffer to control pH, a preservative to extend shelf life, and a flavoring agent in medications.
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Coconut oil is a natural fat extracted from coconut fruit. It's used in medicines as a lubricant, emollient, or carrier to help dissolve or deliver active ingredients smoothly through the formulation.
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Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
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A chelating agent derived from ethylenediaminetetraacetic acid (EDTA) combined with copper. It binds metals in formulations to prevent discoloration and degradation, helping preserve the medicine's stability and appearance.
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Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
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Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
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A waxy substance made from glycerin and stearic acid. It works as an emulsifier to help mix oil and water ingredients together, and as a thickener to give the medicine its proper texture and consistency.
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Hexylene glycol is a clear liquid alcohol used as a solvent and preservative in medicines. It helps dissolve other ingredients and keeps the product stable during storage.
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A plant extract from horse chestnut seeds used in formulations as a natural thickening agent and binder. It helps hold tablet or capsule ingredients together and may improve product texture.
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A plant-derived thickening agent made from cellulose. It increases viscosity and helps form a gel or paste consistency in medications, and may serve as a binder or coating material in various formulations.
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Indian frankincense is a natural resin extracted from trees native to India. It is used in medicines as a binder and thickening agent to help hold ingredients together and improve texture.
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Isopropyl myristate is an oily liquid made from coconut or palm oil. It's used in medicines as an emollient and penetration enhancer to help the medicine absorb through skin or improve spreadability in topical products.
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A fragrant oil extracted from lavender plants, used as a flavoring and scent agent in medicines to improve taste and aroma.
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A fragrant essential oil derived from myrtle plant leaves. It's used in medicines as a flavoring agent and to mask unpleasant tastes, making the medication more pleasant to take.
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Panax ginseng root is a plant extract traditionally used in herbal preparations. In medications, it may serve as an active botanical ingredient or be included for flavoring and as a natural preservative or binder in formulations.
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Panthenol is a humectant and skin-conditioning agent derived from pantothenic acid. It's added to medicines to help retain moisture and soothe skin irritation.
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A waxy substance made from polyethylene glycol and stearic acid. It helps mix oil and water-based ingredients together and serves as an emulsifier and solubilizer in liquid and semi-solid medicines.
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Petrolatum is a purified mineral oil-based jelly derived from petroleum. In medicines, it acts as an emollient, lubricant, and moisture barrier to soften skin, reduce friction, and help prevent water loss from formulations.
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Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
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A natural plant extract from pomegranate fruit, used as a flavor and color ingredient to enhance taste and appearance in medicines.
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Pyridoxine hydrochloride is a form of vitamin B6, added to medicines as a nutritional supplement or to meet dietary requirements. It supports the body's metabolism and nerve function.
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Sodium citrate is a salt derived from citric acid. It works as a buffer to maintain the medicine's pH level and may also help improve taste or act as a preservative in the formulation.
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Sodium metabisulfite is a preservative derived from sulfur compounds. It prevents microbial growth and oxidation in medicines, helping extend shelf life and maintain product stability.
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Stearic acid is a fatty acid derived from plant or animal sources. It acts as a binder and lubricant in tablets and capsules, helping them hold together and flow smoothly during manufacturing.
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Trolamine is an alkaline compound used as a pH buffer and emulsifier in medicines. It helps neutralize acids, stabilize formulations, and enable mixing of oil and water-based ingredients.
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Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
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Witch hazel is a plant extract obtained from the leaves and bark of the North American shrub Hamamelis virginiana. It functions as an astringent and skin-conditioning agent in topical products, helping to tone and prepare the skin.
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Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.
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Zinc oxide is a white mineral powder used in medicines as a protective barrier agent and color additive. It helps shield skin in topical products and may also serve as a filler or opacifying ingredient.
44 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
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💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Liposomal Hemorrhoid Master 5 g/100g; .25 g/100g 63742-0038-01 | Clinical | 1 tube | — | — | FDA listed | — |
| Hemorrohoid Master Cream 50 mg/g; 2.5 mg/gthis 72654-0038-01 | Ebanel | 45 g | — | — | FDA listed | — |
| Hemorrhoid and Fissure Cream with Lidocaine 5% plus Phenylephrine HCL 0.25% 5 g/100g; .25 g/100g 73715-0007-01 | Mohnark | 30 g | — | — | Discontinued | — |
| tina davies IceCream Hemorrhoidal 5 g/100mL; .25 g/100mL 84313-0002-15 | TINA | 1 tube | — | — | FDA listed | — |
| tina davies IceJelly Hemorrhoidal 5 g/100mL; .25 g/100mL 84313-0101-30 | TINA | 1 tube | — | — | FDA listed | — |
| Treatonic hemorrhoid treatment 2.5 g/50g; .125 g/50g 85569-0008-01 | 100 | 50 g | — | — | Discontinued | — |
Where does this data come from?
⏳ Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 72654-0038-01 You're viewing this | 45 g in 1 TUBE, WITH APPLICATOR (72654-038-01) | 2025-06-06 | Active |
🧭 About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | — Not published for this NDC No photo available yet for this listing. |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
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📄 FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses ■ For the temporary relief of local and anorectal itching and discomfort associated with anorectal disorders and anorectal inflammation. ■ For the temporary relief of pain, burning and soreness. ■ Temporarily shrinks hemorrhoidal tissue. ■ Temporarily reduces the swelling associated with irritation in hemorrhoids and other anorectal disorders.
⏱️ Dosage and Administration ▾
Directions ■ Adults: When practical, cleanse the affected area with mild soap and warm water and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or a soft cloth before application of this product. Children under 12 years of age: consult a doctor. ■ For External Use: Apply externally to the affected area up to 4 times daily. ■ For Intrarectal use: Attach applicator to tube.
Lubricate applicator well, then gently insert applicator into the rectum. Apply to the affected area up to 4 times daily.
⚠️ Warnings ▾
Warnings: For external and / or intrarectal use only. ■ If condition worsens or does not improve within 7 days, consult a doctor. ■ Do not exceed the recommended daily dosage unless directed by a doctor. ■ In case of bleeding, consult a doctor promptly. ■ Certain persons can develop allergic reactions to ingredients in this product. If the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase, discontinue use and consult a doctor. ■ Do not use this product if you have heart disease, high blood pressure, thyroid disease, diabetes, or difficulty in urination due to enlargement of the prostate gland unless directed by a doctor. ■ Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression. ■ Do not use this product with an applicator if the introduction of the applicator into the rectum causes additional pain.
Consult a doctor promptly.
🧪 Active Ingredient ▾
Active Ingredients Lidocaine 5.00% Phenylephrine HCl 0.25%
🧪 Inactive Ingredients ▾
Inactive Ingredients Aesculus Hippocastanum (Horse Chestnut) Seed Extract, Alcohol, Aloe Barbadensis Leaf Juice, Argania Spinosa Kernel Oil, BHA, BHT, Boswellia Serrata Resin Extract, Calendula Officinalis Flower Extract, Camellia Sinensis Leaf Extract, Caprylyl Glycol, Carbomer, Carthamus Tinctorius (Safflower) Seed Oil, Centella Asiatica Extract, Cetearyl Alcohol, Cetearyl Glucoside, Chamomilla Recutita (Matricaria) Flower Extract, Citric Acid, Cocos Nucifera (Coconut) Oil, Dimethicone, Disodium EDTA, Ethylhexylglycerin, Glycerin, Glyceryl Stearate, Hamamelis Virginiana (Witch Hazel) Water, Hexylene Glycol, Hydroxyethylcellulose, Isopropyl Myristate, Lavandula Angustifolia (Lavender) Oil, Myrtus Communis Oil, Panax Ginseng Root Extract, Panthenol, PEG-100 Stearate, Petrolatum, Phenoxyethanol, Punica Granatum Fruit Extract, Pyridoxine HCl, Sodium Citrate, Sodium Metabisulfite, Stearic Acid, Tocopheryl Acetate, Triethanolamine, Water, Xanthan Gum, Zinc Oxide
🎯 Purpose ▾
Purpose Local Anesthetic Vasoconstrictor