Home › NDC Lookup › Ingredients › Homosalate, Octocrylene, Octisalate, Ens... › 74005-0002-02
Mediheal Madecassoside Moisture Sun Serum Homosalate, Octocrylene, Octisalate, Ensulizole 5 g/100mL; 2.5 g/100mL; 5 g/100mL; 4.5 g/100mL Lotion, 15 mL — NDC 74005-0002-02 package photo

Mediheal Madecassoside Moisture Sun Serum Homosalate, Octocrylene, Octisalate, Ensulizole 5 g/100mL; 2.5 g/100mL; 5 g/100mL; 4.5 g/100mL Lotion, 15 mL

by 74005 · 1 CONTAINER in 1 BOX (74005-002-02) / 15 mL in 1 CONTAINER
NDC 74005-0002-02
🏷️ FDA NDC (as labeled) 74005-002-02 billing pads the product segment with a zero
This package
Contains15 mL Pack sizes4 compare ↓
Also comes in: 50 ml 74005-0002-01 50 ml 74005-0002-03 115 ml 74005-0002-04
OTC On market Non-controlled
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 74005-002-02
Product NDC 74005-002
11-digit billing NDC 74005000202
UNII V06SV4M95S, 9YQ9DI1W42, 5A68WGF6WM, 4X49Y0596W
Application # M020
SPL Set ID 47c66535-8287-9b74-e063-6394a90ac3b6
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2026-05-01
Route TOPICAL
Dosage form LOTION
Substance HOMOSALATE; ENSULIZOLE; OCTOCRYLENE; OCTISALATE
Why two NDCs? The FDA registers this code as 74005-002-02 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 74005-0002-02. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

Labeler74005
FDA applicationM020 (OTC MONOGRAPH DRUG)
Labeler code74005
First marketedMay 2026
Product typeHuman Otc Drug
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is a topical lotion sunscreen marketed as an over-the-counter monograph product. It contains four UV-filtering compounds (homosalate, octisalate, octocrylene, and ensulizole) that are typically used together to absorb ultraviolet radiation and help protect skin from sun exposure. The product is applied to the skin and left on rather than rinsed off, functioning as a broad-spectrum sunscreen lotion.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color white
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII TR046Y3K1G
    A liquid alcohol derived from petroleum or plant sources. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
  • UNII LU49E6626Q
    A synthetic organic compound used as a pH buffer and neutralizing agent in medicines. It helps maintain the proper acidity level in liquid formulations to improve stability and comfort.
  • UNII 9PA5A687X5
    Asiatic acid is a natural compound extracted from plants that acts as an emollient and skin-conditioning agent in topical formulations. It helps soften and smooth the product's texture while supporting skin hydration.
  • UNII PKO39VY215
    A natural compound derived from Centella asiatica plant, used as an active botanical extract or skin-conditioning agent in topical formulations to support ingredient stability and product efficacy.
  • UNII 9G1OE216XY
    Docosanol is a waxy, fatty alcohol derived from plant sources. It acts as an emollient and thickener in topical medicines, helping to soften the skin and improve product texture and stability.
  • UNII 298PX4M11X
    A synthetic chemical compound that acts as an antioxidant, helping protect the medicine's active ingredients from degradation caused by light, heat, and oxygen during storage and shelf life.
  • UNII BB4PU4V09H
    A plant-derived gum that acts as a thickener and stabilizer in medications. It helps maintain consistent texture and prevents ingredient separation in liquid or semi-solid formulations.
  • UNII 3XUS85K0RA
    Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
  • UNII 2EH13UN8D3
    A synthetic compound used as a solvent and penetration enhancer in topical formulations. It helps dissolve active ingredients and allows them to penetrate the skin more effectively.
  • UNII E107L85C40
    Dipropylene glycol is a clear liquid made from propylene glycol. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
  • UNII S3KFG6Q5X8
    An organic chemical compound used as a UV filter in topical formulations. It helps protect the medicine or product from degradation caused by sunlight exposure during storage and use.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII MBQ7DDQ7AR
    Hydroxyethyl urea is a synthetic organic compound used in medicines as a humectant and conditioning agent. It helps retain moisture in formulations and may improve texture or stability in topical products.
  • UNII A8289P68Y2
    Isododecane is a lightweight liquid hydrocarbon used as a solvent and spreadability agent in topical formulations. It helps dissolve active ingredients and makes the product easier to apply and absorb into the skin.
  • UNII M7O1N24J82
    Madecassic acid is a natural compound extracted from Centella asiatica plant. In medications, it acts as an active pharmaceutical ingredient or functional excipient that may support skin health and wound healing in topical formulations.
  • UNII CQ2F5O6YIY
    A natural compound extracted from Centella asiatica plant used as an active skin-conditioning ingredient. It functions as a humectant and skin protectant to improve moisture retention and support skin barrier function in topical formulations.
  • UNII N8F53B3R4R
    A synthetic humectant and solvent derived from propane. It draws and holds moisture in the formulation, helping keep the medicine stable and improving texture or flow in liquid and semi-solid products.
  • UNII 25X51I8RD4
    Niacinamide is a form of vitamin B3, a water-soluble nutrient. In medicines, it may be added as a nutritional supplement or to support skin health, though its primary role here is as an active ingredient rather than a traditional inactive filler.
  • UNII 50C1307PZG
    Pentylene glycol is a humectant and preservative helper derived from petroleum or plant sources. It draws moisture into the product and helps prevent bacterial growth, keeping medicines stable during storage.
  • UNII W19EIO0DBE
    A plant-derived emulsifier made from glycerin and fatty acids. It helps mix oil and water-based ingredients together and stabilizes the product's texture in creams, lotions, and other cosmetic or topical formulations.
  • UNII 59Z907ZB69
    A synthetic silicone polymer used as a glidant and anti-caking agent. It reduces friction between particles, helping powders and tablets flow smoothly during manufacturing and use.
  • UNII 5965N8W85T
    Propanediol is a clear liquid organic compound derived from vegetable sources or synthesized chemically. It acts as a humectant to retain moisture, a solvent to dissolve active ingredients, and a preservative booster in liquid medications and supplements.
  • UNII YSE9PPT4TH
    Hyaluronate sodium is a natural carbohydrate that holds moisture. It's used in medicines as a lubricant, thickener, and moisture-retaining agent to improve texture and delivery of the active ingredient.
  • UNII 65A9F4P024
    A synthetic compound derived from the amino acid glutamate and stearic acid. It acts as an emulsifier and surfactant to help mix oil and water-based ingredients, keeping the medicine uniform throughout.
  • UNII R0ZB2556P8
    Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
  • UNII 3C8845E7C1
    Tripropylene glycol is a clear liquid made from propylene oxide. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and maintain moisture in the formulation.
  • UNII 023C2WHX2V
    Tromethamine is a chemical buffer that helps maintain the proper acidity level in liquid medicines. It neutralizes acids and stabilizes the solution so the medication remains effective and safe throughout its shelf life.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

28 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesWater, Butyloctyl Salicylate, Benzotriazolyl Dodecyl p-Cresol, Propanediol, Ethylhexyl Methoxycrylene, Methyl Methacrylate Crosspolymer, Niacinamide, Polymethylsilsesquioxane, Lauryl Dimethicone, Pentylene Glycol, 1,2-Hexanediol, Hydroxyethyl Urea, Aminomethyl Propanol, C11-13 Isoalkane, Isododecane, Butylene Glycol, Methylpropanediol, Behenyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Tripropylene Glycol, Vinyl Dimethicone, Dipropylene Glycol, Dimethiconol, Poly C10-30 Alkyl Acrylate, Polyacrylic Acid, Dimethicone/Vinyl Dimethicone Crosspolymer, Tromethamine, Polyether-1, Fragrance (Parfum), Ethylhexylglycerin, Sodium Stearoyl Glutamate, Sphingomonas Ferment Extract, Centella Asiatica Leaf Extract, Madecassoside, Sodium Hyaluronate, Biosaccharide Gum-1, Centella Asiatica Extract, Tocopherol, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Madecassic Acid, Asiatic Acid, Asiaticoside

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 50 ml 50 ml 115 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Mediheal Madecassoside Moisture Sun Serum 5 g/100mL; 2.5 g/100mL; 5 g/100mL; 4.5 g/100mLthis 74005-0002-02 74005 15 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2026
On the market since
May 2026
📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
74005-0002-01 1 CONTAINER in 1 BOX (74005-002-01) / 50 mL in 1 CONTAINER 2026-05-01 Active
74005-0002-02 You're viewing this 1 CONTAINER in 1 BOX (74005-002-02) / 15 mL in 1 CONTAINER 2026-05-01 Active
74005-0002-03 2 CONTAINER in 1 BOX (74005-002-03) / 50 mL in 1 CONTAINER 2026-08-10 Active
74005-0002-04 3 CONTAINER in 1 BOX (74005-002-04) / 115 mL in 1 CONTAINER 2026-08-10 Active

Pack size FAQ

What quantity is in NDC 74005-0002-02?
NDC 74005-0002-02 contains 15 mL — 1 container in 1 box / 15 ml in 1 container.
What is the difference between NDC 74005-0002-02 and NDC 74005-0002-01?
Both are Mediheal Madecassoside Moisture Sun Serum Homosalate, Octocrylene, Octisalate, Ensulizole 5 g/100mL; 2.5 g/100mL; 5 g/100mL; 4.5 g/100mL Lotion — the drug itself is identical. NDC 74005-0002-02 is the 15 mL package, while NDC 74005-0002-01 is the 50 ml package.
What NDC number is used to bill for this package of Mediheal Madecassoside Moisture Sun Serum Homosalate, Octocrylene, Octisalate, Ensulizole 5 g/100mL; 2.5 g/100mL; 5 g/100mL; 4.5 g/100mL Lotion?
Bill NDC 74005-0002-02 — the 11-digit billing format is 74005000202. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 74005-002-02, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 74005-0002-02, written without dashes as 74005000202. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 74005-0002-02, the first segment (74005) is the labeler code FDA assigned to 74005; the middle segment (0002) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (02) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by 74005. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 3 other package presentations of this same product, including 50 ml (74005-0002-01), 50 ml (74005-0002-03), 115 ml (74005-0002-04). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
74005 is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 31 words ▾

Uses ■ Helps prevent sunburn. ■ If used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun.

⏱️ Dosage and Administration 99 words ▾

Directions Directions ■ Apply liberally 15 minutes before sun exposure. ■ Reapply at least every 2 hours. ■ Use a water-resistant sunscreen if swimming or sweating. Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging.

To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: ■ Limit time in the sun, especially from 10 a.m. – 2 p.m. ■ Wear long-sleeved shirts, pants, hats, and sunglasses. ■ Children under 6 months of age: Ask a doctor.

⚠️ Warnings 60 words ▾

Warnings Warnings For external use only. Do not use ■ on damaged or broken skin. When using this product ■ keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if ■ rash occurs. Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

🧪 Inactive Ingredients 89 words ▾

Inactive Ingredients Water, Butyloctyl Salicylate, Benzotriazolyl Dodecyl p-Cresol, Propanediol, Ethylhexyl Methoxycrylene, Methyl Methacrylate Crosspolymer, Niacinamide, Polymethylsilsesquioxane, Lauryl Dimethicone, Pentylene Glycol, 1,2-Hexanediol, Hydroxyethyl Urea, Aminomethyl Propanol, C11-13 Isoalkane, Isododecane, Butylene Glycol, Methylpropanediol, Behenyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Tripropylene Glycol, Vinyl Dimethicone, Dipropylene Glycol, Dimethiconol, Poly C10-30 Alkyl Acrylate, Polyacrylic Acid, Dimethicone/Vinyl Dimethicone Crosspolymer, Tromethamine, Polyether-1, Fragrance (Parfum), Ethylhexylglycerin, Sodium Stearoyl Glutamate, Sphingomonas Ferment Extract, Centella Asiatica Leaf Extract, Madecassoside, Sodium Hyaluronate, Biosaccharide Gum-1, Centella Asiatica Extract, Tocopherol, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Madecassic Acid, Asiatic Acid, Asiaticoside

🎯 Purpose 2 words ▾

Purpose Sunscreen

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 73978-0009-01 · Marque 74028-0149-01 · Creative →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.