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Drs. ACNE SPOT TREATMENT SALICYLIC ACID 20 mg/g Gel — NDC 80489-357-01 (Billing 80489-0357-01)

by OL PHARMA TECH, LLC Drs. PHARMACY · 1 TUBE, WITH APPLICATOR in 1 CARTON / 20 g in 1 TUBE, WITH APPLICATOR

This is a package of Drs. ACNE SPOT TREATMENT SALICYLIC ACID 20 mg/g Gel from OL PHARMA TECH, LLC Drs. PHARMACY, marketed since Feb 2022 and currently FDA-listed. It is the main listing for this product, which comes in 2 package sizes.

NDC 80489-0357-01
🏷️ FDA NDC (as labeled) 80489-357-01 billing pads the product segment with a zero
This package
Contains20 g in 1 tube, with applicator Pack sizes2 compare ↓
Main listing for product 80489-357 · Also comes in: 30 g 80489-357-02
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 80489-357-01 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
80489 labeler · 357 product · 01 package
Package marketed since
Apr 13, 2024
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Barcode (UPC-A, from the NDC)
3 8048935701 8
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 80489-357-01
Product NDC 80489-357
11-digit billing NDC 80489035701
RxCUI 346298
UNII O414PZ4LPZ
Application # M006
SPL Set ID 161b2306-364a-e1b8-e063-6394a90a6c88
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2022-02-01
Route TOPICAL
Dosage form GEL
Substance SALICYLIC ACID
Quick answers
  • RxCUI (RxNorm): 346298
Why two NDCs? The FDA registers this code as 80489-357-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 80489-0357-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Salicylic acid and derivatives class.

Drug family (ATC) Salicylic acid and derivatives, Other antifungals for topical use, Antiinflammatory agents, non-steroids
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

🧪 What is this product?

This is an over-the-counter topical gel containing salicylic acid, marketed under FDA's established rules for acne spot treatments. Salicylic acid is a common ingredient typically used to help clear and prevent acne blemishes by working to soften and loosen dead skin cells on the skin's surface. The product is applied directly to affected areas of the skin as a spot treatment.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 30 g
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
80489-0357-01 You're viewing this Main listing 1 TUBE, WITH APPLICATOR in 1 CARTON / 20 g in 1 TUBE, WITH APPLICATOR 2024-04-13 — Active
80489-0357-02 80489-357-02 1 TUBE, WITH APPLICATOR in 1 CARTON / 30 g in 1 TUBE, WITH APPLICATOR 2024-04-13 — Active

Pack size FAQ

What quantity is in this package?
This package is listed by the FDA — 1 tube, with applicator in 1 carton / 20 g in 1 tube, with applicator.
What NDC number is used to bill for this package of Drs. ACNE SPOT TREATMENT SALICYLIC ACID 20 mg/g Gel?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Sulfur 8 Fresh Anti-Dandruff Hair and Scalp Conditioner 20 mg/g 12022-0026-00 J. 108 g — — FDA listed —
CeraVe Developed with Dermatologists Psoriasis Moisturizing 20 mg/g 49967-0701-01 L'Oreal 227 g — — FDA listed —
111MedCo 2% Salicylic Acid Cleansing Bar 20 mg/g 72811-0000-04 111MedCo 113 g — — FDA listed —
Equate Beauty Medicated Apricot Cleanser Acne Medication 20 mg/g 79903-0323-06 WALMART 170 g — — FDA listed —
Medicated Apricot Scrub 20 mg/g 49035-0003-30 Walmart 170 g — — FDA listed —
Medicated Apricot Scrub 20 mg/g 55910-0034-30 Old 170 g — — FDA listed —
Medicated Apricot Scrub 20 mg/g 56062-0003-30 Publix 170 g — — FDA listed —
DermaD ATOPIC DERMATITIS Therapeutic 20 mg/g 70794-0101-28 Chen 81 g — — FDA listed —
Medicated Apricot Scrub 20 mg/g 41163-0041-30 United 170 g — — FDA listed —
Meijer Blackhead Clearing Scrub Acne medication 20 mg/g 41250-0879-01 Meijer 141 g — — FDA listed —
DermaER Psoriasis Therapeutic 20 mg/g 70794-0207-14 Chen 50 g — — FDA listed —
DermaD Psoriasis Therapeutic 20 mg/g 70794-0261-25 Chen 81 g — — FDA listed —
DermaD ANTIFUNGAL Therapeutic 20 mg/g 70794-0708-85 Chen 81 g — — FDA listed —
Clean and Clear acne triple clear exfoliating scrub 20 mg/g 69968-0013-05 Kenvue 141 g — — FDA listed —
Neutrogena Oil-Free Acne Wash Cream Cleanser 20 mg/g 69968-0940-06 Kenvue 189 g — — FDA listed —
Medicated Apricot Scrub 20 mg/g 72476-0044-30 Retail 170 g — — FDA listed —
Blackhead Clearing Scrug 20 mg/g 49035-0301-56 Walmart 141 g — — FDA listed —
pHisoderm Clear Confidence Face Scrub 20 mg/g 10742-1233-01 The 142 g — — FDA listed —
Asepxia Acne Treatment 20 mg/g 50066-0064-01 Genomma 1 tube — — FDA listed —
DermaD JOCK ITCH Therapeutic 20 mg/g 70794-0201-82 Chen 81 g — — FDA listed —
pHisoderm CLEAN ANTI-BLEMISH BODY WASH 20 mg/g 10742-1236-01 The 5 g — — FDA listed —
Medicated Apricot Scrub 20 mg/g 36800-0009-30 Topco 170 g — — FDA listed —
Dermaclear Mask 20 mg/g 62742-4074-02 Allure 1 tube — — FDA listed —
Neutrogena Oil-Free Acne Stress Control Power-Cream Wash 20 mg/g 69968-0941-06 Kenvue 172 g — — FDA listed —
DermaD ANTI-ITCH Therapeutic 20 mg/g 70794-0313-94 Chen 81 g — — FDA listed —
Viaderma Clear Acne Treatment 20 mg/g 71262-0016-15 ViaDerma 1 bottle — — FDA listed —
OXY Volcanic Clay Acne Wash 20 mg/g 10742-8338-01 The 142 g — — FDA listed —
Natureplex Psoriasis 20 mg/g 67234-0073-01 Natureplex, 1 tube — — FDA listed —
amazon basics acne blackhead clearing scrub Acne Treatment 20 mg/g 72288-0862-01 AMAZON.COM 142 g — — FDA listed —
ULTA All Clear SERUM 20 mg/g 79959-0011-01 APR 1 tube — — FDA listed —
Phisoderm Anti-Blemish Gel Cleanser 20 mg/g 10742-8417-01 The 177 g — — FDA listed —
PanOxyl 20 mg/g 00316-0288-01 Crown 113 g — — FDA listed —
Medicated Apricot Scrub 20 mg/g 41250-0007-30 Meijer, 170 g — — FDA listed —
Clean and Clear blackhead eraser scrub 20 mg/g 69968-0234-05 Kenvue 141 g — — FDA listed —
Clean and Clear Acne Spot Treatment 20 mg/g 69968-1016-01 Kenvue 1 tube — — FDA listed —
Drs. ACNE SPOT TREATMENT 20 mg/gthis 80489-0357-01 OL 1 tube — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2022
On the market since
Feb 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerOL PHARMA TECH, LLC Drs. PHARMACY
FDA applicationM006 (OTC MONOGRAPH DRUG)
Labeler code80489
First marketedFeb 2022
Product typeHuman Otc Drug
Portfolio2 products on file

More NDCs from OL PHARMA TECH, LLC Drs. PHARMACY labeler code 80489

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 When Using This Product 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 19 words ▾

USES For the treatment of acne. Dries and clears acne pimples, blackheads and whiteheads and allows skin to heal.

⏱️ Dosage and Administration 34 words ▾

DIRECTIONS Morning and evening, after a thorough cleansing of the skin, apply acne clear gel locally on cutanous imperfections. Then apply the usual day or night cream. Renew application 1 to 3 times daily.

⚠️ Warnings 74 words ▾

WARNINGS For external use only . Using other topical acne medications at the same time or immediately following use of this product may increase dryness or irritation of the skin. If this occurs, only one medication should be used unless directed by a doctor. Avoid direct contact with the eyes. If product gets into the eyes, rinse liberally with water. Discontinue use if skin irritation develops or increases. If irritation persists, consult a doctor.

📦 Storage and Handling 18 words ▾

OTHER INFORMATION store at 15-30 C ( 59-86 F) close cap tightly after use keep away from heat

🧪 Active Ingredient 6 words ▾

ACTIVE INGREDIENT Salicylic Acid 2% w/w.

🧪 Inactive Ingredients 19 words ▾

carbomer interpolymer type A, trolamine, vitamin E, propylene glycol, water, isopropyl alcohol, methyl paraben, EDTA, propyl paraben, DMDM hydantoin

🎯 Purpose 3 words ▾

PURPOSE Acne treatment

📄 Do Not Use 14 words ▾

DO NOT USE if you have sensitive skin or are sensitive to salicylic acid

📄 When Using This Product 11 words ▾

WHEN USING THIS PRODUCT Avoid contact with eyes, lips, and mouth.

📄 Keep Out of Reach of Children 18 words ▾

KEEP OUT OF REACH OF CHILDREN if swallowed, get medical help or contact poison control center right away

📄 Questions or Comments 2 words ▾

QUESTIONS www.drspharmacyusa.com

📄 Package Label / Principal Display Panel 5 words ▾

PACKAGE LABEL ACNE SPOT TREATMENT

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Salicylic Acid (matched by generic name) — the program that covers self-administered drugs. 2 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Salicylic Acid. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$11.2K
Claims incl. refills
43
Beneficiaries
35
Spend / beneficiary
$319.01
Spend / claim
$259.66
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by OL PHARMA TECH, LLC Drs. PHARMACY. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 1 tube (80489-0357-02). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
OL PHARMA TECH, LLC Drs. PHARMACY is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 80489-0333-01 · OL 80489-0412-01 · OL →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.