Caring Mill Acne Clearing Cleanser SALICYLIC ACID .5 g/100mL Liquid, 250 mL
by FSA Store Inc. (Caring Mills) · 250 mL in 1 BOTTLE (81522-100-01)
NDC 81522-0100-01
🏷️ FDA NDC (as labeled)
81522-100-01
billing pads the product segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
81522-100-01
Product NDC
81522-100
11-digit billing NDC
81522010001
RxCUI
865105
UNII
O414PZ4LPZ
Application #
M006
SPL Set ID
4038bf3f-d6b9-48a2-e063-6394a90aea6b
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2025-10-03
Route
TOPICAL
Dosage form
LIQUID
Substance
SALICYLIC ACID
Why two NDCs?
The FDA registers this code as 81522-100-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 81522-0100-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Salicylic acid and derivatives class.
Drug family (ATC)
Salicylic acid and derivatives, Other antifungals for topical use, Antiinflammatory agents, non-steroids
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerFSA Store Inc. (Caring Mills)
FDA applicationM006 (OTC MONOGRAPH DRUG)
Labeler code81522
First marketedOct 2025
Product typeHuman Otc Drug
Portfolio16 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
📖 What it is MedlinePlus · NLM
Topical salicylic acid is used to help clear and prevent pimples and skin blemishes in people who have acne. Topical salicylic acid is also used to treat skin conditions that involve scaling or overgrowth of skin cells such as psoriasis (a skin disease in which red, scaly patches form on some areas of the body), ichthyoses (inborn conditions that cause skin dryness and scaling), dandruff, corns, calluses, and warts on the hands or feet. Topical salicylic acid should not be used to treat genital warts, warts on the face, warts with hair growing from them, warts in the nose or mouth, moles, or b...
Read the full MedlinePlus article ↗📗 Our plain-language guide HelloPharmacist
- It's designed to treat acne. Salicylic acid helps by loosening and removing dead skin cells that clog pores — the buildup that leads to breakouts. The multi-step system on this lab...
- What is this salicylic acid product actually supposed to do for my skin?
- Some mild tingling, stinging, and peeling is actually expected — that's the salicylic acid doing its job by clearing away dead skin cells. But if the burning or peeling feels exces...
- My skin feels like it's burning and peeling. Is that normal?
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about SALICYLIC ACID?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII 79G1T427CF
A foaming and cleansing agent derived from coconut oil. It's used in topical products as a thickener and to help create lather or improve how the formula spreads on skin.
-
UNII 147D247K3P
Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
-
UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
-
UNII VPE363894V
A mild, plant-derived cleaning agent used as a surfactant and foaming agent. It helps distribute active ingredients evenly throughout the product and creates a pleasant lather in topical formulations like shampoos and cleansers.
-
UNII 8L4OOQ76AM
A waxy compound made from polyethylene glycol and stearic acid that acts as an emulsifier and thickener. It helps blend oil and water-based ingredients together and gives the medicine its proper texture and consistency.
-
UNII HIE492ZZ3T
Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
-
UNII O9W3D3YF5U
A synthetic surfactant derived from petroleum-based olefins. It helps dissolve or suspend active ingredients and other substances in liquid formulations, improving how the medicine mixes and flows.
-
UNII 451W47IQ8X
Sodium chloride is common table salt. It's used in medicines as a buffer to maintain proper pH, as a filler to add bulk, or to adjust the osmotic balance in liquid formulations.
-
UNII W81N5U6R6U
Sodium glutamate is a salt form of glutamic acid, a naturally occurring amino acid. It serves as a flavor enhancer and pH buffer in medications, helping to improve taste and maintain chemical stability.
-
UNII 632GS99618
Sodium lauroyl sarcosinate is a mild, plant-derived cleaning agent used in medicines as a surfactant and emulsifier. It helps mix oil and water-based ingredients and may aid tablet disintegration.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
11 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesWATER SODIUM LAUROYL SARCOSINATE SODIUM GLUTAMATE LAURAMIDOPROPYL HYDROXYSULTAINE SODIUM CHLORIDE SODIUM C14-16 OLEFIN SULFONATE COCAMIDE METHYL MEA GLYCERIN SODIUM CHLORIDE PHENOXYETHANOL PEG-150 PENTAERYTHRITYL TETRASTEARATE ETHYLHEXYLGLYCERIN
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Ultra Clear Foaming Cleanser .5 g/100mL 10028-0050-01 | ULTRACEUTICALS | 150 ml | — | — | FDA listed | — |
| UNBLEMISH Refining Acne Wash .005 g/mL 14222-2111-01 | Rodan | 1 tube | — | — | FDA listed | — |
| Meijer Foaming Cleanser Acne medication 5 mg/mL 41250-0354-01 | Meijer | 177 ml | — | — | FDA listed | — |
| Deep Cleaning Astringent 5 mg/mL 41250-0775-34 | Meijer, | 237 ml | — | — | Discontinued | — |
| Vichy Laboratoires Normaderm Daily Gentle Cleanser 5 mg/mL 49967-0232-01 | L'Oreal | 125 ml | — | — | FDA listed | — |
| Vichy Laboratoires Normaderm Phytoaction Daily Deep Cleansing 5 mg/mL 49967-0307-01 | L'Oreal | 200 ml | — | — | FDA listed | — |
| Vichy Laboratoires Normaderm Daily Deep Cleansing Acne Treatment 5 mg/mL 49967-0630-01 | L'Oreal | 200 ml | — | — | FDA listed | — |
| Salicylic Acid Cleanser 5 mg/mL 54111-0171-02 | Bentley | 1 tube | — | — | FDA listed | — |
| Purifying Clay Mask .5 g/100mL 56152-5012-01 | Cosmetic | 88 ml | — | — | FDA listed | — |
| ageLOC LumiSpa Treatment Cleanser Acne 5 mg/mL 62839-1495-01 | NSE | 100 ml | — | — | FDA listed | — |
| Clear Smart Charcoal Blackhead Scrub .5 g/100mL 68828-0001-01 | Distribuidora | 1 tube | — | — | FDA listed | — |
| Cln Acne Cleanser 5 mg/mL 69530-0857-46 | TopMD | 100 ml | — | — | FDA listed | — |
| Vichy Laboratoires Normaderm Phytoaction Deep Cleansing 5 mg/mL 69625-0306-01 | COSMETIQUE | 200 ml | — | — | FDA listed | — |
| Vichy Laboratoires Normaderm Daily Deep Cleansing Acne Treatment 5 mg/mL 69625-0630-01 | COSMETIQUE | 200 ml | — | — | FDA listed | — |
| Skinpharmacy Advanced Acne Therapy Pore Refining Facial Mask 5 mg/mL 69842-0077-01 | CVS | 1 tube | — | — | FDA listed | — |
| Aveeno CLEAR COMPLEXION foaming cleanser 5 mg/mL 69968-0471-06 | Kenvue | 177 ml | — | — | FDA listed | — |
| Neutrogena deep clean purifying cooling gel scrub 5 mg/g 69968-0740-04 | Kenvue | 119 g | — | — | FDA listed | — |
| Aveeno Positively Radiant Clear Complexion Foaming Cleanser 5 mg/mL 69968-0769-06 | Kenvue | 177 ml | — | — | FDA listed | — |
| Clarifying Cleanser .5 g/100mL 70381-0128-02 | Murad, | 1 tube | — | — | FDA listed | — |
| So Totally Clean Deep Pore Cleanser .5 g/100mL 70626-0104-21 | ASPIRE | 200 ml | — | — | FDA listed | — |
| Clean Getaway Bag 70626-0504-54 | ASPIRE | 1 kit | — | — | FDA listed | — |
| MDacne Customized Acne Cleanser Hydrating Salicylic Acid 5 mg/mL 71804-0534-00 | MDAlgorithms | 59 ml | — | — | FDA listed | — |
| Salicylic Acid Cleanser 5 mg/g 73318-7001-02 | Skin | 1 bottle | — | — | FDA listed | — |
| Even and Clear Cleanser 5 mg/mL 73453-0003-01 | Ambi | 177 ml | — | — | FDA listed | — |
| Peach and Lily Peaches Slices Acne Oil Acne Free Moisturizer 5 mg/mL 81515-0502-01 | Peach | 80 ml | — | — | FDA listed | — |
| Caring Mill Acne Clearing Cleanser .5 g/100mLthis 81522-0100-01 | FSA | 250 ml | — | — | FDA listed | — |
| Derma Pella Acne Wash for Oily Skin 5 mg/mL 82160-0764-01 | Pella | 150 ml | — | — | Discontinued | — |
| Creamy Foam Cleanser .5 g/100mL 82870-0002-01 | Dime | 120 ml | — | — | FDA listed | — |
| Freshiny Facial Cleanser Acne Treatment 5 mg/g 84544-0001-01 | Guangdong | 1 tube | — | — | FDA listed | — |
| In the Clear Acne Serum .5 g/100mL 69366-0414-31 | The | 1 bottle | — | — | FDA listed | — |
| Clear Smart Clarifying Cleansing Foam .5 g/100mL 68828-0244-01 | Distribuidora | 125 ml | — | — | FDA listed | — |
| Stridex Sensitive .5 g/100mL 10157-1007-01 | Blistex | 1 jar | — | — | FDA listed | — |
| Clear Smart Clear Complexion Toner .5 g/100mL 68828-0289-01 | Distribuidora | 200 ml | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2025
On the market since
Oct 2025
📍
2026
Currently FDA-listed
1 year listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
📊 Medicare Part D spend CMS · PART D · 2026 (Q1)
Medicare Part D (outpatient prescription) spending for Salicylic Acid (matched by generic name) — the program that covers self-administered drugs. 2 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Salicylic Acid. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$11.2K
Claims incl. refills
43
Beneficiaries
35
Spend / beneficiary
$319.01
Spend / claim
$259.66
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Caring Mill Acne Clearing Cleanser (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 37%
Female · 63%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 81522-0100-01 You're viewing this | 250 mL in 1 BOTTLE (81522-100-01) | 2025-10-03 | Active |
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 81522-100-01, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 81522-0100-01, written without dashes as 81522010001. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 81522-0100-01, the first segment (81522) is the labeler code FDA assigned to FSA Store Inc. (Caring Mills); the middle segment (0100) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by FSA Store Inc. (Caring Mills). Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
FSA Store Inc. (Caring Mills) is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Dispense a small amount into hand and mix with a little water. Apply a thin layer over the entire affected area in a circular motion and rinse thoroughly with warm water two times daily. Because excessive dry of the skin may occur, start with one application daily, then gradually increase to two times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day.
⏱️ Dosage and Administration ▾
Wet the skin and gently massage for 1-2 minutes and rinse well. If bothersome dryness or peeling occurs, reduce frequency of use.
⚠️ Warnings ▾
For external use only. When using this product Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. When using this product If swallowed, get medical help or contact a Poison Control Center right away.
🧪 Active Ingredient ▾
SALICYLIC ACID： 0.5%
🧪 Inactive Ingredients ▾
WATER SODIUM LAUROYL SARCOSINATE SODIUM GLUTAMATE LAURAMIDOPROPYL HYDROXYSULTAINE SODIUM CHLORIDE SODIUM C14-16 OLEFIN SULFONATE COCAMIDE METHYL MEA GLYCERIN SODIUM CHLORIDE PHENOXYETHANOL PEG-150 PENTAERYTHRITYL TETRASTEARATE ETHYLHEXYLGLYCERIN
🎯 Purpose ▾
Acne Medication
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.