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Head and Shoulders Scalp Restore Nourishing Conditioner Pyrithione Zinc .5 g/100mL Lotion, 315 mL — NDC 84126-0906-31 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Head and Shoulders Scalp Restore Nourishing Conditioner Pyrithione Zinc .5 g/100mL Lotion, 315 mL — NDC 84126-906-31 (Billing 84126-0906-31)

by The Procter & Gamble Manufacturing Company · 315 mL in 1 TUBE

This is a package of 315 mL of Head and Shoulders Scalp Restore Nourishing Conditioner Pyrithione Zinc .5 g/100mL Lotion from The Procter & Gamble Manufacturing Company, marketed since Sep 2026 and currently FDA-listed. It is this product's only package size.

NDC 84126-0906-31
🏷️ FDA NDC (as labeled) 84126-906-31 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Sep 17, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 84126-906-31
Product NDC 84126-906
11-digit billing NDC 84126090631
RxCUI 1043014
UNII R953O2RHZ5
UPC 0030772284674
Application # M032
SPL Set ID 5a834d00-cc79-1a8e-e063-6294a90ab245
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2026-09-01
Route TOPICAL
Dosage form LOTION
Substance PYRITHIONE ZINC
Quick answers
  • RxCUI (RxNorm): 1043014
Why two NDCs? The FDA registers this code as 84126-906-31 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 84126-0906-31. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Other dermatologicals class.

Drug family (ATC) Other dermatologicals
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

🧪 What is this product?

This is a topical lotion conditioner containing pyrithione zinc, an antimicrobial ingredient commonly used in over-the-counter scalp and hair care products. Pyrithione zinc is typically included to help reduce flaking and irritation associated with certain scalp conditions. The product is marketed as an OTC monograph drug, meaning it follows FDA's established safety and effectiveness rules for this category rather than being individually approved. It is applied directly to the scalp and hair during regular hair care routines.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
84126-0906-31 You're viewing this Main listing 315 mL in 1 TUBE 2026-09-01 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
nioxin PRO CLINICAL SCALP RECOVERY moisturizing conditioner .5 g/100mL 82157-0012-10 Wella 1000 ml — — FDA listed —
Head and Shoulders Smooth and Silky Conditioner .5 g/100mL 84126-0234-31 The 315 ml — — FDA listed —
Head and Shoulders Deep Moisture Hair and Scalp Conditioner .5 g/100mL 69423-0197-31 The 315 ml — — Discontinued —
Head and Shoulders Supreme Detox and Hydrate Conditioner .5 g/100mL 69423-0347-27 The 278 ml — — FDA listed —
13.5oz 2 In 1 Dandruff Hair Cleanse and Conditioner - Eucalyptus and Mint .5 g/100mL 57337-0178-01 Rejoice 400 ml — — FDA listed —
Head and Shoulders Hair and Scalp Conditioner Green Apple .5 g/100mL 69423-0172-32 The 325 ml — — FDA listed —
Head and Shoulders Supreme Soothe and Strengthen Conditioner .5 g/100mL 69423-0349-27 The 278 ml — — FDA listed —
13.5oz 2 In 1 Dandruff Hair Cleanse and Conditioner - Shea and Cocoa Butter .5 g/100mL 57337-0179-01 Rejoice 400 ml — — FDA listed —
Head and Shoulders Conditioner Smooth and Silky .5 g/100mL 69423-0103-10 The 10 ml — — FDA listed —
Head and Shoulders Supreme Color Protect Conditioner .5 g/100mL 69423-0350-27 The 278 ml — — FDA listed —
Royal Oils by head and shoulders Moisture Renewal Scalp Balancing Conditioner .5 g/100mL 69423-0571-40 The 400 ml — — FDA listed —
Head and Shoulders Shea Butter Hair and Scalp Conditioner .5 g/100mL 69423-0669-32 The 325 ml — — FDA listed —
Pyrithione Zinc 0.5 Dandruff .5 g/100mL 52000-0416-12 Universal 355 ml — — Discontinued —
Head and Shoulders Supreme Nourish and Smooth Conditioner .5 g/100mL 69423-0348-27 The 278 ml — — FDA listed —
Mielle Lavender and Lychee Scalp Soothing Conditioner .5 g/100mL 84126-0258-35 The 355 ml — — FDA listed —
Head and Shoulders Dry Scalp Care Hair and Scalp Conditioner .5 g/100mL 69423-0160-32 The 325 ml — — FDA listed —
Pyrithione Zinc 0.5 2in1 Dandruff Conditioner .5 g/100mL 52000-0415-12 Universal 355 ml — — Discontinued —
Head and Shoulders White Charcoal Daily Hair and Scalp Conditioner .5 g/100mL 69423-0279-31 The 315 ml — — Discontinued —
Head and Shoulders Coconut Daily Hair and Scalp Conditioner .5 g/100mL 69423-0319-25 The 250 ml — — FDA listed —
Smooth And Soft Dandruff .5 g/100mL 52000-0452-12 Universal 355 ml — — FDA listed —
Everyday Clean Dandruff .5 g/100mL 76176-0131-01 NINGBO 355 ml — — FDA listed —
Smooth And Soft Dandruff .5 g/100mL 76176-0132-01 NINGBO 355 ml — — FDA listed —
TEA TREE Oil DANDRUFF .5 g/100mL 52000-0455-12 Universal 355 ml — — FDA listed —
Itchy Scalp Relief Dandruff .5 g/100mL 76176-0134-01 NINGBO 355 ml — — FDA listed —
Itchy Scalp Relief Dandruff .5 g/100mL 52000-0453-12 Universal 355 ml — — FDA listed —
Everyday Clean Dandruff .5 g/100mL 52000-0454-12 Universal 355 ml — — FDA listed —
TEA TREE Oil DANDRUFF .5 g/100mL 76176-0133-01 NINGBO 355 ml — — FDA listed —
Head and Shoulders Scalp Restore Nourishing Conditioner .5 g/100mLthis 84126-0906-31 The 315 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2026
On the market since
Sep 2026
📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII LKG8494WBH
    Benzyl alcohol is a clear liquid used as a preservative and solvent in medicines. It helps prevent bacterial and fungal growth and dissolves other ingredients to create uniform liquid formulations.
  • UNII 3XUS85K0RA
    Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
  • UNII 5THT33P7X7
    A waxy, lipid-like substance derived from animal or plant sources. It helps soften and moisturize the skin by acting as an emollient and skin-conditioning agent in topical medicines and creams.
  • UNII F1X8L2B00J
    A naturally derived fatty substance that helps bind and condition the product's texture. It works as an emollient and skin-conditioning agent in topical formulations, helping maintain moisture and smoothness.
  • UNII 4370DF050B
    Ceramide NP is a waxy, lipid-based substance that mimics natural skin oils. It's used in topical formulations as an emollient and skin-conditioning agent to help soften, smooth, and protect the skin barrier.
  • UNII 936JST6JCN
    Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
  • UNII 97C5T2UQ7J
    Cholesterol is a fatty substance found naturally in animal tissues. In medications, it's used as an ingredient in liposomal formulations and lipid-based drug delivery systems to help encapsulate and stabilize active drugs for better absorption.
  • UNII 2968PHW8QP
    A weak organic acid derived from citrus fruits or made through fermentation. It works as a buffer to control pH, a preservative to extend shelf life, and a flavoring agent in medications.
  • UNII 92RU3N3Y1O
    Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
  • UNII 3KX376GY7L
    Glutamic acid is an amino acid used in pharmaceuticals as a buffer and pH regulator. It helps maintain the medicine's chemical stability and proper acidity level.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII YQO029V1L4
    A mineral compound that acts as a filler and acid buffer in medicines. It helps give the tablet its size and shape while neutralizing stomach acid to protect the active ingredient.
  • UNII 25X51I8RD4
    Niacinamide is a form of vitamin B3, a water-soluble nutrient. In medicines, it may be added as a nutritional supplement or to support skin health, though its primary role here is as an active ingredient rather than a traditional inactive filler.
  • UNII 50C1307PZG
    Pentylene glycol is a humectant and preservative helper derived from petroleum or plant sources. It draws moisture into the product and helps prevent bacterial growth, keeping medicines stable during storage.
  • UNII HIE492ZZ3T
    Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
  • UNII GIN46U9Q2Q
    Phytosphingosine is a naturally derived fatty compound that helps stabilize and thicken skincare and cosmetic formulations. It works as an emollient and conditioning agent to improve texture and skin feel in topical products.
  • UNII A4V5C6R9FB
    Piroctone olamine is a antimicrobial compound used in medicines as a preservative or antifungal agent. It helps prevent bacterial and fungal growth in topical formulations like shampoos and skin products.
  • UNII 7T1F30V5YH
    A synthetic emulsifier derived from sorbitol and oleic acid. It helps mix oil and water-based ingredients together and keeps them from separating in liquid formulations.
  • UNII OJ245FE5EU
    Sodium benzoate is a salt derived from benzoic acid, a preservative. It's added to medicines to prevent growth of bacteria, fungi, and other microorganisms that could spoil the product.
  • UNII K7VEI00UFR
    A synthetic chemical derived from stearic acid, used primarily as an antistatic agent and conditioning ingredient in tablet formulations to reduce friction and improve powder flow during manufacturing.
  • UNII 2KR89I4H1Y
    Stearyl alcohol is a waxy, fatty substance derived from natural oils or made synthetically. It acts as an emulsifier and thickener in medicines, helping mix ingredients together and give the product the right texture.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII EQR32Y7H0M
    Zinc carbonate is an inorganic mineral compound. It's used in medicines as a buffer and absorbent to help maintain pH balance and control moisture in solid dosage forms.

23 inactive ingredients listed in the exact product block matched to this NDC.

The official label also stateswater, stearyl alcohol, cetyl alcohol, stearamidopropyl dimethylamine, glycerin, citric acid, glutamic acid, fragrance, dimethicone, phenoxyethanol, benzyl alcohol, sodium benzoate, butylene glycol, pentylene glycol, neosetophoma cerealis extract, polysorbate 20, zinc carbonate, piroctone olamine, niacinamide, ceramide np, ceramide ap, cholesterol, phytosphingosine, magnesium carbonate hydroxide, ceramide eop

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerThe Procter & Gamble Manufacturing Company
FDA applicationM032 (OTC MONOGRAPH DRUG)
Labeler code84126
First marketedSep 2026
Product typeHuman Otc Drug
Portfolio850 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 11 words ▾

Uses helps prevent recurrence of flaking and itching associated with dandruff.

⏱️ Dosage and Administration 31 words ▾

Directions for best results use at least twice a week or as directed by a doctor. apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well.

⚠️ Warnings 65 words ▾

Warnings For external use only. When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed. Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

🧪 Active Ingredient 5 words ▾

Active ingredient Pyrithione zinc 0.5%

🧪 Inactive Ingredients 46 words ▾

Inactive ingredients water, stearyl alcohol, cetyl alcohol, stearamidopropyl dimethylamine, glycerin, citric acid, glutamic acid, fragrance, dimethicone, phenoxyethanol, benzyl alcohol, sodium benzoate, butylene glycol, pentylene glycol, neosetophoma cerealis extract, polysorbate 20, zinc carbonate, piroctone olamine, niacinamide, ceramide np, ceramide ap, cholesterol, phytosphingosine, magnesium carbonate hydroxide, ceramide eop

🎯 Purpose 2 words ▾

Purpose Anti-dandruff

📄 When Using This Product 16 words ▾

When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

📄 Stop Use and Ask a Doctor If 21 words ▾

Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed.

📄 Keep Out of Reach of Children 23 words ▾

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Questions or Comments 4 words ▾

Questions (or comments)? 1-800-723-9569

📄 Package Label / Principal Display Panel 33 words ▾

PRINCIPAL DISPLAY PANEL - 315 mL Tube Label head & shoulders pyrithione zinc dandruff conditioner SCALP RESTORE NOURISHING CONDITIONER FOR DRY SCALPS 2 % HydraSC plus COMPLEX

10.6 FL OZ (315 mL) HS

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by The Procter & Gamble Manufacturing Company. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
The Procter & Gamble Manufacturing Company is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 84126-0905-30 · The 84126-0907-22 · The →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.