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APUREE PRO Nailtific Maximum Strength Antifungal Patches 1 g Patch — NDC 84167-0335-01 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

APUREE PRO Nailtific Maximum Strength Antifungal Patches 1 g Patch — NDC 84167-335-01 (Billing 84167-0335-01)

by Guangzhou Meixi Biotechnology Co., Ltd. · 2 PATCH in 1 BOX / 32 PATCH in 1 PATCH

This is a package of APUREE PRO Nailtific Maximum Strength Antifungal Patches 1 g Patch from Guangzhou Meixi Biotechnology Co., Ltd., marketed since May 2026 and currently FDA-listed. It is this product's only package size.

NDC 84167-0335-01
🏷️ FDA NDC (as labeled) 84167-335-01 billing pads the product segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 84167-335-01
Product NDC 84167-335
11-digit billing NDC 84167033501
RxCUI 2677690
UNII 06KB629TKV
Application # M005
SPL Set ID 5218bd5d-53b4-107f-e063-6394a90ae769
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2026-05-18
Route TOPICAL
Dosage form PATCH
Substance TOLNAFTATE
Quick answers
  • RxCUI (RxNorm): 2677690
Why two NDCs? The FDA registers this code as 84167-335-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 84167-0335-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Other antifungals for topical use class.

Drug family (ATC) Other antifungals for topical use
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It treats fungal skin infections like athlete's foot, ringworm and, in some products, jock itch. Many products also help prevent athlete's foot. Some are made for skin around the n...
  • Wash and dry the area well, then apply a thin layer. Most products are used twice a day, morning and night. The length of use varies, often 4 weeks for athlete's foot and ringworm,...
  • The main one is skin irritation. If that happens, stop using it and talk to a doctor.
  • Call if you see no improvement within 4 weeks for athlete's foot or ringworm, or 2 weeks for jock itch. Call if irritation develops. Call right away if anyone swallows it.
📖 Read our full Tolnaftate guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
84167-0335-01 You're viewing this Main listing 2 PATCH in 1 BOX / 32 PATCH in 1 PATCH 2026-05-18 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
FungiFree Fungal Nail Patches 1 g/100g 83364-0013-01 YITONGBADA 4084101 patches — — FDA listed —
APUREE Pure Nailtific Extra-Strength Fungal Nail Patches 1 g 84167-0332-23 Guangzhou 5 patches — — FDA listed —
APUREE PRO Nailtific Maximum Strength Antifungal Patches 1 gthis 84167-0335-01 Guangzhou 2 patches — — FDA listed —
APUREE Nailtific Maximum Strength Antifungal Patches PRO 1 g 84167-0416-01 Guangzhou 2 patches — — FDA listed —
Puvida Fungal Nail 1 g/1001 85248-0153-01 Jiangxi 32 patches — — FDA listed —
NATURAL CURES FUNGAL NAIL Patches 1 g/1001 85248-0202-01 Jiangxi 52 patches — — FDA listed —
HuiPoLii NAIL PFLASTER 1 g/1001 85248-0206-01 Jiangxi 32 patches — — FDA listed —
TINGOLE FUNGAL NAIL Patches 1 g/1001 85248-0221-01 Jiangxi 21 patches — — FDA listed —
Fungal Nail Nighttime Renewal Patches 1 g/1001 85569-0009-01 100 33554432 patches — — FDA listed —
Initial Treatonic FUNGAL NAIL RENEWAL PATCHES 1 mg/1001 85569-0013-01 100 33554432 patches — — FDA listed —
Fungal Nail Patches .01 g 85966-0006-01 GUANGZHOU 32 patches — — FDA listed —
Saviland PRO Extra Strength Toenail Renewal Patches .01 g 85966-0014-01 GUANGZHOU 35 patches — — FDA listed —
Saviland SSPro X Series Extra Strength Toenail Renewal Patches .01 g 85966-0015-01 GUANGZHOU 18 patches — — FDA listed —
SSPROTIP X Extra Strength Nail Renewal Patches .01 g 85966-0016-01 GUANGZHOU 38 patches — — FDA listed —
Vrenmol Extra Strength Nail Renewal Patches .01 g 85966-0018-01 GUANGZHOU 34 patches — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2026
On the market since
May 2026
📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 36HQN158VC
    Alpha-bisabolol is a naturally derived oily liquid from plant sources. It works as a fragrance, flavor, and skin-conditioning agent in topical medicines and cosmetic products.
  • UNII 9E8X80D2L0
    A synthetic form of vitamin E used as an antioxidant and preservative in medications. It helps prevent the active ingredients from degrading when exposed to oxygen or light.
  • UNII L65MV77ZG6
    A naturally occurring alcohol compound derived from plants, used as a fragrance and flavoring agent in medicines to improve taste and smell.
  • UNII 344S277G0Z
    Allantoin is a naturally derived compound that helps soften and soothe skin. In medicines, it works as a skin-conditioning agent and may help support wound healing and reduce irritation in topical formulations.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII 1O6C93RI7Z
    Dexpanthenol is a naturally derived compound related to B vitamins. It acts as a humectant and skin conditioning agent, helping the medicine absorb moisture and maintain softness in topical formulations.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 712K4CDC10
    A weak acid naturally produced by white blood cells. In medicines, it acts as a preservative and antimicrobial agent to prevent bacterial and fungal growth in liquid formulations.
  • UNII 3B8D35Y7S4
    A weak organic acid made from natural or synthetic sources. It works as a pH buffer and preservative to maintain the medicine's stability and prevent bacterial growth during storage.
  • UNII 1AEY1M553N
    A natural oil extracted from spearmint or field mint leaves, used as a flavoring agent to give medicines a minty taste and aroma. It may also provide a cooling sensation in topical products.
  • UNII AV092KU4JH
    A natural oil extracted from peppermint plants. It's used as a flavoring agent to mask bitter tastes and add a refreshing mint flavor to medicines, making them easier to take.
  • UNII 5D6TC4BRWV
    Polyacrylamide is a synthetic polymer used as a thickener and stabilizer in medicines. It helps maintain consistent texture and prevents separation of ingredients in liquid or semi-solid formulations.
  • UNII 8W8T17847W
    A nitrogen-containing chemical compound used in pharmaceuticals as a humectant to retain moisture, and sometimes as a keratolytic agent in topical formulations to help soften and remove dead skin cells.

13 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesAqua,Urea,Lactic Acid,Terpinen-4-ol,Glycerin,Polyacrylamide,Seaweed Extract,Panthenol, Tocopheryl Acetate,Bisabolol,Allantoin,Mentha Arvensis Leaf Oil,Menthol & Essential Oil Complex

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerGuangzhou Meixi Biotechnology Co., Ltd.
FDA applicationM005 (OTC MONOGRAPH DRUG)
Labeler code84167
First marketedMay 2026
Product typeHuman Otc Drug
Portfolio17 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 1 words ▾

Antifungal

⏱️ Dosage and Administration 1 words ▾

Antifungal

🧪 Active Ingredient 1 words ▾

Tolnaftate

🧪 Inactive Ingredients 12 words ▾

Aqua,Urea,Lactic Acid,Terpinen-4-ol,Glycerin,Polyacrylamide,Seaweed Extract,Panthenol, Tocopheryl Acetate,Bisabolol,Allantoin,Mentha Arvensis Leaf Oil,Menthol & Essential Oil Complex

🎯 Purpose 1 words ▾

Antifungal

📄 Keep Out of Reach of Children 6 words ▾

keep out of reach of children

📄 Package Label / Principal Display Panel 1 words ▾

11

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Guangzhou Meixi Biotechnology Co., Ltd.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Guangzhou Meixi Biotechnology Co., Ltd. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 84167-0332-23 · Guangzhou 84167-0364-02 · Guangzhou →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.