Acne Relief Cream NIACINAMIDE,SALICYLIC ACID,CENTELLA ASIATICA ROOT,COPTIS CHINENSIS ROOT 400 mg/20g; 4 mg/20g; 48 mg/20g; 152 mg/20g Cream, 20 g
🆔 Identity & classification
Where does this data come from?
🏭 Manufacturer & labeler
Where does this data come from?
🩺 Clinical
This is a topical cream marketed as an over-the-counter monograph product for acne relief. It contains salicylic acid, a keratolytic agent typically used to help exfoliate and unclog pores, and niacinamide, which is commonly used to support skin barrier function and reduce irritation. The formula also includes centella asiatica root and coptis chinensis root, botanical ingredients that appear in skincare products for their soothing properties. This product is applied directly to the skin.
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Supplement & herbal interactions
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🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII TR046Y3K1G
A liquid alcohol derived from petroleum or plant sources. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
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Acacia is a natural gum derived from acacia tree sap. It serves as a binder, thickener, and emulsifier to help hold ingredients together, improve texture, and stabilize the medicine.
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UNII 344S277G0Z
Allantoin is a naturally derived compound that helps soften and soothe skin. In medicines, it works as a skin-conditioning agent and may help support wound healing and reduce irritation in topical formulations.
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Arginine is an amino acid used in medicines as a buffer and pH adjuster. It helps maintain the proper acidity level and stability of liquid formulations.
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Aspalathus linearis leaf is a plant extract from rooibos tea. It's used in medicines as a natural flavor and color agent, and may help preserve the product's stability.
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Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
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UNII E4F12ROE70
A refined mineral oil derived from crude petroleum containing 13 to 14 carbon chains. It acts as a solvent, emollient, and carrier in topical formulations to help dissolve active ingredients and improve product texture and spreadability.
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UNII C9H2L21V7U
A fat derived from coconut or palm oil containing shorter fatty acid chains. It serves as a solvent and carrier to help dissolve or suspend active ingredients, improving absorption and stability in liquid formulations.
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A spicy pepper extract used as a flavoring agent in medicines. It adds taste to mask bitter drug flavors and improve palatability, especially in liquid or chewable formulations.
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UNII 0A5MM307FC
A synthetic polymer that absorbs water and forms a thick, gel-like substance. In medicines, it works as a thickener and stabilizer to improve texture and help ingredients stay mixed together in creams, gels, and lotions.
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UNII 4370DF050B
Ceramide NP is a waxy, lipid-based substance that mimics natural skin oils. It's used in topical formulations as an emollient and skin-conditioning agent to help soften, smooth, and protect the skin barrier.
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UNII 2DMT128M1S
A waxy solid derived from plant or animal sources. It acts as an emulsifier to blend oil and water components, and also thickens the medicine to give it the right texture and consistency.
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Cetearyl glucoside is a plant-derived surfactant made from vegetable oils and glucose. It helps oils and water mix together in creams and lotions, and can also soften and smooth the skin feel of the product.
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Chitosan oligosaccharide is a naturally derived carbohydrate made from shellfish shells or fungal sources. It acts as a binder to hold tablet ingredients together and may help the body absorb other compounds in the medicine.
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Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
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A sulfur-containing organic compound used as a solvent and penetration enhancer in medicines. It helps dissolve active ingredients and improve their absorption through skin or mucous membranes.
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Edetate disodium is a chemical compound that binds and removes certain metal ions. In medicines, it acts as a preservative and stabilizer by preventing metals like calcium from interfering with the product's shelf life and consistency.
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Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
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Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
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A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
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A synthetic compound used in medicines as a preservative and antimicrobial agent. It helps prevent bacterial and fungal growth, extending the product's shelf life.
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A plant-derived thickening agent made from cellulose. It increases viscosity and helps form a gel or paste consistency in medications, and may serve as a binder or coating material in various formulations.
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Inositol is a naturally occurring sugar-like compound. It acts as an osmotic agent and sweetener in medications, helping draw water into the formulation and improve taste.
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A synthetic surfactant derived from lauryl alcohol and ethylene oxide. It helps dissolve and mix oily and watery ingredients in liquid formulations, and may improve how the medicine spreads or is absorbed.
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A plant extract from Japanese honeysuckle flowers used as a natural flavoring and fragrance ingredient in medicines. It may also help preserve the product and add pleasant taste or aroma.
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A starch-derived carbohydrate produced by breaking down corn, potato, or tapioca starch. It functions as a filler and binder to give the medicine bulk and texture, and sometimes as a mild sweetener or texture enhancer in powders and tablets.
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Tea tree oil is an essential oil extracted from the leaves of the Australian tea tree plant. In medicines, it typically serves as a flavoring agent, fragrance, or antimicrobial component in topical formulations.
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UNII L7T10EIP3A
A cooling compound from mint plants used as a flavoring agent and to create a fresh sensation in medicines. It helps mask bitter tastes and improve how the product feels in the mouth.
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UNII YD01N1999R
A waxy substance made from polyethylene glycol and stearic acid. It helps mix oil and water-based ingredients together and serves as an emulsifier and solubilizer in liquid and semi-solid medicines.
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UNII PBG27B754G
Phellodendron amurense bark is a plant-derived ingredient from the cork tree. It functions as a natural preservative and antimicrobial agent to help maintain product stability and prevent microbial growth.
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Phenoxyethanol is a synthetic preservative and antimicrobial agent used to prevent bacterial and fungal growth in medicines and cosmetic products, extending shelf life and maintaining product safety.
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A plant extract from the kava root, used as a flavoring agent to add taste to medicines. It may also help mask bitter flavors in oral formulations.
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A synthetic polymer formed by linking acrylamide molecules together. It functions as a binder and thickener in medicines, helping hold ingredients together and adjust the product's texture and consistency.
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UNII 5X73DDS97A
A synthetic polymer used as a conditioning and antistatic agent. In medicines, it helps improve texture, reduce static buildup, and enhance how the product feels or flows.
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Salvia miltiorrhiza root is a plant extract used in traditional medicine formulations. It may serve as a flavoring agent, natural colorant, or functional ingredient to support the product's intended therapeutic profile.
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A plant extract from the roots of Chinese skullcap, used as a natural coloring agent and to add mild flavor to medicines. It may also help preserve the product's stability.
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Jojoba oil is a natural liquid wax extracted from jojoba plant seeds. It's used in medicines as an emollient and lubricant to soften and smooth the product, and sometimes as a carrier or penetration enhancer.
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Hyaluronate sodium is a natural carbohydrate that holds moisture. It's used in medicines as a lubricant, thickener, and moisture-retaining agent to improve texture and delivery of the active ingredient.
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A plant extract from sophora flavescens root used as a natural colorant and flavoring agent in medicines. It may also help preserve the product and provide texture.
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Sophora flavescens is a plant extract used in medicines as a natural thickening agent and skin-conditioning ingredient. It helps adjust the medicine's texture and may support formulation stability.
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Sorbitan olivate is an emulsifier derived from sorbitol and olive oil. It helps blend water and oil ingredients together to maintain consistent texture and appearance throughout the medicine.
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UNII R0ZB2556P8
Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
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Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
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Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.
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UNII 3CIP16A418
A plant extract from Sichuan pepper fruit used as a flavoring agent and natural fragrance component in medicines. It adds taste and aroma to make medications more palatable.
45 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
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💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Acne Relief Cream 400 mg/20g; 4 mg/20g; 48 mg/20g; 152 mg/20gthis 84509-0110-01 | Guangzhou | 20 g | — | — | FDA listed | — |
Where does this data come from?
⏳ Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 84509-0110-01 You're viewing this | 20 g in 1 BOTTLE (84509-110-01) | 2026-05-30 | Active |
🧭 About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | — Not published for this NDC No photo available yet for this listing. |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
Questions about this listing
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Where does this data come from?
📄 FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses STEP 1: Clean the skin and keep it dry. STEP 2: Take an appropriate amount of this product and apply to the skin. STEP 3: Gently massage with your fingertips to promote absorption.
⏱️ Dosage and Administration ▾
DOSAGE Approximately 0.01-0.02 oz each time.
⚠️ Warnings ▾
Warnings 1.For external use only.2.Avoid contact with eyes.3.Keep out of reach of children.4.Discontinue use immediately if you experience any allergic reactions and consult a physician.
🧪 Active Ingredient ▾
Active Ingredients SALICYLIC ACID ...... 0.76% ...... Anti-Acne NIACINAMIDE ...... 2% ...... Fades Acne Scars COPTIS CHINENSIS ROOT EXTRACT ...... 0.24% ......Soothe Acne CENTELLA ASIATICA EXTRACT ...... 0.02% ......Soothe Acne
🧪 Inactive Ingredients ▾
Inactive Ingredients WATER, BUTYLENE GLYCOL, GLYCERIN, PHELLODENDRON AMURENSE BARK EXTRACT, SALVIA MILTIORRHIZA EXTRACT, LONICERA JAPONICA EXTRACT, ASPALATHUS LINEARIS EXTRACT, SOPHORA FLAVESCENS EXTRACT, SCUTELLARIA BAICALENSIS ROOT EXTRACT, 1,2-HEXANEDIOL, HYDROXYACETOPHENONE, ZANTHOXYLUM BUNGEANUM FRUIT EXTRACT, SOPHORA ANGUSTIFOLIA ROOT EXTRACT, CAPSICUM FRUTESCENS FRUIT EXTRACT, PIPER METHYSTICUM ROOT EXTRACT, QUATERNIUM-73, CETEARYL GLUCOSIDE, SORBITAN OLIVATE, CETEARYL ALCOHOL, ACACIA SENEGAL GUM, MALTODEXTRIN, CHITOSAN, CAPRYLIC/CAPRIC TRIGLYCERIDE, DIMETHICONE, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, GLYCERYL STEARATE, PEG-100 STEARATE, INOSITOL, DIMETHYL SULFONE, PHENOXYETHANOL, ETHYLHEXYLGLYCERIN, POLYACRYLAMIDE, C13-14 ISOPARAFFIN, LAURETH-7, CARBOMER, ARGININE, ALLANTOIN, MENTHOL, XANTHAN GUM, HYDROXYETHYLCELLULOSE, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, DISODIUM EDTA, SODIUM HYALURONATE, CERAMIDE NP, TOCOPHEROL
🎯 Purpose ▾
Purpose Acne treatment
📋 Description ▾
Product Name Acne Relief Cream
Manufacturer Guangzhou Senmai Biotechnology Co.,Ltd.
Address Floor 1-4,Building A,Guanger Smart Industrial Park,No.2 Qianyi East Road, Shiling Town,Huadu District,Guangzhou,Guangdong,CN(China)
Capacity 20ml/0.7fl.oz
Shelf Life Shelf Life ·3 Years
Place of Origin Made in PRC