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Arthcal Estriol Face Cream for Women SHEA BUTTER,TOCOPHEROL,Estriol 1 g/100g; 2 g/100g; .2 g/100g Cream, 50 g — NDC 85212-0016-01 package photo

Arthcal Estriol Face Cream for Women SHEA BUTTER,TOCOPHEROL,Estriol 1 g/100g; 2 g/100g; .2 g/100g Cream, 50 g

by Beijing JUNGE Technology Co., Ltd. · 50 g in 1 CAN (85212-0016-1)
NDC 85212-0016-01
🏷️ FDA NDC (as labeled) 85212-0016-1 billing pads the package segment with a zero
OTC On market Non-controlled
🗂️ Data synced Aug 27, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 85212-0016-1
Product NDC 85212-0016
11-digit billing NDC 85212001601
UNII R0ZB2556P8, K49155WL9Y, FB33469R8E
Application # 505G(a)(3)
SPL Set ID 2f2f71c2-763d-0290-e063-6394a90a72ca
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2025-01-10
Route EXTRACORPOREAL
Dosage form CREAM
Substance TOCOPHEROL; BUTYROSPERMUM PARKII (SHEA) BUTTER; ESTRIOL
Why two NDCs? The FDA registers this code as 85212-0016-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 85212-0016-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerBeijing JUNGE Technology Co., Ltd.
FDA application505G(a)(3) (OTC MONOGRAPH DRUG)
Labeler code85212
First marketedJan 2025
Product typeHuman Otc Drug
Portfolio34 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

🧪 What is this product?

This is an over-the-counter facial cream marketed under FDA's monograph rules for topical skin-care products. It contains estriol (a form of estrogen), shea butter (a skin conditioning agent), and tocopherol (vitamin E, commonly used as an antioxidant and moisturizer). Products with these ingredients are typically intended to address skin texture and appearance on the face. This product is applied to the skin surface only.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

ShapeFreeform
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • 0.015 g / 100 g UNII TR046Y3K1G
    A liquid alcohol derived from petroleum or plant sources. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
  • 0.5 g / 100 g UNII RUE8E6T4NB
    Aloe vera leaf juice is a clear gel extracted from aloe vera plant leaves. It's used in medicines as a lubricant, emollient, and preservative to soothe skin contact and help keep the product stable.
  • 74.21 g / 100 g UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • 0.015 g / 100 g UNII 94ZLA3W45F
    Arginine is an amino acid used in medicines as a buffer and pH adjuster. It helps maintain the proper acidity level and stability of liquid formulations.
  • 5 g / 100 g UNII 3XUS85K0RA
    Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
  • 0.1 g / 100 g UNII VC855RRT77
    A natural oil extracted from green tea leaves. It is used in medications as a fragrance and flavoring agent to improve taste and aroma.
  • 0.015 g / 100 g UNII 00YIU5438U
    Caprylyl glycol is a clear liquid derived from coconut oil. In medicines, it acts as a humectant to retain moisture, a preservative booster to prevent microbial growth, and a solvent to help dissolve or mix other ingredients.
  • 0.015 g / 100 g UNII 0A5MM307FC
    A synthetic polymer that absorbs water and forms a thick, gel-like substance. In medicines, it works as a thickener and stabilizer to improve texture and help ingredients stay mixed together in creams, gels, and lotions.
  • 1 g / 100 g UNII 2DMT128M1S
    A waxy solid derived from plant or animal sources. It acts as an emulsifier to blend oil and water components, and also thickens the medicine to give it the right texture and consistency.
  • 0.1 g / 100 g UNII K73E24S6X9
    A plant extract derived from black cohosh root, used primarily as a natural flavoring or botanical ingredient in formulations. It may also function as a preservative or processing agent.
  • 0.015 g / 100 g UNII AKN3KSD11B
    Orange oil obtained by cold pressing orange peel. It serves as a flavoring agent and fragrance in medicines to improve taste and aroma.
  • 5 g / 100 g UNII Q9L0O73W7L
    Coconut oil is a natural fat extracted from coconut fruit. It's used in medicines as a lubricant, emollient, or carrier to help dissolve or deliver active ingredients smoothly through the formulation.
  • 5 g / 100 g UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • 0.015 g / 100 g UNII S270N0TRQY
    Hyaluronic acid is a naturally occurring substance found in skin and joints. In medicines, it acts as a moisturizer and thickening agent to improve texture and help the product spread smoothly.
  • 0.1 g / 100 g UNII CUQ3A77YXI
    Panax ginseng root is a plant extract traditionally used in herbal preparations. In medications, it may serve as an active botanical ingredient or be included for flavoring and as a natural preservative or binder in formulations.
  • 0.5 g / 100 g UNII 7TRV45YZF7
    A plant extract from Japanese knotweed root used as a natural ingredient. It functions as an antioxidant and preservative to help maintain product stability and shelf life.
  • 0.5 g / 100 g UNII 892O4599HF
    A plant extract from the pueraria mirifica root used in dietary supplements and some formulations as a natural ingredient and potential texture or consistency modifier in tablets and capsules.
  • 0.1 g / 100 g UNII O2ZTS50U5E
    A plant extract from pomegranate fruit used as a natural coloring agent and flavor component in medications. It may also provide antioxidant properties to help preserve the medicine's stability.
  • 2 g / 100 g UNII 724GKU717M
    Jojoba oil is a natural liquid wax extracted from jojoba plant seeds. It's used in medicines as an emollient and lubricant to soften and smooth the product, and sometimes as a carrier or penetration enhancer.
  • 0.5 g / 100 g UNII 71B37NR06D
    Soy isoflavones are natural plant compounds extracted from soybeans. They are used in dietary supplements and some medications as an active botanical ingredient to support formulation claims, though they function as an additive rather than a traditional inactive excipient.
  • 2 g / 100 g UNII GW89575KF9
    Squalane is a lightweight oil derived from plant sources or synthesized. It acts as an emollient and lubricant in formulations, helping ingredients blend smoothly and improving product texture and spreadability.
  • 0.1 g / 100 g UNII 4JS0838828
    A plant extract from red clover flowers used in herbal or natural formulations. It may serve as an active botanical ingredient or flavor/color component, though its specific role depends on the product's intended use.

22 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesAQUA BUTYLENE GLYCOL GLYCERIN COCOS NUCIFERA (COCONUT) OIL SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL SQUALANE CETEARYL ALCOHOL ALOE BARBADENSIS LEAF JUICE SOY ISOFLAVONES POLYGONUM CUSPIDATUM ROOT EXTRACT PUERARIA MIRIFICA ROOT EXTRACT CIMICIFUGA RACEMOSA ROOT EXTRACT PUNICA GRANATUM FRUIT EXTRACT TRIFOLIUM PRATENSE (CLOVER) FLOWER EXTRACT CAMELLIA SINENSIS LEAF EXTRACT PANAX GINSENG ROOT EXTRACT CITRUS AURANTIUM DULCIS (ORANGE) PEEL OIL HYALURONIC ACID CARBOMER ARGININE 1,2-HEXANEDIOL CAPRYLYL GLYCOL

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Arthcal Estriol Face Cream for Women 1 g/100g; 2 g/100g; .2 g/100gthis 85212-0016-01 Beijing 50 g — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2025
On the market since
Jan 2025
📍
2026
Currently FDA-listed
1 year listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
85212-0016-01 You're viewing this 50 g in 1 CAN (85212-0016-1) 2025-01-10 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 85212-0016-1, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 85212-0016-01, written without dashes as 85212001601. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 85212-0016-01, the first segment (85212) is the labeler code FDA assigned to Beijing JUNGE Technology Co., Ltd.; the middle segment (0016) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Beijing JUNGE Technology Co., Ltd.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Beijing JUNGE Technology Co., Ltd. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 31 words ▾

Apply to clean skin (face, neck, or body) twice daily. For optimal results, combine with a daily skincare routine. Consult your healthcare provider before use if you have specific medical concerns.

⏱️ Dosage and Administration 1 words ▾

50G/1.76OZ

⚠️ Warnings 13 words ▾

For external use only. Keep out of reach of children.Avoid contact with eyes.

🧪 Active Ingredient 6 words ▾

BUTYROSPERMUM PARKII (SHEA BUTTER) TOCOPHEROL Estriol

🧪 Inactive Ingredients 64 words ▾

AQUA BUTYLENE GLYCOL GLYCERIN COCOS NUCIFERA (COCONUT) OIL SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL SQUALANE CETEARYL ALCOHOL ALOE BARBADENSIS LEAF JUICE SOY ISOFLAVONES POLYGONUM CUSPIDATUM ROOT EXTRACT PUERARIA MIRIFICA ROOT EXTRACT CIMICIFUGA RACEMOSA ROOT EXTRACT PUNICA GRANATUM FRUIT EXTRACT TRIFOLIUM PRATENSE (CLOVER) FLOWER EXTRACT CAMELLIA SINENSIS LEAF EXTRACT PANAX GINSENG ROOT EXTRACT CITRUS AURANTIUM DULCIS (ORANGE) PEEL OIL HYALURONIC ACID CARBOMER ARGININE 1,2-HEXANEDIOL CAPRYLYL GLYCOL

🎯 Purpose 10 words ▾

Reduce Hot Flashes Menopause Relief Menstrual Cycle Support Hormone Balance

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 85212-0015-01 · Beijing 85212-0018-01 · Beijing →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.