HomeNDC LookupIngredientsSalicylic Acid Spot › 87415-0100-04
The Acne Spot Treatment Salicylic Acid 2 g/100g Gel, 1 tube — NDC 87415-0100-04 package photo

The Acne Spot Treatment Salicylic Acid 2 g/100g Gel, 1 tube

by Spotless, Inc. · 1 TUBE in 1 CARTON (87415-100-04) / 12.48 g in 1 TUBE
NDC 87415-0100-04
🏷️ FDA NDC (as labeled) 87415-100-04 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Sep 10, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

🆔 Identity & classification

FDA NDC (as labeled) 87415-100-04
Product NDC 87415-100
11-digit billing NDC 87415010004
RxCUI 346298
UNII O414PZ4LPZ
Application # M006
SPL Set ID 4a1a3716-9eaf-6be4-e063-6294a90a31c3
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2026-05-21
Route TOPICAL
Dosage form GEL
Substance SALICYLIC ACID
Why two NDCs? The FDA registers this code as 87415-100-04 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 87415-0100-04. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Salicylic acid and derivatives class.

Drug family (ATC) Salicylic acid and derivatives, Other antifungals for topical use, Antiinflammatory agents, non-steroids
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerSpotless, Inc.
FDA applicationM006 (OTC MONOGRAPH DRUG)
Labeler code87415
First marketedMay 2026
Product typeHuman Otc Drug
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📖 What it is MedlinePlus · NLM

Topical salicylic acid is used to help clear and prevent pimples and skin blemishes in people who have acne. Topical salicylic acid is also used to treat skin conditions that involve scaling or overgrowth of skin cells such as psoriasis (a skin disease in which red, scaly patches form on some areas of the body), ichthyoses (inborn conditions that cause skin dryness and scaling), dandruff, corns, calluses, and warts on the hands or feet. Topical salicylic acid should not be used to treat genital warts, warts on the face, warts with hair growing from them, warts in the nose or mouth, moles, or b...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • It's designed to treat acne. Salicylic acid helps by loosening and removing dead skin cells that clog pores — the buildup that leads to breakouts. The multi-step system on this lab...
  • What is this salicylic acid product actually supposed to do for my skin?
  • Some mild tingling, stinging, and peeling is actually expected — that's the salicylic acid doing its job by clearing away dead skin cells. But if the burning or peeling feels exces...
  • My skin feels like it's burning and peeling. Is that normal?
📖 Read our full Salicylic Acid Topical guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 00YIU5438U
    Caprylyl glycol is a clear liquid derived from coconut oil. In medicines, it acts as a humectant to retain moisture, a preservative booster to prevent microbial growth, and a solvent to help dissolve or mix other ingredients.
  • UNII BQM438CTEL
    A plant-derived compound from green tea that acts as an antioxidant. It's used in formulations to help prevent degradation of active ingredients and maintain product stability over time.
  • UNII AR8RR3M6N9
    A plant-derived compound made from green tea extract. It's used as an antioxidant in medications to help protect other ingredients from breaking down during storage.
  • UNII 147D247K3P
    Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
  • UNII RH73PR9HMA
    A blend of beneficial microorganisms and enzymes used as a natural processing aid and probiotic ingredient. It may help with fermentation, digestive support, or improve the bioavailability of nutrients in the formulation.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII CQ2F5O6YIY
    A natural compound extracted from Centella asiatica plant used as an active skin-conditioning ingredient. It functions as a humectant and skin protectant to improve moisture retention and support skin barrier function in topical formulations.
  • UNII 25X51I8RD4
    Niacinamide is a form of vitamin B3, a water-soluble nutrient. In medicines, it may be added as a nutritional supplement or to support skin health, though its primary role here is as an active ingredient rather than a traditional inactive filler.
  • UNII WV9CM0O67Z
    Panthenol is a humectant and skin-conditioning agent derived from pantothenic acid. It's added to medicines to help retain moisture and soothe skin irritation.
  • UNII 50C1307PZG
    Pentylene glycol is a humectant and preservative helper derived from petroleum or plant sources. It draws moisture into the product and helps prevent bacterial growth, keeping medicines stable during storage.
  • UNII Q7UI015FF9
    A synthetic polymer material used as a thickener and stabilizer in liquid formulations. It helps create the right texture and prevents separation of ingredients in medicines and topical products.
  • UNII 05I15JNI2J
    A synthetic polymer that absorbs and holds moisture. Used in tablets and capsules as a super-disintegrant to help the medicine break apart quickly when swallowed, allowing faster drug release.
  • UNII NG5NG5733T
    A synthetic polymer derived from acrylic acid and taurine. It functions as a suspending agent and emulsifier, helping keep ingredients evenly distributed and preventing separation in liquid or semi-solid medicines.
  • UNII R0ZB2556P8
    Tocopherol is a form of vitamin E derived from plant oils. It acts as an antioxidant in medicines to prevent oils and fats from breaking down and spoiling during storage.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
  • UNII C32PQ86DH4
    Zinc PCA is a zinc salt of pyroglutamic acid, a naturally occurring amino acid derivative. It's used in medications as a skin-conditioning agent and to help maintain product stability and texture in topical formulations.

16 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesWater, Niacinamide, Glycerin, Pentylene Glycol, Sodium Polyacrylate, Polyacrylate Crosspolymer-6, Epigallocatechin Gallatyl Glucoside, Epigallocatechin Gallate, Madecassoside, Zinc PCA, Sphingomonas Ferment Extract, Panthenol, Sodium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Ethylhexylglycerin, Tocopherol

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMedingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Walgreens Acne Control Gel 20 mg/mL 00363-0269-83 WALGREEN 1 tube FDA listed
Artistry Studio Done With Zit Acne Treatment Clearing Gel 20 mg/mL 10056-0045-00 Access 1 tube FDA listed
Hero Cosmetics Pimple Correct Salicylic Acid Acne Treatment 20 mg/mL 10237-0003-00 Church 1 tube FDA listed
Acne Treatment Gel 20 mg/mL 31720-0301-08 S+ 1 bottle FDA listed
Eradikate Acne Mark Fading 2 g/100mL 43479-0112-51 KATE 1 bottle FDA listed
Clarifying Peel 2 g/100mL 46007-0102-11 Skin 20 ml Discontinued
ACNE SolutionS CLINICAL ADVANCED CLEARING gel 20 mg/mL 49527-0221-01 CLINIQUE 1 bottle Discontinued
Thayers Since 1847 Natural Remedies Blemish Clearing Witch Hazel Aloe Vera Formula Cleanser 20 mg/mL 49967-0051-01 L'Oreal 118 ml FDA listed
CeraVe Developed with Dermatologists Acne Control Acne Treatment 20 mg/mL 49967-0172-01 L'Oreal 1 tube FDA listed
Thayers Since 1847 Natural Remedies Blemish Clearing Witch Hazel Aloe Vera Formula Balm 20 mg/mL 49967-0530-01 L'Oreal 118 ml FDA listed
Vichy Laboratoires Normaderm Phytoaction Acne Control Daily Moisturizer 20 mg/mL 49967-0606-01 L'Oreal 1 bottle FDA listed
Vichy Laboratoires Normaderm Acne Control Daily Moisturizer 20 mg/mL 49967-0660-01 L'Oreal 1 bottle FDA listed
clear days ahead fast-acting salicylic acid acne spot treatment .3 g/15mL 50184-1020-01 Philosophy 15 ml FDA listed
Dr. Dennis Gross Alpha Beta On the Spot Eliminator 20 mg/mL 51326-0057-01 Topiderm, 1 tube FDA listed
GOODBYE ACNE Complete treatment gel .9638 g/48.19g 54031-0069-01 Peter 48.19 g FDA listed
BRODA Acne .4 g/20g 54111-0112-50 Bentley 20 g FDA listed
XtraCare Deep Cleaning Astringent 5 mg/237mg 57337-0035-01 Rejoice 237 mg FDA listed
Acne Defense Spot Treatment Merle Norman 2 g/100g 57627-0201-02 Merle 1 tube FDA listed
Image Clear Cell Acne Spot Treatment 20 g/1000g 60232-5022-01 Swiss-American 14 g FDA listed
Dry It Out Acne Spot Treatment 2 g/100mL 61197-0122-00 Pacifica 29 ml FDA listed
Gm Collin Puracne 20 mg/mL 64127-0195-01 Laboratoires 1 tube FDA listed
Overnight Clearing 20 mg/mL 68479-0706-00 Dermalogica, 2 ml FDA listed
Milani Erase Base Blemish Control Primer 20 mg/mL 68577-0103-00 Cosmax 1 tube FDA listed
PCA SKIN Intensive Clarity Treatment 2 g/100g 68726-0359-02 CP 1 tube FDA listed
PCA Gel 2 g/100mL 68726-0445-02 CP 1 bottle FDA listed
Spot Stopper Acne Spot Treatment 2 g/100mL 69366-0412-32 The 1 tube FDA listed
First Aid Beauty FAB Acne Spot Treatment 2 g/100mL 69423-0724-22 The 1 tube FDA listed
Vichy Laboratoires Normaderm Phytoaction Acne Control Moisturizer 20 mg/mL 69625-0605-01 COSMETIQUE 1 bottle FDA listed
Vichy Laboratoires Normaderm Acne Control Daily Moisturizer 20 mg/mL 69625-0617-01 Cosmetique 1 bottle FDA listed
Vichy Laboratoires Normaderm Acne Control Moisturizer 20 mg/mL 69625-0661-01 COSMETIQUE 1 bottle FDA listed
CVS Health Advanced Acne Spot Treatment 20 mg/mL 69842-0464-52 CVS 1 tube FDA listed
Neutrogena Rapid Clear Acne Eliminating Spot 20 mg/mL 69968-0472-01 Kenvue 1 tube FDA listed
Clean and Clear Acne Spot Treatment 20 mg/mL 69968-0804-01 Kenvue 1 tube FDA listed
Neutrogena Rapid Clear Acne Eliminating Spot 20 mg/mL 69968-0825-01 Kenvue 1 tube FDA listed
Clean and Clear Acne Spot Treatment 20 mg/g 69968-1016-01 Kenvue 1 tube FDA listed
Treat So Deep Acne-Fighting Treatment 2 g/100mL 70626-0106-15 ASPIRE 1 tube FDA listed
Acne Treatment Maximum Strength 2 g/100g 70631-0358-02 Young 1 tube FDA listed
Acne Spot Treatment 2 g/100mL 70764-0105-51 CONTROL 1 bottle FDA listed
innisfree Gentle Retinol Salicylic Acne Serum 1 g/50mL 71220-0088-02 Innisfree 1 tube FDA listed
Peace Out Acne Moisturizer 20 mg/mL 71494-0008-01 Peace 1 jar FDA listed
Acne Gel Pen 20 mg/mL 71714-0004-01 Tiege 1.3 ml FDA listed
Eradikate Acne Mark Fading 2 g/100mL 72204-0903-02 Rare 1 bottle FDA listed
ULTA All Clear SERUM 20 mg/g 79959-0011-01 APR 1 tube FDA listed
The INKEY List C 50 Serum 20 mg/mL 81136-0020-01 Brand 1 bottle FDA listed
The INKEY List Beta Hydroxy Acid Serum 20 mg/mL 81136-0021-01 Brand 1 bottle FDA listed
Vichy Laboratoires Normaderm Acne Control Daily Moisturizer 20 mg/mL 82046-0617-01 LOreal 1 bottle FDA listed
Curology Acne-Clearing Gel Serum 2 g/100mL 82575-0500-00 Curology, 1 tube FDA listed
Good Molecules Maximum Strength Acne Gel Cream 2 g/100mL 82730-0102-01 Good 1 tube FDA listed
Starface Acne Spot Treatment 20 mg/mL 83171-0003-01 Starface 1 tube FDA listed
Dermacleanse Acne Spot Treatment .02 g/mL 83313-0062-01 ZENMED 30 ml FDA listed
Skinkure Acne Eraser Spot Treatment 20 mg/mL 83865-0100-10 SKINKURE, 30 ml FDA listed
Tula Skincare Clear It Up Acne Clearing and Tone Correcting Gel 2 g/100mL 84126-0121-15 The 1 tube FDA listed
SEYTU Spot 2 g/100mL 84271-0002-00 Omnilife 1 tube FDA listed
Perricone MD Acne Relief Maximum Strength Spot Gel 2 g/100g 84448-0538-14 THG 1 tube FDA listed
Nativae Milia Acne Serum 20 mg/mL 85065-0557-00 CDE 30 ml FDA listed
TRSTAY LUXE Clarifying Acne Repair Serum .02 g/mL 85277-0001-01 Guangdong 1 bottle FDA listed
Duolaq 20 mg/mL 87110-0001-01 METHODIQ 1 bottle FDA listed
HerbaGlow Baiwooxia Anti-Acne Gel 2 g/100g 87351-0087-01 Kungpo 1 jar FDA listed
The Acne Spot Treatment 2 g/100gthis 87415-0100-04 Spotless, 1 tube FDA listed
Acne Treatment 2 g/100mL 87799-0999-10 Bio 30 ml FDA listed
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2026
On the market since
May 2026
📍
2026
Currently FDA-listed
listed with the FDA
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
87415-0100-04 You're viewing this 1 TUBE in 1 CARTON (87415-100-04) / 12.48 g in 1 TUBE 2026-05-21 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 87415-100-04, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 87415-0100-04, written without dashes as 87415010004. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 87415-0100-04, the first segment (87415) is the labeler code FDA assigned to Spotless, Inc.; the middle segment (0100) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (04) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Spotless, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Spotless, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage 6 words

Uses • for treatment of acne

⏱️ Dosage and Administration 4 words

Drug Facts Drug Facts

⚠️ Warnings 77 words

Warnings For external use only Flammable, keep away from open fire or flame When using this product skin irritation and dryness is more likely to occur if you use another topical medication at the same time. If irritation occurs, only use one topical acne medication at a time. Keep out of reach of children. If swallowed, get medical help or contact Poison Control Center right away. Avoid contact with eyes. If contact occurs, flush thoroughly with water.

🧪 Active Ingredient 5 words

Active ingredients Salicylic Acid 2%

🧪 Inactive Ingredients 30 words

Inactive ingredients Water, Niacinamide, Glycerin, Pentylene Glycol, Sodium Polyacrylate, Polyacrylate Crosspolymer-6, Epigallocatechin Gallatyl Glucoside, Epigallocatechin Gallate, Madecassoside, Zinc PCA, Sphingomonas Ferment Extract, Panthenol, Sodium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Ethylhexylglycerin, Tocopherol

🎯 Purpose 3 words

Purpose Acne Medication

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.