J2021
J2021 – Injection, linezolid (hospira) not therapeutically equivalent to j2020, · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 2 NDCs crosswalked per 200 MG $34.175/unit ASP+6%
📋 J2021 summary
J2021 is a HCPCS Level II J-code used to bill linezolid (hospira) not therapeutically equivalent to j2020, 200 mg, billed per 200 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Code J2021
Billing unit 200 MG Payment limit $34.175/unit NDC-Crosswalk 2
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ2021
DescriptorInjection, linezolid (hospira) not therapeutically equivalent to j2020, 200 mg
Billing unit200 MG
Payment limit / unit$34.175
Est. ASP / unit$32.241 est.
Mapped NDCs2
Data periodQ3 2026
Last updated2026-08-20
💊 About Linezolid DRUG GUIDE
Linezolid — available as Zyvox and in generic forms — is used to treat infections caused by certain drug-resistant Gram-positive bacteria.
It is approved for adults and children for nosocomial pneumonia (hospital-acquired lung infection), community-acquired pneumonia, complicated skin and skin structure infections (including diabetic foot infections, but only when bone infection is not also present), uncomplicated skin and skin structure infections, and vancomycin-resistant Enterococcus faecium infections.It is important to know that linezolid does not work against Gram-negative bacteria.
If a Gram-negative infection is also present or suspected, a separate antibiotic must be started right away.
Linezolid should only be used for infections that are confirmed or strongly suspected to be caused by bacteria, to help prevent antibiotic resistance.
Clinical overview from our editorial drug guide for Linezolid. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$34.175
Est. ASP / unit
$32.241 est.
Est. after 2% sequester
$33.492
HCPCS dosage
200 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, linezolid (hospira) not therapeutically equivalent to j2020, 200 mg
CoverageC — Carrier/MAC judgment
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment groupYY
Action codeP — Payment change
Effective date2024-01-01
Date added2023-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J2021 = 200 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J2021 WITH EST. MEDICARE PAY
2 NDCs map to J2021. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($34.175/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00409-4883-01 | Linezolid | Pfizer | — | — | 30 | $1,025.25 | — | — | CMS + PDAC |
| 00409-4883-10 | Linezolid 2 mg/mL INJECTION, SOLUTION | Hospira, | 10 POUCH in 1 CASE (0409-4883-10) / 1 BAG... | 2 mg/mL | 30 | $1,025.25 | — | ● Active | CMS + PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
🗺️ Where J2021 is utilized
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The geographic utilization map is building for this code — it aggregates millions of CMS Part B claim lines, then caches the result. Refresh in a moment; if it doesn’t appear, this code may have no reportable Part B utilization.
📊 What bills under J2021
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
2 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
No reportable utilization
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J2021 billing FAQ
What is HCPCS code J2021?
J2021 is a HCPCS Level II J-code used to bill Injection, linezolid (hospira) not therapeutically equivalent to j2020, 200 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J2021?
One unit of J2021 represents 200 MG. Report the number of units equal to the dose administered divided by 200 MG.
How many units of J2021 should I bill?
Divide the dose administered by the code's unit size (200 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J2021?
The Medicare Part B payment limit is $34.175 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $33.492 per unit. Payment limits are revised quarterly.
Which NDCs bill under J2021?
2 NDCs currently map to J2021 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J2021 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.