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Hydrocortisone acetate 0.0055 MG/MG / lidocaine hydrochloride 0.028 MG/MG Rectal Gel — RxCUI 1012221

Name: Hydrocortisone acetate 0.0055 MG/MG / lidocaine hydrochloride 0.028 MG/MG Rectal Gel (RxCUI 1012221)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1012221 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 2 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1012221

Official nameHydrocortisone acetate 0.0055 MG/MG / lidocaine hydrochloride 0.028 MG/MG Rectal Gel

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known ashydrocortisone acetate 0.55 % / lidocaine hydrochloride 2.8 % Rectal Gel; lidocaine HCl 2.8 % / hydrocortisone acetate 0.55 % Rectal Gel

FDA products mapped1

Package NDCs mapped2

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Lidocaine Transdermal Patch: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It relieves nerve pain from post-herpetic neuralgia, the lingering pain that can follow shingles. It is used in adults. It numbs the pain signals in the skin under the patch.
Usually up to 12 hours in a 24-hour period, then 12 hours off. Put it on intact skin over the most painful spot. Do not use more patches than prescribed.
No. Heat can increase how much lidocaine gets absorbed. With Ztlido, you can apply a patch after brief heat, but never put a heating pad or electric blanket directly on it.
For Ztlido, light exercise and short water exposure, like a 10-minute shower, are okay. Gently pat it dry rather than rubbing. If the edges lift, press them down.

📖 Read our full Lidocaine Transdermal Patch guide →

🕸️ Concept Web — How Hydrocortisone acetate 0.0055 MG/MG / lidocaine... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Hydrocortisone acetate 0.0055 MG/MG / lidocaine hydrochloride 0.028 MG/MG Rectal Gel RxCUI 1012221 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 5

The active substance itself — no strength, form, or brand attached yet.
- Hydrocortisone 5492 IN
- Lidocaine 6387 IN
- Hydrocortisone / lidocaine 106964 MIN
- Hydrocortisone acetate 27197 PIN
- Lidocaine hydrochloride 142440 PIN
Dose forms 6

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Hydrocortisone / lidocaine Rectal Gel 603799 SCDF
- Hydrocortisone acetate / lidocaine hydrochloride Rectal Gel 2646728 SCDFP
- Hydrocortisone / lidocaine Rectal Product 1163416 SCDG
- Hydrocortisone acetate / lidocaine hydrochloride Rectal Product 2663286 SCDGP
- Rectal Gel 346170 DF
- Rectal Product 1151127 DFG
Clinical & branded drugs 2

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Hydrocortisone acetate 0.0055 MG/MG 1012219 SCDC
- Lidocaine hydrochloride 0.028 MG/MG 1012220 SCDC

Showing up to 8 concepts per family — 13 of 13 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Hydrocortisone acetate 0.0055 MG/MG SCDC · 1012219
Lidocaine hydrochloride 0.028 MG/MG SCDC · 1012220
Hydrocortisone / lidocaine Rectal Gel SCDF · 603799
Hydrocortisone acetate / lidocaine hydrochloride Rectal Gel SCDFP · 2646728
Hydrocortisone / lidocaine Rectal Product SCDG · 1163416
Hydrocortisone acetate / lidocaine hydrochloride Rectal Product SCDGP · 2663286

📦 FDA Products & Package NDCs

1 product · 2 package NDCs

2 package NDCs map to RxCUI 1012221 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
59088-0817-01	1 TUBE in 1 KIT (59088-817-01) / 100 g in 1 TUBE (59088-817...	Lidocaine HCl - Hydrocortisone Acetate with Aloe	PureTek Corporation	2011-07-01
59088-0817-07	100 g in 1 TUBE (59088-817-07)	Lidocaine HCl - Hydrocortisone Acetate with Aloe	PureTek Corporation	2011-07-01

Observed labelers: PureTek Corporation (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.